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The map label for this gene is regX3 [H]

Identifier: 116624116

GI number: 116624116

Start: 6353269

End: 6353943

Strand: Direct

Name: regX3 [H]

Synonym: Acid_5032

Alternate gene names: 116624116

Gene position: 6353269-6353943 (Clockwise)

Preceding gene: 116624113

Following gene: 116624117

Centisome position: 63.75

GC content: 67.11

Gene sequence:

>675_bases
GTGCCTCGCATCCTCGTCGTCGAAGACGATCAGCGGACCGCCGAGTCCATCAAGCTCTACCTCGAACACGACGGCTTCGA
AGCACGCCTCGCCGCCGACGGCCTCTCCGCCCTGGAACTTTGCCGCACCACCGCGCCCGACCTTGTCATCCTGGACCGCA
TGCTCCCCCTCGTCGATGGCGCCGAAATCTGCCGTCGCTTGCGCGCCGCCGGCAACATCCCCATCATCATGCTCACCGCC
CGCACCACCGAAGCCGACAAGCTTGAGGGACTGCGCCTCGGCGCCGACGACTACGTCACCAAGCCCTTCAGCCCCCGCGA
ACTCGTGGCGCGCGTCCACGCCGTCCTGCGCCGCGCCGCCCCCGCGCCCGCTCCGCGCTTCGCCGCGATTGCAATCGATT
TCGAACGCGGAACGCTCCACCGTCACGGCGAACCCATTGCGCTCACCACCACCGAATTCAAGCTGCTCGAAACCCTCTGC
CGCGCGCCCGGCCGTATCTTTTCCCGCTCGGAACTCCTGGAGCGCATCTTCGGCTGGGACTACGAAGGCACGGAGCGCAC
CGTGGACGTCCACATCGCCAACCTGCGCCGCAAAATTGACGACAATCCCGCGCAGCCCGCGCTCATCGCCACGATCTTCG
GCGCCGGCTACAAATGGATCGGCGGACCCTCGTGA

Upstream 100 bases:

>100_bases
CTGGTGAATCTCCTGTTGCAGTCTTCCTGCCATGAATCCATAATATTCGTTGATAACGACTATCGTCAATAAGGGATTAT
CCCCGTGCTACGATCTGCTC

Downstream 100 bases:

>100_bases
AGATTAGCCTCCGATTGCGATTCCTGCTGGCCACCATGGCAATCGCCGGCGCCACGCTTACGGCCATCGCACTCTTCTCC
AGCCGGGTTACCCTCAGCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MPRILVVEDDQRTAESIKLYLEHDGFEARLAADGLSALELCRTTAPDLVILDRMLPLVDGAEICRRLRAAGNIPIIMLTA
RTTEADKLEGLRLGADDYVTKPFSPRELVARVHAVLRRAAPAPAPRFAAIAIDFERGTLHRHGEPIALTTTEFKLLETLC
RAPGRIFSRSELLERIFGWDYEGTERTVDVHIANLRRKIDDNPAQPALIATIFGAGYKWIGGPS

Sequences:

>Translated_224_residues
MPRILVVEDDQRTAESIKLYLEHDGFEARLAADGLSALELCRTTAPDLVILDRMLPLVDGAEICRRLRAAGNIPIIMLTA
RTTEADKLEGLRLGADDYVTKPFSPRELVARVHAVLRRAAPAPAPRFAAIAIDFERGTLHRHGEPIALTTTEFKLLETLC
RAPGRIFSRSELLERIFGWDYEGTERTVDVHIANLRRKIDDNPAQPALIATIFGAGYKWIGGPS
>Mature_223_residues
PRILVVEDDQRTAESIKLYLEHDGFEARLAADGLSALELCRTTAPDLVILDRMLPLVDGAEICRRLRAAGNIPIIMLTAR
TTEADKLEGLRLGADDYVTKPFSPRELVARVHAVLRRAAPAPAPRFAAIAIDFERGTLHRHGEPIALTTTEFKLLETLCR
APGRIFSRSELLERIFGWDYEGTERTVDVHIANLRRKIDDNPAQPALIATIFGAGYKWIGGPS

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=42.6008968609865, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=42.5438596491228, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=39.4618834080717, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=39.0134529147982, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1786784, Length=219, Percent_Identity=39.7260273972603, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=35.9307359307359, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=37.4449339207048, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=38.9908256880734, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=39.5454545454545, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=37.0044052863436, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=37.280701754386, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=36.0730593607306, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=34.1991341991342, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=34.4978165938865, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=34.4827586206897, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=35.6435643564356, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24862; Mature: 24731

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRILVVEDDQRTAESIKLYLEHDGFEARLAADGLSALELCRTTAPDLVILDRMLPLVDG
CCEEEEEECCCHHHHHEEEEEECCCCEEEEHHCCHHHHHHHHCCCCCHHHHHHHHHHCCH
AEICRRLRAAGNIPIIMLTARTTEADKLEGLRLGADDYVTKPFSPRELVARVHAVLRRAA
HHHHHHHHHCCCCCEEEEEECCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
PAPAPRFAAIAIDFERGTLHRHGEPIALTTTEFKLLETLCRAPGRIFSRSELLERIFGWD
CCCCCCEEEEEEEECCCCHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
YEGTERTVDVHIANLRRKIDDNPAQPALIATIFGAGYKWIGGPS
CCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PRILVVEDDQRTAESIKLYLEHDGFEARLAADGLSALELCRTTAPDLVILDRMLPLVDG
CEEEEEECCCHHHHHEEEEEECCCCEEEEHHCCHHHHHHHHCCCCCHHHHHHHHHHCCH
AEICRRLRAAGNIPIIMLTARTTEADKLEGLRLGADDYVTKPFSPRELVARVHAVLRRAA
HHHHHHHHHCCCCCEEEEEECCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
PAPAPRFAAIAIDFERGTLHRHGEPIALTTTEFKLLETLCRAPGRIFSRSELLERIFGWD
CCCCCCEEEEEEEECCCCHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
YEGTERTVDVHIANLRRKIDDNPAQPALIATIFGAGYKWIGGPS
CCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA