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The map label for this gene is dapE [H]

Identifier: 116624041

GI number: 116624041

Start: 6252275

End: 6253669

Strand: Reverse

Name: dapE [H]

Synonym: Acid_4955

Alternate gene names: 116624041

Gene position: 6253669-6252275 (Counterclockwise)

Preceding gene: 116624043

Following gene: 116624040

Centisome position: 62.75

GC content: 63.01

Gene sequence:

>1395_bases
ATGCGAGCCGCAGCGTCACTCCTTTTCATCGCGATTCTATCGGCCAGCGCGCAGACTCCGGATTGGCCGAAAGTCAACGA
AGAAGCCATGCGCCACTTTCAGGCGCTCATCCAGATCGATTCCACCGACCCGCCGGGCAATGAGACCCGCGTGGTGGATT
ACGTCCGCAAGGTCTTCGACGCCGAAGGCATCCCGTACATCGTCGCCGCCAAAGATCCCGCGCGCGCCAACATCATCGCG
CGGCTCAAGGGCAGCGGCGCAAAGCGGCCGCTGCTGATCGTTGGCCACAGCGACACCGTCAAAGTGGACGCCTCCAAGTG
GACCTTCCCGCCATTCAGCGGCGCGCGCAACGGAGGCTACGTCTATGGGCGCGGCACGCTGGACGACAAGCCCAACCTGA
TGGCCGCCATGATGACCATGGTGCTGCTGAAGCGCTCCCACGCCGGGCTCGATCGCGACGTCATCTTTCTTTCCGAAGCC
GGCGAAGAGGCTGCAACCGGGCCTGGTATTCAATACATCGTGAACGAGCACTTCGCCGATATCGATGCCGAGATCGCGCT
CGCCGAGGGCGGCGGGGTGCGGCGTCAAAACGGCAAGGTGAGTTACGCCGTCGTGCAGACCACGGAGAAGCGCCCGGCCG
CCGCGCGGCTCGTGTCCCATGGTCCCGCCGGCCACGGTTCGCGGCCAATGCGCACCAACGCCATCCTCCACCTCTCGCGC
GCGGTCGAGAAGGTTGCCATGTGGGATCCGCCGATGCGCTTCAACGACACCACGCGATATTATTTCGAAAAGCTGGCCAC
AATCAGCACTCCGGATCAGGCCGCGCGCTACCAGGGCCTCTTCGACCCTACTAAAGCCCCCGCCATCCGCGAGTATCTCG
CCGAGAACGATCCCGGCGCTTACTCCATGCTGCACACTTCGATTTCGCCCAACATTATCCAGGCCGGCTTCCAGGTCAAC
GTGATCCCCTCCGAAGCCACCGCCACCCTCGATATCCGCGCGCTCCCCGACGAGGATATGGCCGCCTTCCTCAACCTCAT
GCGCAAGGTCATCGACGATCCCACGGTCGAAGTGGTTTCCGAGGCCCGGAACCAGCGTCCCGGCGCGGCTCCATCGCGGA
TCGATTCGGACGCCTATCACGCGATCGAAGCTGCCTTCAACAAGGTCTATGGCGCGACCACGCTGCCGATGATGTCAACT
GGCGCGACCGATATGGCCTTCCTCCGGTCCAAGGGCATCCAGTGCTACGGCATTGGCGCCATGACCGATATGGAAGACGC
CGGCAAGGGCTTCGGAGCCCACAGCGACCAGGAACGCATCCTCGAAGAATCGGTCTATAAGCATGTCCAGTTCTTCTGGG
CCGCCGTCACTTCCATCGCGGGATCGAAACCGTAA

Upstream 100 bases:

>100_bases
GGCGAAGCAAAAGCCAAGTCGAAGTCGGGCGCGGGTCATGGGAACTCCTTGTCTTAGAAAACTAGCACAGTCGGGTCGCC
GAGCACGCTACACTCTGATA

Downstream 100 bases:

>100_bases
AATTCAGCACCGTAACGTTGGGCTATGTCCCGACGCCTATACGGGCACGATGACAAAAAAACTACTTGTGGTAGTAACGA
TTGTGCTTGCCTTCACGATC

Product: peptidase M20

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MRAAASLLFIAILSASAQTPDWPKVNEEAMRHFQALIQIDSTDPPGNETRVVDYVRKVFDAEGIPYIVAAKDPARANIIA
RLKGSGAKRPLLIVGHSDTVKVDASKWTFPPFSGARNGGYVYGRGTLDDKPNLMAAMMTMVLLKRSHAGLDRDVIFLSEA
GEEAATGPGIQYIVNEHFADIDAEIALAEGGGVRRQNGKVSYAVVQTTEKRPAAARLVSHGPAGHGSRPMRTNAILHLSR
AVEKVAMWDPPMRFNDTTRYYFEKLATISTPDQAARYQGLFDPTKAPAIREYLAENDPGAYSMLHTSISPNIIQAGFQVN
VIPSEATATLDIRALPDEDMAAFLNLMRKVIDDPTVEVVSEARNQRPGAAPSRIDSDAYHAIEAAFNKVYGATTLPMMST
GATDMAFLRSKGIQCYGIGAMTDMEDAGKGFGAHSDQERILEESVYKHVQFFWAAVTSIAGSKP

Sequences:

>Translated_464_residues
MRAAASLLFIAILSASAQTPDWPKVNEEAMRHFQALIQIDSTDPPGNETRVVDYVRKVFDAEGIPYIVAAKDPARANIIA
RLKGSGAKRPLLIVGHSDTVKVDASKWTFPPFSGARNGGYVYGRGTLDDKPNLMAAMMTMVLLKRSHAGLDRDVIFLSEA
GEEAATGPGIQYIVNEHFADIDAEIALAEGGGVRRQNGKVSYAVVQTTEKRPAAARLVSHGPAGHGSRPMRTNAILHLSR
AVEKVAMWDPPMRFNDTTRYYFEKLATISTPDQAARYQGLFDPTKAPAIREYLAENDPGAYSMLHTSISPNIIQAGFQVN
VIPSEATATLDIRALPDEDMAAFLNLMRKVIDDPTVEVVSEARNQRPGAAPSRIDSDAYHAIEAAFNKVYGATTLPMMST
GATDMAFLRSKGIQCYGIGAMTDMEDAGKGFGAHSDQERILEESVYKHVQFFWAAVTSIAGSKP
>Mature_464_residues
MRAAASLLFIAILSASAQTPDWPKVNEEAMRHFQALIQIDSTDPPGNETRVVDYVRKVFDAEGIPYIVAAKDPARANIIA
RLKGSGAKRPLLIVGHSDTVKVDASKWTFPPFSGARNGGYVYGRGTLDDKPNLMAAMMTMVLLKRSHAGLDRDVIFLSEA
GEEAATGPGIQYIVNEHFADIDAEIALAEGGGVRRQNGKVSYAVVQTTEKRPAAARLVSHGPAGHGSRPMRTNAILHLSR
AVEKVAMWDPPMRFNDTTRYYFEKLATISTPDQAARYQGLFDPTKAPAIREYLAENDPGAYSMLHTSISPNIIQAGFQVN
VIPSEATATLDIRALPDEDMAAFLNLMRKVIDDPTVEVVSEARNQRPGAAPSRIDSDAYHAIEAAFNKVYGATTLPMMST
GATDMAFLRSKGIQCYGIGAMTDMEDAGKGFGAHSDQERILEESVYKHVQFFWAAVTSIAGSKP

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI269846968, Length=424, Percent_Identity=25.9433962264151, Blast_Score=96, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 50404; Mature: 50404

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAASLLFIAILSASAQTPDWPKVNEEAMRHFQALIQIDSTDPPGNETRVVDYVRKVFD
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHC
AEGIPYIVAAKDPARANIIARLKGSGAKRPLLIVGHSDTVKVDASKWTFPPFSGARNGGY
CCCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCE
VYGRGTLDDKPNLMAAMMTMVLLKRSHAGLDRDVIFLSEAGEEAATGPGIQYIVNEHFAD
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC
IDAEIALAEGGGVRRQNGKVSYAVVQTTEKRPAAARLVSHGPAGHGSRPMRTNAILHLSR
CCCEEEEECCCCEECCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AVEKVAMWDPPMRFNDTTRYYFEKLATISTPDQAARYQGLFDPTKAPAIREYLAENDPGA
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
YSMLHTSISPNIIQAGFQVNVIPSEATATLDIRALPDEDMAAFLNLMRKVIDDPTVEVVS
EEEEECCCCCCHHHCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHH
EARNQRPGAAPSRIDSDAYHAIEAAFNKVYGATTLPMMSTGATDMAFLRSKGIQCYGIGA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHCCCEEEEECC
MTDMEDAGKGFGAHSDQERILEESVYKHVQFFWAAVTSIAGSKP
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRAAASLLFIAILSASAQTPDWPKVNEEAMRHFQALIQIDSTDPPGNETRVVDYVRKVFD
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHC
AEGIPYIVAAKDPARANIIARLKGSGAKRPLLIVGHSDTVKVDASKWTFPPFSGARNGGY
CCCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCE
VYGRGTLDDKPNLMAAMMTMVLLKRSHAGLDRDVIFLSEAGEEAATGPGIQYIVNEHFAD
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC
IDAEIALAEGGGVRRQNGKVSYAVVQTTEKRPAAARLVSHGPAGHGSRPMRTNAILHLSR
CCCEEEEECCCCEECCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AVEKVAMWDPPMRFNDTTRYYFEKLATISTPDQAARYQGLFDPTKAPAIREYLAENDPGA
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
YSMLHTSISPNIIQAGFQVNVIPSEATATLDIRALPDEDMAAFLNLMRKVIDDPTVEVVS
EEEEECCCCCCHHHCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHH
EARNQRPGAAPSRIDSDAYHAIEAAFNKVYGATTLPMMSTGATDMAFLRSKGIQCYGIGA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHCCCEEEEECC
MTDMEDAGKGFGAHSDQERILEESVYKHVQFFWAAVTSIAGSKP
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA