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The map label for this gene is yfnA [H]

Identifier: 116624032

GI number: 116624032

Start: 6241061

End: 6242500

Strand: Direct

Name: yfnA [H]

Synonym: Acid_4944

Alternate gene names: 116624032

Gene position: 6241061-6242500 (Clockwise)

Preceding gene: 116624031

Following gene: 116624033

Centisome position: 62.63

GC content: 60.14

Gene sequence:

>1440_bases
ATGAGTAGTCAACTCTTTGGGACGAAATCGCTAAGCCGGATTATTGCCGAGTCCGAGGGCGGTGAGCATCATTTAAAGAA
GACGCTGGGACCCGTCAACCTGGTGGCGCTCGGAATCGGCGCCATCATCGGGGCCGGCCTGTTCTCGCTCACGGGAATCG
CCGCGGCGGACAACGCGGGTCCGGCGGTGGTCCTCTCCTTCATCGTCGCCGCCATCGGCTGCGCCTTCGCGGGCATGTGC
TACAGCGAATTCTCCACCATGATCCCCATTGCCGGCAGCGCGTACACCTACGCCTACGCGACCATGGGCGAACTGCTCGC
GTGGATCATCGGCTGGGATCTGGTGCTCGAGTACGCCGTCGGCGCCGCCACGGTATCGGTAAGCTGGTCGAGTTACGTGG
TCAAGCTGCTCCAGTCCTTCAGCATCGAGTTGCCCTCCAGCTTCATTCACTGCCCCTGGGATGAAGTGCCCGGCATCATC
AACCTCCCGGCCGTATTGATCGTCTGCGCCATCTCCATCCTGTTGATGATCGGTATCTCGGAATCGGCCAAGGTCAACGC
GGTGATCGTGGTGGTCAAAGTCGCGATCGTGATCGTGGTGATCGCGGTCGGCTACTCGTACATCAAACCGGAAAATTACA
CGCCCTTCATTCCTCCAAACACGGGCACCTTCGGCGAATTCGGCTTTAGCGGTGTGATGCGCGCGGCGGCCGTGATCTTC
TTCGCGTACATCGGCTTTGACGCGGTCTCCACCGCGGCGCAGGAAGCCAAGAAGCCGCAGCGGGACATGCCAATCGGCAT
CATCGGCTCGCTGATCGTCTGCACTATCCTCTATATCCTGTTTGCCCGCGTCCTCACCGGCATGGTCAACTACAAGACCT
TCCACGGCGATGCCTCACCGGTCGCCACCGTGATCCACCTCTTCCCCTCGGTCGCGCTTCAGACCACCATCGTGATCGGC
ATCATCGCCGGCTACACTTCGGTGATCCTGGTCATGCTCCTCGGCCAGTCGCGCGTGTTCTTCTCGATGTCGAAGGATGG
CTTGCTCCCCGCCGTGTTCAGCGACATTCACCCCAAATTCCAGACCCCGTGGCGCTGCAACATGATCTTCATGGTCTTCG
TTTCGCTCTTCTCCGGCTTCCTACCGATTGCGAAGCTCGGCCACATGACCAGCATCGGCACGCTGCTCGCCTTCGTGATC
GTCTGCATCGGCATCATCTGGATGCGCAAGACCAATCCGAATGCGCCACGTCCGTATCGTACGCCGTTCGTACCGGTCGT
CCCAATTCTGGGTGTCCTGGTCTGCTTCGCAATGATGGCGTCGCTCGGCGCCGAAACCTGGATCCGGCTCTTCGTATGGC
TCGCCATCGGCCTCGTCATCTACTTCACCTATGGCGTCAAGAACAGCCACCTGCGCAAGGCCCCGCTCAATAAGCGCTAA

Upstream 100 bases:

>100_bases
TTTTGCTGTTGGCGTACAAACCGAACTACACGTGGCCGGGCCTGATCATCGTGCTGCTGGGCCTGCCCGTTTACTTTATT
TGGCGAGGGAAAGCGACAAT

Downstream 100 bases:

>100_bases
CCCGCTGCTGCTCGCGTGCGCGATCGTTGGGATCGCGCACGCGCAGCAGTCCCAAAATCCTTCGCCCATGGTGGAGCACA
CCAGGGCTCATCCCCGCATC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSSQLFGTKSLSRIIAESEGGEHHLKKTLGPVNLVALGIGAIIGAGLFSLTGIAAADNAGPAVVLSFIVAAIGCAFAGMC
YSEFSTMIPIAGSAYTYAYATMGELLAWIIGWDLVLEYAVGAATVSVSWSSYVVKLLQSFSIELPSSFIHCPWDEVPGII
NLPAVLIVCAISILLMIGISESAKVNAVIVVVKVAIVIVVIAVGYSYIKPENYTPFIPPNTGTFGEFGFSGVMRAAAVIF
FAYIGFDAVSTAAQEAKKPQRDMPIGIIGSLIVCTILYILFARVLTGMVNYKTFHGDASPVATVIHLFPSVALQTTIVIG
IIAGYTSVILVMLLGQSRVFFSMSKDGLLPAVFSDIHPKFQTPWRCNMIFMVFVSLFSGFLPIAKLGHMTSIGTLLAFVI
VCIGIIWMRKTNPNAPRPYRTPFVPVVPILGVLVCFAMMASLGAETWIRLFVWLAIGLVIYFTYGVKNSHLRKAPLNKR

Sequences:

>Translated_479_residues
MSSQLFGTKSLSRIIAESEGGEHHLKKTLGPVNLVALGIGAIIGAGLFSLTGIAAADNAGPAVVLSFIVAAIGCAFAGMC
YSEFSTMIPIAGSAYTYAYATMGELLAWIIGWDLVLEYAVGAATVSVSWSSYVVKLLQSFSIELPSSFIHCPWDEVPGII
NLPAVLIVCAISILLMIGISESAKVNAVIVVVKVAIVIVVIAVGYSYIKPENYTPFIPPNTGTFGEFGFSGVMRAAAVIF
FAYIGFDAVSTAAQEAKKPQRDMPIGIIGSLIVCTILYILFARVLTGMVNYKTFHGDASPVATVIHLFPSVALQTTIVIG
IIAGYTSVILVMLLGQSRVFFSMSKDGLLPAVFSDIHPKFQTPWRCNMIFMVFVSLFSGFLPIAKLGHMTSIGTLLAFVI
VCIGIIWMRKTNPNAPRPYRTPFVPVVPILGVLVCFAMMASLGAETWIRLFVWLAIGLVIYFTYGVKNSHLRKAPLNKR
>Mature_478_residues
SSQLFGTKSLSRIIAESEGGEHHLKKTLGPVNLVALGIGAIIGAGLFSLTGIAAADNAGPAVVLSFIVAAIGCAFAGMCY
SEFSTMIPIAGSAYTYAYATMGELLAWIIGWDLVLEYAVGAATVSVSWSSYVVKLLQSFSIELPSSFIHCPWDEVPGIIN
LPAVLIVCAISILLMIGISESAKVNAVIVVVKVAIVIVVIAVGYSYIKPENYTPFIPPNTGTFGEFGFSGVMRAAAVIFF
AYIGFDAVSTAAQEAKKPQRDMPIGIIGSLIVCTILYILFARVLTGMVNYKTFHGDASPVATVIHLFPSVALQTTIVIGI
IAGYTSVILVMLLGQSRVFFSMSKDGLLPAVFSDIHPKFQTPWRCNMIFMVFVSLFSGFLPIAKLGHMTSIGTLLAFVIV
CIGIIWMRKTNPNAPRPYRTPFVPVVPILGVLVCFAMMASLGAETWIRLFVWLAIGLVIYFTYGVKNSHLRKAPLNKR

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=433, Percent_Identity=30.715935334873, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=32.6388888888889, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=32.6388888888889, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI258614005, Length=420, Percent_Identity=29.7619047619048, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI258614003, Length=420, Percent_Identity=29.7619047619048, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI258645169, Length=420, Percent_Identity=29.7619047619048, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI110347453, Length=405, Percent_Identity=33.3333333333333, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI181337167, Length=402, Percent_Identity=32.089552238806, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI115648063, Length=420, Percent_Identity=24.7619047619048, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI115648022, Length=420, Percent_Identity=24.7619047619048, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI186910308, Length=420, Percent_Identity=24.7619047619048, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI186910306, Length=420, Percent_Identity=24.7619047619048, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI186910304, Length=420, Percent_Identity=24.7619047619048, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI71979932, Length=445, Percent_Identity=24.0449438202247, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI7657683, Length=388, Percent_Identity=23.4536082474227, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI33286428, Length=429, Percent_Identity=24.4755244755245, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI187423910, Length=483, Percent_Identity=22.5672877846791, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7657591, Length=483, Percent_Identity=22.5672877846791, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI71999149, Length=413, Percent_Identity=24.6973365617433, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI87081869, Length=482, Percent_Identity=24.6887966804979, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87082250, Length=438, Percent_Identity=25.3424657534247, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082023, Length=445, Percent_Identity=24.0449438202247, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI2367353, Length=479, Percent_Identity=23.1732776617954, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786694, Length=397, Percent_Identity=25.1889168765743, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786302, Length=441, Percent_Identity=21.9954648526077, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081708, Length=479, Percent_Identity=21.7118997912317, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789017, Length=356, Percent_Identity=24.7191011235955, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786602, Length=482, Percent_Identity=22.8215767634855, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788480, Length=519, Percent_Identity=20.0385356454721, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786789, Length=430, Percent_Identity=21.8604651162791, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=391, Percent_Identity=32.9923273657289, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17531343, Length=404, Percent_Identity=31.4356435643564, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17533459, Length=405, Percent_Identity=30.8641975308642, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17540018, Length=433, Percent_Identity=25.1732101616628, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17568033, Length=456, Percent_Identity=26.0964912280702, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566699, Length=315, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17537453, Length=284, Percent_Identity=24.2957746478873, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71993915, Length=419, Percent_Identity=24.3436754176611, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666159, Length=415, Percent_Identity=35.1807228915663, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI221512776, Length=415, Percent_Identity=35.1807228915663, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24668806, Length=437, Percent_Identity=33.8672768878719, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI21356285, Length=437, Percent_Identity=33.8672768878719, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24668802, Length=437, Percent_Identity=33.8672768878719, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24667468, Length=398, Percent_Identity=35.678391959799, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI281366235, Length=427, Percent_Identity=31.3817330210773, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI116007820, Length=427, Percent_Identity=31.3817330210773, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI116007818, Length=429, Percent_Identity=32.8671328671329, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI85725152, Length=429, Percent_Identity=32.8671328671329, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI161077963, Length=430, Percent_Identity=30.4651162790698, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21357367, Length=430, Percent_Identity=23.7209302325581, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221331183, Length=436, Percent_Identity=23.394495412844, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17647653, Length=436, Percent_Identity=23.394495412844, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24664379, Length=436, Percent_Identity=23.394495412844, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24651635, Length=418, Percent_Identity=23.6842105263158, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24651633, Length=418, Percent_Identity=23.6842105263158, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45550968, Length=421, Percent_Identity=25.1781472684086, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19921172, Length=421, Percent_Identity=25.1781472684086, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51447; Mature: 51316

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQLFGTKSLSRIIAESEGGEHHLKKTLGPVNLVALGIGAIIGAGLFSLTGIAAADNAG
CCCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PAVVLSFIVAAIGCAFAGMCYSEFSTMIPIAGSAYTYAYATMGELLAWIIGWDLVLEYAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAATVSVSWSSYVVKLLQSFSIELPSSFIHCPWDEVPGIINLPAVLIVCAISILLMIGIS
HHHEEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCC
ESAKVNAVIVVVKVAIVIVVIAVGYSYIKPENYTPFIPPNTGTFGEFGFSGVMRAAAVIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FAYIGFDAVSTAAQEAKKPQRDMPIGIIGSLIVCTILYILFARVLTGMVNYKTFHGDASP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHH
VATVIHLFPSVALQTTIVIGIIAGYTSVILVMLLGQSRVFFSMSKDGLLPAVFSDIHPKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCC
QTPWRCNMIFMVFVSLFSGFLPIAKLGHMTSIGTLLAFVIVCIGIIWMRKTNPNAPRPYR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TPFVPVVPILGVLVCFAMMASLGAETWIRLFVWLAIGLVIYFTYGVKNSHLRKAPLNKR
CCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSQLFGTKSLSRIIAESEGGEHHLKKTLGPVNLVALGIGAIIGAGLFSLTGIAAADNAG
CCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PAVVLSFIVAAIGCAFAGMCYSEFSTMIPIAGSAYTYAYATMGELLAWIIGWDLVLEYAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAATVSVSWSSYVVKLLQSFSIELPSSFIHCPWDEVPGIINLPAVLIVCAISILLMIGIS
HHHEEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCC
ESAKVNAVIVVVKVAIVIVVIAVGYSYIKPENYTPFIPPNTGTFGEFGFSGVMRAAAVIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FAYIGFDAVSTAAQEAKKPQRDMPIGIIGSLIVCTILYILFARVLTGMVNYKTFHGDASP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHH
VATVIHLFPSVALQTTIVIGIIAGYTSVILVMLLGQSRVFFSMSKDGLLPAVFSDIHPKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCC
QTPWRCNMIFMVFVSLFSGFLPIAKLGHMTSIGTLLAFVIVCIGIIWMRKTNPNAPRPYR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TPFVPVVPILGVLVCFAMMASLGAETWIRLFVWLAIGLVIYFTYGVKNSHLRKAPLNKR
CCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]