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The map label for this gene is steT [H]

Identifier: 116624031

GI number: 116624031

Start: 6239679

End: 6241064

Strand: Direct

Name: steT [H]

Synonym: Acid_4943

Alternate gene names: 116624031

Gene position: 6239679-6241064 (Clockwise)

Preceding gene: 116624030

Following gene: 116624032

Centisome position: 62.61

GC content: 61.76

Gene sequence:

>1386_bases
ATGGCAACGACTCGTGAAGGCGGCCTGATCAAAGGACTGGGGCTCGTCGATTCCACCACGCTCGTGATGGGCTCGATGAT
CGGCTCCGGTGTGTTCATCGTCGCCGCCGATATCTCCCGGCAGGTTCAGTCACCCGGCCTCATGATGATGACGTGGTTCG
TCACCGCGCTCCTCACCCTGATCGCCGCCCTCAGCTATGGCGAGCTCGCCGCCGCCATGCCGCACGCCGGCGGACAGTAC
GTCTACCTGCGCGAGGCCTTCGGTCCGCTGTACGGGTTCCTCTACGGCTGGACGCTTTTCATGGTGATTCAGACCGGCAC
TATCGCCGCCGTCGCCGTCGCCTTCGCTAAGTACGCCGGCGTCTTCTTCCCGTGGATCAGCGATCAGAATTACCTGCTCG
GCGCCGGCAAGGTCGGGTTCACCACCCAGCAGTTGGTGGCCATCGCGATTATCGTCTTCCTCACCTGGAGCAACACTCGC
GGAATACGCACCGGCGCCATGGTGCAGAACATCTTCACCATCGCCAAGGTGGCTGCGATCCTGGGCCTGATCGCCGCCGG
ATTTTTGGTGGGACGCAATCCCGAGGCCATTGCCAGCAACTTCAACGGCTTCTGGCGCAACTCCGGCTGGAATTTCGATA
CCGTGCGGCTGGTCGGTGTCGCGATGGTCGGCTCGCTCTTCAGCAGCGACGCGTGGAATAACGTCACCTTCACGGCCGGC
GAGGTCCGTAATCCGAGGCGCAACCTGCCGCTCTCGCTCGCGCTCGGCGTCTGCATCGTCAGCGCGCTCTACATCCTCTC
CAATTTCGTGTACCTCAACGTGCTCACGTTCGACGCCATCCAGCACGCTCCCAAGGATCGAGTCGCCGCCCTCGCCGCCG
AGCACATGCTCGGCCCCGTCGCCCTGCAAATCATGGCGGCCGCCATCATGATCTCCACCTTCGGCTGCGTCAACGGCCTC
ACGCTCGCAGGCGCCCGTGTCTACTATGCGATGGCCAAGGACCGGCTCTTCTTCCGCCGCGCCACCGAACTCGACCCGAA
GACCAACGCTCCCGTCTTCTCCCTGACCGTGCAGTGCGCCTGGTCGGTGGCCCTCACGTTAAGCGGCAGTTACAACGATC
TGCTCGACTATGTTATCTTTGCTGTGCTGCTCTTCTACATTTTGACGATCGCCGGCCTGTTCGTGCTCCGTCGCACCCGT
CCGGATATGGACCGGCCCTACAAGGCAATCGGATATCCGGTGCTGCCGGCAGTTTACATTTTGGCTGCCGGACTGATCGA
AGTTTTGCTGTTGGCGTACAAACCGAACTACACGTGGCCGGGCCTGATCATCGTGCTGCTGGGCCTGCCCGTTTACTTTA
TTTGGCGAGGGAAAGCGACAATATGA

Upstream 100 bases:

>100_bases
CACTGCAGGTACTCGAAGCCGGCGCCGATTCTCTCGCCGTGATCGCCGGCCTGCTGCCCGAAAACGCTACCGCACACTCC
CTTAGGGAACGGATGGAACA

Downstream 100 bases:

>100_bases
GTAGTCAACTCTTTGGGACGAAATCGCTAAGCCGGATTATTGCCGAGTCCGAGGGCGGTGAGCATCATTTAAAGAAGACG
CTGGGACCCGTCAACCTGGT

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MATTREGGLIKGLGLVDSTTLVMGSMIGSGVFIVAADISRQVQSPGLMMMTWFVTALLTLIAALSYGELAAAMPHAGGQY
VYLREAFGPLYGFLYGWTLFMVIQTGTIAAVAVAFAKYAGVFFPWISDQNYLLGAGKVGFTTQQLVAIAIIVFLTWSNTR
GIRTGAMVQNIFTIAKVAAILGLIAAGFLVGRNPEAIASNFNGFWRNSGWNFDTVRLVGVAMVGSLFSSDAWNNVTFTAG
EVRNPRRNLPLSLALGVCIVSALYILSNFVYLNVLTFDAIQHAPKDRVAALAAEHMLGPVALQIMAAAIMISTFGCVNGL
TLAGARVYYAMAKDRLFFRRATELDPKTNAPVFSLTVQCAWSVALTLSGSYNDLLDYVIFAVLLFYILTIAGLFVLRRTR
PDMDRPYKAIGYPVLPAVYILAAGLIEVLLLAYKPNYTWPGLIIVLLGLPVYFIWRGKATI

Sequences:

>Translated_461_residues
MATTREGGLIKGLGLVDSTTLVMGSMIGSGVFIVAADISRQVQSPGLMMMTWFVTALLTLIAALSYGELAAAMPHAGGQY
VYLREAFGPLYGFLYGWTLFMVIQTGTIAAVAVAFAKYAGVFFPWISDQNYLLGAGKVGFTTQQLVAIAIIVFLTWSNTR
GIRTGAMVQNIFTIAKVAAILGLIAAGFLVGRNPEAIASNFNGFWRNSGWNFDTVRLVGVAMVGSLFSSDAWNNVTFTAG
EVRNPRRNLPLSLALGVCIVSALYILSNFVYLNVLTFDAIQHAPKDRVAALAAEHMLGPVALQIMAAAIMISTFGCVNGL
TLAGARVYYAMAKDRLFFRRATELDPKTNAPVFSLTVQCAWSVALTLSGSYNDLLDYVIFAVLLFYILTIAGLFVLRRTR
PDMDRPYKAIGYPVLPAVYILAAGLIEVLLLAYKPNYTWPGLIIVLLGLPVYFIWRGKATI
>Mature_460_residues
ATTREGGLIKGLGLVDSTTLVMGSMIGSGVFIVAADISRQVQSPGLMMMTWFVTALLTLIAALSYGELAAAMPHAGGQYV
YLREAFGPLYGFLYGWTLFMVIQTGTIAAVAVAFAKYAGVFFPWISDQNYLLGAGKVGFTTQQLVAIAIIVFLTWSNTRG
IRTGAMVQNIFTIAKVAAILGLIAAGFLVGRNPEAIASNFNGFWRNSGWNFDTVRLVGVAMVGSLFSSDAWNNVTFTAGE
VRNPRRNLPLSLALGVCIVSALYILSNFVYLNVLTFDAIQHAPKDRVAALAAEHMLGPVALQIMAAAIMISTFGCVNGLT
LAGARVYYAMAKDRLFFRRATELDPKTNAPVFSLTVQCAWSVALTLSGSYNDLLDYVIFAVLLFYILTIAGLFVLRRTRP
DMDRPYKAIGYPVLPAVYILAAGLIEVLLLAYKPNYTWPGLIIVLLGLPVYFIWRGKATI

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=464, Percent_Identity=29.7413793103448, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI7657591, Length=464, Percent_Identity=29.7413793103448, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI33286428, Length=459, Percent_Identity=29.8474945533769, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI186910308, Length=447, Percent_Identity=29.082774049217, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI186910306, Length=447, Percent_Identity=29.082774049217, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI186910304, Length=447, Percent_Identity=29.082774049217, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI115648063, Length=447, Percent_Identity=27.7404921700224, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI115648022, Length=447, Percent_Identity=27.7404921700224, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI71979932, Length=454, Percent_Identity=27.5330396475771, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI7657683, Length=420, Percent_Identity=27.1428571428571, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI9790235, Length=457, Percent_Identity=27.5711159737418, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI33286430, Length=263, Percent_Identity=29.277566539924, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4507047, Length=427, Percent_Identity=25.7611241217799, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI71999149, Length=423, Percent_Identity=24.822695035461, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI258614005, Length=431, Percent_Identity=23.8979118329466, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI258614003, Length=431, Percent_Identity=23.8979118329466, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI110347453, Length=356, Percent_Identity=27.5280898876405, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI258645169, Length=424, Percent_Identity=23.3490566037736, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI114326544, Length=442, Percent_Identity=23.5294117647059, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI114326550, Length=442, Percent_Identity=23.5294117647059, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI181337167, Length=416, Percent_Identity=24.7596153846154, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87082250, Length=470, Percent_Identity=24.0425531914894, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI2367353, Length=409, Percent_Identity=27.3838630806846, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787890, Length=409, Percent_Identity=26.6503667481663, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786602, Length=445, Percent_Identity=22.247191011236, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786908, Length=404, Percent_Identity=21.039603960396, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=463, Percent_Identity=32.1814254859611, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17568033, Length=461, Percent_Identity=31.0195227765727, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI71982612, Length=458, Percent_Identity=25.764192139738, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71982608, Length=458, Percent_Identity=25.764192139738, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32566699, Length=394, Percent_Identity=27.6649746192893, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32566695, Length=430, Percent_Identity=26.7441860465116, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI193208714, Length=421, Percent_Identity=27.0783847980998, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71982623, Length=284, Percent_Identity=28.5211267605634, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71993915, Length=405, Percent_Identity=26.9135802469136, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71990446, Length=434, Percent_Identity=25.3456221198157, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71995388, Length=407, Percent_Identity=25.5528255528256, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71995382, Length=407, Percent_Identity=25.5528255528256, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17531343, Length=411, Percent_Identity=25.7907542579075, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17533459, Length=411, Percent_Identity=24.0875912408759, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17532491, Length=399, Percent_Identity=22.0551378446115, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321492, Length=346, Percent_Identity=24.5664739884393, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321751, Length=436, Percent_Identity=22.9357798165138, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221331183, Length=450, Percent_Identity=30, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17647653, Length=450, Percent_Identity=30, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24664379, Length=450, Percent_Identity=30, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21357367, Length=471, Percent_Identity=27.8131634819533, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI45550968, Length=454, Percent_Identity=29.295154185022, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI19921172, Length=454, Percent_Identity=29.295154185022, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24641993, Length=402, Percent_Identity=29.1044776119403, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24641995, Length=402, Percent_Identity=29.1044776119403, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24651635, Length=464, Percent_Identity=27.5862068965517, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24651633, Length=464, Percent_Identity=27.5862068965517, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24667468, Length=421, Percent_Identity=23.2779097387173, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24668806, Length=425, Percent_Identity=25.1764705882353, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356285, Length=425, Percent_Identity=25.1764705882353, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24668802, Length=425, Percent_Identity=25.1764705882353, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221512776, Length=410, Percent_Identity=21.4634146341463, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666159, Length=410, Percent_Identity=21.4634146341463, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281366235, Length=408, Percent_Identity=25.9803921568627, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI116007820, Length=408, Percent_Identity=25.9803921568627, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI116007818, Length=408, Percent_Identity=25.9803921568627, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI85725152, Length=408, Percent_Identity=25.9803921568627, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161077963, Length=417, Percent_Identity=23.9808153477218, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49965; Mature: 49833

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTREGGLIKGLGLVDSTTLVMGSMIGSGVFIVAADISRQVQSPGLMMMTWFVTALLTL
CCCCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECHHHHHCCCCHHHHHHHHHHHHHH
IAALSYGELAAAMPHAGGQYVYLREAFGPLYGFLYGWTLFMVIQTGTIAAVAVAFAKYAG
HHHHCHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VFFPWISDQNYLLGAGKVGFTTQQLVAIAIIVFLTWSNTRGIRTGAMVQNIFTIAKVAAI
HEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LGLIAAGFLVGRNPEAIASNFNGFWRNSGWNFDTVRLVGVAMVGSLFSSDAWNNVTFTAG
HHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECC
EVRNPRRNLPLSLALGVCIVSALYILSNFVYLNVLTFDAIQHAPKDRVAALAAEHMLGPV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALQIMAAAIMISTFGCVNGLTLAGARVYYAMAKDRLFFRRATELDPKTNAPVFSLTVQCA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEE
WSVALTLSGSYNDLLDYVIFAVLLFYILTIAGLFVLRRTRPDMDRPYKAIGYPVLPAVYI
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHH
LAAGLIEVLLLAYKPNYTWPGLIIVLLGLPVYFIWRGKATI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEECCCCCC
>Mature Secondary Structure 
ATTREGGLIKGLGLVDSTTLVMGSMIGSGVFIVAADISRQVQSPGLMMMTWFVTALLTL
CCCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECHHHHHCCCCHHHHHHHHHHHHHH
IAALSYGELAAAMPHAGGQYVYLREAFGPLYGFLYGWTLFMVIQTGTIAAVAVAFAKYAG
HHHHCHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VFFPWISDQNYLLGAGKVGFTTQQLVAIAIIVFLTWSNTRGIRTGAMVQNIFTIAKVAAI
HEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LGLIAAGFLVGRNPEAIASNFNGFWRNSGWNFDTVRLVGVAMVGSLFSSDAWNNVTFTAG
HHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECC
EVRNPRRNLPLSLALGVCIVSALYILSNFVYLNVLTFDAIQHAPKDRVAALAAEHMLGPV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALQIMAAAIMISTFGCVNGLTLAGARVYYAMAKDRLFFRRATELDPKTNAPVFSLTVQCA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEE
WSVALTLSGSYNDLLDYVIFAVLLFYILTIAGLFVLRRTRPDMDRPYKAIGYPVLPAVYI
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHH
LAAGLIEVLLLAYKPNYTWPGLIIVLLGLPVYFIWRGKATI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]