Click here to switch to the map view.

The map label for this gene is soxB [H]

Identifier: 116624020

GI number: 116624020

Start: 6225643

End: 6226800

Strand: Reverse

Name: soxB [H]

Synonym: Acid_4932

Alternate gene names: 116624020

Gene position: 6226800-6225643 (Counterclockwise)

Preceding gene: 116624021

Following gene: 116624018

Centisome position: 62.48

GC content: 66.58

Gene sequence:

>1158_bases
ATGGCACGCGAATCTGCGTCGGTGGTGATTGTGGGGGCGGGGATTGTTGGCGCGTCGATTGCCTATCACCTCGCCGTGCG
GGGATGCACGGACGTGATCGTGCTGGAGAAGGCCGACCGCGAAGCGGCGGGAAGCACGGCGCGCTCGGCGGCGGGCGTGC
GGCATCAGTTCGCGAGCGACGTGAACATCCGGCTCTCTCTTTACAGCATCGAGCGATTGAAGCGGTTCGCCGAGGAAGTG
GGCGGGGAAGCGGGGCTGAAGCAGATCGGCTACCTGCTGCTGGTGTCGGAGCCCAACCGGTGGGAGGAATACCAGCGCAG
CGTCGCGCTGCAGAATTCACTGGGCGTGGCGAGCCGGGTGCTCTCCCCCGCCGAGGTGCGAGACCTGCTGCCCTACACCA
GGATCGATGGCCTGCTGGGGGCGACCTATTGCGCGGAGGACGGGCACTGCGATCCGCACGGAGTCGCAATGGGCTACCTG
GCAGCCGCGCGGCGGCTGGGTGTCGCGGTGCGTCGCGCGTCGGCCGCGACGGGCATGCAGCGCGCGGATGGCCGGGTAAT
CGCAGTCGAGACGGCGGCGGGGCCAATTGCATGCGAGGTGGTGATCAACGCGGCTGGTCCGTGGGCAGGGACCGTCGCTG
CGATGGCAGGGGTCGCGGTGCCGGTACTGCCTTACCGCCGGTGCATCTACCTTACGGAAGCGATGCCGGAAATGCCGGTT
ATTCCCTTCACTATCGACACCGGTAGCGGCTTCTACATGCGCAAGGAGGGAGACAAGCTGCTGCTCGGGGTGAGCAACGA
TCGTGAGCCCGCGGGCGAGAATCTGTCGGTGGATTGGGAGTGGATGGAAACCGTACTGGAGCGTGGAGCGGAGCGCTTTC
CATTCCTTGCGAATGTCGGGATCGTGCGCCGCAATTGTTGGGCCGGGTTGTACGAGATCACGCCCGACCACATGCCGGTG
CTGGGGCGGCGCGCCGAACTGCCGAACTACATTGATGCATCGGGCTTCAGCGGGCATGGCGTGATGCACGCGCCCGCCAC
GGGGATGTTGATCGCCGAGGAGGTGCTGGACGGGCGCGCGCACACTATCGCCATCGACGAACTCCGGGTGACGCGATTCG
CGCGGGCGGCGATGGGCGGGGAACGGAACGTCTACTAG

Upstream 100 bases:

>100_bases
GCCTTCGCAAGTGGCTGATCGCTCCTTGCGGTCGCGGCTCTGATCGGGGCGTCCGCTGCAAAGAGCACCGGCTCGTCGGC
ACGATGGCACAATAAACGGC

Downstream 100 bases:

>100_bases
CGGCCGATCACGACACCGACGGCGGCGGGCGCCACGTCGAGCCGGTCGATGCGGTGGCCGAGTTCGAAGGGCTTACCGAT
GACAGCGTCGGGGTACAAGG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MARESASVVIVGAGIVGASIAYHLAVRGCTDVIVLEKADREAAGSTARSAAGVRHQFASDVNIRLSLYSIERLKRFAEEV
GGEAGLKQIGYLLLVSEPNRWEEYQRSVALQNSLGVASRVLSPAEVRDLLPYTRIDGLLGATYCAEDGHCDPHGVAMGYL
AAARRLGVAVRRASAATGMQRADGRVIAVETAAGPIACEVVINAAGPWAGTVAAMAGVAVPVLPYRRCIYLTEAMPEMPV
IPFTIDTGSGFYMRKEGDKLLLGVSNDREPAGENLSVDWEWMETVLERGAERFPFLANVGIVRRNCWAGLYEITPDHMPV
LGRRAELPNYIDASGFSGHGVMHAPATGMLIAEEVLDGRAHTIAIDELRVTRFARAAMGGERNVY

Sequences:

>Translated_385_residues
MARESASVVIVGAGIVGASIAYHLAVRGCTDVIVLEKADREAAGSTARSAAGVRHQFASDVNIRLSLYSIERLKRFAEEV
GGEAGLKQIGYLLLVSEPNRWEEYQRSVALQNSLGVASRVLSPAEVRDLLPYTRIDGLLGATYCAEDGHCDPHGVAMGYL
AAARRLGVAVRRASAATGMQRADGRVIAVETAAGPIACEVVINAAGPWAGTVAAMAGVAVPVLPYRRCIYLTEAMPEMPV
IPFTIDTGSGFYMRKEGDKLLLGVSNDREPAGENLSVDWEWMETVLERGAERFPFLANVGIVRRNCWAGLYEITPDHMPV
LGRRAELPNYIDASGFSGHGVMHAPATGMLIAEEVLDGRAHTIAIDELRVTRFARAAMGGERNVY
>Mature_384_residues
ARESASVVIVGAGIVGASIAYHLAVRGCTDVIVLEKADREAAGSTARSAAGVRHQFASDVNIRLSLYSIERLKRFAEEVG
GEAGLKQIGYLLLVSEPNRWEEYQRSVALQNSLGVASRVLSPAEVRDLLPYTRIDGLLGATYCAEDGHCDPHGVAMGYLA
AARRLGVAVRRASAATGMQRADGRVIAVETAAGPIACEVVINAAGPWAGTVAAMAGVAVPVLPYRRCIYLTEAMPEMPVI
PFTIDTGSGFYMRKEGDKLLLGVSNDREPAGENLSVDWEWMETVLERGAERFPFLANVGIVRRNCWAGLYEITPDHMPVL
GRRAELPNYIDASGFSGHGVMHAPATGMLIAEEVLDGRAHTIAIDELRVTRFARAAMGGERNVY

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=370, Percent_Identity=32.4324324324324, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI21361378, Length=370, Percent_Identity=32.4324324324324, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI24797151, Length=395, Percent_Identity=29.1139240506329, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI8923708, Length=414, Percent_Identity=30.9178743961353, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI194306651, Length=388, Percent_Identity=28.0927835051546, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17541536, Length=427, Percent_Identity=26.6978922716628, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994045, Length=400, Percent_Identity=25, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994052, Length=407, Percent_Identity=24.3243243243243, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20130091, Length=368, Percent_Identity=29.3478260869565, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI20129729, Length=413, Percent_Identity=31.7191283292978, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571104, Length=385, Percent_Identity=28.8311688311688, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI17985989, Length=386, Percent_Identity=25.1295336787565, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41366; Mature: 41235

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARESASVVIVGAGIVGASIAYHLAVRGCTDVIVLEKADREAAGSTARSAAGVRHQFASD
CCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCC
VNIRLSLYSIERLKRFAEEVGGEAGLKQIGYLLLVSEPNRWEEYQRSVALQNSLGVASRV
CEEEEEEHHHHHHHHHHHHHCCCCCHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LSPAEVRDLLPYTRIDGLLGATYCAEDGHCDPHGVAMGYLAAARRLGVAVRRASAATGMQ
CCHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RADGRVIAVETAAGPIACEVVINAAGPWAGTVAAMAGVAVPVLPYRRCIYLTEAMPEMPV
HCCCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHEEHHHCCCCCCE
IPFTIDTGSGFYMRKEGDKLLLGVSNDREPAGENLSVDWEWMETVLERGAERFPFLANVG
EEEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHCCCHHCCC
IVRRNCWAGLYEITPDHMPVLGRRAELPNYIDASGFSGHGVMHAPATGMLIAEEVLDGRA
HHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCC
HTIAIDELRVTRFARAAMGGERNVY
EEEEEHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ARESASVVIVGAGIVGASIAYHLAVRGCTDVIVLEKADREAAGSTARSAAGVRHQFASD
CCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCC
VNIRLSLYSIERLKRFAEEVGGEAGLKQIGYLLLVSEPNRWEEYQRSVALQNSLGVASRV
CEEEEEEHHHHHHHHHHHHHCCCCCHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LSPAEVRDLLPYTRIDGLLGATYCAEDGHCDPHGVAMGYLAAARRLGVAVRRASAATGMQ
CCHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RADGRVIAVETAAGPIACEVVINAAGPWAGTVAAMAGVAVPVLPYRRCIYLTEAMPEMPV
HCCCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHEEHHHCCCCCCE
IPFTIDTGSGFYMRKEGDKLLLGVSNDREPAGENLSVDWEWMETVLERGAERFPFLANVG
EEEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHCCCHHCCC
IVRRNCWAGLYEITPDHMPVLGRRAELPNYIDASGFSGHGVMHAPATGMLIAEEVLDGRA
HHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCC
HTIAIDELRVTRFARAAMGGERNVY
EEEEEHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]