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The map label for this gene is steT [H]

Identifier: 116624002

GI number: 116624002

Start: 6201094

End: 6202434

Strand: Reverse

Name: steT [H]

Synonym: Acid_4914

Alternate gene names: 116624002

Gene position: 6202434-6201094 (Counterclockwise)

Preceding gene: 116624003

Following gene: 116624001

Centisome position: 62.24

GC content: 61.74

Gene sequence:

>1341_bases
ATGGCGGAAAAACAGATCGGCGACGAAGGGCTGGTGCGGGGCTTTGGCCTGCTCCATGCCACCGCGCTCAACATGAGCAA
CATGGTGGGCGTGGGACCGTTCATCACGATCCCGCTGATCATCGCCTCGATGGGCGGACCTCAATGCATGTTGGGCTGGC
TCTTGGGCGCCGTCCTCGCGCTTTGCGACGGGCTGGTCTGGAGCGAACTGGCGGCGGCGATGCCCGGGACCGGCGGCACC
TACCTCTACCTGCGCGAGGCCTTCCGCAAGACTCGCCTGGGCGGCATCCTCCCATTTCTCTTCATCTGGCAATTCATCAT
CAGCGGCCCTTTGGAAATCGCTTCCGGCTACATCGGCTTCGCGCAGTACGTCGGCTACTTCTGGCGCGGCATGGGTCCGT
GGGAGACCCGGCTGCTCAGCCTGTCTGTCGGAACAGTGGTAATCGTGCTGCTCTATCGCAGGGTGACGGCGGTGGCGAAG
ATGGCCGTAGTGCTGTGGATCGGCATGCTGGCGACGGTGCTGTGGATCGTGGTCAGCGGCCTCGCCAACTTCAATGCGCG
CGTGGTCTTCGATTTTCCTCCGGGCGCCTTCACTTTCTCGCGCGGTTTCCTGGCGGGGCTAGGCTCGGCGATGCTGATCG
CGATGTACGATTTCATGGGCTACTACGACATCTGCTACGTCGGCGGAGAAGTCCGCAATCCGGCACGCGTGATTCCGCGG
TCCATCATTTATTCGGTGCTCGCGGTGGCGGCGATCTACGCGCTGATGAATTTGAGCATCATCGCGGTGGTGCCGTGGCG
GGAAGCGATGAATTCGAAGTTCATCGCGGCGCAGTTCATTGAAAAGCTGTACGGCACTCGCGCAGCCGCCGTGGTGACGG
TGCTGGTGTTGTGGACGGCATTCGCATCGGTCTTCGCGCTGCTGCTCGGCTACAGCCGCATTCCTTATGCGGCGGCGGTC
AACGGAGATTTCTTCGCCGTCTTCGGCCGGCTGCACGCGACCGGAAAATTCCCGCACGTCTCGTTGCTCGTGATGGGCGC
GCTCTCGATTGTCGCGTCGCTGTGGAACCTGGACGCGGTGATTTCGGCGCTACTGACTTCGCGCATCCTGATTCAGTTCG
TCGCGCAGATCTTCGCATTGCACTATCTCCGCCGGCACCGCCACGATATCGAGCGGCCCTTTCGTGCATGGCTGTACCCT
TTGCCCAGCGTGATCGCATTCGCGGGCTGGGCCTACATCTTCCTGACATCGGGTTGGAACTTCGCGGGCTTCGGAGTCTT
GACGCTGGCTGCGGGGGTTGGTGCTTACTTGCTGTGGCGAAAGGTGACAAAATACTCCTGA

Upstream 100 bases:

>100_bases
GCGCTGATTGCGTGGCTGGCCGCGAACGCCACGCGCTAAAGAACCGCGACCGTCAAGGAGCGTTCTCCTAATTGATTTAC
CATGTACGCTGACGGCGTTC

Downstream 100 bases:

>100_bases
ATGCTCAAACTCATTGCTGCTTGTGCGCTGGCTGCATGCGCCGCACTTGCTCAAGATCTCGCCGCGCCGAGGCTCGTCAC
GCTGAATCTGACCGCGACCG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MAEKQIGDEGLVRGFGLLHATALNMSNMVGVGPFITIPLIIASMGGPQCMLGWLLGAVLALCDGLVWSELAAAMPGTGGT
YLYLREAFRKTRLGGILPFLFIWQFIISGPLEIASGYIGFAQYVGYFWRGMGPWETRLLSLSVGTVVIVLLYRRVTAVAK
MAVVLWIGMLATVLWIVVSGLANFNARVVFDFPPGAFTFSRGFLAGLGSAMLIAMYDFMGYYDICYVGGEVRNPARVIPR
SIIYSVLAVAAIYALMNLSIIAVVPWREAMNSKFIAAQFIEKLYGTRAAAVVTVLVLWTAFASVFALLLGYSRIPYAAAV
NGDFFAVFGRLHATGKFPHVSLLVMGALSIVASLWNLDAVISALLTSRILIQFVAQIFALHYLRRHRHDIERPFRAWLYP
LPSVIAFAGWAYIFLTSGWNFAGFGVLTLAAGVGAYLLWRKVTKYS

Sequences:

>Translated_446_residues
MAEKQIGDEGLVRGFGLLHATALNMSNMVGVGPFITIPLIIASMGGPQCMLGWLLGAVLALCDGLVWSELAAAMPGTGGT
YLYLREAFRKTRLGGILPFLFIWQFIISGPLEIASGYIGFAQYVGYFWRGMGPWETRLLSLSVGTVVIVLLYRRVTAVAK
MAVVLWIGMLATVLWIVVSGLANFNARVVFDFPPGAFTFSRGFLAGLGSAMLIAMYDFMGYYDICYVGGEVRNPARVIPR
SIIYSVLAVAAIYALMNLSIIAVVPWREAMNSKFIAAQFIEKLYGTRAAAVVTVLVLWTAFASVFALLLGYSRIPYAAAV
NGDFFAVFGRLHATGKFPHVSLLVMGALSIVASLWNLDAVISALLTSRILIQFVAQIFALHYLRRHRHDIERPFRAWLYP
LPSVIAFAGWAYIFLTSGWNFAGFGVLTLAAGVGAYLLWRKVTKYS
>Mature_445_residues
AEKQIGDEGLVRGFGLLHATALNMSNMVGVGPFITIPLIIASMGGPQCMLGWLLGAVLALCDGLVWSELAAAMPGTGGTY
LYLREAFRKTRLGGILPFLFIWQFIISGPLEIASGYIGFAQYVGYFWRGMGPWETRLLSLSVGTVVIVLLYRRVTAVAKM
AVVLWIGMLATVLWIVVSGLANFNARVVFDFPPGAFTFSRGFLAGLGSAMLIAMYDFMGYYDICYVGGEVRNPARVIPRS
IIYSVLAVAAIYALMNLSIIAVVPWREAMNSKFIAAQFIEKLYGTRAAAVVTVLVLWTAFASVFALLLGYSRIPYAAAVN
GDFFAVFGRLHATGKFPHVSLLVMGALSIVASLWNLDAVISALLTSRILIQFVAQIFALHYLRRHRHDIERPFRAWLYPL
PSVIAFAGWAYIFLTSGWNFAGFGVLTLAAGVGAYLLWRKVTKYS

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI7657683, Length=400, Percent_Identity=27.5, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI187423910, Length=414, Percent_Identity=24.1545893719807, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7657591, Length=414, Percent_Identity=24.1545893719807, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI33286428, Length=467, Percent_Identity=23.982869379015, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI186910308, Length=349, Percent_Identity=24.9283667621776, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI186910306, Length=349, Percent_Identity=24.9283667621776, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI186910304, Length=349, Percent_Identity=24.9283667621776, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI9790235, Length=312, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI115648063, Length=346, Percent_Identity=21.9653179190751, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI115648022, Length=346, Percent_Identity=21.9653179190751, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI71999149, Length=430, Percent_Identity=23.953488372093, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI110347453, Length=369, Percent_Identity=27.10027100271, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082250, Length=452, Percent_Identity=23.4513274336283, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32566699, Length=361, Percent_Identity=26.8698060941828, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540018, Length=416, Percent_Identity=22.5961538461538, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17568033, Length=447, Percent_Identity=24.1610738255034, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=418, Percent_Identity=25.5980861244019, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566695, Length=418, Percent_Identity=25.5980861244019, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993915, Length=373, Percent_Identity=24.1286863270777, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=402, Percent_Identity=25.6218905472637, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=402, Percent_Identity=25.6218905472637, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=377, Percent_Identity=23.342175066313, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71995388, Length=377, Percent_Identity=23.342175066313, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321492, Length=322, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357367, Length=460, Percent_Identity=25.8695652173913, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45550968, Length=404, Percent_Identity=25.4950495049505, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19921172, Length=404, Percent_Identity=25.4950495049505, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641993, Length=399, Percent_Identity=25.062656641604, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641995, Length=399, Percent_Identity=25.062656641604, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221331183, Length=401, Percent_Identity=24.9376558603491, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17647653, Length=401, Percent_Identity=24.9376558603491, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24664379, Length=401, Percent_Identity=24.9376558603491, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651635, Length=436, Percent_Identity=21.3302752293578, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24651633, Length=436, Percent_Identity=21.3302752293578, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24666159, Length=424, Percent_Identity=20.9905660377358, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221512776, Length=424, Percent_Identity=20.9905660377358, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24667468, Length=366, Percent_Identity=20.7650273224044, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48828; Mature: 48696

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEKQIGDEGLVRGFGLLHATALNMSNMVGVGPFITIPLIIASMGGPQCMLGWLLGAVLA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LCDGLVWSELAAAMPGTGGTYLYLREAFRKTRLGGILPFLFIWQFIISGPLEIASGYIGF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AQYVGYFWRGMGPWETRLLSLSVGTVVIVLLYRRVTAVAKMAVVLWIGMLATVLWIVVSG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANFNARVVFDFPPGAFTFSRGFLAGLGSAMLIAMYDFMGYYDICYVGGEVRNPARVIPR
HCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHH
SIIYSVLAVAAIYALMNLSIIAVVPWREAMNSKFIAAQFIEKLYGTRAAAVVTVLVLWTA
HHHHHHHHHHHHHHHHCCHHEEEECCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
FASVFALLLGYSRIPYAAAVNGDFFAVFGRLHATGKFPHVSLLVMGALSIVASLWNLDAV
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ISALLTSRILIQFVAQIFALHYLRRHRHDIERPFRAWLYPLPSVIAFAGWAYIFLTSGWN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCC
FAGFGVLTLAAGVGAYLLWRKVTKYS
CHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]