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The map label for this gene is degT [H]

Identifier: 116623951

GI number: 116623951

Start: 6141629

End: 6142882

Strand: Direct

Name: degT [H]

Synonym: Acid_4863

Alternate gene names: 116623951

Gene position: 6141629-6142882 (Clockwise)

Preceding gene: 116623950

Following gene: 116623952

Centisome position: 61.63

GC content: 64.75

Gene sequence:

>1254_bases
ATGCCACATTCGCGTTTGTACTCCATTCCCCGATTTGCATTGCCGTATACATCCGGCGATTTCGCCGCTGGATTGCGGGC
CGCTTTCAGCAGCACTCCGCCTCCCGATGGGTTCGGACTGCTTGGCGGCAGCCCGAAGTTCTGGACGCGAAGCGGACGGC
AGGCGCTCCGTCTTTTGCTGGGCGCGCTCGATCTGAAACCGAACTCCGGCGTAGCACTGCCCTTGTTTACAGATCCGTCG
CTGGTCAGGGCCATTGTGGCGGCGGGCCACCGGCCGGTCTTCATCGATGTGGATGCGCGGTTCCTGACGATGGACCCGGG
GTGCCTGGAAGACGCGCGCGGAATGTACTCCGCGGTGGTCGCCGTCCACCTGTTCGGACAGCTGGCGGACATGCCGGCGA
TCCTGGCCGCGTCCGGCGGGGCGCCCGTACTCGAGGATGCCGCGCACGCTCCGCTGAGTTATCTTCACGGGCGCATGGCC
GGCAGGTTCGGCGCCGCCGCGTTCTACAGCTTCGCCTCCACTAAGTATTGGCCGGCGGGCGGCGGCGGACTCGCCATCGT
GCATCATGCTAATATCGCGCGGCGACTCGCCGACAGCACACGAGTGCTCTCGCAGCCTTCCCGCGTCGAGGAATTGCGTG
GACTGGTTCTTCAGGCTGCCAAGGCGGTGATCTTCCAACGCCGGCTCTATGGATTCTTCGGCAAGCCGCTGCGCCGCTGG
ACCGATCGATTGGGCTTGCTGGAGCCGTGCCTGGACCTGAAAGCGATCCAGCGTCCGTGGGCGGCGGTGGCGTGCCGCCA
AGCGATGCGATTTTCGGAGCGAGTCGAGATGCAGCGGGCAAACAGCCTGCGCCTCCTGGCCCGGCTGGCCGGCTTGCCTG
ACGTAGTGTTGCCCAGGGAGCGGCCGGGAGCGCAGTACAACTATCATATCTTCCCGGTATTGCTGCACGACCGCGAGGAG
CGCGCCGCGGTAATGCGCTCCATGTGGTCGAGGTTCGTCGATACCTCCATGATCTACGCGGGGGTTGTCAGGGAATGCCG
GAAATTCGGCTACGAAGGCGGCTGCCCGGTAGCCGAGTCGATCGCCGATCGCCTGATCACGCTGCCAAACTACGCAGGGC
TCACCGGAGAGGACATCGACCAGATCGCCGAGGTCTTTCTTTCCGACCTGGTGGCATGGCGCGCGCGCGCGAGCCGCGGG
CTGAAGGGGGCGGAGACAGAATATGTTGGCGAACCGCTGAAGAGGTATACGTAG

Upstream 100 bases:

>100_bases
TGGTGGCCGCCGCGCGGCGCGTTCGAAGTAACAGCCAACAGCTCGAAACCATCGAAACCGTCCTCCAAGGAGCGCGCTCA
TCCGGGCGCAGACTAGCCTG

Downstream 100 bases:

>100_bases
CATGGCAAACGAATCTTACGATGTGCGCAGTGAGTTTGAAACCGGCGCATTCATAATGTCCCTGGACACGGAGCAGATTT
GGGGTTACGTGGACCAGATG

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MPHSRLYSIPRFALPYTSGDFAAGLRAAFSSTPPPDGFGLLGGSPKFWTRSGRQALRLLLGALDLKPNSGVALPLFTDPS
LVRAIVAAGHRPVFIDVDARFLTMDPGCLEDARGMYSAVVAVHLFGQLADMPAILAASGGAPVLEDAAHAPLSYLHGRMA
GRFGAAAFYSFASTKYWPAGGGGLAIVHHANIARRLADSTRVLSQPSRVEELRGLVLQAAKAVIFQRRLYGFFGKPLRRW
TDRLGLLEPCLDLKAIQRPWAAVACRQAMRFSERVEMQRANSLRLLARLAGLPDVVLPRERPGAQYNYHIFPVLLHDREE
RAAVMRSMWSRFVDTSMIYAGVVRECRKFGYEGGCPVAESIADRLITLPNYAGLTGEDIDQIAEVFLSDLVAWRARASRG
LKGAETEYVGEPLKRYT

Sequences:

>Translated_417_residues
MPHSRLYSIPRFALPYTSGDFAAGLRAAFSSTPPPDGFGLLGGSPKFWTRSGRQALRLLLGALDLKPNSGVALPLFTDPS
LVRAIVAAGHRPVFIDVDARFLTMDPGCLEDARGMYSAVVAVHLFGQLADMPAILAASGGAPVLEDAAHAPLSYLHGRMA
GRFGAAAFYSFASTKYWPAGGGGLAIVHHANIARRLADSTRVLSQPSRVEELRGLVLQAAKAVIFQRRLYGFFGKPLRRW
TDRLGLLEPCLDLKAIQRPWAAVACRQAMRFSERVEMQRANSLRLLARLAGLPDVVLPRERPGAQYNYHIFPVLLHDREE
RAAVMRSMWSRFVDTSMIYAGVVRECRKFGYEGGCPVAESIADRLITLPNYAGLTGEDIDQIAEVFLSDLVAWRARASRG
LKGAETEYVGEPLKRYT
>Mature_416_residues
PHSRLYSIPRFALPYTSGDFAAGLRAAFSSTPPPDGFGLLGGSPKFWTRSGRQALRLLLGALDLKPNSGVALPLFTDPSL
VRAIVAAGHRPVFIDVDARFLTMDPGCLEDARGMYSAVVAVHLFGQLADMPAILAASGGAPVLEDAAHAPLSYLHGRMAG
RFGAAAFYSFASTKYWPAGGGGLAIVHHANIARRLADSTRVLSQPSRVEELRGLVLQAAKAVIFQRRLYGFFGKPLRRWT
DRLGLLEPCLDLKAIQRPWAAVACRQAMRFSERVEMQRANSLRLLARLAGLPDVVLPRERPGAQYNYHIFPVLLHDREER
AAVMRSMWSRFVDTSMIYAGVVRECRKFGYEGGCPVAESIADRLITLPNYAGLTGEDIDQIAEVFLSDLVAWRARASRGL
KGAETEYVGEPLKRYT

Specific function: This membrane protein may function as a sensor protein and may transfer the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of the genes [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=294, Percent_Identity=27.5510204081633, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI145693159, Length=183, Percent_Identity=32.7868852459016, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 45740; Mature: 45609

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHSRLYSIPRFALPYTSGDFAAGLRAAFSSTPPPDGFGLLGGSPKFWTRSGRQALRLLL
CCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GALDLKPNSGVALPLFTDPSLVRAIVAAGHRPVFIDVDARFLTMDPGCLEDARGMYSAVV
HHHCCCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHH
AVHLFGQLADMPAILAASGGAPVLEDAAHAPLSYLHGRMAGRFGAAAFYSFASTKYWPAG
HHHHHHHHHCCCHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GGGLAIVHHANIARRLADSTRVLSQPSRVEELRGLVLQAAKAVIFQRRLYGFFGKPLRRW
CCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
TDRLGLLEPCLDLKAIQRPWAAVACRQAMRFSERVEMQRANSLRLLARLAGLPDVVLPRE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
RPGAQYNYHIFPVLLHDREERAAVMRSMWSRFVDTSMIYAGVVRECRKFGYEGGCPVAES
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IADRLITLPNYAGLTGEDIDQIAEVFLSDLVAWRARASRGLKGAETEYVGEPLKRYT
HHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHCC
>Mature Secondary Structure 
PHSRLYSIPRFALPYTSGDFAAGLRAAFSSTPPPDGFGLLGGSPKFWTRSGRQALRLLL
CCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GALDLKPNSGVALPLFTDPSLVRAIVAAGHRPVFIDVDARFLTMDPGCLEDARGMYSAVV
HHHCCCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHH
AVHLFGQLADMPAILAASGGAPVLEDAAHAPLSYLHGRMAGRFGAAAFYSFASTKYWPAG
HHHHHHHHHCCCHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GGGLAIVHHANIARRLADSTRVLSQPSRVEELRGLVLQAAKAVIFQRRLYGFFGKPLRRW
CCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
TDRLGLLEPCLDLKAIQRPWAAVACRQAMRFSERVEMQRANSLRLLARLAGLPDVVLPRE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
RPGAQYNYHIFPVLLHDREERAAVMRSMWSRFVDTSMIYAGVVRECRKFGYEGGCPVAES
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IADRLITLPNYAGLTGEDIDQIAEVFLSDLVAWRARASRGLKGAETEYVGEPLKRYT
HHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104607 [H]