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The map label for this gene is luxQ [H]

Identifier: 116623865

GI number: 116623865

Start: 6042703

End: 6046779

Strand: Direct

Name: luxQ [H]

Synonym: Acid_4777

Alternate gene names: 116623865

Gene position: 6042703-6046779 (Clockwise)

Preceding gene: 116623861

Following gene: 116623866

Centisome position: 60.64

GC content: 63.04

Gene sequence:

>4077_bases
ATGGCTTGGACCGGATGGGCCCGTCTTTGCACAGCACTGATCGTGTCTTGTGTCGCGCCGCGCCCCGCCCCGGCGGCCGA
AAGTTCAACGGGATCTCTACGCCTCGGTATCCGGACCCTGCCCCTAATCGATAAGCAGGACATCCGCTTCGTGCGGGTCG
CGGCGGAGGGGGAATCGCTCGAGAGCCGGGTCACGAGCATCGCCCAGGATCGATATGGTTTCCTGTGGTTCGGCAGTGAC
GATGGTTTGTACCGTTACGACGGATACAAGCTCAAGTCCTTCCGGCGCGAGCCAGGCAATCCCAATAGCCTGAGCGACGA
TACCGTAACGGCGATTTACCGGGACCGGACCGGCATTCTCTGGGTCGGCACTGGATTTGGCGGGCTGAACCGCTTCGACC
CCGCATCCGGCACGTTCACCCACTACCGGCACGACCCCTCCAATCGCGGAAGCTTGAGCAGCAACGCCGCCAGGTGCATC
TTCCAGGATGCGGCCGGCGCGCTGTGGGTGGGAACCGCTAACGGGCTCGACCGCCTCGACCAGACCACCGGAAGCTTCGC
TCACTATCAGCACAACAAGCAGGACGCAGGCAGCTTGAGCAGCAATGAGGCAGTCGATATCTTCGAAGACCGCTCGGGGA
ATCTGTGGGTCGGCACCATCGGCGGCGGCCTCAATATTCTGGACCGGAGCACCGGCCGCTTTACGCGCTTTCGTGAATCG
TATACTGCCGCCAGCCCGGGCGATGACAGCAGTGCCCTGCTCAGCAGCATCCGGCAGGACCACGCCGGTTTGCTGTGGGT
CGGCAACGGCCTCGGCACCCTGGATCCGCGCACCGGGACTCTGACGCGATACGCGTTTCGTTCGAAAGATCCCGGCGGCG
AAATCATCAAAGGACTGAGAGCTCTCCAGGAAGGCCGCGAAGGTGAGCTCTGGCTGGGCATGCAGAACGGGTTGCTCCTG
CTCGACCGCGAGCGCAAGCAGTTCGCCCGCTATCTCAAGAAGCCGGCCAATCCCCAGAGCCTGCACAATGACGACATCCT
GAGCCTGTTCCAGGATGCCGAGGGAAATATCTGGGTGGGCACCCAGAGCGGAGTGAGCCGGTTCAACCCCAGACCGCTAT
TCACCATTCGTCAGCACGAGCCCGGCAATTCCCAGAGTTTGGTGGAAAACAATATTCGCGCCGTGCAGGTGGATAGGCAG
GGCAACCTCTGGGTCGGCACGCGCCGCGGCCTGCAGCGATTCGAGCCGAAGACCGGCCGTGCCACCCTTTACCAGCACGA
TCCTCACGATCCCAGCAGCATCTCGAACAACTATGTGACCGTTATCCGGGAAGATCGCTCCGGCGTGCTCTGGGTCGGCA
CGGGAGGCGGAGGACTGAACCGGTTCGACGGCACAAGAGGACGCTTCTTCGCCTACCGCTACCAACCGGGCAACCCCGCG
GGCCTGAGTAGCGACGGAGTCCTCTCGCTTCTGGAAGACCGCGAAGGAATGCTCTGGGTGGCTACCGCCGCGGGCCTGAG
CCGCCTCAACCGCCGAACCGGGCGCTTCACGACGTACCACCACGACGACAGCGATCCGCACAGCCTGTCCGACGACCTCA
TCAAGACCGTGTTCGAAGATCGGGACGGTACCCTGTGGGTGGGAACCAAAGGGGGCCTTAACCGTTTCGACCGCGCGTCG
CAGCACTTCACATCCTGGCAGCACAACGCTCACGACGCCTCGAGCCTGAGCCACGACCAGGTCAATGCGATCTCGGAAGA
CCGGAAGGGACGGCTGTGGTTGGCGACCCAGGAGGGACTCGACCAGATGGACCGCAGCCGTGGGACCTTCACCACCTTCA
CGCGCGAGGATGGTCTCCCCGATAACGCCGTGCAGTCCATTCTGGAAGACGATCACGGGTCTCTATGGCTGGCCACCCAT
AACGGCCTGGCGAGATTCCGTCCTGCCTCCGGGACCTTTCGCAACTACTCCGCCGCCGATGGCCTGCCCGGCAATCTGTT
GAACCCGCTCGGCACCGAAAGCAGTTGCCGCGGTCCGGACGGGCAATTGTGGTTCGGCTCCCGCAACGGACTGGTATCCT
TCTACCCCGACCGGCTGGCCGACAATCCTTACGTTCCGCCAGTGACATTGACGGACTTCCGCCTGTTCAACAAGACTGTG
CACCCGGGCCCAAACTCGCCGCTCCAACAGCCAATCTGGGCAACCCGTTCGTTGACGCTGACCCAGGCGCAAGGCATCTT
CTCGCTGGAGTTTGCCGCCTTGAGCAATACCGCGCCGGAGAGCAATCGCTACCGTTTCATGCTGGAGGGGCTGGAGACAG
AGTGGAACGAGGTGAGCAGCCGGCAGCGGCTGGCGACGTACACAAATCTTCCCGCGGGGAATTACGTTTTCCGGGTGCAG
GGCTCCAACAACAATCAGGTTTGGAATCAAGAGGGCGTCAGCCTCGCCATCGTCGTTCTGGCGCCCTGGTGGGCGACCTG
GTGGTTCCGAAGCACGGTGGGTTTGGTGATTGCGGGCATGGCGTTCGGAGCCTATCAATCCCGCGTGAGGATTCTGCGGC
TGGGAGCCGCGCGGCTCGAGAGGCAGGTGTCGGAGCGAACCAGCGAACTCCTGGAGCGAACCGGCGAGCTGCAAATCGCA
AAAGATGCGGCGGAGGCTGCCAATCGCGCCAAGACCATCTTCCTGGCGAATATGAGCCACGAGCTGCGTACACCCCTGAA
TGCGATTCTCGGATTCTCCAACCTTCTGCGGGAAGGCGATGTTTCCGAATGGCAGCGCAATGACCTGGATATCATCAACC
GGAGCGGCGAACACTTACTCAGCCTGGTTGATGAGGTGCTGGACGTAGCCAAAATCGAGGCAGGCCGCGGCGTATTGGAG
ATCGCTCCCTACGACTTGGCCGGCATGGTGCGGGACGTGATGGATATGATGGGCGCGCGCGCGCAGATGAAGGGTCTTGC
GCTGCTCCATGCCGATTCTTCCGGGCTGCCTCGCTACGTGAGGGCGGATGGCCCCAGGCTCCGGCAAGTGTTGATCAACC
TGGTAGGCAATGCGATCAAGTTCACGCCCTCGGGCTCGGTCACGCTGAGGCTGGATGCCGGGTGCGTCGATGACGACGGA
CGATTCTCGTTGACGTTCTACGTGGAAGACACGGGCTGCGGCGTCGCGCCGGAGGATCACGAGCGAATCTTCGAGCCCTT
CGTGCAGGTAGGTCCGGCGGCGACGAAGAAAGGCAGCGGGCTCGGGCTCGCCATCACCAGGCAGTTGGTGGAAATGATGG
GGGGAACGGTGAGCGTGGAGAGCACGCCGGGGAAAGGGTCAAGGTTCCGGGTAGAGGTGCCGGTATACGCGCATGAGGAC
GCCGGTCCCCTCGGGGAGCGCACGGAGCGCGGACGGATTACCGGCCTGGAGCCGGGCCAGCCCGAATTCCGCGTCCTGGT
CTGCGAAGACGAGCCGACCAGCGCGGCGGTACTGCTGCGTTTCCTGCAATCCGCCGGTTTTCAGGTGAAAGTTGCCGACA
ACGGCGCCAAGGGAGTGGACCTGTTTCAAACCTGGCGGCCGGATTTCATCTGGATGGATCTGCGCATGCCGGTCATGAAC
GGGGCGGAGGCGGCGAAGCGCATTCGCGCTGTCGAGGGTGGGCGTGCCGTCAAGATCGCGGGCGTGAGCGCGTCGGCCTT
CGCCGAAGAGCGCAGTGAGGTACTCGCAGCCGGCATGGACGATTTCGTCCGCAAGCCTTTTCGGGCCGCCGAGATTTTCG
ACTGCATGGCACGACACCTCGGCGTGCGGTATTGTCGCAGCGAGTCCCAGCCATGCACGCGGCAGGAATCTCCGCCGCCG
CTCAGGGCGGAAGCGTTGGCAGGTCTTCCGCAAGAGCTGCGCGCGGAACTACAAGACGCGTTAGCTGCGCTCGACGTGGA
GCGGATTTCTGCAGTGGTGGTTCGCGTGACGGAGCGGGATTTCGGGCTCGGCTCGACGTTGTCACACTACGCCGACCGGC
TGGAATATACGGCAATCTTCCAGGCGATAGAGAACTGCCAGGCACCGGAGGTGTTCGCGAAGGGATCGACGGAATGA

Upstream 100 bases:

>100_bases
ACGCGGCCTGCTCCGGCAGCGCCGTAGGAAAAATAATGAATCCAGAGGCCGCTCGAGACATCACGTCCAATTGCTCCGAC
TATAGAGGTTTTTCGGAATT

Downstream 100 bases:

>100_bases
GCAACACCATGATCATGACGAGATTCGCATGGGCGTTCATTTATGCCGCTAACGCGCTCGCGGGTGACATCGTCATTCAT
CTGGATGACGCCGCAATTCC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1358; Mature: 1357

Protein sequence:

>1358_residues
MAWTGWARLCTALIVSCVAPRPAPAAESSTGSLRLGIRTLPLIDKQDIRFVRVAAEGESLESRVTSIAQDRYGFLWFGSD
DGLYRYDGYKLKSFRREPGNPNSLSDDTVTAIYRDRTGILWVGTGFGGLNRFDPASGTFTHYRHDPSNRGSLSSNAARCI
FQDAAGALWVGTANGLDRLDQTTGSFAHYQHNKQDAGSLSSNEAVDIFEDRSGNLWVGTIGGGLNILDRSTGRFTRFRES
YTAASPGDDSSALLSSIRQDHAGLLWVGNGLGTLDPRTGTLTRYAFRSKDPGGEIIKGLRALQEGREGELWLGMQNGLLL
LDRERKQFARYLKKPANPQSLHNDDILSLFQDAEGNIWVGTQSGVSRFNPRPLFTIRQHEPGNSQSLVENNIRAVQVDRQ
GNLWVGTRRGLQRFEPKTGRATLYQHDPHDPSSISNNYVTVIREDRSGVLWVGTGGGGLNRFDGTRGRFFAYRYQPGNPA
GLSSDGVLSLLEDREGMLWVATAAGLSRLNRRTGRFTTYHHDDSDPHSLSDDLIKTVFEDRDGTLWVGTKGGLNRFDRAS
QHFTSWQHNAHDASSLSHDQVNAISEDRKGRLWLATQEGLDQMDRSRGTFTTFTREDGLPDNAVQSILEDDHGSLWLATH
NGLARFRPASGTFRNYSAADGLPGNLLNPLGTESSCRGPDGQLWFGSRNGLVSFYPDRLADNPYVPPVTLTDFRLFNKTV
HPGPNSPLQQPIWATRSLTLTQAQGIFSLEFAALSNTAPESNRYRFMLEGLETEWNEVSSRQRLATYTNLPAGNYVFRVQ
GSNNNQVWNQEGVSLAIVVLAPWWATWWFRSTVGLVIAGMAFGAYQSRVRILRLGAARLERQVSERTSELLERTGELQIA
KDAAEAANRAKTIFLANMSHELRTPLNAILGFSNLLREGDVSEWQRNDLDIINRSGEHLLSLVDEVLDVAKIEAGRGVLE
IAPYDLAGMVRDVMDMMGARAQMKGLALLHADSSGLPRYVRADGPRLRQVLINLVGNAIKFTPSGSVTLRLDAGCVDDDG
RFSLTFYVEDTGCGVAPEDHERIFEPFVQVGPAATKKGSGLGLAITRQLVEMMGGTVSVESTPGKGSRFRVEVPVYAHED
AGPLGERTERGRITGLEPGQPEFRVLVCEDEPTSAAVLLRFLQSAGFQVKVADNGAKGVDLFQTWRPDFIWMDLRMPVMN
GAEAAKRIRAVEGGRAVKIAGVSASAFAEERSEVLAAGMDDFVRKPFRAAEIFDCMARHLGVRYCRSESQPCTRQESPPP
LRAEALAGLPQELRAELQDALAALDVERISAVVVRVTERDFGLGSTLSHYADRLEYTAIFQAIENCQAPEVFAKGSTE

Sequences:

>Translated_1358_residues
MAWTGWARLCTALIVSCVAPRPAPAAESSTGSLRLGIRTLPLIDKQDIRFVRVAAEGESLESRVTSIAQDRYGFLWFGSD
DGLYRYDGYKLKSFRREPGNPNSLSDDTVTAIYRDRTGILWVGTGFGGLNRFDPASGTFTHYRHDPSNRGSLSSNAARCI
FQDAAGALWVGTANGLDRLDQTTGSFAHYQHNKQDAGSLSSNEAVDIFEDRSGNLWVGTIGGGLNILDRSTGRFTRFRES
YTAASPGDDSSALLSSIRQDHAGLLWVGNGLGTLDPRTGTLTRYAFRSKDPGGEIIKGLRALQEGREGELWLGMQNGLLL
LDRERKQFARYLKKPANPQSLHNDDILSLFQDAEGNIWVGTQSGVSRFNPRPLFTIRQHEPGNSQSLVENNIRAVQVDRQ
GNLWVGTRRGLQRFEPKTGRATLYQHDPHDPSSISNNYVTVIREDRSGVLWVGTGGGGLNRFDGTRGRFFAYRYQPGNPA
GLSSDGVLSLLEDREGMLWVATAAGLSRLNRRTGRFTTYHHDDSDPHSLSDDLIKTVFEDRDGTLWVGTKGGLNRFDRAS
QHFTSWQHNAHDASSLSHDQVNAISEDRKGRLWLATQEGLDQMDRSRGTFTTFTREDGLPDNAVQSILEDDHGSLWLATH
NGLARFRPASGTFRNYSAADGLPGNLLNPLGTESSCRGPDGQLWFGSRNGLVSFYPDRLADNPYVPPVTLTDFRLFNKTV
HPGPNSPLQQPIWATRSLTLTQAQGIFSLEFAALSNTAPESNRYRFMLEGLETEWNEVSSRQRLATYTNLPAGNYVFRVQ
GSNNNQVWNQEGVSLAIVVLAPWWATWWFRSTVGLVIAGMAFGAYQSRVRILRLGAARLERQVSERTSELLERTGELQIA
KDAAEAANRAKTIFLANMSHELRTPLNAILGFSNLLREGDVSEWQRNDLDIINRSGEHLLSLVDEVLDVAKIEAGRGVLE
IAPYDLAGMVRDVMDMMGARAQMKGLALLHADSSGLPRYVRADGPRLRQVLINLVGNAIKFTPSGSVTLRLDAGCVDDDG
RFSLTFYVEDTGCGVAPEDHERIFEPFVQVGPAATKKGSGLGLAITRQLVEMMGGTVSVESTPGKGSRFRVEVPVYAHED
AGPLGERTERGRITGLEPGQPEFRVLVCEDEPTSAAVLLRFLQSAGFQVKVADNGAKGVDLFQTWRPDFIWMDLRMPVMN
GAEAAKRIRAVEGGRAVKIAGVSASAFAEERSEVLAAGMDDFVRKPFRAAEIFDCMARHLGVRYCRSESQPCTRQESPPP
LRAEALAGLPQELRAELQDALAALDVERISAVVVRVTERDFGLGSTLSHYADRLEYTAIFQAIENCQAPEVFAKGSTE
>Mature_1357_residues
AWTGWARLCTALIVSCVAPRPAPAAESSTGSLRLGIRTLPLIDKQDIRFVRVAAEGESLESRVTSIAQDRYGFLWFGSDD
GLYRYDGYKLKSFRREPGNPNSLSDDTVTAIYRDRTGILWVGTGFGGLNRFDPASGTFTHYRHDPSNRGSLSSNAARCIF
QDAAGALWVGTANGLDRLDQTTGSFAHYQHNKQDAGSLSSNEAVDIFEDRSGNLWVGTIGGGLNILDRSTGRFTRFRESY
TAASPGDDSSALLSSIRQDHAGLLWVGNGLGTLDPRTGTLTRYAFRSKDPGGEIIKGLRALQEGREGELWLGMQNGLLLL
DRERKQFARYLKKPANPQSLHNDDILSLFQDAEGNIWVGTQSGVSRFNPRPLFTIRQHEPGNSQSLVENNIRAVQVDRQG
NLWVGTRRGLQRFEPKTGRATLYQHDPHDPSSISNNYVTVIREDRSGVLWVGTGGGGLNRFDGTRGRFFAYRYQPGNPAG
LSSDGVLSLLEDREGMLWVATAAGLSRLNRRTGRFTTYHHDDSDPHSLSDDLIKTVFEDRDGTLWVGTKGGLNRFDRASQ
HFTSWQHNAHDASSLSHDQVNAISEDRKGRLWLATQEGLDQMDRSRGTFTTFTREDGLPDNAVQSILEDDHGSLWLATHN
GLARFRPASGTFRNYSAADGLPGNLLNPLGTESSCRGPDGQLWFGSRNGLVSFYPDRLADNPYVPPVTLTDFRLFNKTVH
PGPNSPLQQPIWATRSLTLTQAQGIFSLEFAALSNTAPESNRYRFMLEGLETEWNEVSSRQRLATYTNLPAGNYVFRVQG
SNNNQVWNQEGVSLAIVVLAPWWATWWFRSTVGLVIAGMAFGAYQSRVRILRLGAARLERQVSERTSELLERTGELQIAK
DAAEAANRAKTIFLANMSHELRTPLNAILGFSNLLREGDVSEWQRNDLDIINRSGEHLLSLVDEVLDVAKIEAGRGVLEI
APYDLAGMVRDVMDMMGARAQMKGLALLHADSSGLPRYVRADGPRLRQVLINLVGNAIKFTPSGSVTLRLDAGCVDDDGR
FSLTFYVEDTGCGVAPEDHERIFEPFVQVGPAATKKGSGLGLAITRQLVEMMGGTVSVESTPGKGSRFRVEVPVYAHEDA
GPLGERTERGRITGLEPGQPEFRVLVCEDEPTSAAVLLRFLQSAGFQVKVADNGAKGVDLFQTWRPDFIWMDLRMPVMNG
AEAAKRIRAVEGGRAVKIAGVSASAFAEERSEVLAAGMDDFVRKPFRAAEIFDCMARHLGVRYCRSESQPCTRQESPPPL
RAEALAGLPQELRAELQDALAALDVERISAVVVRVTERDFGLGSTLSHYADRLEYTAIFQAIENCQAPEVFAKGSTE

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=442, Percent_Identity=31.447963800905, Blast_Score=202, Evalue=1e-52,
Organism=Escherichia coli, GI87081816, Length=435, Percent_Identity=31.264367816092, Blast_Score=193, Evalue=6e-50,
Organism=Escherichia coli, GI48994928, Length=417, Percent_Identity=31.6546762589928, Blast_Score=189, Evalue=1e-48,
Organism=Escherichia coli, GI1789149, Length=285, Percent_Identity=35.7894736842105, Blast_Score=181, Evalue=3e-46,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=38.1526104417671, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI1786600, Length=244, Percent_Identity=34.0163934426229, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=29.5719844357977, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=31.304347826087, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=32.3275862068966, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=28.5067873303167, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=272, Percent_Identity=28.3088235294118, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=237, Percent_Identity=31.2236286919831, Blast_Score=84, Evalue=7e-17,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=29.8245614035088, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=29.1845493562232, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=24.3589743589744, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1789808, Length=226, Percent_Identity=26.1061946902655, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=32.8, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1786784, Length=111, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788545, Length=243, Percent_Identity=24.2798353909465, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789403, Length=317, Percent_Identity=26.4984227129338, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=166, Percent_Identity=40.9638554216867, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322000, Length=163, Percent_Identity=26.3803680981595, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 149630; Mature: 149499

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWTGWARLCTALIVSCVAPRPAPAAESSTGSLRLGIRTLPLIDKQDIRFVRVAAEGESL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCHH
ESRVTSIAQDRYGFLWFGSDDGLYRYDGYKLKSFRREPGNPNSLSDDTVTAIYRDRTGIL
HHHHHHHHHCCCEEEEECCCCCEEEECCEEEHHHCCCCCCCCCCCCCCEEEEEECCCCEE
WVGTGFGGLNRFDPASGTFTHYRHDPSNRGSLSSNAARCIFQDAAGALWVGTANGLDRLD
EEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHH
QTTGSFAHYQHNKQDAGSLSSNEAVDIFEDRSGNLWVGTIGGGLNILDRSTGRFTRFRES
HCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEECCCCHHHHHHHH
YTAASPGDDSSALLSSIRQDHAGLLWVGNGLGTLDPRTGTLTRYAFRSKDPGGEIIKGLR
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
ALQEGREGELWLGMQNGLLLLDRERKQFARYLKKPANPQSLHNDDILSLFQDAEGNIWVG
HHHCCCCCCEEEEECCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEE
TQSGVSRFNPRPLFTIRQHEPGNSQSLVENNIRAVQVDRQGNLWVGTRRGLQRFEPKTGR
CHHCHHHCCCCCEEEEECCCCCCCHHHHHCCCEEEEEECCCCEEEECHHHHHHCCCCCCC
ATLYQHDPHDPSSISNNYVTVIREDRSGVLWVGTGGGGLNRFDGTRGRFFAYRYQPGNPA
EEEEECCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCC
GLSSDGVLSLLEDREGMLWVATAAGLSRLNRRTGRFTTYHHDDSDPHSLSDDLIKTVFED
CCCCCCHHHHHHCCCCEEEEEEHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHC
RDGTLWVGTKGGLNRFDRASQHFTSWQHNAHDASSLSHDQVNAISEDRKGRLWLATQEGL
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHCCCCCCEEEEEHHHH
DQMDRSRGTFTTFTREDGLPDNAVQSILEDDHGSLWLATHNGLARFRPASGTFRNYSAAD
HHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCCCC
GLPGNLLNPLGTESSCRGPDGQLWFGSRNGLVSFYPDRLADNPYVPPVTLTDFRLFNKTV
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCCEEEHHHHHHCCCC
HPGPNSPLQQPIWATRSLTLTQAQGIFSLEFAALSNTAPESNRYRFMLEGLETEWNEVSS
CCCCCCCCCCCHHHHCEEEEECCCCEEEEEEHHHCCCCCCCCCEEEEEECCCCHHHHHHH
RQRLATYTNLPAGNYVFRVQGSNNNQVWNQEGVSLAIVVLAPWWATWWFRSTVGLVIAGM
HHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
AFGAYQSRVRILRLGAARLERQVSERTSELLERTGELQIAKDAAEAANRAKTIFLANMSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCEEEEEECCCH
ELRTPLNAILGFSNLLREGDVSEWQRNDLDIINRSGEHLLSLVDEVLDVAKIEAGRGVLE
HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEE
IAPYDLAGMVRDVMDMMGARAQMKGLALLHADSSGLPRYVRADGPRLRQVLINLVGNAIK
ECCCHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCEE
FTPSGSVTLRLDAGCVDDDGRFSLTFYVEDTGCGVAPEDHERIFEPFVQVGPAATKKGSG
ECCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
LGLAITRQLVEMMGGTVSVESTPGKGSRFRVEVPVYAHEDAGPLGERTERGRITGLEPGQ
CHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
PEFRVLVCEDEPTSAAVLLRFLQSAGFQVKVADNGAKGVDLFQTWRPDFIWMDLRMPVMN
CCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCCEEEEEEECCCCC
GAEAAKRIRAVEGGRAVKIAGVSASAFAEERSEVLAAGMDDFVRKPFRAAEIFDCMARHL
CHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHH
GVRYCRSESQPCTRQESPPPLRAEALAGLPQELRAELQDALAALDVERISAVVVRVTERD
HHHHHCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
FGLGSTLSHYADRLEYTAIFQAIENCQAPEVFAKGSTE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWTGWARLCTALIVSCVAPRPAPAAESSTGSLRLGIRTLPLIDKQDIRFVRVAAEGESL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCHH
ESRVTSIAQDRYGFLWFGSDDGLYRYDGYKLKSFRREPGNPNSLSDDTVTAIYRDRTGIL
HHHHHHHHHCCCEEEEECCCCCEEEECCEEEHHHCCCCCCCCCCCCCCEEEEEECCCCEE
WVGTGFGGLNRFDPASGTFTHYRHDPSNRGSLSSNAARCIFQDAAGALWVGTANGLDRLD
EEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHH
QTTGSFAHYQHNKQDAGSLSSNEAVDIFEDRSGNLWVGTIGGGLNILDRSTGRFTRFRES
HCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEECCCCHHHHHHHH
YTAASPGDDSSALLSSIRQDHAGLLWVGNGLGTLDPRTGTLTRYAFRSKDPGGEIIKGLR
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
ALQEGREGELWLGMQNGLLLLDRERKQFARYLKKPANPQSLHNDDILSLFQDAEGNIWVG
HHHCCCCCCEEEEECCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEE
TQSGVSRFNPRPLFTIRQHEPGNSQSLVENNIRAVQVDRQGNLWVGTRRGLQRFEPKTGR
CHHCHHHCCCCCEEEEECCCCCCCHHHHHCCCEEEEEECCCCEEEECHHHHHHCCCCCCC
ATLYQHDPHDPSSISNNYVTVIREDRSGVLWVGTGGGGLNRFDGTRGRFFAYRYQPGNPA
EEEEECCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCC
GLSSDGVLSLLEDREGMLWVATAAGLSRLNRRTGRFTTYHHDDSDPHSLSDDLIKTVFED
CCCCCCHHHHHHCCCCEEEEEEHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHC
RDGTLWVGTKGGLNRFDRASQHFTSWQHNAHDASSLSHDQVNAISEDRKGRLWLATQEGL
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHCCCCCCEEEEEHHHH
DQMDRSRGTFTTFTREDGLPDNAVQSILEDDHGSLWLATHNGLARFRPASGTFRNYSAAD
HHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCCCC
GLPGNLLNPLGTESSCRGPDGQLWFGSRNGLVSFYPDRLADNPYVPPVTLTDFRLFNKTV
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCCEEEHHHHHHCCCC
HPGPNSPLQQPIWATRSLTLTQAQGIFSLEFAALSNTAPESNRYRFMLEGLETEWNEVSS
CCCCCCCCCCCHHHHCEEEEECCCCEEEEEEHHHCCCCCCCCCEEEEEECCCCHHHHHHH
RQRLATYTNLPAGNYVFRVQGSNNNQVWNQEGVSLAIVVLAPWWATWWFRSTVGLVIAGM
HHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
AFGAYQSRVRILRLGAARLERQVSERTSELLERTGELQIAKDAAEAANRAKTIFLANMSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCEEEEEECCCH
ELRTPLNAILGFSNLLREGDVSEWQRNDLDIINRSGEHLLSLVDEVLDVAKIEAGRGVLE
HHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEE
IAPYDLAGMVRDVMDMMGARAQMKGLALLHADSSGLPRYVRADGPRLRQVLINLVGNAIK
ECCCHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCEE
FTPSGSVTLRLDAGCVDDDGRFSLTFYVEDTGCGVAPEDHERIFEPFVQVGPAATKKGSG
ECCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
LGLAITRQLVEMMGGTVSVESTPGKGSRFRVEVPVYAHEDAGPLGERTERGRITGLEPGQ
CHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
PEFRVLVCEDEPTSAAVLLRFLQSAGFQVKVADNGAKGVDLFQTWRPDFIWMDLRMPVMN
CCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCCEEEEEEECCCCC
GAEAAKRIRAVEGGRAVKIAGVSASAFAEERSEVLAAGMDDFVRKPFRAAEIFDCMARHL
CHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHH
GVRYCRSESQPCTRQESPPPLRAEALAGLPQELRAELQDALAALDVERISAVVVRVTERD
HHHHHCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
FGLGSTLSHYADRLEYTAIFQAIENCQAPEVFAKGSTE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]