Click here to switch to the map view.

The map label for this gene is yjjL [H]

Identifier: 116623854

GI number: 116623854

Start: 6027761

End: 6029137

Strand: Direct

Name: yjjL [H]

Synonym: Acid_4766

Alternate gene names: 116623854

Gene position: 6027761-6029137 (Clockwise)

Preceding gene: 116623850

Following gene: 116623855

Centisome position: 60.49

GC content: 62.67

Gene sequence:

>1377_bases
ATGTCACCCGATGGAACGGGGACCAACACATCAATCCGCGCGCTGATACAATTCTCGACTGTGAGCGCAACCTCAGTGAA
AACCAGCGCCGACCCGGACGCAATCAGACCGTCGGCGCGAATCGTTTCGATCCAGCGTTGGTCGATCGTGCTGCTGGTTG
GCGGGGGCGCGCTGAACTACGTGGATCGCGCAACGCTCTCCGTGGCCAACAAACTGATACAGGAAGACCTGGGAATTCCG
GTGGTCCGGATGGGGCTGCTGCTATCGGCCTTTCTGTGGGCGTATGCAATTGCGCAGCTTCCGGTTGGCGGGCTGATCGA
CCGGTATGGTCCGCGCCGCCTGCTTGGGTTGGGACTCTTCGGGTGGTCGCTGGCACAGGCGGCGGGCGGCCTCGTGACAA
GTTTCGGGCCTTTCATCGCGGCGCGATTCGCGTTGGGAGTCGGCGAGGCGCCGTTGTTTCCCGGAGGCGCGCGGGTAGTG
CGCGACTGGTTCGGGATTCGCGAACGGGGATTCGCCACCGGACTGCTGCAATCCGCCTCGTCCCTGGGCAACTTCATCGC
GGTCCCGCTGCTGACTTTTCTCATGCTGAGGTTGAGCTGGCGGTGGATGTTCGTGATCGTCGGGACGGCAGGGGTGTTTC
TGGCCGCGATCTGGTGGGCCATTCACCGCGATCCAGCGGAGGTTCGGCTTACCGGCGAGGAGGTTCGCTACCTGACCGAG
GGCGACGAGAATACCACTACGCGTCCGCCATCGTTCGCACAATGGAGGCAGCTATTCGCGCACAGGACCACGTGGGGCAT
GATCGCAGGCTTCTTCGGCACGATCTATACGCTTTGGATGTATACCGGCTGGCTGCCGTTCTATTTGGAGCACGAACGGC
ACATGAGCGTCGCGCGCGTTGGAATCGTGGCGGCAATTCCATACTTCTTCGGATGCGTCGGCGCGGTGTTGGGCGGGTGG
CTGTGTGATTTTCTGACGCGGCGCGGATGGGCGCCGATCGCGGGGCGGAAATTGCTGATCTCCTGCGCTCTTCTCGGGAT
ATCGGCGTGCACGCTGGGAACGGCATTTGCGGAATCCAACGCGATGGCGCTGACCTTCATTTCGATTTCGCTGTTCCTGA
TCTATATCGCGAGCAGTGCCGCATGGGCGACCGTTCCGATCGCCGCGCCGAGTCAATATACCGCCTCATTGGGCTCGATA
CAGAATTTCGGCGGGTACCTGGGAGGAGCGCTGGCGCCGACGGTGACGGGCCTGATTCTGCAACGCACCGGGAGCTTTTC
GCAGGCCCTGCTGTTGAGCGCCGGACTCAGCGCGCTTTCGGCGGTGGCGTACCTGCTGCTGGTCCGCAGCCCGATCCGGA
CCGATTCCGCGGCATAA

Upstream 100 bases:

>100_bases
CAGGCAGGCCGGCGTGAGGGACCTCTTCCACACCCTCCAGACTGAGTGCGATCTTCCGAAAATCCGCTGGCGTCATCGCA
CGCCTCCTATTTCACTGAGT

Downstream 100 bases:

>100_bases
AGCAAGCACCACCACGACTGGTGTAGAATTCCTGCATGCAACCTGCTTGGTTCCGCGCGGCCGCCGTTGGCGTCTCCGCC
TTCCTGTTGATCGCCGCCTA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSPDGTGTNTSIRALIQFSTVSATSVKTSADPDAIRPSARIVSIQRWSIVLLVGGGALNYVDRATLSVANKLIQEDLGIP
VVRMGLLLSAFLWAYAIAQLPVGGLIDRYGPRRLLGLGLFGWSLAQAAGGLVTSFGPFIAARFALGVGEAPLFPGGARVV
RDWFGIRERGFATGLLQSASSLGNFIAVPLLTFLMLRLSWRWMFVIVGTAGVFLAAIWWAIHRDPAEVRLTGEEVRYLTE
GDENTTTRPPSFAQWRQLFAHRTTWGMIAGFFGTIYTLWMYTGWLPFYLEHERHMSVARVGIVAAIPYFFGCVGAVLGGW
LCDFLTRRGWAPIAGRKLLISCALLGISACTLGTAFAESNAMALTFISISLFLIYIASSAAWATVPIAAPSQYTASLGSI
QNFGGYLGGALAPTVTGLILQRTGSFSQALLLSAGLSALSAVAYLLLVRSPIRTDSAA

Sequences:

>Translated_458_residues
MSPDGTGTNTSIRALIQFSTVSATSVKTSADPDAIRPSARIVSIQRWSIVLLVGGGALNYVDRATLSVANKLIQEDLGIP
VVRMGLLLSAFLWAYAIAQLPVGGLIDRYGPRRLLGLGLFGWSLAQAAGGLVTSFGPFIAARFALGVGEAPLFPGGARVV
RDWFGIRERGFATGLLQSASSLGNFIAVPLLTFLMLRLSWRWMFVIVGTAGVFLAAIWWAIHRDPAEVRLTGEEVRYLTE
GDENTTTRPPSFAQWRQLFAHRTTWGMIAGFFGTIYTLWMYTGWLPFYLEHERHMSVARVGIVAAIPYFFGCVGAVLGGW
LCDFLTRRGWAPIAGRKLLISCALLGISACTLGTAFAESNAMALTFISISLFLIYIASSAAWATVPIAAPSQYTASLGSI
QNFGGYLGGALAPTVTGLILQRTGSFSQALLLSAGLSALSAVAYLLLVRSPIRTDSAA
>Mature_457_residues
SPDGTGTNTSIRALIQFSTVSATSVKTSADPDAIRPSARIVSIQRWSIVLLVGGGALNYVDRATLSVANKLIQEDLGIPV
VRMGLLLSAFLWAYAIAQLPVGGLIDRYGPRRLLGLGLFGWSLAQAAGGLVTSFGPFIAARFALGVGEAPLFPGGARVVR
DWFGIRERGFATGLLQSASSLGNFIAVPLLTFLMLRLSWRWMFVIVGTAGVFLAAIWWAIHRDPAEVRLTGEEVRYLTEG
DENTTTRPPSFAQWRQLFAHRTTWGMIAGFFGTIYTLWMYTGWLPFYLEHERHMSVARVGIVAAIPYFFGCVGAVLGGWL
CDFLTRRGWAPIAGRKLLISCALLGISACTLGTAFAESNAMALTFISISLFLIYIASSAAWATVPIAAPSQYTASLGSIQ
NFGGYLGGALAPTVTGLILQRTGSFSQALLLSAGLSALSAVAYLLLVRSPIRTDSAA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI4885441, Length=377, Percent_Identity=24.6684350132626, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI6912666, Length=386, Percent_Identity=22.5388601036269, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI9945322, Length=371, Percent_Identity=23.4501347708895, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI9966811, Length=384, Percent_Identity=22.3958333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI148743791, Length=347, Percent_Identity=22.7665706051873, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI21322234, Length=374, Percent_Identity=22.9946524064171, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI154350196, Length=403, Percent_Identity=22.5806451612903, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI154800443, Length=384, Percent_Identity=22.9166666666667, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI5031955, Length=249, Percent_Identity=23.6947791164659, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI148728191, Length=298, Percent_Identity=22.1476510067114, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI2367379, Length=436, Percent_Identity=42.2018348623853, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=32.6291079812207, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1789152, Length=450, Percent_Identity=31.5555555555556, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=30.3854875283447, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI2367193, Length=318, Percent_Identity=27.3584905660377, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17554148, Length=348, Percent_Identity=21.8390804597701, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115533554, Length=347, Percent_Identity=24.207492795389, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=347, Percent_Identity=24.207492795389, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554962, Length=348, Percent_Identity=21.8390804597701, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17552542, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17566884, Length=297, Percent_Identity=25.2525252525253, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71997452, Length=411, Percent_Identity=22.6277372262774, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=438, Percent_Identity=22.8310502283105, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=346, Percent_Identity=23.6994219653179, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=364, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=346, Percent_Identity=23.6994219653179, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532009, Length=257, Percent_Identity=25.6809338521401, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86561091, Length=248, Percent_Identity=23.3870967741935, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=275, Percent_Identity=22.5454545454545, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573299, Length=447, Percent_Identity=22.3713646532438, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639764, Length=416, Percent_Identity=23.5576923076923, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24584153, Length=357, Percent_Identity=21.8487394957983, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583789, Length=377, Percent_Identity=22.0159151193634, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648416, Length=423, Percent_Identity=23.1678486997636, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356189, Length=423, Percent_Identity=23.1678486997636, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922400, Length=451, Percent_Identity=22.6164079822616, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641682, Length=403, Percent_Identity=23.0769230769231, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654215, Length=357, Percent_Identity=23.8095238095238, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573708, Length=383, Percent_Identity=20.88772845953, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573707, Length=383, Percent_Identity=20.88772845953, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20130167, Length=351, Percent_Identity=22.7920227920228, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129235, Length=360, Percent_Identity=24.7222222222222, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920686, Length=414, Percent_Identity=21.256038647343, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580790, Length=258, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550460, Length=366, Percent_Identity=23.7704918032787, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24655255, Length=366, Percent_Identity=23.7704918032787, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49073; Mature: 48942

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDGTGTNTSIRALIQFSTVSATSVKTSADPDAIRPSARIVSIQRWSIVLLVGGGALNY
CCCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEEECCCHHHH
VDRATLSVANKLIQEDLGIPVVRMGLLLSAFLWAYAIAQLPVGGLIDRYGPRRLLGLGLF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHH
GWSLAQAAGGLVTSFGPFIAARFALGVGEAPLFPGGARVVRDWFGIRERGFATGLLQSAS
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
SLGNFIAVPLLTFLMLRLSWRWMFVIVGTAGVFLAAIWWAIHRDPAEVRLTGEEVRYLTE
HHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCCCCCCEEECHHHHHEEEC
GDENTTTRPPSFAQWRQLFAHRTTWGMIAGFFGTIYTLWMYTGWLPFYLEHERHMSVARV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHH
GIVAAIPYFFGCVGAVLGGWLCDFLTRRGWAPIAGRKLLISCALLGISACTLGTAFAESN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
AMALTFISISLFLIYIASSAAWATVPIAAPSQYTASLGSIQNFGGYLGGALAPTVTGLIL
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
QRTGSFSQALLLSAGLSALSAVAYLLLVRSPIRTDSAA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SPDGTGTNTSIRALIQFSTVSATSVKTSADPDAIRPSARIVSIQRWSIVLLVGGGALNY
CCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEEECCCHHHH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HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]