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The map label for this gene is ypdA [H]

Identifier: 116623845

GI number: 116623845

Start: 6019000

End: 6019986

Strand: Direct

Name: ypdA [H]

Synonym: Acid_4757

Alternate gene names: 116623845

Gene position: 6019000-6019986 (Clockwise)

Preceding gene: 116623844

Following gene: 116623846

Centisome position: 60.4

GC content: 54.41

Gene sequence:

>987_bases
ATGGCCGAATCATACGACGCACTCGTGGTGGGGGCTGGGCCGACCGGCCTCGCCTGCGGTATCGAGCTGGAACAGCACGG
CGTGAAAACCGTGCTGATCGAGAAAGGCTGCGTGGTGAACTCGATTTATCACTACCCCACCAACATGTCCTTCTTCACTA
CGCCAGAGCTGTTGGAAATCGGTAATATTCCGATGACCAGCCTCAACGAGAAGCCTAACCGTACTGAGGCTCTTAAGTAC
TATCGCAAGGTGGCGGATCACTACCGCCTCGACATCCACCAGTACGAACGCGTGGAAAGCATCGCGGGCGAGGACAACAA
TTTCGAAGTCTTCACCACCAATCGCCTCGGTGAAAACCATGTGTACCGCACGCGCAAGATCGTACTCGCGACCGGCTACT
ACGATGTGGCTAACCAGCTCAACGTACCAGGCGAAGACCTCCATAAAGTACTGCATTACTACAAAGAGCCGCATCCGTAC
TATAACCACGACGTAGCTGTGATCGGCGCTAAGAACTCCGCGGCGATCGCGGCGCTGGAGTTATATTGGACCGGCGCTCG
TGTAACCCTAATACATCGCGGCGCAGCCATCTCCGATTCGGTGAAGTACTGGATTAAGCCGAATATCGAGAACCGGATTA
AGAACGGAGAGATCGCGGCGTACTTTCACTCCAATGTAGTGGAAATCTACAAAGACTCGCTGCGAATTGCGACGCCCAAA
GGCGAAGTCATCATCGCTAACGACTTTGTTTTCGCGCTCGTGGGGTATCGCCCCGACCTGGAATTTCTCGCTGCCACTGG
AATTACGCTGGAACCGGATACTTTGCGCCCGCGCACGAATCCGGAAACTTTGGAGAGTACGCGCGCCGGAATTTTTCTGG
CAGGCGTAATCGTCGCTGGCATGCACACGAACGAAATATTCATTGAGAACGGCCGCTTTCATGGAAGTTTGATCGCACGC
GCGATCGCTTTTCAGGTTTGCGGCTGA

Upstream 100 bases:

>100_bases
CGGTCGTCCCGACATGGCGGAAGCCGGCGGCAAAGATCCGTCCTGCCTGGATGAGGCCTTGACAGCGGTCTACGCCGACG
TGGAAAGCAAGTTGTAACGC

Downstream 100 bases:

>100_bases
GATTCATTTTAATTTTTCGCATTTCGTGTTTGCATTCGTACAGCCGCCCGCCGGAAAGTGCGACTGGAAACTGAAACTTT
GTGACGAAAAGAAGTATCTA

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: thioredoxin disulfide; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAESYDALVVGAGPTGLACGIELEQHGVKTVLIEKGCVVNSIYHYPTNMSFFTTPELLEIGNIPMTSLNEKPNRTEALKY
YRKVADHYRLDIHQYERVESIAGEDNNFEVFTTNRLGENHVYRTRKIVLATGYYDVANQLNVPGEDLHKVLHYYKEPHPY
YNHDVAVIGAKNSAAIAALELYWTGARVTLIHRGAAISDSVKYWIKPNIENRIKNGEIAAYFHSNVVEIYKDSLRIATPK
GEVIIANDFVFALVGYRPDLEFLAATGITLEPDTLRPRTNPETLESTRAGIFLAGVIVAGMHTNEIFIENGRFHGSLIAR
AIAFQVCG

Sequences:

>Translated_328_residues
MAESYDALVVGAGPTGLACGIELEQHGVKTVLIEKGCVVNSIYHYPTNMSFFTTPELLEIGNIPMTSLNEKPNRTEALKY
YRKVADHYRLDIHQYERVESIAGEDNNFEVFTTNRLGENHVYRTRKIVLATGYYDVANQLNVPGEDLHKVLHYYKEPHPY
YNHDVAVIGAKNSAAIAALELYWTGARVTLIHRGAAISDSVKYWIKPNIENRIKNGEIAAYFHSNVVEIYKDSLRIATPK
GEVIIANDFVFALVGYRPDLEFLAATGITLEPDTLRPRTNPETLESTRAGIFLAGVIVAGMHTNEIFIENGRFHGSLIAR
AIAFQVCG
>Mature_327_residues
AESYDALVVGAGPTGLACGIELEQHGVKTVLIEKGCVVNSIYHYPTNMSFFTTPELLEIGNIPMTSLNEKPNRTEALKYY
RKVADHYRLDIHQYERVESIAGEDNNFEVFTTNRLGENHVYRTRKIVLATGYYDVANQLNVPGEDLHKVLHYYKEPHPYY
NHDVAVIGAKNSAAIAALELYWTGARVTLIHRGAAISDSVKYWIKPNIENRIKNGEIAAYFHSNVVEIYKDSLRIATPKG
EVIIANDFVFALVGYRPDLEFLAATGITLEPDTLRPRTNPETLESTRAGIFLAGVIVAGMHTNEIFIENGRFHGSLIARA
IAFQVCG

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: 1.8.1.9

Molecular weight: Translated: 36646; Mature: 36515

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESYDALVVGAGPTGLACGIELEQHGVKTVLIEKGCVVNSIYHYPTNMSFFTTPELLEI
CCCCCCEEEEECCCCCEEEEEEEHHCCCEEEEEECCCEEEEEEECCCCCEEECCCHHHHC
GNIPMTSLNEKPNRTEALKYYRKVADHYRLDIHQYERVESIAGEDNNFEVFTTNRLGENH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHEECHHHHHHHHHHCCCCCCEEEEEECCCCCCC
VYRTRKIVLATGYYDVANQLNVPGEDLHKVLHYYKEPHPYYNHDVAVIGAKNSAAIAALE
EEEEEEEEEEECCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEE
LYWTGARVTLIHRGAAISDSVKYWIKPNIENRIKNGEIAAYFHSNVVEIYKDSLRIATPK
EEECCEEEEEEECCCCCCCCEEEEECCCHHHHCCCCCEEEEEECCHHHHHHCCEEEECCC
GEVIIANDFVFALVGYRPDLEFLAATGITLEPDTLRPRTNPETLESTRAGIFLAGVIVAG
CCEEEECCEEEEEECCCCCHHHHEECCCEECCCCCCCCCCHHHHHHHHCCCEEEEHHHCC
MHTNEIFIENGRFHGSLIARAIAFQVCG
CCCCEEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AESYDALVVGAGPTGLACGIELEQHGVKTVLIEKGCVVNSIYHYPTNMSFFTTPELLEI
CCCCCEEEEECCCCCEEEEEEEHHCCCEEEEEECCCEEEEEEECCCCCEEECCCHHHHC
GNIPMTSLNEKPNRTEALKYYRKVADHYRLDIHQYERVESIAGEDNNFEVFTTNRLGENH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHEECHHHHHHHHHHCCCCCCEEEEEECCCCCCC
VYRTRKIVLATGYYDVANQLNVPGEDLHKVLHYYKEPHPYYNHDVAVIGAKNSAAIAALE
EEEEEEEEEEECCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEE
LYWTGARVTLIHRGAAISDSVKYWIKPNIENRIKNGEIAAYFHSNVVEIYKDSLRIATPK
EEECCEEEEEEECCCCCCCCEEEEECCCHHHHCCCCCEEEEEECCHHHHHHCCEEEECCC
GEVIIANDFVFALVGYRPDLEFLAATGITLEPDTLRPRTNPETLESTRAGIFLAGVIVAG
CCEEEECCEEEEEECCCCCHHHHEECCCEECCCCCCCCCCHHHHHHHHCCCEEEEHHHCC
MHTNEIFIENGRFHGSLIARAIAFQVCG
CCCCEEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: thioredoxin; NADP+

Specific reaction: thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]