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The map label for this gene is grsT [H]

Identifier: 116623802

GI number: 116623802

Start: 5966103

End: 5968088

Strand: Reverse

Name: grsT [H]

Synonym: Acid_4714

Alternate gene names: 116623802

Gene position: 5968088-5966103 (Counterclockwise)

Preceding gene: 116623803

Following gene: 116623801

Centisome position: 59.89

GC content: 65.31

Gene sequence:

>1986_bases
ATGCGCATTTTGCTCGCCCAGAACTCGCTGTACTATCCGGCGCATGGGGGCGGCGATAAATCCAACCGGCTGCTGATCGA
AGCTCTGGCCGCGCTCGGTCACGAGTGCCGCGTGGTCGCCCGCATCAGCGTGTTCGGAGTGCGCGAGCAGGAGCAATACC
TTCAAACTCTTGCCGAACGCGGAGTGATTCCAAACTCCGTCGCGGATGGCGTGGTCACATTCACGCGCGGCGGCGTCACG
ATCCACGTGGTTACCAACGGCAGCCTGCGCGCCACCTTCTCCGCGCAGATCGATGCGTTCGCGCCCGACGTGATACTGGC
CTCCACCGACGACCCCGCGCAACTGCTGCTCGAAGTCGCGCTGCGCAGCCCGGCGCGCGTGGTCTACCTGGCCCGCGCCA
CTCTCGCCGTGCCCTTCGGCCCCGATTGCGCTTTTCCGAGCAAGGCCAAGACCGCGCGCATCCGCGCCTGCGACGCCGTG
GTGGGAGTCAGCCAGTACGTAGCCGATTACATTCGTAAATACGCGGGGCTGGATGCCGTTCACGTTCCGATCTCACTGAT
GGAGCCGGAGGAATGGCCGGACCTCGGCGGCTTCGAGAACGAGTTCGTAACCTTTGTCAATCCTTGCGCGGTGAAGGGCA
TCGCGATCTTTCTCGCGCTCGCCGACGCGTTTCCGCACGTCATTTTCGCCGCCGTACCCACCTGGGGAACCAACCAGCAA
GACCGCGCGTCTCTCGGAGTGCGGCCCAATGTGCGCCTCCTGCAGCCAGTGGACGATATTAATCAACTGCTGGCCCGCAC
CCGTGTCCTGCTGGTGCCTTCATTGTGGGCCGAGGCGCGCTCTCGAATCATTCTGGAAGCGATGCTGCGCGGAGTACCCG
TTATGGCTGCAAATGTCGGCGGAATCCCGGAGGCGATGATGGGTGTTCCCTATTTGCTGCCGGTGCGCGCTATCGAAAGA
TACGAAACCCGGGTCGATGAGCAGATGGTACCTTTGGCCGAAGTGCCGGAACAGGACGCCGCACCGTGGAGGGAAGCGCT
GGCGCGCCTGCTCACGGATCGCGAACACTACACGGAGATCGCTCGCCAATCGCGCGCCGCTGCGCTCGATTATGCGAAGG
AGCTGCACGCCGGCCACCTCGAAAAGATTCTTCTGCAGACGATCGCGAGAGAAAAGCGCTCCATGGCGCAGCCAGTTCGC
CGCGAAGACTCTCTCTCTCCCGAAAAGCGCAAGCTGCTCGCACTCCGTCTACGCAAGCAGGCCGCACCCGCATCGTGGTT
TGCCGGCCTGGACTCCGCGCCCGCGCGCCGGCTCTTCACGTTTCCGCATGCAGGCGGCGGCTCTTCGGCCGGGCCGCTCG
ATTCGCTCGAGGGGTGGAACACCGCGCGAGTTCGTCTTCCCGGCCGCGAATCGCGCCTTGCCGAAGCGCCCTTCGAGCGC
ATGCCCGCGCTGATCACCGCGCTGGCCGACGCCATCGAGCCGCATCTGGATCGCCCCTTCGCCTTCTTCGGCCACTCGAT
GGGCGCCGCGATCGCCTTCGAACTGGCGCGCGAATTGCGCCGCCGCAGCCGGCCACTGCCGGAGACGCTGATCGCCTCCG
GCGCGCGCGCTCCGCAATTCCGCCGCGATCACGTGCCGCCTCCGCCGCCTTCGCGCGAGGCCTTCCTGGAGGAACTCAAG
CGGCTTCAGGGCATCCCCGCGGAGATGCTCGAAGATCCCGCCCTGATGCGCGTCATTCTCCCGGCGCTCGAAGCCGATGC
CGCGCTTTATCGCGCGTATGAATATATGGAAGAGCCGCCGCTCAGCTTTCCGATTCGTGCGTACGGCGGCGAGGCCGACC
CCAACGTGCGCGGTGAGCACCTGGCCGCCTGGGGCGCCCAGACCACGGCTTCTTTTGCCGTCCGCGTTTTTCCCGGCGGA
CATTTTTACTTGAACTCCGCGCGCGAACTGCTGCAGCGCGCGCTTGCCGAGGACCTGCCATCATGA

Upstream 100 bases:

>100_bases
TGCAGCCAGGATTGGCTGCCCCACAAGGCGGCGGGCCGTACGACGGACGCTCCCTTACGGTCGCGGCTCGTTGGGGCGGC
GAGCTGCAAGGTGATCGCTG

Downstream 100 bases:

>100_bases
GTTCCCTCACTCTGAAGCCATTCGAAATCCACGTCTGGCGAATTTGTCTGGATCATGGCGATGTGCCAGCCCCGACGCCC
GGCGAGTCGGCGCGGGCCTT

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRILLAQNSLYYPAHGGGDKSNRLLIEALAALGHECRVVARISVFGVREQEQYLQTLAERGVIPNSVADGVVTFTRGGVT
IHVVTNGSLRATFSAQIDAFAPDVILASTDDPAQLLLEVALRSPARVVYLARATLAVPFGPDCAFPSKAKTARIRACDAV
VGVSQYVADYIRKYAGLDAVHVPISLMEPEEWPDLGGFENEFVTFVNPCAVKGIAIFLALADAFPHVIFAAVPTWGTNQQ
DRASLGVRPNVRLLQPVDDINQLLARTRVLLVPSLWAEARSRIILEAMLRGVPVMAANVGGIPEAMMGVPYLLPVRAIER
YETRVDEQMVPLAEVPEQDAAPWREALARLLTDREHYTEIARQSRAAALDYAKELHAGHLEKILLQTIAREKRSMAQPVR
REDSLSPEKRKLLALRLRKQAAPASWFAGLDSAPARRLFTFPHAGGGSSAGPLDSLEGWNTARVRLPGRESRLAEAPFER
MPALITALADAIEPHLDRPFAFFGHSMGAAIAFELARELRRRSRPLPETLIASGARAPQFRRDHVPPPPPSREAFLEELK
RLQGIPAEMLEDPALMRVILPALEADAALYRAYEYMEEPPLSFPIRAYGGEADPNVRGEHLAAWGAQTTASFAVRVFPGG
HFYLNSARELLQRALAEDLPS

Sequences:

>Translated_661_residues
MRILLAQNSLYYPAHGGGDKSNRLLIEALAALGHECRVVARISVFGVREQEQYLQTLAERGVIPNSVADGVVTFTRGGVT
IHVVTNGSLRATFSAQIDAFAPDVILASTDDPAQLLLEVALRSPARVVYLARATLAVPFGPDCAFPSKAKTARIRACDAV
VGVSQYVADYIRKYAGLDAVHVPISLMEPEEWPDLGGFENEFVTFVNPCAVKGIAIFLALADAFPHVIFAAVPTWGTNQQ
DRASLGVRPNVRLLQPVDDINQLLARTRVLLVPSLWAEARSRIILEAMLRGVPVMAANVGGIPEAMMGVPYLLPVRAIER
YETRVDEQMVPLAEVPEQDAAPWREALARLLTDREHYTEIARQSRAAALDYAKELHAGHLEKILLQTIAREKRSMAQPVR
REDSLSPEKRKLLALRLRKQAAPASWFAGLDSAPARRLFTFPHAGGGSSAGPLDSLEGWNTARVRLPGRESRLAEAPFER
MPALITALADAIEPHLDRPFAFFGHSMGAAIAFELARELRRRSRPLPETLIASGARAPQFRRDHVPPPPPSREAFLEELK
RLQGIPAEMLEDPALMRVILPALEADAALYRAYEYMEEPPLSFPIRAYGGEADPNVRGEHLAAWGAQTTASFAVRVFPGG
HFYLNSARELLQRALAEDLPS
>Mature_661_residues
MRILLAQNSLYYPAHGGGDKSNRLLIEALAALGHECRVVARISVFGVREQEQYLQTLAERGVIPNSVADGVVTFTRGGVT
IHVVTNGSLRATFSAQIDAFAPDVILASTDDPAQLLLEVALRSPARVVYLARATLAVPFGPDCAFPSKAKTARIRACDAV
VGVSQYVADYIRKYAGLDAVHVPISLMEPEEWPDLGGFENEFVTFVNPCAVKGIAIFLALADAFPHVIFAAVPTWGTNQQ
DRASLGVRPNVRLLQPVDDINQLLARTRVLLVPSLWAEARSRIILEAMLRGVPVMAANVGGIPEAMMGVPYLLPVRAIER
YETRVDEQMVPLAEVPEQDAAPWREALARLLTDREHYTEIARQSRAAALDYAKELHAGHLEKILLQTIAREKRSMAQPVR
REDSLSPEKRKLLALRLRKQAAPASWFAGLDSAPARRLFTFPHAGGGSSAGPLDSLEGWNTARVRLPGRESRLAEAPFER
MPALITALADAIEPHLDRPFAFFGHSMGAAIAFELARELRRRSRPLPETLIASGARAPQFRRDHVPPPPPSREAFLEELK
RLQGIPAEMLEDPALMRVILPALEADAALYRAYEYMEEPPLSFPIRAYGGEADPNVRGEHLAAWGAQTTASFAVRVFPGG
HFYLNSARELLQRALAEDLPS

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=216, Percent_Identity=31.0185185185185, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI8922871, Length=186, Percent_Identity=31.7204301075269, Blast_Score=84, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 72566; Mature: 72566

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLAQNSLYYPAHGGGDKSNRLLIEALAALGHECRVVARISVFGVREQEQYLQTLAER
CEEEEECCCEECCCCCCCCCCHHHHHHHHHHCCHHCEEEEEEHHHCCCHHHHHHHHHHHC
GVIPNSVADGVVTFTRGGVTIHVVTNGSLRATFSAQIDAFAPDVILASTDDPAQLLLEVA
CCCCCHHHCCCEEEECCCEEEEEEECCCEEEEEECCHHCCCCCEEEECCCCHHHHHHHHH
LRSPARVVYLARATLAVPFGPDCAFPSKAKTARIRACDAVVGVSQYVADYIRKYAGLDAV
HCCCCEEEEEEEHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
HVPISLMEPEEWPDLGGFENEFVTFVNPCAVKGIAIFLALADAFPHVIFAAVPTWGTNQQ
ECCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DRASLGVRPNVRLLQPVDDINQLLARTRVLLVPSLWAEARSRIILEAMLRGVPVMAANVG
HHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GIPEAMMGVPYLLPVRAIERYETRVDEQMVPLAEVPEQDAAPWREALARLLTDREHYTEI
CCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHCHHHHHHH
ARQSRAAALDYAKELHAGHLEKILLQTIAREKRSMAQPVRREDSLSPEKRKLLALRLRKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAPASWFAGLDSAPARRLFTFPHAGGGSSAGPLDSLEGWNTARVRLPGRESRLAEAPFER
CCCHHHHHCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCHHH
MPALITALADAIEPHLDRPFAFFGHSMGAAIAFELARELRRRSRPLPETLIASGARAPQF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
RRDHVPPPPPSREAFLEELKRLQGIPAEMLEDPALMRVILPALEADAALYRAYEYMEEPP
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSFPIRAYGGEADPNVRGEHLAAWGAQTTASFAVRVFPGGHFYLNSARELLQRALAEDLP
CCCCHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure
MRILLAQNSLYYPAHGGGDKSNRLLIEALAALGHECRVVARISVFGVREQEQYLQTLAER
CEEEEECCCEECCCCCCCCCCHHHHHHHHHHCCHHCEEEEEEHHHCCCHHHHHHHHHHHC
GVIPNSVADGVVTFTRGGVTIHVVTNGSLRATFSAQIDAFAPDVILASTDDPAQLLLEVA
CCCCCHHHCCCEEEECCCEEEEEEECCCEEEEEECCHHCCCCCEEEECCCCHHHHHHHHH
LRSPARVVYLARATLAVPFGPDCAFPSKAKTARIRACDAVVGVSQYVADYIRKYAGLDAV
HCCCCEEEEEEEHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
HVPISLMEPEEWPDLGGFENEFVTFVNPCAVKGIAIFLALADAFPHVIFAAVPTWGTNQQ
ECCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DRASLGVRPNVRLLQPVDDINQLLARTRVLLVPSLWAEARSRIILEAMLRGVPVMAANVG
HHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GIPEAMMGVPYLLPVRAIERYETRVDEQMVPLAEVPEQDAAPWREALARLLTDREHYTEI
CCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHCHHHHHHH
ARQSRAAALDYAKELHAGHLEKILLQTIAREKRSMAQPVRREDSLSPEKRKLLALRLRKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAPASWFAGLDSAPARRLFTFPHAGGGSSAGPLDSLEGWNTARVRLPGRESRLAEAPFER
CCCHHHHHCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCHHH
MPALITALADAIEPHLDRPFAFFGHSMGAAIAFELARELRRRSRPLPETLIASGARAPQF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
RRDHVPPPPPSREAFLEELKRLQGIPAEMLEDPALMRVILPALEADAALYRAYEYMEEPP
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSFPIRAYGGEADPNVRGEHLAAWGAQTTASFAVRVFPGGHFYLNSARELLQRALAEDLP
CCCCHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]