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The map label for this gene is exuT [H]

Identifier: 116623681

GI number: 116623681

Start: 5808410

End: 5809621

Strand: Direct

Name: exuT [H]

Synonym: Acid_4593

Alternate gene names: 116623681

Gene position: 5808410-5809621 (Clockwise)

Preceding gene: 116623678

Following gene: 116623683

Centisome position: 58.28

GC content: 65.43

Gene sequence:

>1212_bases
ATGCTGCTCGCCGCCGTCACCTATCTGGACCGCGTCTGTATTTCCGTTCTCGCCCCCGACATCTCACGCGACCTGGGACT
CGACAAGCTCCAGATGAGCTTCGTCTTCAGCGCCTTCGCCATCGCCTACGCCGGTTTTGAGATCGTCACCGCGTGGTGGG
GCGAACGCGTTGGTGCGCGCCGCATCCTGACGCGAATCGTCGCCTGGTGGTCCTGCTTCACCATCGCCACCGGCCTCTCC
TGGAATTACCCGAGCCTCCTCGCCATCCGCTTCCTGTTTGGCGCGGGCGAAGCCGGTGCGTGGCCCAATGCGGCGCTCGC
CTTCTCCCGCTGGATCCCCACCGGCGAACGCGGCCGCGCCCAGGGATTCTTCTTCGCGGCCGCCCATTTCTCGGGTGGAA
TCACGCCCCTTCTGGTGGCTGCCATGCTGCCGGCCATGTCCTGGCGCGCCATCTTCGCGGCGTGCGGGACCGTGGGTTTC
GTGTGGGCCGCCGGCTGGTACCGCTGGTTTCGCGACGAACCTCGCGAGCACAAGGCCGTCAATGCAGCCGAAGCCGAGCT
GATCGAAACCGGCCGCCGCATCGCTGTCCACATGCATTCCGGCGGGGCCGTCTGGCGCGCACTGGCCGCCTCTCCCAACG
TCTGGTTCCTCTGCCTGGCCTATTTCAGCAACAGCTACGGATCCTATTTCGTGATGACCTGGCTGCCCACCTACCTCTCC
GAGCAGCGCCATTTCCAGAAAGAATCGCTGAGCTTATTCTCCGGTCTTCCCCTTCTCCTCAGCGTCTTCGGCGACCTGAG
CGGCGGCGCTCTCACGGATTGGATGACGCGCCGCTTCGGCCTCCGCGTGGGCCGCTCCGCGGTTTGCGTCGCGGGCTATT
CCGTGGCTGCGGCCGCGATGTTCGCATCGGTATACTCGGCAACTCCGGTGCTTGCGGCCTGCCTGATCGCGGTCGCGGTC
GCCGCCTCTATGGTCACCCTGAGCGCGACTTGGGCTGCCTGCATGGATATCGGCGGCGAACACACCGCGGTGCTCAGCGC
CGCCATGAATACCACCGGACAACTGGGCTCGATCATCAGCCCGGTTGCCACCGGATGGGTCGTGAGCCGCTTTTCCAACT
GGCAGGCGCCGCTCGTGATCATGGGCGTACTTTACCTGATCTCCGCCGTACTCTGGACGATGGTGGACGCGCGCAAGCGC
CTTCAGGTCTGA

Upstream 100 bases:

>100_bases
ACGGTAGCAAAGCGGCCACTTGTGCCGCGAGGTCAAAAACAGAGATGCTGTTGGGGCGATGCTTCCCACGCGAACCCGAT
ACCGCGCAGCCGGACTGTTG

Downstream 100 bases:

>100_bases
TCCAAACCGGCCCGGGCCCGCAGTCCTAACTTCTTGAGCAGCCCGATGGCCTGCTCCCGCTCGGCAAGCGTCAGTCCGGC
CGCCGCCCGCTCCATCGCGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLLAAVTYLDRVCISVLAPDISRDLGLDKLQMSFVFSAFAIAYAGFEIVTAWWGERVGARRILTRIVAWWSCFTIATGLS
WNYPSLLAIRFLFGAGEAGAWPNAALAFSRWIPTGERGRAQGFFFAAAHFSGGITPLLVAAMLPAMSWRAIFAACGTVGF
VWAAGWYRWFRDEPREHKAVNAAEAELIETGRRIAVHMHSGGAVWRALAASPNVWFLCLAYFSNSYGSYFVMTWLPTYLS
EQRHFQKESLSLFSGLPLLLSVFGDLSGGALTDWMTRRFGLRVGRSAVCVAGYSVAAAAMFASVYSATPVLAACLIAVAV
AASMVTLSATWAACMDIGGEHTAVLSAAMNTTGQLGSIISPVATGWVVSRFSNWQAPLVIMGVLYLISAVLWTMVDARKR
LQV

Sequences:

>Translated_403_residues
MLLAAVTYLDRVCISVLAPDISRDLGLDKLQMSFVFSAFAIAYAGFEIVTAWWGERVGARRILTRIVAWWSCFTIATGLS
WNYPSLLAIRFLFGAGEAGAWPNAALAFSRWIPTGERGRAQGFFFAAAHFSGGITPLLVAAMLPAMSWRAIFAACGTVGF
VWAAGWYRWFRDEPREHKAVNAAEAELIETGRRIAVHMHSGGAVWRALAASPNVWFLCLAYFSNSYGSYFVMTWLPTYLS
EQRHFQKESLSLFSGLPLLLSVFGDLSGGALTDWMTRRFGLRVGRSAVCVAGYSVAAAAMFASVYSATPVLAACLIAVAV
AASMVTLSATWAACMDIGGEHTAVLSAAMNTTGQLGSIISPVATGWVVSRFSNWQAPLVIMGVLYLISAVLWTMVDARKR
LQV
>Mature_403_residues
MLLAAVTYLDRVCISVLAPDISRDLGLDKLQMSFVFSAFAIAYAGFEIVTAWWGERVGARRILTRIVAWWSCFTIATGLS
WNYPSLLAIRFLFGAGEAGAWPNAALAFSRWIPTGERGRAQGFFFAAAHFSGGITPLLVAAMLPAMSWRAIFAACGTVGF
VWAAGWYRWFRDEPREHKAVNAAEAELIETGRRIAVHMHSGGAVWRALAASPNVWFLCLAYFSNSYGSYFVMTWLPTYLS
EQRHFQKESLSLFSGLPLLLSVFGDLSGGALTDWMTRRFGLRVGRSAVCVAGYSVAAAAMFASVYSATPVLAACLIAVAV
AASMVTLSATWAACMDIGGEHTAVLSAAMNTTGQLGSIISPVATGWVVSRFSNWQAPLVIMGVLYLISAVLWTMVDARKR
LQV

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=388, Percent_Identity=22.4226804123711, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI148743791, Length=339, Percent_Identity=22.1238938053097, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI9966811, Length=377, Percent_Identity=20.9549071618037, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI9945322, Length=320, Percent_Identity=21.875, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI148728191, Length=266, Percent_Identity=22.9323308270677, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI21322234, Length=319, Percent_Identity=21.6300940438871, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5031955, Length=228, Percent_Identity=24.5614035087719, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI154350196, Length=384, Percent_Identity=20.0520833333333, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI154800443, Length=298, Percent_Identity=20.1342281879195, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4885441, Length=274, Percent_Identity=21.8978102189781, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI2367379, Length=381, Percent_Identity=27.5590551181102, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789515, Length=425, Percent_Identity=26.8235294117647, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789152, Length=423, Percent_Identity=25.7683215130024, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082320, Length=412, Percent_Identity=26.6990291262136, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI2367193, Length=413, Percent_Identity=23.2445520581114, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87081723, Length=223, Percent_Identity=27.3542600896861, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533554, Length=320, Percent_Identity=23.75, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115533556, Length=320, Percent_Identity=23.75, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25141341, Length=300, Percent_Identity=22.6666666666667, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=300, Percent_Identity=22.6666666666667, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=300, Percent_Identity=22.6666666666667, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17552542, Length=385, Percent_Identity=22.5974025974026, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17554148, Length=353, Percent_Identity=20.6798866855524, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17557432, Length=250, Percent_Identity=25.2, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534564, Length=250, Percent_Identity=25.2, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=297, Percent_Identity=23.9057239057239, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=274, Percent_Identity=22.992700729927, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=290, Percent_Identity=21.7241379310345, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=196, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536337, Length=258, Percent_Identity=25.968992248062, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535049, Length=420, Percent_Identity=19.7619047619048, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534558, Length=196, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32567120, Length=222, Percent_Identity=23.4234234234234, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17561502, Length=222, Percent_Identity=23.4234234234234, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24654215, Length=407, Percent_Identity=22.8501228501229, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI19922400, Length=407, Percent_Identity=22.8501228501229, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24648416, Length=380, Percent_Identity=22.8947368421053, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356189, Length=380, Percent_Identity=22.8947368421053, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583789, Length=345, Percent_Identity=23.4782608695652, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24653727, Length=360, Percent_Identity=24.4444444444444, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641682, Length=278, Percent_Identity=24.8201438848921, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20130167, Length=354, Percent_Identity=21.7514124293785, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20129235, Length=386, Percent_Identity=22.5388601036269, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573708, Length=389, Percent_Identity=21.5938303341902, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573707, Length=389, Percent_Identity=21.5938303341902, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24658658, Length=389, Percent_Identity=23.1362467866324, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24658696, Length=359, Percent_Identity=23.6768802228412, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584153, Length=352, Percent_Identity=21.0227272727273, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550460, Length=431, Percent_Identity=22.5058004640371, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24655255, Length=407, Percent_Identity=22.1130221130221, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573299, Length=423, Percent_Identity=22.4586288416076, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580790, Length=321, Percent_Identity=20.8722741433022, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658666, Length=375, Percent_Identity=21.0666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639764, Length=396, Percent_Identity=21.7171717171717, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550495, Length=339, Percent_Identity=19.4690265486726, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI62484226, Length=284, Percent_Identity=24.6478873239437, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43754; Mature: 43754

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAAVTYLDRVCISVLAPDISRDLGLDKLQMSFVFSAFAIAYAGFEIVTAWWGERVGAR
CHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILTRIVAWWSCFTIATGLSWNYPSLLAIRFLFGAGEAGAWPNAALAFSRWIPTGERGRA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCC
QGFFFAAAHFSGGITPLLVAAMLPAMSWRAIFAACGTVGFVWAAGWYRWFRDEPREHKAV
CEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
NAAEAELIETGRRIAVHMHSGGAVWRALAASPNVWFLCLAYFSNSYGSYFVMTWLPTYLS
CHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHH
EQRHFQKESLSLFSGLPLLLSVFGDLSGGALTDWMTRRFGLRVGRSAVCVAGYSVAAAAM
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FASVYSATPVLAACLIAVAVAASMVTLSATWAACMDIGGEHTAVLSAAMNTTGQLGSIIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
PVATGWVVSRFSNWQAPLVIMGVLYLISAVLWTMVDARKRLQV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLAAVTYLDRVCISVLAPDISRDLGLDKLQMSFVFSAFAIAYAGFEIVTAWWGERVGAR
CHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILTRIVAWWSCFTIATGLSWNYPSLLAIRFLFGAGEAGAWPNAALAFSRWIPTGERGRA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCC
QGFFFAAAHFSGGITPLLVAAMLPAMSWRAIFAACGTVGFVWAAGWYRWFRDEPREHKAV
CEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
NAAEAELIETGRRIAVHMHSGGAVWRALAASPNVWFLCLAYFSNSYGSYFVMTWLPTYLS
CHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHH
EQRHFQKESLSLFSGLPLLLSVFGDLSGGALTDWMTRRFGLRVGRSAVCVAGYSVAAAAM
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FASVYSATPVLAACLIAVAVAASMVTLSATWAACMDIGGEHTAVLSAAMNTTGQLGSIIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
PVATGWVVSRFSNWQAPLVIMGVLYLISAVLWTMVDARKRLQV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]