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The map label for this gene is 116623645

Identifier: 116623645

GI number: 116623645

Start: 5758884

End: 5759870

Strand: Reverse

Name: 116623645

Synonym: Acid_4557

Alternate gene names: NA

Gene position: 5759870-5758884 (Counterclockwise)

Preceding gene: 116623646

Following gene: 116623644

Centisome position: 57.8

GC content: 63.93

Gene sequence:

>987_bases
TTGCATTACAATGCGAAGCAGTCCATGGCCGGCACGGAGAGCGGAAGCGGTCCGCAATTTCCCAGGCACTTCGACGGAAA
GCGCTTCTACAATCCGAATGCGCGTCAGGCGCCCGGGCTGCTTGACGTCCTGCGCTGGAAGCTGACCAGCCGCCGGAAGC
GGTCGCCGAGGTTCATCGCGGACGTCACGCCATCCGTTCCGCCGCGCCGCGTGGAAGGCGACGGCCTGCGCGTCACGCTG
GTCAATCACTCGACCTTACTGCTGCAGCATCGCGGTATGAACATTCTGACCGATCCGATCTGGTCCGGGCGCGCGAGCCC
CTTCTCGTGGATCGGCCCGCGGCGGCGGAGAGCGCCGGGAGTCCGTTGGGAAGACCTGCCGCCGATCGACGCGGTGCTGA
TCAGCCACAATCATTACGATCACCTCGATCTGCCTACGCTGCGGCGGCTGTCGGAGCGCGGCGATTCCGTATTCGTGGTT
CCTGCCGGCGTGGCGCGGCCGCTTCTCTCGGAGGGCGTCGCGCCGGTTCACGAACTGGATTGGGGCGAATCCTTATCTCT
GCCCGGCCTGGCGATTCACGCTGTTCCGGCCTTGCATTTTTCGGGAAGGGGTGTGTTCGACCGCAACCGTTCCTTGTGGT
GCGGGTACCTGCTCGAATCCGCGGGCCGGCTGCTCTATTTCGCGGGAGACACCGCGTTCGGTGATCATTTCGCCGCGATT
CGGGAGTGGTTCGGACCGCCGGACCTGGCTCTGTTGCCGGTCGGCGCGTACCTGCCGCGGTGGTTCATGTCGCCGGTCCA
TATGGCGCCGGACGATGCGGTGAGGGCACATGAGATCCTGGCGGCCCAGACCAGCATCGCGATTCACCACGGAACTTTCC
AACTCGCTGACGACGGTATCGATTCGGCGAAGCAGGAACTTGCCGGGATCGAAAAGCACGAGCCGTTCCTGGTGATCCAC
AATGGTGAATTCGCGGAGTTTCCATGA

Upstream 100 bases:

>100_bases
AAGGGCGCCGACGCGATCGTACCGGCGCCGATTCACCGCGTCCACTTCGTGGGACGGTAGCTGTGTGACGGTAGCTGTGT
GATTTGCCGTCTTCCGCTGC

Downstream 100 bases:

>100_bases
CGGTGGACAAACATACGCTCGCAATCCTCAGCATTGTGGGCTGTTCTCTGGATGTGCTCGGTACCCTGTATCTCGCATAC
GATCTTCTTGGCGGCGAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MHYNAKQSMAGTESGSGPQFPRHFDGKRFYNPNARQAPGLLDVLRWKLTSRRKRSPRFIADVTPSVPPRRVEGDGLRVTL
VNHSTLLLQHRGMNILTDPIWSGRASPFSWIGPRRRRAPGVRWEDLPPIDAVLISHNHYDHLDLPTLRRLSERGDSVFVV
PAGVARPLLSEGVAPVHELDWGESLSLPGLAIHAVPALHFSGRGVFDRNRSLWCGYLLESAGRLLYFAGDTAFGDHFAAI
REWFGPPDLALLPVGAYLPRWFMSPVHMAPDDAVRAHEILAAQTSIAIHHGTFQLADDGIDSAKQELAGIEKHEPFLVIH
NGEFAEFP

Sequences:

>Translated_328_residues
MHYNAKQSMAGTESGSGPQFPRHFDGKRFYNPNARQAPGLLDVLRWKLTSRRKRSPRFIADVTPSVPPRRVEGDGLRVTL
VNHSTLLLQHRGMNILTDPIWSGRASPFSWIGPRRRRAPGVRWEDLPPIDAVLISHNHYDHLDLPTLRRLSERGDSVFVV
PAGVARPLLSEGVAPVHELDWGESLSLPGLAIHAVPALHFSGRGVFDRNRSLWCGYLLESAGRLLYFAGDTAFGDHFAAI
REWFGPPDLALLPVGAYLPRWFMSPVHMAPDDAVRAHEILAAQTSIAIHHGTFQLADDGIDSAKQELAGIEKHEPFLVIH
NGEFAEFP
>Mature_328_residues
MHYNAKQSMAGTESGSGPQFPRHFDGKRFYNPNARQAPGLLDVLRWKLTSRRKRSPRFIADVTPSVPPRRVEGDGLRVTL
VNHSTLLLQHRGMNILTDPIWSGRASPFSWIGPRRRRAPGVRWEDLPPIDAVLISHNHYDHLDLPTLRRLSERGDSVFVV
PAGVARPLLSEGVAPVHELDWGESLSLPGLAIHAVPALHFSGRGVFDRNRSLWCGYLLESAGRLLYFAGDTAFGDHFAAI
REWFGPPDLALLPVGAYLPRWFMSPVHMAPDDAVRAHEILAAQTSIAIHHGTFQLADDGIDSAKQELAGIEKHEPFLVIH
NGEFAEFP

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=319, Percent_Identity=37.3040752351097, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI170932481, Length=319, Percent_Identity=37.3040752351097, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17543100, Length=297, Percent_Identity=35.3535353535354, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI25148824, Length=297, Percent_Identity=35.3535353535354, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17543102, Length=334, Percent_Identity=33.8323353293413, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17543104, Length=333, Percent_Identity=35.1351351351351, Blast_Score=185, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6325154, Length=253, Percent_Identity=35.1778656126482, Blast_Score=149, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36514; Mature: 36514

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYNAKQSMAGTESGSGPQFPRHFDGKRFYNPNARQAPGLLDVLRWKLTSRRKRSPRFIA
CCCCCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
DVTPSVPPRRVEGDGLRVTLVNHSTLLLQHRGMNILTDPIWSGRASPFSWIGPRRRRAPG
ECCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEECCCCCCCCCCCHHCCCHHHCCCC
VRWEDLPPIDAVLISHNHYDHLDLPTLRRLSERGDSVFVVPAGVARPLLSEGVAPVHELD
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHCC
WGESLSLPGLAIHAVPALHFSGRGVFDRNRSLWCGYLLESAGRLLYFAGDTAFGDHFAAI
CCCCCCCCCEEEEEEEEEEECCCCEECCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHH
REWFGPPDLALLPVGAYLPRWFMSPVHMAPDDAVRAHEILAAQTSIAIHHGTFQLADDGI
HHHCCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCEEEECCCCH
DSAKQELAGIEKHEPFLVIHNGEFAEFP
HHHHHHHHCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MHYNAKQSMAGTESGSGPQFPRHFDGKRFYNPNARQAPGLLDVLRWKLTSRRKRSPRFIA
CCCCCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
DVTPSVPPRRVEGDGLRVTLVNHSTLLLQHRGMNILTDPIWSGRASPFSWIGPRRRRAPG
ECCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEECCCCCCCCCCCHHCCCHHHCCCC
VRWEDLPPIDAVLISHNHYDHLDLPTLRRLSERGDSVFVVPAGVARPLLSEGVAPVHELD
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHCC
WGESLSLPGLAIHAVPALHFSGRGVFDRNRSLWCGYLLESAGRLLYFAGDTAFGDHFAAI
CCCCCCCCCEEEEEEEEEEECCCCEECCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHH
REWFGPPDLALLPVGAYLPRWFMSPVHMAPDDAVRAHEILAAQTSIAIHHGTFQLADDGI
HHHCCCCCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEECCEEEECCCCH
DSAKQELAGIEKHEPFLVIHNGEFAEFP
HHHHHHHHCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]