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The map label for this gene is qor [H]

Identifier: 116623611

GI number: 116623611

Start: 5720293

End: 5721294

Strand: Direct

Name: qor [H]

Synonym: Acid_4521

Alternate gene names: 116623611

Gene position: 5720293-5721294 (Clockwise)

Preceding gene: 116623610

Following gene: 116623615

Centisome position: 57.4

GC content: 65.27

Gene sequence:

>1002_bases
ATGGTTGCGGCTGGCGAGGCGATAAGACTTCATACTAGGGTCATGAAGTTCATTTCGTTAGAGGCGCCGGGCGGGCCCGA
GGTCCTTCATCTTGCCGAGGGTGCCGAGCCGACTCCTGGGCCGACGGAAGTAGTGATTCGAGTGGAGGCGGCGGGTGTCA
ACCGGCCGGACCTTCAGCAGCGGGCGGGAAAGTATCCGCCGCCGCCGGACGCATCGCCGGTCCTCGGACTGGAGGTCGCG
GGAATCGTGGCCGCGGCGGGCGCGGAGTCAGGATTGCGCGAAGGCGAGTCGGTATGCGCGCTGACTCCCGGCGGCGGGTA
TGCCGAGTACTGCCTGGTCGCGGGTGTGCAGTGTTTGCCGGTACCGCGCGGGCTGTCCATGGAGGAGGCCGCCGGAATTC
CAGAGACGTTTTTCACCGTCTGGGCCAACGTCTTCCAGATCGGAAGATTGGTGGCCGGAGAAAAGTTCCTGGTGCATGGC
GGATCGAGCGGCATCGGCACGACCGCGATTCAGCTGGCGCACGCGTTCGGGGCGACGGTGTTCACCACGGCGGGCAGCGA
AGCGAAGTGCCGCGCCAGCGAGGCGCTCGGGGCGGCGCGCGCGATCAACTACAAGGAGCGCGATTTCGTGGCGGAATTCG
CGGGAGTCGATTTGATCCTGGATATCGTGGGCGCGGCGTATACACCGCGCAATATCGAATGCCTGGCGCCGCGGGGACGG
CTGGTGCAGATCGCGGTGCAAAAGGGCGCCGAGGCGACGGTCAATCTGGCGAAGGTGATGCAGAAGCGGCTGACGATTAC
GGGTTCCACGATGCGGCCGCGATCGGTCGCGGAGAAGGGGGCGATCGCCCGCGAACTTTACGAGAAGGTCTGGCCGCTGC
TGGAATCGGGACGGGTGAAGGTGCTGGTGGATCGCGTTTTCCCGCTGGCCGAGGCGGCGGAGGCGCACCGATATTTAGAG
GCCGGCGAGCATATCGGTAAAGTCATTCTGAAGGTGGCGTAG

Upstream 100 bases:

>100_bases
CGAGCAGACCAATGCACAGTAGTACGGTGCTGCGAGCCGCAAATTGAGATCGTGGTTTGCGCGTGCAACGGACGCGCCCT
CACGGTCGCGGCTCGGATGG

Downstream 100 bases:

>100_bases
TGGCCCACATCAGATTGGCGATCGAGCTTTCCCGACTGTAAATCCACCCGTCATCGCTCCCAAATCCGAGCCGGTCGGTA
ATTGACAGATCTCCACAGAT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MVAAGEAIRLHTRVMKFISLEAPGGPEVLHLAEGAEPTPGPTEVVIRVEAAGVNRPDLQQRAGKYPPPPDASPVLGLEVA
GIVAAAGAESGLREGESVCALTPGGGYAEYCLVAGVQCLPVPRGLSMEEAAGIPETFFTVWANVFQIGRLVAGEKFLVHG
GSSGIGTTAIQLAHAFGATVFTTAGSEAKCRASEALGAARAINYKERDFVAEFAGVDLILDIVGAAYTPRNIECLAPRGR
LVQIAVQKGAEATVNLAKVMQKRLTITGSTMRPRSVAEKGAIARELYEKVWPLLESGRVKVLVDRVFPLAEAAEAHRYLE
AGEHIGKVILKVA

Sequences:

>Translated_333_residues
MVAAGEAIRLHTRVMKFISLEAPGGPEVLHLAEGAEPTPGPTEVVIRVEAAGVNRPDLQQRAGKYPPPPDASPVLGLEVA
GIVAAAGAESGLREGESVCALTPGGGYAEYCLVAGVQCLPVPRGLSMEEAAGIPETFFTVWANVFQIGRLVAGEKFLVHG
GSSGIGTTAIQLAHAFGATVFTTAGSEAKCRASEALGAARAINYKERDFVAEFAGVDLILDIVGAAYTPRNIECLAPRGR
LVQIAVQKGAEATVNLAKVMQKRLTITGSTMRPRSVAEKGAIARELYEKVWPLLESGRVKVLVDRVFPLAEAAEAHRYLE
AGEHIGKVILKVA
>Mature_333_residues
MVAAGEAIRLHTRVMKFISLEAPGGPEVLHLAEGAEPTPGPTEVVIRVEAAGVNRPDLQQRAGKYPPPPDASPVLGLEVA
GIVAAAGAESGLREGESVCALTPGGGYAEYCLVAGVQCLPVPRGLSMEEAAGIPETFFTVWANVFQIGRLVAGEKFLVHG
GSSGIGTTAIQLAHAFGATVFTTAGSEAKCRASEALGAARAINYKERDFVAEFAGVDLILDIVGAAYTPRNIECLAPRGR
LVQIAVQKGAEATVNLAKVMQKRLTITGSTMRPRSVAEKGAIARELYEKVWPLLESGRVKVLVDRVFPLAEAAEAHRYLE
AGEHIGKVILKVA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=39.3939393939394, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=39.3939393939394, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI194239674, Length=339, Percent_Identity=30.3834808259587, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI13236495, Length=339, Percent_Identity=30.3834808259587, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=27.9742765273312, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI194239676, Length=333, Percent_Identity=29.7297297297297, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI24308257, Length=348, Percent_Identity=28.1609195402299, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI41872631, Length=316, Percent_Identity=29.746835443038, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI28557745, Length=320, Percent_Identity=26.875, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI47519420, Length=339, Percent_Identity=26.2536873156342, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI197927207, Length=186, Percent_Identity=28.494623655914, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=329, Percent_Identity=32.2188449848024, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507255, Length=301, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=316, Percent_Identity=29.1139240506329, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=23.6526946107784, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=333, Percent_Identity=25.5255255255255, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=333, Percent_Identity=24.3243243243243, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=333, Percent_Identity=23.7237237237237, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920632, Length=309, Percent_Identity=29.4498381877023, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221330659, Length=302, Percent_Identity=28.476821192053, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=30.9963099630996, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34965; Mature: 34965

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAAGEAIRLHTRVMKFISLEAPGGPEVLHLAEGAEPTPGPTEVVIRVEAAGVNRPDLQQ
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCHHH
RAGKYPPPPDASPVLGLEVAGIVAAAGAESGLREGESVCALTPGGGYAEYCLVAGVQCLP
HCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHHHHCCCEEEC
VPRGLSMEEAAGIPETFFTVWANVFQIGRLVAGEKFLVHGGSSGIGTTAIQLAHAFGATV
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCEE
FTTAGSEAKCRASEALGAARAINYKERDFVAEFAGVDLILDIVGAAYTPRNIECLAPRGR
EEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
LVQIAVQKGAEATVNLAKVMQKRLTITGSTMRPRSVAEKGAIARELYEKVWPLLESGRVK
EEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
VLVDRVFPLAEAAEAHRYLEAGEHIGKVILKVA
EEEEHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAAGEAIRLHTRVMKFISLEAPGGPEVLHLAEGAEPTPGPTEVVIRVEAAGVNRPDLQQ
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCHHH
RAGKYPPPPDASPVLGLEVAGIVAAAGAESGLREGESVCALTPGGGYAEYCLVAGVQCLP
HCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHHHHCCCEEEC
VPRGLSMEEAAGIPETFFTVWANVFQIGRLVAGEKFLVHGGSSGIGTTAIQLAHAFGATV
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCEE
FTTAGSEAKCRASEALGAARAINYKERDFVAEFAGVDLILDIVGAAYTPRNIECLAPRGR
EEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCC
LVQIAVQKGAEATVNLAKVMQKRLTITGSTMRPRSVAEKGAIARELYEKVWPLLESGRVK
EEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
VLVDRVFPLAEAAEAHRYLEAGEHIGKVILKVA
EEEEHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]