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The map label for this gene is pgk

Identifier: 116623511

GI number: 116623511

Start: 5593005

End: 5594180

Strand: Reverse

Name: pgk

Synonym: Acid_4421

Alternate gene names: 116623511

Gene position: 5594180-5593005 (Counterclockwise)

Preceding gene: 116623512

Following gene: 116623508

Centisome position: 56.13

GC content: 63.44

Gene sequence:

>1176_bases
ATGTCCTATTTATCGATTCGTGATCTCGACTTGAAGGGCAAGCGTGTCTTCATCCGCGTGGATTTCAATGTGCCGCTGCA
AAAGAACGATCAGGGCGCAATGGAAATCACCAGCGACAAGCGCATCAAAGCGTCGCTGCCCACGATTCAATACGCGCTGG
AGCATGGCGCGGCGGTGATTCTGGCGTCGCACCTGGGGCGTCCCAAGGGGAAGCCGAATACGGAGATGAGCCTGAAGCCC
GTGGCGGCGAGGCTGGAGCAGGTGCTGAAAGTCCCGGTGAAGATGGCTCCCGATTGCGTGGGTCCCGAAGTGCAGGCGAT
GCTGCCGGCGCCGGGCGAGGTGCTGCTGCTGGAAAATTTGCGCTTCCACGCCGAGGAAGAGAAGAACGACCCCGCATTTG
CCGCCCAGTTGGCGGCTCTGTGCGAGATTTATGTCAACGACGCATTCGGGTCGGCGCACCGCGCGCACGCATCCACCGAA
GGCATGGTCAAGTTAGTGAAGCAGGCGGCGGCCGGCCTGTTGATGGAAAAGGAACTGAAGTATCTGGGGATGGCGACCAC
GAATCCGCCGCGGCCGTGCGTGGCGATTCTGGGCGGCGCGAAGGTCTCCGACAAGATCGAGGTCATCCAGAATTTGGGCA
AGGTGGTGGACCGCCTGTTGATCGGCGGCGCGATGGCGTACACGTTCCTCAAGGCGCAGGGGCTGCCGACCGGAAAGTCG
CTGGTGGAGGACGACAAGGTCGAACTGGCGAAGAGTCTGCTGGCGGAATTGGGAGAGCGCCTGATGCTGCCGGTGGACCA
CGTGGTGGTCTCGGAGATCGCGGCGGGCGCGCCCTTCGAGGTGGTGGATACCATTCCCGAGGGCAAGATCGCGGTGGATA
TCGGCCCCAAGACGGTGGAGGCATTCTCCAAAGTGGTGGCCGGCGCGAAGACGGTGATCTGGAATGGTCCGATGGGGATC
TTCGAGAAGCCGCCCTTCGATCAGGGCACGGTGGCGGTGGCGAAAGCGGTCGCCGGATCGGGCGCGACCAGCATAGTGGG
CGGCGGCGATTCGGAGAAGGCGATCAAGGCGGCCGGCGTCAGCGACAAAATCTCGCACGTGTCGACGGGCGGCGGAGCAT
CGCTGGAGTTCCTGGCAGGCGACACGCTGCCGGGCGTCGCGGCGCTGGACCGGTAG

Upstream 100 bases:

>100_bases
GGCCGGCTTTACTTTGGCAGTATCGACACGGCTGCCATCGGCTGGGCCCCGGCGCCGCGGAATTAGCAATCAGGCGCCAC
ATGTTAATCTCAAGCCTGAT

Downstream 100 bases:

>100_bases
CGATATCGGGGGGGGTGGCAGGCGGCAGCGCCAGTCCCCCGATTATTTCGCAGTTCGAGTGGCTGTGCCGGTGCCTTTGG
CGGGCGTGCCTTGAACGTCG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSYLSIRDLDLKGKRVFIRVDFNVPLQKNDQGAMEITSDKRIKASLPTIQYALEHGAAVILASHLGRPKGKPNTEMSLKP
VAARLEQVLKVPVKMAPDCVGPEVQAMLPAPGEVLLLENLRFHAEEEKNDPAFAAQLAALCEIYVNDAFGSAHRAHASTE
GMVKLVKQAAAGLLMEKELKYLGMATTNPPRPCVAILGGAKVSDKIEVIQNLGKVVDRLLIGGAMAYTFLKAQGLPTGKS
LVEDDKVELAKSLLAELGERLMLPVDHVVVSEIAAGAPFEVVDTIPEGKIAVDIGPKTVEAFSKVVAGAKTVIWNGPMGI
FEKPPFDQGTVAVAKAVAGSGATSIVGGGDSEKAIKAAGVSDKISHVSTGGGASLEFLAGDTLPGVAALDR

Sequences:

>Translated_391_residues
MSYLSIRDLDLKGKRVFIRVDFNVPLQKNDQGAMEITSDKRIKASLPTIQYALEHGAAVILASHLGRPKGKPNTEMSLKP
VAARLEQVLKVPVKMAPDCVGPEVQAMLPAPGEVLLLENLRFHAEEEKNDPAFAAQLAALCEIYVNDAFGSAHRAHASTE
GMVKLVKQAAAGLLMEKELKYLGMATTNPPRPCVAILGGAKVSDKIEVIQNLGKVVDRLLIGGAMAYTFLKAQGLPTGKS
LVEDDKVELAKSLLAELGERLMLPVDHVVVSEIAAGAPFEVVDTIPEGKIAVDIGPKTVEAFSKVVAGAKTVIWNGPMGI
FEKPPFDQGTVAVAKAVAGSGATSIVGGGDSEKAIKAAGVSDKISHVSTGGGASLEFLAGDTLPGVAALDR
>Mature_390_residues
SYLSIRDLDLKGKRVFIRVDFNVPLQKNDQGAMEITSDKRIKASLPTIQYALEHGAAVILASHLGRPKGKPNTEMSLKPV
AARLEQVLKVPVKMAPDCVGPEVQAMLPAPGEVLLLENLRFHAEEEKNDPAFAAQLAALCEIYVNDAFGSAHRAHASTEG
MVKLVKQAAAGLLMEKELKYLGMATTNPPRPCVAILGGAKVSDKIEVIQNLGKVVDRLLIGGAMAYTFLKAQGLPTGKSL
VEDDKVELAKSLLAELGERLMLPVDHVVVSEIAAGAPFEVVDTIPEGKIAVDIGPKTVEAFSKVVAGAKTVIWNGPMGIF
EKPPFDQGTVAVAKAVAGSGATSIVGGGDSEKAIKAAGVSDKISHVSTGGGASLEFLAGDTLPGVAALDR

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI31543397, Length=415, Percent_Identity=45.5421686746988, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI4505763, Length=415, Percent_Identity=45.0602409638554, Blast_Score=327, Evalue=2e-89,
Organism=Escherichia coli, GI1789294, Length=394, Percent_Identity=46.9543147208122, Blast_Score=332, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17508823, Length=418, Percent_Identity=47.6076555023923, Blast_Score=345, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6319857, Length=415, Percent_Identity=49.1566265060241, Blast_Score=347, Evalue=2e-96,
Organism=Drosophila melanogaster, GI17136394, Length=417, Percent_Identity=47.242206235012, Blast_Score=332, Evalue=3e-91,
Organism=Drosophila melanogaster, GI24581203, Length=415, Percent_Identity=46.2650602409639, Blast_Score=328, Evalue=3e-90,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_SOLUE (Q01Y83)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_825667.1
- ProteinModelPortal:   Q01Y83
- SMR:   Q01Y83
- STRING:   Q01Y83
- GeneID:   4427310
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_4421
- NMPDR:   fig|234267.9.peg.4207
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   DCIGDEV
- PhylomeDB:   Q01Y83
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 41050; Mature: 40919

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 41-41 BINDING 121-121 BINDING 154-154 BINDING 205-205 BINDING 322-322

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLSIRDLDLKGKRVFIRVDFNVPLQKNDQGAMEITSDKRIKASLPTIQYALEHGAAVI
CCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCEEEECCCHHHHHHHCCCCEE
LASHLGRPKGKPNTEMSLKPVAARLEQVLKVPVKMAPDCVGPEVQAMLPAPGEVLLLENL
EEHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCEEECCCCCCEEEEECC
RFHAEEEKNDPAFAAQLAALCEIYVNDAFGSAHRAHASTEGMVKLVKQAAAGLLMEKELK
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YLGMATTNPPRPCVAILGGAKVSDKIEVIQNLGKVVDRLLIGGAMAYTFLKAQGLPTGKS
HHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LVEDDKVELAKSLLAELGERLMLPVDHVVVSEIAAGAPFEVVDTIPEGKIAVDIGPKTVE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECHHHHH
AFSKVVAGAKTVIWNGPMGIFEKPPFDQGTVAVAKAVAGSGATSIVGGGDSEKAIKAAGV
HHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHCCC
SDKISHVSTGGGASLEFLAGDTLPGVAALDR
CHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SYLSIRDLDLKGKRVFIRVDFNVPLQKNDQGAMEITSDKRIKASLPTIQYALEHGAAVI
CCCEEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCEEEECCCHHHHHHHCCCCEE
LASHLGRPKGKPNTEMSLKPVAARLEQVLKVPVKMAPDCVGPEVQAMLPAPGEVLLLENL
EEHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCEEECCCCCCEEEEECC
RFHAEEEKNDPAFAAQLAALCEIYVNDAFGSAHRAHASTEGMVKLVKQAAAGLLMEKELK
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YLGMATTNPPRPCVAILGGAKVSDKIEVIQNLGKVVDRLLIGGAMAYTFLKAQGLPTGKS
HHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LVEDDKVELAKSLLAELGERLMLPVDHVVVSEIAAGAPFEVVDTIPEGKIAVDIGPKTVE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECHHHHH
AFSKVVAGAKTVIWNGPMGIFEKPPFDQGTVAVAKAVAGSGATSIVGGGDSEKAIKAAGV
HHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHCCC
SDKISHVSTGGGASLEFLAGDTLPGVAALDR
CHHHHHCCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA