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The map label for this gene is abcA [H]

Identifier: 116623503

GI number: 116623503

Start: 5581997

End: 5583238

Strand: Direct

Name: abcA [H]

Synonym: Acid_4413

Alternate gene names: 116623503

Gene position: 5581997-5583238 (Clockwise)

Preceding gene: 116623497

Following gene: 116623504

Centisome position: 56.01

GC content: 62.88

Gene sequence:

>1242_bases
TTGGGTCAAGGTGAAATTGTAGCAACGCAGCCACTACAATTAAGGTTGGTCCTCGTACAAAACGTTTCCAAGCTCTACCG
TCTTTATCGCCGCCCCAGTGAGCGTCTGCGCGAAATGCTCCCTGGCAGCAAGCCGCGGCACACCGATTTCTGGGCTCTTA
AGGACATCGGCTTCGAAGTCGAGAAAGGCGAGTGCCTCGGCCTGGTCGGCCCCAACGGCTGCGGCAAGAGCACCCTGCTG
CAAATCGTCAGCGGTATTCTGCAGCCCACCACGGGACGCGTGGTCACGCGTGGTCGTATCGCCGCCCTGCTCGAACTCGG
CGCCGGTTTCAATCCCGAGTTTTCGGGGCGCGAGAACGTCTATCTCAACGGCGAGATCATGGGGCTCAGCCGCGGCGAAA
TCGATCGCGCCATGCCTTCCATCGAAGCCTTCGCCGAAATCGGCGAGTTCATCGGGCGGCCCGTCAAGGAATACTCCAGC
GGCATGTACGTGCGGCTCGCCTTTTCCACCGCCATCCACGTGGATCCGGAAATCCTGATCGTCGATGAGGCCCTCGCGGT
CGGCGACGCCGTCTTCGCCAATCGCTGCGTGCGCAAGTTCGAGGAGCTGCGCGAGCGCAAGATCACCGTGCTGTTCGTCT
CCCACGATCTCGGCCTGGTCAAAGCGCTCAGCGACCGAGCCATCCTGCTGCTCAACGGCCGCATCGAGGCGCAGGGCACG
CCCAACGACGTGATCAACCGCTATATCGGCCTGGTCCTGGCGCGCCAGCAGGCTACCAACAAGAAAGAAGACCGCGTGCG
CGGCAGTTTCCGCCACGGCGATGGCACCAGCGAGATCCTCAGCGTCGAAATCCTGAATGGCGCGGGTGAACCCGCCGCCT
CCGTAGCCAGCGGCGAGGACGTAACAGTTCGTGTACGCCTGCGCTTTCACGCCGCCGCCAGCGACCCCATGGTCGGCATC
CTGGTGCGTACCCGCATCGGCATCGACGTCTACGGCACCAACACCCGCATCGAACAAAAGGCGCTCGGCAATTTCCAGCC
GGGCGATGAACTGGAGATCGACTTTCAATTCGCCTGCTGGCTGACACCGCAGCAGTACACGCTGACGGTGGCGAGCCAGG
CCGCCGATGGCTCCAGCCACGACTGGCTCGACGACGCCATCGCGTTTGACGTGGTCGATACGCGCATCGCTGCCGGCGTC
GCCAACCTGAGGGCGGGCATTCAATGGCGCGTCTCACGGTAA

Upstream 100 bases:

>100_bases
TCCACCGGGGTCCTGCGGTGGTCCGTTCCGCCGCGCGGCGTGACCGCGCGGCCAGCTTTCTCAGGGCCCCGCACAATACA
CCCTCATACATCCAGGATGA

Downstream 100 bases:

>100_bases
GGGTCCATCCCCGCGCCCGCCGCTCCGAAATCACCGGGCGCCTCGGCGACGCGTGGAAGCTCGCGCTGGCCGCTCCGCCG
GTCGATGGCAAGGCCAACGA

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MGQGEIVATQPLQLRLVLVQNVSKLYRLYRRPSERLREMLPGSKPRHTDFWALKDIGFEVEKGECLGLVGPNGCGKSTLL
QIVSGILQPTTGRVVTRGRIAALLELGAGFNPEFSGRENVYLNGEIMGLSRGEIDRAMPSIEAFAEIGEFIGRPVKEYSS
GMYVRLAFSTAIHVDPEILIVDEALAVGDAVFANRCVRKFEELRERKITVLFVSHDLGLVKALSDRAILLLNGRIEAQGT
PNDVINRYIGLVLARQQATNKKEDRVRGSFRHGDGTSEILSVEILNGAGEPAASVASGEDVTVRVRLRFHAAASDPMVGI
LVRTRIGIDVYGTNTRIEQKALGNFQPGDELEIDFQFACWLTPQQYTLTVASQAADGSSHDWLDDAIAFDVVDTRIAAGV
ANLRAGIQWRVSR

Sequences:

>Translated_413_residues
MGQGEIVATQPLQLRLVLVQNVSKLYRLYRRPSERLREMLPGSKPRHTDFWALKDIGFEVEKGECLGLVGPNGCGKSTLL
QIVSGILQPTTGRVVTRGRIAALLELGAGFNPEFSGRENVYLNGEIMGLSRGEIDRAMPSIEAFAEIGEFIGRPVKEYSS
GMYVRLAFSTAIHVDPEILIVDEALAVGDAVFANRCVRKFEELRERKITVLFVSHDLGLVKALSDRAILLLNGRIEAQGT
PNDVINRYIGLVLARQQATNKKEDRVRGSFRHGDGTSEILSVEILNGAGEPAASVASGEDVTVRVRLRFHAAASDPMVGI
LVRTRIGIDVYGTNTRIEQKALGNFQPGDELEIDFQFACWLTPQQYTLTVASQAADGSSHDWLDDAIAFDVVDTRIAAGV
ANLRAGIQWRVSR
>Mature_412_residues
GQGEIVATQPLQLRLVLVQNVSKLYRLYRRPSERLREMLPGSKPRHTDFWALKDIGFEVEKGECLGLVGPNGCGKSTLLQ
IVSGILQPTTGRVVTRGRIAALLELGAGFNPEFSGRENVYLNGEIMGLSRGEIDRAMPSIEAFAEIGEFIGRPVKEYSSG
MYVRLAFSTAIHVDPEILIVDEALAVGDAVFANRCVRKFEELRERKITVLFVSHDLGLVKALSDRAILLLNGRIEAQGTP
NDVINRYIGLVLARQQATNKKEDRVRGSFRHGDGTSEILSVEILNGAGEPAASVASGEDVTVRVRLRFHAAASDPMVGIL
VRTRIGIDVYGTNTRIEQKALGNFQPGDELEIDFQFACWLTPQQYTLTVASQAADGSSHDWLDDAIAFDVVDTRIAAGVA
NLRAGIQWRVSR

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=202, Percent_Identity=27.2277227722772, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI31657092, Length=225, Percent_Identity=28, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI27262624, Length=210, Percent_Identity=25.2380952380952, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI27262626, Length=210, Percent_Identity=25.2380952380952, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI30795238, Length=214, Percent_Identity=22.8971962616822, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI27881501, Length=214, Percent_Identity=22.8971962616822, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI153792144, Length=211, Percent_Identity=24.6445497630332, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI6005701, Length=205, Percent_Identity=25.8536585365854, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI27477115, Length=202, Percent_Identity=27.7227722772277, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI150417984, Length=244, Percent_Identity=23.7704918032787, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI42741659, Length=238, Percent_Identity=27.7310924369748, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI148612844, Length=237, Percent_Identity=28.6919831223629, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI47078218, Length=265, Percent_Identity=23.0188679245283, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI255708477, Length=235, Percent_Identity=28.936170212766, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI45446740, Length=265, Percent_Identity=23.0188679245283, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI157502203, Length=242, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI157502201, Length=242, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9961252, Length=219, Percent_Identity=27.8538812785388, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4505771, Length=219, Percent_Identity=27.8538812785388, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081709, Length=204, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082267, Length=213, Percent_Identity=30.0469483568075, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789032, Length=253, Percent_Identity=25.6916996047431, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787370, Length=211, Percent_Identity=27.0142180094787, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787758, Length=222, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788210, Length=201, Percent_Identity=31.3432835820896, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788761, Length=207, Percent_Identity=26.5700483091787, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790467, Length=199, Percent_Identity=27.1356783919598, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=24.0196078431373, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788165, Length=205, Percent_Identity=30.7317073170732, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994943, Length=215, Percent_Identity=24.6511627906977, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787500, Length=225, Percent_Identity=25.7777777777778, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789891, Length=214, Percent_Identity=26.6355140186916, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787712, Length=213, Percent_Identity=27.2300469483568, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI48995001, Length=217, Percent_Identity=27.6497695852535, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=25.3588516746411, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081782, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789593, Length=209, Percent_Identity=27.7511961722488, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790739, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081834, Length=204, Percent_Identity=31.3725490196078, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786253, Length=201, Percent_Identity=25.8706467661692, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788225, Length=211, Percent_Identity=26.0663507109005, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788506, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786698, Length=183, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788450, Length=223, Percent_Identity=24.2152466367713, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789873, Length=202, Percent_Identity=26.2376237623762, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787112, Length=212, Percent_Identity=28.7735849056604, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786319, Length=198, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790525, Length=232, Percent_Identity=23.7068965517241, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=242, Percent_Identity=25.2066115702479, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115533608, Length=251, Percent_Identity=24.3027888446215, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=219, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=219, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=219, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=219, Percent_Identity=27.3972602739726, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=192, Percent_Identity=25, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221500365, Length=192, Percent_Identity=25, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24582014, Length=217, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582012, Length=217, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221512771, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648314, Length=228, Percent_Identity=25.4385964912281, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 45313; Mature: 45182

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00436 PEROXIDASE_2 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQGEIVATQPLQLRLVLVQNVSKLYRLYRRPSERLREMLPGSKPRHTDFWALKDIGFEV
CCCCCEEEECCCEEEEHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEHHCCEEE
EKGECLGLVGPNGCGKSTLLQIVSGILQPTTGRVVTRGRIAALLELGAGFNPEFSGRENV
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCCCCEE
YLNGEIMGLSRGEIDRAMPSIEAFAEIGEFIGRPVKEYSSGMYVRLAFSTAIHVDPEILI
EECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEEEECCCCEEE
VDEALAVGDAVFANRCVRKFEELRERKITVLFVSHDLGLVKALSDRAILLLNGRIEAQGT
EECHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCHHHHHHCCCEEEEEECEEECCCC
PNDVINRYIGLVLARQQATNKKEDRVRGSFRHGDGTSEILSVEILNGAGEPAASVASGED
CHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHCCCCCC
VTVRVRLRFHAAASDPMVGILVRTRIGIDVYGTNTRIEQKALGNFQPGDELEIDFQFACW
EEEEEEEEEEECCCCCEEEEEEEEEECEEEECCCCEEHHHHCCCCCCCCCEEEEEEEEEE
LTPQQYTLTVASQAADGSSHDWLDDAIAFDVVDTRIAAGVANLRAGIQWRVSR
ECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
GQGEIVATQPLQLRLVLVQNVSKLYRLYRRPSERLREMLPGSKPRHTDFWALKDIGFEV
CCCCEEEECCCEEEEHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEHHCCEEE
EKGECLGLVGPNGCGKSTLLQIVSGILQPTTGRVVTRGRIAALLELGAGFNPEFSGRENV
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCCCCEE
YLNGEIMGLSRGEIDRAMPSIEAFAEIGEFIGRPVKEYSSGMYVRLAFSTAIHVDPEILI
EECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEEEECCCCEEE
VDEALAVGDAVFANRCVRKFEELRERKITVLFVSHDLGLVKALSDRAILLLNGRIEAQGT
EECHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCHHHHHHCCCEEEEEECEEECCCC
PNDVINRYIGLVLARQQATNKKEDRVRGSFRHGDGTSEILSVEILNGAGEPAASVASGED
CHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHCCCCCC
VTVRVRLRFHAAASDPMVGILVRTRIGIDVYGTNTRIEQKALGNFQPGDELEIDFQFACW
EEEEEEEEEEECCCCCEEEEEEEEEECEEEECCCCEEHHHHCCCCCCCCCEEEEEEEEEE
LTPQQYTLTVASQAADGSSHDWLDDAIAFDVVDTRIAAGVANLRAGIQWRVSR
ECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]