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The map label for this gene is arnC [H]

Identifier: 116623443

GI number: 116623443

Start: 5514604

End: 5516007

Strand: Direct

Name: arnC [H]

Synonym: Acid_4352

Alternate gene names: 116623443

Gene position: 5514604-5516007 (Clockwise)

Preceding gene: 116623442

Following gene: 116623448

Centisome position: 55.34

GC content: 62.75

Gene sequence:

>1404_bases
ATGAAACTATCCATTCTGGTGCCTCTCTACAACGAGGAAGAGGCTGTCGCCACGCTGCTCGAACGTGTGATCGCAGCACC
CTTGCCGGCGGGCATGGAGCGCGAGATTATCGTCGCGGACGATGGGTCCACGGACGCTTCGGTGGAAGAGGTGGAGCGGG
TGGCGGCGGCGCATCCCGGCATCATCCGGCTGCTGCGCGCCGATCGCAATCGCGGAAAGGGCGACGCGCTGCGCCGGACA
ATCGCGGAGGCCTGCGGCGAATTTGCCATCGTGCAGGACGCCGACCTGGAGTACGACCCGCGCGAGTATGAGCGCATTCT
GGCGCCCCTGCTGGACGGCCGCGCCGACGCAGTCTTCGGATCCCGCTTTATGGTTTCCGGCGAGCGCCGCGTCCTCTATT
TCTGGCATTCGCTGGCCAACCACCTGCTCACCGGGATGTGCAACATCTTCGCCGATCTCAACCTGACCGACATGGAGACC
TGCTACAAGGCTTTCCGCACACCGCTGCTCAAAAGCATTCCGATCCGCAGCGAGCGATTCGGCTTTGAACCGGAGATCAC
CATCAAGCTGGCGAAGCGGCAGGCGCGCATTTATGAGACGCCGATCAGTTACAACGGCCGCACTTACGACGAGGGAAAGA
AGATCGGGCTTAAGGACGCCTTCGAAGCATTCTGGGTAATCCTATCGTCGTCTGTGTCCGGCGACATTTACGTGGATAAG
GACAAGGGCATTCTCGACGCCTTTTCGAGCGCACCGAATTTCAACCGCTGGATGGCCGATACCATCCGGCCTTACATCGG
CAAGTACGTGCTCGAGATCGGCGCGGGGATCGGCAACTTAAGCCGCATCCTGATGGGTGGACGCAAGCGCTACGTCGCGA
CCGACCTGGATGCCGAGCACCTGGAGCGCCTGCGCGCCCGACTTTCCACGCGTCCGCACCTGGAGACCGCGATCCTGGAC
GCGGCGCGCGCCGAGGATGGCCTGCCCTTCCGCGGACAGATGGATACCGTGGTCTGCCTCAACGTGGTGGAGCACATCGA
GGACGATCTCAGCGCCCTACGCAATATTCACGCGGCGCTGGTAGAAGGCGGCCGCGCGATCATTCTGGTGCCCGAAGGGC
AAAGCATCTTCTGCTCCCTGGATGAGGAGTTGGGCCACTTCCGCCGCTACTCGGAGAGCCAGCTTCGCGGCCGCATGCGG
GAGGCCGGCTTCCAGGTGGAAGCCCTGCTGCGCTTCAACCGGATTTCGCGGCCGGGATGGTGGCTGAATGGAAAGATCCT
GAAACGCCGGAGCATCAGCCGCAGTCAACTGAAGAACTTCGACCGGCTGGTCTGGCTCTTCCGCCGCATCGACCCGCACC
TTCCCTGGTCGCCGACTTCGATCATCGCCGTGGGCCGCAAGTAG

Upstream 100 bases:

>100_bases
GACGGTCGCGGCTCTGAAGAGTATTCGGGGCGGGGAGCTGTCGGACTGGTATACTCGCTTTTTTGGGTGCCGCTCCGCTG
TTGGCCCTCGCCTATCGCTG

Downstream 100 bases:

>100_bases
CGGTGGCTAGCGCGTCTTCCATGCGTTCCTCCAAAGGGCGCGTTTGTCCACGATGAGCCTCGAACCGAGCATTTTGGTGG
AGCAGCCGCCGTCGCGGCGG

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKLSILVPLYNEEEAVATLLERVIAAPLPAGMEREIIVADDGSTDASVEEVERVAAAHPGIIRLLRADRNRGKGDALRRT
IAEACGEFAIVQDADLEYDPREYERILAPLLDGRADAVFGSRFMVSGERRVLYFWHSLANHLLTGMCNIFADLNLTDMET
CYKAFRTPLLKSIPIRSERFGFEPEITIKLAKRQARIYETPISYNGRTYDEGKKIGLKDAFEAFWVILSSSVSGDIYVDK
DKGILDAFSSAPNFNRWMADTIRPYIGKYVLEIGAGIGNLSRILMGGRKRYVATDLDAEHLERLRARLSTRPHLETAILD
AARAEDGLPFRGQMDTVVCLNVVEHIEDDLSALRNIHAALVEGGRAIILVPEGQSIFCSLDEELGHFRRYSESQLRGRMR
EAGFQVEALLRFNRISRPGWWLNGKILKRRSISRSQLKNFDRLVWLFRRIDPHLPWSPTSIIAVGRK

Sequences:

>Translated_467_residues
MKLSILVPLYNEEEAVATLLERVIAAPLPAGMEREIIVADDGSTDASVEEVERVAAAHPGIIRLLRADRNRGKGDALRRT
IAEACGEFAIVQDADLEYDPREYERILAPLLDGRADAVFGSRFMVSGERRVLYFWHSLANHLLTGMCNIFADLNLTDMET
CYKAFRTPLLKSIPIRSERFGFEPEITIKLAKRQARIYETPISYNGRTYDEGKKIGLKDAFEAFWVILSSSVSGDIYVDK
DKGILDAFSSAPNFNRWMADTIRPYIGKYVLEIGAGIGNLSRILMGGRKRYVATDLDAEHLERLRARLSTRPHLETAILD
AARAEDGLPFRGQMDTVVCLNVVEHIEDDLSALRNIHAALVEGGRAIILVPEGQSIFCSLDEELGHFRRYSESQLRGRMR
EAGFQVEALLRFNRISRPGWWLNGKILKRRSISRSQLKNFDRLVWLFRRIDPHLPWSPTSIIAVGRK
>Mature_467_residues
MKLSILVPLYNEEEAVATLLERVIAAPLPAGMEREIIVADDGSTDASVEEVERVAAAHPGIIRLLRADRNRGKGDALRRT
IAEACGEFAIVQDADLEYDPREYERILAPLLDGRADAVFGSRFMVSGERRVLYFWHSLANHLLTGMCNIFADLNLTDMET
CYKAFRTPLLKSIPIRSERFGFEPEITIKLAKRQARIYETPISYNGRTYDEGKKIGLKDAFEAFWVILSSSVSGDIYVDK
DKGILDAFSSAPNFNRWMADTIRPYIGKYVLEIGAGIGNLSRILMGGRKRYVATDLDAEHLERLRARLSTRPHLETAILD
AARAEDGLPFRGQMDTVVCLNVVEHIEDDLSALRNIHAALVEGGRAIILVPEGQSIFCSLDEELGHFRRYSESQLRGRMR
EAGFQVEALLRFNRISRPGWWLNGKILKRRSISRSQLKNFDRLVWLFRRIDPHLPWSPTSIIAVGRK

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=219, Percent_Identity=26.4840182648402, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788588, Length=212, Percent_Identity=26.4150943396226, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325029, Length=230, Percent_Identity=25.6521739130435, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585265, Length=215, Percent_Identity=24.6511627906977, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 52830; Mature: 52830

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSILVPLYNEEEAVATLLERVIAAPLPAGMEREIIVADDGSTDASVEEVERVAAAHPG
CEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHH
IIRLLRADRNRGKGDALRRTIAEACGEFAIVQDADLEYDPREYERILAPLLDGRADAVFG
HHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEC
SRFMVSGERRVLYFWHSLANHLLTGMCNIFADLNLTDMETCYKAFRTPLLKSIPIRSERF
CEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHC
GFEPEITIKLAKRQARIYETPISYNGRTYDEGKKIGLKDAFEAFWVILSSSVSGDIYVDK
CCCCCEEEEEEHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEC
DKGILDAFSSAPNFNRWMADTIRPYIGKYVLEIGAGIGNLSRILMGGRKRYVATDLDAEH
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCHHH
LERLRARLSTRPHLETAILDAARAEDGLPFRGQMDTVVCLNVVEHIEDDLSALRNIHAAL
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VEGGRAIILVPEGQSIFCSLDEELGHFRRYSESQLRGRMREAGFQVEALLRFNRISRPGW
HCCCCEEEEEECCCEEEEECHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
WLNGKILKRRSISRSQLKNFDRLVWLFRRIDPHLPWSPTSIIAVGRK
EECCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MKLSILVPLYNEEEAVATLLERVIAAPLPAGMEREIIVADDGSTDASVEEVERVAAAHPG
CEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHH
IIRLLRADRNRGKGDALRRTIAEACGEFAIVQDADLEYDPREYERILAPLLDGRADAVFG
HHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEC
SRFMVSGERRVLYFWHSLANHLLTGMCNIFADLNLTDMETCYKAFRTPLLKSIPIRSERF
CEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHC
GFEPEITIKLAKRQARIYETPISYNGRTYDEGKKIGLKDAFEAFWVILSSSVSGDIYVDK
CCCCCEEEEEEHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEC
DKGILDAFSSAPNFNRWMADTIRPYIGKYVLEIGAGIGNLSRILMGGRKRYVATDLDAEH
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCHHH
LERLRARLSTRPHLETAILDAARAEDGLPFRGQMDTVVCLNVVEHIEDDLSALRNIHAAL
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VEGGRAIILVPEGQSIFCSLDEELGHFRRYSESQLRGRMREAGFQVEALLRFNRISRPGW
HCCCCEEEEEECCCEEEEECHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
WLNGKILKRRSISRSQLKNFDRLVWLFRRIDPHLPWSPTSIIAVGRK
EECCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA