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The map label for this gene is araR [H]

Identifier: 116623440

GI number: 116623440

Start: 5511122

End: 5512264

Strand: Reverse

Name: araR [H]

Synonym: Acid_4349

Alternate gene names: 116623440

Gene position: 5512264-5511122 (Counterclockwise)

Preceding gene: 116623444

Following gene: 116623439

Centisome position: 55.31

GC content: 64.92

Gene sequence:

>1143_bases
GTGACGGTCGTATTAAAACCAATTTATCAGCAGATTACAGAGCGGCTGGAGCGCGATATCCGTGGCGGAAAGTACGCCGC
GGGGCAGAAGTTCCCCAGCGAAGCGGCTCTCATCCAGCGCTTCGGCGTATCCCGTATTACGGTGGGCCGCGCGGTCCGCG
AGTTGCAGCAGCGAGGTCTGCTGGATAGGGTGGCCGGCTCCGGCACCTACGTGCGCGGCGCCGAACAGCAGCGCCGCGGC
GGACTTCTCTTCGGCCTGGTCATCCCCAATCTCGGCGAGACCGAGATCTTCGAACCCATCTGTCAGGGTATCGCCGCCTC
ACACGACGCCGTGGGCCATGCGCTCCTCTGGGCGCACGCCGACCAGGGTCGTTTATCGGAACCGCGACCGTCAGGGAGCG
ATCCCAAAGAAGAGCAGGCCATCGAGCTCGCGCGTCAATCCATCGCCCGCCGGGTCGCAGGAATTTTCTTCGCTCCGCTG
GAATTCAGCGCCTCTAGCGCCCGCGTGAACTTGCGGGTCATGAAGCTGATCGAAGCCGCGCGCATCCCCGTAGTGCTGCT
CGACCGCCGCCCCGAAGAATCCACCGGTCGCCGCGCGTGCGACCTGGTCGGCATCGATAATCACCGCGCCGGCTACATCG
CAACCGAACACCTGCTTCGTCAGGGCGTGCGCCGCGTCGGCTTTGTGCGTGTCGAAGGCCAGGCCACGACCATCAAGGCG
CGCGTCCGCGGCTTCCACGACGCACTGCGCGAATTTGACGCCGCCGGCCACGTCCTCACCATGCCTGCCGCGGAGCGCTT
CCCGCTCACCACCGCCATCCGCGAATGCGAGGCCTTCGTGTGCGCTAACGATCGTGTGGCGGCGCGCATCATGCAGACGC
TGCTCGCAGCCGGGTTGCGCATCCCGCGCGACGTCCGCATTGTCGGCATCGACGACGTGAATTACGCCGCCCTCCTGCCG
GTGCCCTTAACCACCGTTCACCAGCCCTGCCGCGATATCGGTGAGACTGCGCTGCGAGTCATGCTGGAACGTCTGGATCG
ACCCAAAATGCCGGCGCGCGATGTCCTGTTGGAATGCAGCCTTGTGGTTCGCGAATCCTGCGGCGCCGCTTCGATGGATC
TTTTTCCGGCGGAAAGCGTATGA

Upstream 100 bases:

>100_bases
GGGTCACCTACGTGGACGATCGCATCCCATATCTGATGGGATGAGTTTTTATTATGGCAGGTTGCTTTTCTGCGCATAAA
GCTGATATAACAGCTTCACG

Downstream 100 bases:

>100_bases
CCTGCCATGAACGTGATGCACTCGGTAATCGCTGCCGTTCTTCTCTCTGCAGTGGCCTTTGGGCAGACCGCCCCGGCTCG
CCTCGAATTCGAGGTGGCTT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTVVLKPIYQQITERLERDIRGGKYAAGQKFPSEAALIQRFGVSRITVGRAVRELQQRGLLDRVAGSGTYVRGAEQQRRG
GLLFGLVIPNLGETEIFEPICQGIAASHDAVGHALLWAHADQGRLSEPRPSGSDPKEEQAIELARQSIARRVAGIFFAPL
EFSASSARVNLRVMKLIEAARIPVVLLDRRPEESTGRRACDLVGIDNHRAGYIATEHLLRQGVRRVGFVRVEGQATTIKA
RVRGFHDALREFDAAGHVLTMPAAERFPLTTAIRECEAFVCANDRVAARIMQTLLAAGLRIPRDVRIVGIDDVNYAALLP
VPLTTVHQPCRDIGETALRVMLERLDRPKMPARDVLLECSLVVRESCGAASMDLFPAESV

Sequences:

>Translated_380_residues
MTVVLKPIYQQITERLERDIRGGKYAAGQKFPSEAALIQRFGVSRITVGRAVRELQQRGLLDRVAGSGTYVRGAEQQRRG
GLLFGLVIPNLGETEIFEPICQGIAASHDAVGHALLWAHADQGRLSEPRPSGSDPKEEQAIELARQSIARRVAGIFFAPL
EFSASSARVNLRVMKLIEAARIPVVLLDRRPEESTGRRACDLVGIDNHRAGYIATEHLLRQGVRRVGFVRVEGQATTIKA
RVRGFHDALREFDAAGHVLTMPAAERFPLTTAIRECEAFVCANDRVAARIMQTLLAAGLRIPRDVRIVGIDDVNYAALLP
VPLTTVHQPCRDIGETALRVMLERLDRPKMPARDVLLECSLVVRESCGAASMDLFPAESV
>Mature_379_residues
TVVLKPIYQQITERLERDIRGGKYAAGQKFPSEAALIQRFGVSRITVGRAVRELQQRGLLDRVAGSGTYVRGAEQQRRGG
LLFGLVIPNLGETEIFEPICQGIAASHDAVGHALLWAHADQGRLSEPRPSGSDPKEEQAIELARQSIARRVAGIFFAPLE
FSASSARVNLRVMKLIEAARIPVVLLDRRPEESTGRRACDLVGIDNHRAGYIATEHLLRQGVRRVGFVRVEGQATTIKAR
VRGFHDALREFDAAGHVLTMPAAERFPLTTAIRECEAFVCANDRVAARIMQTLLAAGLRIPRDVRIVGIDDVNYAALLPV
PLTTVHQPCRDIGETALRVMLERLDRPKMPARDVLLECSLVVRESCGAASMDLFPAESV

Specific function: Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=233, Percent_Identity=24.8927038626609, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790369, Length=174, Percent_Identity=27.0114942528736, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786950, Length=67, Percent_Identity=44.7761194029851, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789202, Length=180, Percent_Identity=26.1111111111111, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR001761
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 41787; Mature: 41656

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVLKPIYQQITERLERDIRGGKYAAGQKFPSEAALIQRFGVSRITVGRAVRELQQRGL
CEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCC
LDRVAGSGTYVRGAEQQRRGGLLFGLVIPNLGETEIFEPICQGIAASHDAVGHALLWAHA
HHHHCCCCCEEECCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEC
DQGRLSEPRPSGSDPKEEQAIELARQSIARRVAGIFFAPLEFSASSARVNLRVMKLIEAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHH
RIPVVLLDRRPEESTGRRACDLVGIDNHRAGYIATEHLLRQGVRRVGFVRVEGQATTIKA
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCEEEECCCCHHHHH
RVRGFHDALREFDAAGHVLTMPAAERFPLTTAIRECEAFVCANDRVAARIMQTLLAAGLR
HHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
IPRDVRIVGIDDVNYAALLPVPLTTVHQPCRDIGETALRVMLERLDRPKMPARDVLLECS
CCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LVVRESCGAASMDLFPAESV
HHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVVLKPIYQQITERLERDIRGGKYAAGQKFPSEAALIQRFGVSRITVGRAVRELQQRGL
EEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCC
LDRVAGSGTYVRGAEQQRRGGLLFGLVIPNLGETEIFEPICQGIAASHDAVGHALLWAHA
HHHHCCCCCEEECCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEC
DQGRLSEPRPSGSDPKEEQAIELARQSIARRVAGIFFAPLEFSASSARVNLRVMKLIEAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHH
RIPVVLLDRRPEESTGRRACDLVGIDNHRAGYIATEHLLRQGVRRVGFVRVEGQATTIKA
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCEEEECCCCHHHHH
RVRGFHDALREFDAAGHVLTMPAAERFPLTTAIRECEAFVCANDRVAARIMQTLLAAGLR
HHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
IPRDVRIVGIDDVNYAALLPVPLTTVHQPCRDIGETALRVMLERLDRPKMPARDVLLECS
CCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LVVRESCGAASMDLFPAESV
HHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9045819; 9384377; 10417639; 11418559 [H]