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The map label for this gene is atoS [H]

Identifier: 116623388

GI number: 116623388

Start: 5442816

End: 5444516

Strand: Direct

Name: atoS [H]

Synonym: Acid_4297

Alternate gene names: 116623388

Gene position: 5442816-5444516 (Clockwise)

Preceding gene: 116623387

Following gene: 116623389

Centisome position: 54.62

GC content: 63.37

Gene sequence:

>1701_bases
ATGAGCGGCGAACTCACAGGCGAGGCGCTGCAGAAGCTGCGCCACGACCTGCGTACGCCGATCAACCACATTCTGGGCTA
CACCGACATGCTGGTGGAGGATGCCGCCGAGATCGGCATTTCCGCGTTCGTGGAGCCGCTCCGCAAGATCCGCGCCGGGG
GGCGGACGCTGCTGGAGTTGATTCAATCGTCGTTAGGCGAAGGCATGCTGGCGGTGAACGCGGAGGCGATGGCGGCTTTC
GAATCGCGCTTCCGCTCGCGGGCGCAGACGCTGTTGATTTCGGCGCGAGAGCTGGAAGAGGAGTTTCAGCGCGCGGCCAG
CGAAGATGCGCGCACCGACATCCAGCGCGTAGTGGCGGCGCTGGAGCGGCTGATTGCGATGTCCAGCGGCACCGGGGAGA
GCGAGGATGCAGCGCCGCCGGAGACGGAGCGGGTAGCGCTCCCTGACGGTCGCGGCTCGTTGGGGCTGGAGAGCGGTGGG
CGGATATTGATCGCCGAGGACAACCCGGCGAATCGCGACATCCTGCGGCGGCGCCTGGAAAAAGACGGGCATGTGGTTAC
CGAGACGCAGGACGGCAGGGAGGCGCTGGAGCAACTGGAGCGGGGCGATTTCGACCTGCTGCTGCTGGATATCCTGATGC
CGCGGCTGGACGGCTTCGAGACCCTGGCTTACATCCGGCGCAACGAGCGGTTCCACGATCTTCCGGTGATCATGATTTCG
GCGCTCGACGAAATCCAGAGCGTGGTGCGCTGCATAGAGATGGGCGCGGAGGATTACCTGCCGAAGCCGATCGACCCAGT
GCTGCTGCGCGCGCGGATCGGCGCGAGCCTGGAAAAGAAGCGCCTGCGCGACCGCGAGCGGCAGAAGACGGCCGAGTTGG
AACTGGCGCTGCACCGGTTGAAGGAGACGCAGGACCAACTGGTGGTGCAGGAGAAAATGGCGTCGCTGGGCGCGCTGACC
GCCGGGGTGGCGCACGAGATCAAGAATCCGCTCAACTTCGTCACTAATTTTGCGGTGCTCTCGGTGGACATGATGAAGGA
AGTACTGGAGTTGATCGCGCCGGTGCGAGCGCAGATGGCGCCGAAAGACGGCGAGTACCTGGACGATTTGTTAAGCGACC
TGACCGGCAACCTGGACCGGATCCGCGACCACGGCAAACGCGCCGACAGCATCGTGCGGGGGATGCTGGCGCACTCGCGC
GGGGGCAGCGGGCAGCGCGAGGAGATCGATTTGAACGTGCTGGTGGCGGAGGCGGTGAACCTGGCGTATCACGGCCTGCG
GGCGCAGGATCCGGCCTTCAATATCACGCTGGAATCGGAGTATGACGGCAACATTCCGCCGGTTCATGTGGTGCCGCAGG
ATTTGAGCCGCGTGATCCTGAACATCGCCAACAACGGCTGTTACGCGGCGCATCAACGCAAGCTGAAAGCGGGCGACGGA
TACCGCCCGACGCTGCGGACCTCGACCGCGCAGACCGCCGGCACGGTGGAGATCCGCATTCGGGACAACGGCACTGGAAT
TCCGGCGGCGGTGCTGCAGAAGATCTTCAACCCGTTTTTTACGACTAAGCCGACGGGGCAAGGTACCGGGTTGGGGCTTT
CCCTCAGTTACCAGATAGTTGTGGAACAATTAAAGGGGACGGTGAAAGTGCGGTCGAAGGAAAATGAATTCACCGAGTTT
CAGATCAGTCTGCCGAAATAA

Upstream 100 bases:

>100_bases
AGGCGCTGGACGCCGGCTGCGACGATTACGACACCAAACCGATCGAGCTGCCGCGCCTGTTGGAGAAGATGCGGCGGCTG
CTGGGCGAAGCGCCGAAGCC

Downstream 100 bases:

>100_bases
ACCGGCACAAGGTGAGATCGTGCCGTGGCAAGCCCCCCGGAAAGGGATGAAAACTTCCGTTTCCCGCTATCGGGGGCCGT
TGACAACCTATAATCTCTCG

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MSGELTGEALQKLRHDLRTPINHILGYTDMLVEDAAEIGISAFVEPLRKIRAGGRTLLELIQSSLGEGMLAVNAEAMAAF
ESRFRSRAQTLLISARELEEEFQRAASEDARTDIQRVVAALERLIAMSSGTGESEDAAPPETERVALPDGRGSLGLESGG
RILIAEDNPANRDILRRRLEKDGHVVTETQDGREALEQLERGDFDLLLLDILMPRLDGFETLAYIRRNERFHDLPVIMIS
ALDEIQSVVRCIEMGAEDYLPKPIDPVLLRARIGASLEKKRLRDRERQKTAELELALHRLKETQDQLVVQEKMASLGALT
AGVAHEIKNPLNFVTNFAVLSVDMMKEVLELIAPVRAQMAPKDGEYLDDLLSDLTGNLDRIRDHGKRADSIVRGMLAHSR
GGSGQREEIDLNVLVAEAVNLAYHGLRAQDPAFNITLESEYDGNIPPVHVVPQDLSRVILNIANNGCYAAHQRKLKAGDG
YRPTLRTSTAQTAGTVEIRIRDNGTGIPAAVLQKIFNPFFTTKPTGQGTGLGLSLSYQIVVEQLKGTVKVRSKENEFTEF
QISLPK

Sequences:

>Translated_566_residues
MSGELTGEALQKLRHDLRTPINHILGYTDMLVEDAAEIGISAFVEPLRKIRAGGRTLLELIQSSLGEGMLAVNAEAMAAF
ESRFRSRAQTLLISARELEEEFQRAASEDARTDIQRVVAALERLIAMSSGTGESEDAAPPETERVALPDGRGSLGLESGG
RILIAEDNPANRDILRRRLEKDGHVVTETQDGREALEQLERGDFDLLLLDILMPRLDGFETLAYIRRNERFHDLPVIMIS
ALDEIQSVVRCIEMGAEDYLPKPIDPVLLRARIGASLEKKRLRDRERQKTAELELALHRLKETQDQLVVQEKMASLGALT
AGVAHEIKNPLNFVTNFAVLSVDMMKEVLELIAPVRAQMAPKDGEYLDDLLSDLTGNLDRIRDHGKRADSIVRGMLAHSR
GGSGQREEIDLNVLVAEAVNLAYHGLRAQDPAFNITLESEYDGNIPPVHVVPQDLSRVILNIANNGCYAAHQRKLKAGDG
YRPTLRTSTAQTAGTVEIRIRDNGTGIPAAVLQKIFNPFFTTKPTGQGTGLGLSLSYQIVVEQLKGTVKVRSKENEFTEF
QISLPK
>Mature_565_residues
SGELTGEALQKLRHDLRTPINHILGYTDMLVEDAAEIGISAFVEPLRKIRAGGRTLLELIQSSLGEGMLAVNAEAMAAFE
SRFRSRAQTLLISARELEEEFQRAASEDARTDIQRVVAALERLIAMSSGTGESEDAAPPETERVALPDGRGSLGLESGGR
ILIAEDNPANRDILRRRLEKDGHVVTETQDGREALEQLERGDFDLLLLDILMPRLDGFETLAYIRRNERFHDLPVIMISA
LDEIQSVVRCIEMGAEDYLPKPIDPVLLRARIGASLEKKRLRDRERQKTAELELALHRLKETQDQLVVQEKMASLGALTA
GVAHEIKNPLNFVTNFAVLSVDMMKEVLELIAPVRAQMAPKDGEYLDDLLSDLTGNLDRIRDHGKRADSIVRGMLAHSRG
GSGQREEIDLNVLVAEAVNLAYHGLRAQDPAFNITLESEYDGNIPPVHVVPQDLSRVILNIANNGCYAAHQRKLKAGDGY
RPTLRTSTAQTAGTVEIRIRDNGTGIPAAVLQKIFNPFFTTKPTGQGTGLGLSLSYQIVVEQLKGTVKVRSKENEFTEFQ
ISLPK

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=32.5842696629214, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790436, Length=262, Percent_Identity=29.3893129770992, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=36.1344537815126, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=34.453781512605, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=106, Percent_Identity=37.7358490566038, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786784, Length=113, Percent_Identity=31.858407079646, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=30.8333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=33.6, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=134, Percent_Identity=32.089552238806, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789809, Length=125, Percent_Identity=31.2, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788394, Length=142, Percent_Identity=32.3943661971831, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62536; Mature: 62405

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGELTGEALQKLRHDLRTPINHILGYTDMLVEDAAEIGISAFVEPLRKIRAGGRTLLEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IQSSLGEGMLAVNAEAMAAFESRFRSRAQTLLISARELEEEFQRAASEDARTDIQRVVAA
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LERLIAMSSGTGESEDAAPPETERVALPDGRGSLGLESGGRILIAEDNPANRDILRRRLE
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
KDGHVVTETQDGREALEQLERGDFDLLLLDILMPRLDGFETLAYIRRNERFHDLPVIMIS
CCCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHH
ALDEIQSVVRCIEMGAEDYLPKPIDPVLLRARIGASLEKKRLRDRERQKTAELELALHRL
HHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KETQDQLVVQEKMASLGALTAGVAHEIKNPLNFVTNFAVLSVDMMKEVLELIAPVRAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKDGEYLDDLLSDLTGNLDRIRDHGKRADSIVRGMLAHSRGGSGQREEIDLNVLVAEAVN
CCCCHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHH
LAYHGLRAQDPAFNITLESEYDGNIPPVHVVPQDLSRVILNIANNGCYAAHQRKLKAGDG
HHHHCCCCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
YRPTLRTSTAQTAGTVEIRIRDNGTGIPAAVLQKIFNPFFTTKPTGQGTGLGLSLSYQIV
CCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCHHCCCCCCCCCCCCEEEHHHHHH
VEQLKGTVKVRSKENEFTEFQISLPK
HHHHHCCEEEECCCCCCEEEEEECCC
>Mature Secondary Structure 
SGELTGEALQKLRHDLRTPINHILGYTDMLVEDAAEIGISAFVEPLRKIRAGGRTLLEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IQSSLGEGMLAVNAEAMAAFESRFRSRAQTLLISARELEEEFQRAASEDARTDIQRVVAA
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LERLIAMSSGTGESEDAAPPETERVALPDGRGSLGLESGGRILIAEDNPANRDILRRRLE
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
KDGHVVTETQDGREALEQLERGDFDLLLLDILMPRLDGFETLAYIRRNERFHDLPVIMIS
CCCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHH
ALDEIQSVVRCIEMGAEDYLPKPIDPVLLRARIGASLEKKRLRDRERQKTAELELALHRL
HHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KETQDQLVVQEKMASLGALTAGVAHEIKNPLNFVTNFAVLSVDMMKEVLELIAPVRAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKDGEYLDDLLSDLTGNLDRIRDHGKRADSIVRGMLAHSRGGSGQREEIDLNVLVAEAVN
CCCCHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHH
LAYHGLRAQDPAFNITLESEYDGNIPPVHVVPQDLSRVILNIANNGCYAAHQRKLKAGDG
HHHHCCCCCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
YRPTLRTSTAQTAGTVEIRIRDNGTGIPAAVLQKIFNPFFTTKPTGQGTGLGLSLSYQIV
CCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCHHCCCCCCCCCCCCEEEHHHHHH
VEQLKGTVKVRSKENEFTEFQISLPK
HHHHHCCEEEECCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]