Click here to switch to the map view.

The map label for this gene is ftsY [H]

Identifier: 116623313

GI number: 116623313

Start: 5345326

End: 5346276

Strand: Direct

Name: ftsY [H]

Synonym: Acid_4221

Alternate gene names: 116623313

Gene position: 5345326-5346276 (Clockwise)

Preceding gene: 116623309

Following gene: 116623314

Centisome position: 53.64

GC content: 63.93

Gene sequence:

>951_bases
ATGATCCAAACCCTATTCGGCTCCGTTGAACAGGAACCCAGCCTACTCGAAAAACTCAAGAGCGGCGTGCAAAAGACCCG
CGCCGGACTGGTGACCGCGCTCGAGGACGCCCTTCAGGGCAAGAAGGAAATCGACGCCGACCTGCTCGACGAGCTCGAAT
TCACGCTCATCTCCGCCGATATCGGCGTCGCCACCACCAGTGAAATCCTGGAAAGCATCCGCCAGCGCGTGGAACGCCAC
CAGCTTGCCGACGCCGGCGAATTGAAGGGCCTCATCCGCGAGCGCCTGCTCGAAATCCTCCAGGCCAGCGAACGCGCCCC
GGCACGCGTCGCGGAGCCGCCCGCCGTAGTCCTGGTGGTCGGCGTCAACGGCGCCGGCAAGACCACCACCATCGGCAAAC
TCGCTCACCGCTTCAAGAACGAGCAGCGTTCCGTGCTGCTCTGCGCTGCCGATACCTTCCGCGCCGCCGCCATCGAACAG
CTGGAAATCTGGGGCGAGCGCACCGGCACCCAGGTGATCCGCCAGAAGCCGGGCAGCGACCCGAGCGCGGTTCTGTTCGA
CGCCGTGACCGCCGCCAAATCGCGCAAGGTGGATTACGTCATCGTGGACACCGCCGGCCGCCTCCAGACCAAGGAACACC
TGATGCTGGAGCTGGAAAAGATGAACCGCACGGCCCGCAAGGTGATTCCCGATGCGCCCCACGAAGTCCTGCTGGTGCTG
GACGCGACCACCGGCCAGAACGGCCTGGAACAGGCGCGCAAATTCACCGGCAGCTCCGGCGTCACCGGGATCGTGCTCAC
GAAACTCGACGGCACCGCCAAGGGCGGCATCGTGGTTGCGATCGCGCGCGAGCTGAACCTGCCCATTCGCTACATCGGAG
TCGGCGAAAAGATTGAGGATCTGCTGCCGTTCGACGGCGAAAAGTTCATCGAGTCCCTCTTCGAAAAATGA

Upstream 100 bases:

>100_bases
AATTTTCATCATTCCCATGTTTTCAACCACTTCCCTGATTCTCGTGACCAGAGTCTGGTCACGGAGACGCTTGCCCCCGC
TGCTAAAATGAAAGCATCAC

Downstream 100 bases:

>100_bases
GCTCTTCCTACATGCGCGAAGCGCTGGACCTGGCGCGAAAAGGCCGGTCGCTGGCGAGCCCCAATCCTCTGGTGGGCGCC
GTCATCGTCCGCGACGGCAA

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIQTLFGSVEQEPSLLEKLKSGVQKTRAGLVTALEDALQGKKEIDADLLDELEFTLISADIGVATTSEILESIRQRVERH
QLADAGELKGLIRERLLEILQASERAPARVAEPPAVVLVVGVNGAGKTTTIGKLAHRFKNEQRSVLLCAADTFRAAAIEQ
LEIWGERTGTQVIRQKPGSDPSAVLFDAVTAAKSRKVDYVIVDTAGRLQTKEHLMLELEKMNRTARKVIPDAPHEVLLVL
DATTGQNGLEQARKFTGSSGVTGIVLTKLDGTAKGGIVVAIARELNLPIRYIGVGEKIEDLLPFDGEKFIESLFEK

Sequences:

>Translated_316_residues
MIQTLFGSVEQEPSLLEKLKSGVQKTRAGLVTALEDALQGKKEIDADLLDELEFTLISADIGVATTSEILESIRQRVERH
QLADAGELKGLIRERLLEILQASERAPARVAEPPAVVLVVGVNGAGKTTTIGKLAHRFKNEQRSVLLCAADTFRAAAIEQ
LEIWGERTGTQVIRQKPGSDPSAVLFDAVTAAKSRKVDYVIVDTAGRLQTKEHLMLELEKMNRTARKVIPDAPHEVLLVL
DATTGQNGLEQARKFTGSSGVTGIVLTKLDGTAKGGIVVAIARELNLPIRYIGVGEKIEDLLPFDGEKFIESLFEK
>Mature_316_residues
MIQTLFGSVEQEPSLLEKLKSGVQKTRAGLVTALEDALQGKKEIDADLLDELEFTLISADIGVATTSEILESIRQRVERH
QLADAGELKGLIRERLLEILQASERAPARVAEPPAVVLVVGVNGAGKTTTIGKLAHRFKNEQRSVLLCAADTFRAAAIEQ
LEIWGERTGTQVIRQKPGSDPSAVLFDAVTAAKSRKVDYVIVDTAGRLQTKEHLMLELEKMNRTARKVIPDAPHEVLLVL
DATTGQNGLEQARKFTGSSGVTGIVLTKLDGTAKGGIVVAIARELNLPIRYIGVGEKIEDLLPFDGEKFIESLFEK

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=286, Percent_Identity=28.6713286713287, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI226371618, Length=198, Percent_Identity=34.8484848484849, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI23308697, Length=303, Percent_Identity=28.3828382838284, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI295424842, Length=303, Percent_Identity=28.3828382838284, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI89061728, Length=134, Percent_Identity=35.0746268656716, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1789874, Length=307, Percent_Identity=51.1400651465798, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1788963, Length=268, Percent_Identity=34.3283582089552, Blast_Score=159, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=272, Percent_Identity=27.5735294117647, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI193206261, Length=325, Percent_Identity=29.2307692307692, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=281, Percent_Identity=30.9608540925267, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320498, Length=217, Percent_Identity=28.110599078341, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17647949, Length=271, Percent_Identity=30.9963099630996, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24641198, Length=327, Percent_Identity=27.217125382263, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 34335; Mature: 34335

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTLFGSVEQEPSLLEKLKSGVQKTRAGLVTALEDALQGKKEIDADLLDELEFTLISAD
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHEEEECC
IGVATTSEILESIRQRVERHQLADAGELKGLIRERLLEILQASERAPARVAEPPAVVLVV
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GVNGAGKTTTIGKLAHRFKNEQRSVLLCAADTFRAAAIEQLEIWGERTGTQVIRQKPGSD
ECCCCCCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PSAVLFDAVTAAKSRKVDYVIVDTAGRLQTKEHLMLELEKMNRTARKVIPDAPHEVLLVL
CHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DATTGQNGLEQARKFTGSSGVTGIVLTKLDGTAKGGIVVAIARELNLPIRYIGVGEKIED
ECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCHHHHH
LLPFDGEKFIESLFEK
HCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIQTLFGSVEQEPSLLEKLKSGVQKTRAGLVTALEDALQGKKEIDADLLDELEFTLISAD
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHEEEECC
IGVATTSEILESIRQRVERHQLADAGELKGLIRERLLEILQASERAPARVAEPPAVVLVV
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GVNGAGKTTTIGKLAHRFKNEQRSVLLCAADTFRAAAIEQLEIWGERTGTQVIRQKPGSD
ECCCCCCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PSAVLFDAVTAAKSRKVDYVIVDTAGRLQTKEHLMLELEKMNRTARKVIPDAPHEVLLVL
CHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DATTGQNGLEQARKFTGSSGVTGIVLTKLDGTAKGGIVVAIARELNLPIRYIGVGEKIED
ECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCHHHHH
LLPFDGEKFIESLFEK
HCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]