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The map label for this gene is 116623303

Identifier: 116623303

GI number: 116623303

Start: 5335934

End: 5337226

Strand: Reverse

Name: 116623303

Synonym: Acid_4210

Alternate gene names: NA

Gene position: 5337226-5335934 (Counterclockwise)

Preceding gene: 116623306

Following gene: 116623292

Centisome position: 53.56

GC content: 62.03

Gene sequence:

>1293_bases
ATGACGCGACGCGAATCCCTGCAACTCATGGCCGCCGGGGCAGCGGCCAGTAGCGCAATCCGCACTCTCACGGCCGCCGG
CGGCGATGCGGACCGCGAGGCGCGCATGAAATGGTGGCATGAAGCCCGTTTCGGGATGTTCATCCACTGGGGGCTGTACA
GCGTTCTGGGGCGCCACGAATGGGCCATGGAGAACGAAGGTATCCCGGTGGCCGAATACGAGCAGATTGCCAAGCGTTTC
AAGCCGAAGCCGAACGCGGCGCGCGATTGGGCCAAACTCGCCAAAGCGGCCGGCCAGAAATACATGGTGATGACGACCAA
GCATCACGAAGGCTTCTGCCACTTCGATTCCAAGCTGACCGATTATTGCGCTCCCAAACAGGGGCCGGGCCGCGACCTGG
TCCGGGAATACGTGGATGCAGCGCGTGCCGAGGGACTGCGCGTGGGCTTCTACTACTCGCTGATGGACTGGCACCACCCG
GATGGCGCGCGCTGCGCGACCGACGAGGCGGCGCGGGTGCGCTTCGTGAATTACATCCACGGGCAGATCCGCGAGTTGCT
GACGAACTACGGCAAGATCGATATCCTCTGGTACGACGTGGCGTGGCCGCTCGATGCCAGGGGCTGGGAATCGGAAAAGA
TGAACGCGATGGTTTATCAACTGCAGCCCGGGATCATCGTGAACGGCCGCAATAAACTGCCGGGGGATTTCGCCACTCCG
GAACAGAAGATCGAGGCAACCAAAGGCGCCTGGGAAAGCTGCATGACGATGAATGGCAGCTGGGGCTACCAGCGCGCCGA
CAACGACTGGAAGACGCCGAAGACGATTGTGCGCAACCTGATCACCTGCGCGCACGACACCGGCAATTACCTGCTCAATA
TCGGGCCGAAGGCGGATGGCTCCGTTCCCGAGGAATCGGTGAAGATCATGACGCAGGTGGGTGAATGGATGTCGAAGAGC
GGCAAGTCGATCTACGATACCGACGTCTGCCAGCCGCGCCGGTCCGCCTTCGCGAGCTTTACGCGCAAGGGCAACACGCT
GTATATGCACGTTCACTACTGGCCGGGCGAGACGGTGGCGCTGGCAGGGCTGATGAACAAGGTACAGTCCGCGCACCTGC
TGGCGAGCGGCAGGGCGGTTAAGTTCGAGCAGGATAGATTCAGGGTACGGTTCACGGGGCTGCCGGAGAATGCGCCGGAT
AATCCGGTCACCACGCTGGCCATCGAGTGCGACGGCGAGCCGCGGCAGGACACGGATTTCGTGAGGAAAGAGCATTTGCG
GGATAAGGCGTAG

Upstream 100 bases:

>100_bases
AACGCACCATACTTCATTGTACCGGCAAGCATTTGCGTAACTTTACTTTACCGCTAAACAATGGCGTGTTATGCTGTTGC
GTCAGGAGCGAAAGAAAGCG

Downstream 100 bases:

>100_bases
CTGCGAGAAAAGTGCAGCCTCGCCCAGCGATCGACCTTAAGGCCGAAGGCGCTCGGCGGCGATGGCGGCTTGGCCCAGGG
CAAGACCGCCGTCGTTGGGG

Product: alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Coagulation Factor 5/8 Type Domain Protein; Calx-Beta Domain-Containing Protein; Exported Alpha-L-Fucosidase Protein; Alpha-L-Fucosidase Protein; Lipoprotein; Exporte Hydrolase; Alpha-L-Fucosidase Family Protein; Alpha-L-Fucosidase-Like Protein; Glycoside Hydrolase Family Alpha-L-Fucosidase; Ig Domain-Containing; Twin-Arginine Translocation Pathway Signal; Fucosidase; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; Exported Fucosidase; Glycoside Hydrolase

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTRRESLQLMAAGAAASSAIRTLTAAGGDADREARMKWWHEARFGMFIHWGLYSVLGRHEWAMENEGIPVAEYEQIAKRF
KPKPNAARDWAKLAKAAGQKYMVMTTKHHEGFCHFDSKLTDYCAPKQGPGRDLVREYVDAARAEGLRVGFYYSLMDWHHP
DGARCATDEAARVRFVNYIHGQIRELLTNYGKIDILWYDVAWPLDARGWESEKMNAMVYQLQPGIIVNGRNKLPGDFATP
EQKIEATKGAWESCMTMNGSWGYQRADNDWKTPKTIVRNLITCAHDTGNYLLNIGPKADGSVPEESVKIMTQVGEWMSKS
GKSIYDTDVCQPRRSAFASFTRKGNTLYMHVHYWPGETVALAGLMNKVQSAHLLASGRAVKFEQDRFRVRFTGLPENAPD
NPVTTLAIECDGEPRQDTDFVRKEHLRDKA

Sequences:

>Translated_430_residues
MTRRESLQLMAAGAAASSAIRTLTAAGGDADREARMKWWHEARFGMFIHWGLYSVLGRHEWAMENEGIPVAEYEQIAKRF
KPKPNAARDWAKLAKAAGQKYMVMTTKHHEGFCHFDSKLTDYCAPKQGPGRDLVREYVDAARAEGLRVGFYYSLMDWHHP
DGARCATDEAARVRFVNYIHGQIRELLTNYGKIDILWYDVAWPLDARGWESEKMNAMVYQLQPGIIVNGRNKLPGDFATP
EQKIEATKGAWESCMTMNGSWGYQRADNDWKTPKTIVRNLITCAHDTGNYLLNIGPKADGSVPEESVKIMTQVGEWMSKS
GKSIYDTDVCQPRRSAFASFTRKGNTLYMHVHYWPGETVALAGLMNKVQSAHLLASGRAVKFEQDRFRVRFTGLPENAPD
NPVTTLAIECDGEPRQDTDFVRKEHLRDKA
>Mature_429_residues
TRRESLQLMAAGAAASSAIRTLTAAGGDADREARMKWWHEARFGMFIHWGLYSVLGRHEWAMENEGIPVAEYEQIAKRFK
PKPNAARDWAKLAKAAGQKYMVMTTKHHEGFCHFDSKLTDYCAPKQGPGRDLVREYVDAARAEGLRVGFYYSLMDWHHPD
GARCATDEAARVRFVNYIHGQIRELLTNYGKIDILWYDVAWPLDARGWESEKMNAMVYQLQPGIIVNGRNKLPGDFATPE
QKIEATKGAWESCMTMNGSWGYQRADNDWKTPKTIVRNLITCAHDTGNYLLNIGPKADGSVPEESVKIMTQVGEWMSKSG
KSIYDTDVCQPRRSAFASFTRKGNTLYMHVHYWPGETVALAGLMNKVQSAHLLASGRAVKFEQDRFRVRFTGLPENAPDN
PVTTLAIECDGEPRQDTDFVRKEHLRDKA

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI119360348, Length=416, Percent_Identity=28.8461538461538, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI40068512, Length=323, Percent_Identity=32.1981424148607, Blast_Score=145, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71997700, Length=399, Percent_Identity=26.5664160401003, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24662717, Length=334, Percent_Identity=29.940119760479, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI78706642, Length=334, Percent_Identity=29.940119760479, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 48689; Mature: 48557

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRESLQLMAAGAAASSAIRTLTAAGGDADREARMKWWHEARFGMFIHWGLYSVLGRHE
CCCHHHHHHEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHCCCH
WAMENEGIPVAEYEQIAKRFKPKPNAARDWAKLAKAAGQKYMVMTTKHHEGFCHFDSKLT
HCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCHHH
DYCAPKQGPGRDLVREYVDAARAEGLRVGFYYSLMDWHHPDGARCATDEAARVRFVNYIH
HHCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
GQIRELLTNYGKIDILWYDVAWPLDARGWESEKMNAMVYQLQPGIIVNGRNKLPGDFATP
HHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCC
EQKIEATKGAWESCMTMNGSWGYQRADNDWKTPKTIVRNLITCAHDTGNYLLNIGPKADG
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
SVPEESVKIMTQVGEWMSKSGKSIYDTDVCQPRRSAFASFTRKGNTLYMHVHYWPGETVA
CCCHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHH
LAGLMNKVQSAHLLASGRAVKFEQDRFRVRFTGLPENAPDNPVTTLAIECDGEPRQDTDF
HHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCHHH
VRKEHLRDKA
HHHHHHCCCC
>Mature Secondary Structure 
TRRESLQLMAAGAAASSAIRTLTAAGGDADREARMKWWHEARFGMFIHWGLYSVLGRHE
CCHHHHHHEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHCCCH
WAMENEGIPVAEYEQIAKRFKPKPNAARDWAKLAKAAGQKYMVMTTKHHEGFCHFDSKLT
HCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCHHH
DYCAPKQGPGRDLVREYVDAARAEGLRVGFYYSLMDWHHPDGARCATDEAARVRFVNYIH
HHCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
GQIRELLTNYGKIDILWYDVAWPLDARGWESEKMNAMVYQLQPGIIVNGRNKLPGDFATP
HHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCC
EQKIEATKGAWESCMTMNGSWGYQRADNDWKTPKTIVRNLITCAHDTGNYLLNIGPKADG
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
SVPEESVKIMTQVGEWMSKSGKSIYDTDVCQPRRSAFASFTRKGNTLYMHVHYWPGETVA
CCCHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHH
LAGLMNKVQSAHLLASGRAVKFEQDRFRVRFTGLPENAPDNPVTTLAIECDGEPRQDTDF
HHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCEEEEEEEECCCCCCCHHH
VRKEHLRDKA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA