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The map label for this gene is metH [H]

Identifier: 116623277

GI number: 116623277

Start: 5305373

End: 5308930

Strand: Direct

Name: metH [H]

Synonym: Acid_4184

Alternate gene names: 116623277

Gene position: 5305373-5308930 (Clockwise)

Preceding gene: 116623270

Following gene: 116623278

Centisome position: 53.24

GC content: 63.01

Gene sequence:

>3558_bases
ATGACAAATTTCCTGGAGCGTCAAAAGGCGCTCAACGACAGCCTGGAACAACGTGTCCTCGTCCTCGACGGGGCCATGGG
CACCATGATTCACCAAGCGCCGCTATCTATCGAAACCGACTACCTGGGCCGGGAAAATTGTCCGGAAATCCTCAACGTCA
CGCGCCCCGACGTGATTCAGGATATCCACCGCCAGTACCTCGAAGCCGGCGCCGATATCATTGAGACCAACACCTTTGGC
GGAACCCGGATCGCGCTCGCGGACAACAAACTCGAAGAGCGCGCCTACGAGCTTAATTTCGCCGCCGCAAAACTCGCGCG
CGAAGTGGCCGACCAGTTCTCGACCGCGGCGAAACCCCGCTTCGTTGCCGGCTCCATCGGCCCCACGAACAAAGACCTCA
ATATCACCGGCAGCACCACTTTCCCCGAAATCAAGGCCGCCTATTACGAGCAGGCCAAGGGACTCGTGGAAGGCGGCGCG
GATTACCTTCTGATCGAAACCTGCTTCGATACCGGCAGCCTCAAGGCCGGACTGGTCGCGGTCGAACAGTTGGGCCGCGA
ACTCGCCATCCAGATTCCCGTAGTCGCTTCCGTGACCATCGAGCGCACCGGCACCATGCTCGGAGGGCAGCAGATCGACG
CCCTCTACGCCTCCATCGGCAATCACGAGTTGCTGGGCGTAGGCATGAACTGCGCCACCGGTCCCGACCTGATGACGGAC
CACATCCGCACGCTCAACGAAATGTCGGCCCACCGGATTTCGTGCTATCCGAATGCCGGCCTGCCCAATGCCGAAGGCAA
GTTCGGGGAGACCCCCGATTCGCTGGCGGCACAGCTCGAGAAGTTCGCCAACCAGGGCTGGTTGAATTTCGTCGGCGGCT
GCTGCGGCACCACGCCGGCGCACATTCAGGCCATCGCGCAGATGATCCAGGGCAAGCGCCCGCGCGCCACTCCGGCCAGC
AAGCACCGCGCCTACTACTCGGGCATCGACCTAGTGGAAGCCGAGGACAGCAACCGCCCCCTGCTGGTCGGCGAGCGCAC
CAACGTGATCGGCTCGCGCCTTTTCAAGAACCTGATCGCCGACGAGAAGTGGGAAGAGGCCACCGATATCGCGCGCCGCC
AGGTGCGCAACGGCGCGCACGTGATTGACGTTTGCCTGCAGAGCACGGACCGTGAAGAGCTCGAAGACATCCGCCCCTTC
TACGAGAAGCTGATCCGCAAGATCAAAGCGCCGATCATGATCGACACCACCGACCCCAAGGCGGTGGAACTCGCGCTTAC
CTACTGCCAGGGTAAGAGCATCATCAACTCCGTGAACCTGGAGGATGGCGAAGAGAAGTTCGAGCGCCTGTGCCCGATCG
CGAAGCTCTACGGCGCTGCACTCGTGGTCGGCTCCATCGACGAAGATAAACTGCAGGCGCAGGCCTTCACGCGCGAACGC
AAAGTGGCCGTCGCGGAGCGCTCTTATCGGTTGCTCACCGAAAAGTACGGCATCCCCGGCGAGGACATCATCATCGACCC
GCTGGTCTTCCCCTGCGCCACCGGCGACGTCAACTATATCGGCGGAGCGGTGGAAACCATCGAAGGCATCCGGCTCGTCA
AGCAAGCGCTGCCCTACGCCAAGACCGTGCTCGGCATTTCGAACATCAGCTTCGGCCTGCCCGCCGCGGCACGCGAAGTG
GTCAACTCGGTCTTCCTCTACTACTGCACTAAGGCGGGGCTCGATCTCGCCATCGTCAACGCGGAGAAGCTAGAGCGTTT
CGCCTCCATTCCCGAAGAAGAGCGCCGCCTCGCCGAGCACCTGCTCTTCAACACGCCGCCCGCTGGGGCCGAGGACGAAT
CGCTGCGCACCGCGGCCGAGGACTGGCGCGCGCAATCGCCCGAGCAGAAGGCAGCCATCAACCAATTCCACATTGCCGCC
ATCGCGGAGCATTTCCGCAAGGCCGGCGCGCGCGTCAAGAAGGCGGCCGCCGATATGCCGTTGGATCAGCGCCTGGCCAA
CTACATCATCGAAGGCACCAAGGACGGACTGATCGCCGATCTCGATCGCAAGCGCGCGGAGGGCGCCACACCGCTCGAAA
TCATCAACGGTCCGCTGATGGCGGGGATGAGCGAGGTCGGCCGCCTGTTTAACAATAATGAGCTGATCGTCGCCGAGGTG
CTGCAATCCGCCGAGGCGATGAAGGCCGCGGTCAACCACCTCGAGCAGTTCATGGAGAAGGCCGACACCGCCGCGCGCGG
CAAGGTGCTTCTCGCCACCGTGAAGGGCGACGTCCACGATATCGGCAAGAACCTGGTGGAGATCATCCTCGCCAACAATG
GCTACGAGGTGATCAACCTGGGCATCAAGGTGCCGCCCGATGTGCTGATTCAGGCCTTCCGCGAACATATGCCCGACGCC
ATTGGCCTCTCCGGCCTGCTGGTGAAGAGCACGCAGCAGATGGTGATCACCGCGACCGACCTCAAGGCCGCCGGCATCGA
TGTGCCGCTCTTGGTGGGCGGCGCCGCACTTTCCGAGAAATTCACGCGCACCAAGATCGGCCCCGCTTATTCGGAGGCCG
TTTGTTATGCCAAGGACGCGATGACCGGCCTCAGCCTGATGAATCGCCTGATGGATCCGGCGGAGCGCGAAGCCCTGATC
GCCACCAGCACCACGCTGGAGGCGCCCGCCGCCGTGGAAGCGCCCGCCGAGCCGCTCGGCCCGCTGAGCACGCGCCGCAG
CCGCAAGGTCCGAACCGAATTGCCGGTCCCGCCCGCTCCCTATCTGGAGCGCAAGGTGCGCGACGTGCCGAATCTCGCCG
ACGTATGGAGCTACATCAACCCGTTCATGATTTACGGGCGCCACCTCGGCTACAAAGGCAACTTCGAAAAGGCGCTCGCC
GAACATGAGGAGAAGGCGCTCGAGTTGTTCCACAACGTGGAGGAACTCAAGCACGAGGCCGCGCAGTTCATGCACGTGAA
GGCCGTCTGGCAATTCTTCGAGGCCGAGCGTGACGGGAACGCGATCCACCTGTTCGCGCCCGGCGGGGCATCGCCCATCC
ACACCTTCCGCTTCGGCCGCCAGCGCCGCGAAGACGGACTCTGCCTCAGCGATTACATCCTGGACTCCCCCGACGGCAAG
CGCGATCACCTCGCCCTGTTCGTCACCACAGCGGGGGCGGGCATCCGCGAACGCAGCGAGCAATGGAAGAAGGCCGGCGA
GTTCTTCAAGGCGCACGCCATCCAGGCGCTGGCCATCGAAACCGCTGAAGCCACTGCCGAGTGGCTCCACCGCCGCATTC
GCGAAGACTGGGGCTTCCCCGATCCGCCGACCACCACGATGCACGATCGCTTCACTTCGAAATATCACGGCAAGCGCTAC
AGCTTCGGCTACCCGGCCTGCCCCAATCTCGACGATCAACAGGGAGTGTGGAAGCTGATCAATCCCGACGATATCGGAGT
GAAGCTCACCGAAGGCATGATGATGGAGCCTGAGGCCAGCGTCAGTGCCATCGTCTTTCACCATCCCGATTGCGCCTACT
TCACCGCCGACGAAGGCGAATCGGAGGCGACGGCGTAA

Upstream 100 bases:

>100_bases
CTCATTATCTGTCCTGATGTTGTCATATTTGACAACGCAGGTCAACCGGCGCCGTGAACCCTCTTCCCCGCCCTGCTAAA
ATCAAGAAAGCACATCCCCT

Downstream 100 bases:

>100_bases
CAGCGGCGATGCCCACCTGGAATGCGTCTCAGTACCTGAAATTCGCGGAAGAGCGCACCCAGCCCTGCCGCGACCTGACC
GCGCGCGTGCCGCTGGCGCA

Product: methionine synthase (B12-dependent)

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1185; Mature: 1184

Protein sequence:

>1185_residues
MTNFLERQKALNDSLEQRVLVLDGAMGTMIHQAPLSIETDYLGRENCPEILNVTRPDVIQDIHRQYLEAGADIIETNTFG
GTRIALADNKLEERAYELNFAAAKLAREVADQFSTAAKPRFVAGSIGPTNKDLNITGSTTFPEIKAAYYEQAKGLVEGGA
DYLLIETCFDTGSLKAGLVAVEQLGRELAIQIPVVASVTIERTGTMLGGQQIDALYASIGNHELLGVGMNCATGPDLMTD
HIRTLNEMSAHRISCYPNAGLPNAEGKFGETPDSLAAQLEKFANQGWLNFVGGCCGTTPAHIQAIAQMIQGKRPRATPAS
KHRAYYSGIDLVEAEDSNRPLLVGERTNVIGSRLFKNLIADEKWEEATDIARRQVRNGAHVIDVCLQSTDREELEDIRPF
YEKLIRKIKAPIMIDTTDPKAVELALTYCQGKSIINSVNLEDGEEKFERLCPIAKLYGAALVVGSIDEDKLQAQAFTRER
KVAVAERSYRLLTEKYGIPGEDIIIDPLVFPCATGDVNYIGGAVETIEGIRLVKQALPYAKTVLGISNISFGLPAAAREV
VNSVFLYYCTKAGLDLAIVNAEKLERFASIPEEERRLAEHLLFNTPPAGAEDESLRTAAEDWRAQSPEQKAAINQFHIAA
IAEHFRKAGARVKKAAADMPLDQRLANYIIEGTKDGLIADLDRKRAEGATPLEIINGPLMAGMSEVGRLFNNNELIVAEV
LQSAEAMKAAVNHLEQFMEKADTAARGKVLLATVKGDVHDIGKNLVEIILANNGYEVINLGIKVPPDVLIQAFREHMPDA
IGLSGLLVKSTQQMVITATDLKAAGIDVPLLVGGAALSEKFTRTKIGPAYSEAVCYAKDAMTGLSLMNRLMDPAEREALI
ATSTTLEAPAAVEAPAEPLGPLSTRRSRKVRTELPVPPAPYLERKVRDVPNLADVWSYINPFMIYGRHLGYKGNFEKALA
EHEEKALELFHNVEELKHEAAQFMHVKAVWQFFEAERDGNAIHLFAPGGASPIHTFRFGRQRREDGLCLSDYILDSPDGK
RDHLALFVTTAGAGIRERSEQWKKAGEFFKAHAIQALAIETAEATAEWLHRRIREDWGFPDPPTTTMHDRFTSKYHGKRY
SFGYPACPNLDDQQGVWKLINPDDIGVKLTEGMMMEPEASVSAIVFHHPDCAYFTADEGESEATA

Sequences:

>Translated_1185_residues
MTNFLERQKALNDSLEQRVLVLDGAMGTMIHQAPLSIETDYLGRENCPEILNVTRPDVIQDIHRQYLEAGADIIETNTFG
GTRIALADNKLEERAYELNFAAAKLAREVADQFSTAAKPRFVAGSIGPTNKDLNITGSTTFPEIKAAYYEQAKGLVEGGA
DYLLIETCFDTGSLKAGLVAVEQLGRELAIQIPVVASVTIERTGTMLGGQQIDALYASIGNHELLGVGMNCATGPDLMTD
HIRTLNEMSAHRISCYPNAGLPNAEGKFGETPDSLAAQLEKFANQGWLNFVGGCCGTTPAHIQAIAQMIQGKRPRATPAS
KHRAYYSGIDLVEAEDSNRPLLVGERTNVIGSRLFKNLIADEKWEEATDIARRQVRNGAHVIDVCLQSTDREELEDIRPF
YEKLIRKIKAPIMIDTTDPKAVELALTYCQGKSIINSVNLEDGEEKFERLCPIAKLYGAALVVGSIDEDKLQAQAFTRER
KVAVAERSYRLLTEKYGIPGEDIIIDPLVFPCATGDVNYIGGAVETIEGIRLVKQALPYAKTVLGISNISFGLPAAAREV
VNSVFLYYCTKAGLDLAIVNAEKLERFASIPEEERRLAEHLLFNTPPAGAEDESLRTAAEDWRAQSPEQKAAINQFHIAA
IAEHFRKAGARVKKAAADMPLDQRLANYIIEGTKDGLIADLDRKRAEGATPLEIINGPLMAGMSEVGRLFNNNELIVAEV
LQSAEAMKAAVNHLEQFMEKADTAARGKVLLATVKGDVHDIGKNLVEIILANNGYEVINLGIKVPPDVLIQAFREHMPDA
IGLSGLLVKSTQQMVITATDLKAAGIDVPLLVGGAALSEKFTRTKIGPAYSEAVCYAKDAMTGLSLMNRLMDPAEREALI
ATSTTLEAPAAVEAPAEPLGPLSTRRSRKVRTELPVPPAPYLERKVRDVPNLADVWSYINPFMIYGRHLGYKGNFEKALA
EHEEKALELFHNVEELKHEAAQFMHVKAVWQFFEAERDGNAIHLFAPGGASPIHTFRFGRQRREDGLCLSDYILDSPDGK
RDHLALFVTTAGAGIRERSEQWKKAGEFFKAHAIQALAIETAEATAEWLHRRIREDWGFPDPPTTTMHDRFTSKYHGKRY
SFGYPACPNLDDQQGVWKLINPDDIGVKLTEGMMMEPEASVSAIVFHHPDCAYFTADEGESEATA
>Mature_1184_residues
TNFLERQKALNDSLEQRVLVLDGAMGTMIHQAPLSIETDYLGRENCPEILNVTRPDVIQDIHRQYLEAGADIIETNTFGG
TRIALADNKLEERAYELNFAAAKLAREVADQFSTAAKPRFVAGSIGPTNKDLNITGSTTFPEIKAAYYEQAKGLVEGGAD
YLLIETCFDTGSLKAGLVAVEQLGRELAIQIPVVASVTIERTGTMLGGQQIDALYASIGNHELLGVGMNCATGPDLMTDH
IRTLNEMSAHRISCYPNAGLPNAEGKFGETPDSLAAQLEKFANQGWLNFVGGCCGTTPAHIQAIAQMIQGKRPRATPASK
HRAYYSGIDLVEAEDSNRPLLVGERTNVIGSRLFKNLIADEKWEEATDIARRQVRNGAHVIDVCLQSTDREELEDIRPFY
EKLIRKIKAPIMIDTTDPKAVELALTYCQGKSIINSVNLEDGEEKFERLCPIAKLYGAALVVGSIDEDKLQAQAFTRERK
VAVAERSYRLLTEKYGIPGEDIIIDPLVFPCATGDVNYIGGAVETIEGIRLVKQALPYAKTVLGISNISFGLPAAAREVV
NSVFLYYCTKAGLDLAIVNAEKLERFASIPEEERRLAEHLLFNTPPAGAEDESLRTAAEDWRAQSPEQKAAINQFHIAAI
AEHFRKAGARVKKAAADMPLDQRLANYIIEGTKDGLIADLDRKRAEGATPLEIINGPLMAGMSEVGRLFNNNELIVAEVL
QSAEAMKAAVNHLEQFMEKADTAARGKVLLATVKGDVHDIGKNLVEIILANNGYEVINLGIKVPPDVLIQAFREHMPDAI
GLSGLLVKSTQQMVITATDLKAAGIDVPLLVGGAALSEKFTRTKIGPAYSEAVCYAKDAMTGLSLMNRLMDPAEREALIA
TSTTLEAPAAVEAPAEPLGPLSTRRSRKVRTELPVPPAPYLERKVRDVPNLADVWSYINPFMIYGRHLGYKGNFEKALAE
HEEKALELFHNVEELKHEAAQFMHVKAVWQFFEAERDGNAIHLFAPGGASPIHTFRFGRQRREDGLCLSDYILDSPDGKR
DHLALFVTTAGAGIRERSEQWKKAGEFFKAHAIQALAIETAEATAEWLHRRIREDWGFPDPPTTTMHDRFTSKYHGKRYS
FGYPACPNLDDQQGVWKLINPDDIGVKLTEGMMMEPEASVSAIVFHHPDCAYFTADEGESEATA

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1237, Percent_Identity=34.9232012934519, Blast_Score=642, Evalue=0.0,
Organism=Homo sapiens, GI157266337, Length=314, Percent_Identity=27.0700636942675, Blast_Score=91, Evalue=6e-18,
Organism=Escherichia coli, GI1790450, Length=1226, Percent_Identity=35.0734094616639, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1786456, Length=314, Percent_Identity=24.8407643312102, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17535405, Length=1231, Percent_Identity=34.8497156783103, Blast_Score=658, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 130140; Mature: 130008

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFLERQKALNDSLEQRVLVLDGAMGTMIHQAPLSIETDYLGRENCPEILNVTRPDVIQ
CCCHHHHHHHHHHHHHCEEEEEECCHHHHHHHCCCCEECCCCCCCCCHHHHCCCCHHHHH
DIHRQYLEAGADIIETNTFGGTRIALADNKLEERAYELNFAAAKLAREVADQFSTAAKPR
HHHHHHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FVAGSIGPTNKDLNITGSTTFPEIKAAYYEQAKGLVEGGADYLLIETCFDTGSLKAGLVA
EEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHH
VEQLGRELAIQIPVVASVTIERTGTMLGGQQIDALYASIGNHELLGVGMNCATGPDLMTD
HHHCCHHHEEEECEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
HIRTLNEMSAHRISCYPNAGLPNAEGKFGETPDSLAAQLEKFANQGWLNFVGGCCGTTPA
HHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCHH
HIQAIAQMIQGKRPRATPASKHRAYYSGIDLVEAEDSNRPLLVGERTNVIGSRLFKNLIA
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHHC
DEKWEEATDIARRQVRNGAHVIDVCLQSTDREELEDIRPFYEKLIRKIKAPIMIDTTDPK
CCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
AVELALTYCQGKSIINSVNLEDGEEKFERLCPIAKLYGAALVVGSIDEDKLQAQAFTRER
EEEEEHHHHCCCHHHHCCCCCCHHHHHHHHCHHHHHHHHHHEEECCCHHHHHHHHHHHHH
KVAVAERSYRLLTEKYGIPGEDIIIDPLVFPCATGDVNYIGGAVETIEGIRLVKQALPYA
HHHHHHHHHHHHHHHCCCCCCCEEECCEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCHH
KTVLGISNISFGLPAAAREVVNSVFLYYCTKAGLDLAIVNAEKLERFASIPEEERRLAEH
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHH
LLFNTPPAGAEDESLRTAAEDWRAQSPEQKAAINQFHIAAIAEHFRKAGARVKKAAADMP
HHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDQRLANYIIEGTKDGLIADLDRKRAEGATPLEIINGPLMAGMSEVGRLFNNNELIVAEV
HHHHHHHHHHCCCCCCCEEHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEHHHH
LQSAEAMKAAVNHLEQFMEKADTAARGKVLLATVKGDVHDIGKNLVEIILANNGYEVINL
HHHHHHHHHHHHHHHHHHHHHCHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE
GIKVPPDVLIQAFREHMPDAIGLSGLLVKSTQQMVITATDLKAAGIDVPLLVGGAALSEK
CCCCCHHHHHHHHHHHCCHHCCCCHHEEECCCCEEEEEECCCCCCCCCHHEECCHHHHHH
FTRTKIGPAYSEAVCYAKDAMTGLSLMNRLMDPAEREALIATSTTLEAPAAVEAPAEPLG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCCCCCCCC
PLSTRRSRKVRTELPVPPAPYLERKVRDVPNLADVWSYINPFMIYGRHLGYKGNFEKALA
CCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
EHEEKALELFHNVEELKHEAAQFMHVKAVWQFFEAERDGNAIHLFAPGGASPIHTFRFGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
QRREDGLCLSDYILDSPDGKRDHLALFVTTAGAGIRERSEQWKKAGEFFKAHAIQALAIE
HHCCCCCEEHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TAEATAEWLHRRIREDWGFPDPPTTTMHDRFTSKYHGKRYSFGYPACPNLDDQQGVWKLI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEC
NPDDIGVKLTEGMMMEPEASVSAIVFHHPDCAYFTADEGESEATA
CCCCCCEEECCCEEECCCCCCEEEEEECCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
TNFLERQKALNDSLEQRVLVLDGAMGTMIHQAPLSIETDYLGRENCPEILNVTRPDVIQ
CCHHHHHHHHHHHHHCEEEEEECCHHHHHHHCCCCEECCCCCCCCCHHHHCCCCHHHHH
DIHRQYLEAGADIIETNTFGGTRIALADNKLEERAYELNFAAAKLAREVADQFSTAAKPR
HHHHHHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FVAGSIGPTNKDLNITGSTTFPEIKAAYYEQAKGLVEGGADYLLIETCFDTGSLKAGLVA
EEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHH
VEQLGRELAIQIPVVASVTIERTGTMLGGQQIDALYASIGNHELLGVGMNCATGPDLMTD
HHHCCHHHEEEECEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
HIRTLNEMSAHRISCYPNAGLPNAEGKFGETPDSLAAQLEKFANQGWLNFVGGCCGTTPA
HHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCHH
HIQAIAQMIQGKRPRATPASKHRAYYSGIDLVEAEDSNRPLLVGERTNVIGSRLFKNLIA
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHHC
DEKWEEATDIARRQVRNGAHVIDVCLQSTDREELEDIRPFYEKLIRKIKAPIMIDTTDPK
CCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
AVELALTYCQGKSIINSVNLEDGEEKFERLCPIAKLYGAALVVGSIDEDKLQAQAFTRER
EEEEEHHHHCCCHHHHCCCCCCHHHHHHHHCHHHHHHHHHHEEECCCHHHHHHHHHHHHH
KVAVAERSYRLLTEKYGIPGEDIIIDPLVFPCATGDVNYIGGAVETIEGIRLVKQALPYA
HHHHHHHHHHHHHHHCCCCCCCEEECCEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCHH
KTVLGISNISFGLPAAAREVVNSVFLYYCTKAGLDLAIVNAEKLERFASIPEEERRLAEH
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHH
LLFNTPPAGAEDESLRTAAEDWRAQSPEQKAAINQFHIAAIAEHFRKAGARVKKAAADMP
HHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDQRLANYIIEGTKDGLIADLDRKRAEGATPLEIINGPLMAGMSEVGRLFNNNELIVAEV
HHHHHHHHHHCCCCCCCEEHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEHHHH
LQSAEAMKAAVNHLEQFMEKADTAARGKVLLATVKGDVHDIGKNLVEIILANNGYEVINL
HHHHHHHHHHHHHHHHHHHHHCHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE
GIKVPPDVLIQAFREHMPDAIGLSGLLVKSTQQMVITATDLKAAGIDVPLLVGGAALSEK
CCCCCHHHHHHHHHHHCCHHCCCCHHEEECCCCEEEEEECCCCCCCCCHHEECCHHHHHH
FTRTKIGPAYSEAVCYAKDAMTGLSLMNRLMDPAEREALIATSTTLEAPAAVEAPAEPLG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCCCCCCCC
PLSTRRSRKVRTELPVPPAPYLERKVRDVPNLADVWSYINPFMIYGRHLGYKGNFEKALA
CCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
EHEEKALELFHNVEELKHEAAQFMHVKAVWQFFEAERDGNAIHLFAPGGASPIHTFRFGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
QRREDGLCLSDYILDSPDGKRDHLALFVTTAGAGIRERSEQWKKAGEFFKAHAIQALAIE
HHCCCCCEEHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TAEATAEWLHRRIREDWGFPDPPTTTMHDRFTSKYHGKRYSFGYPACPNLDDQQGVWKLI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEC
NPDDIGVKLTEGMMMEPEASVSAIVFHHPDCAYFTADEGESEATA
CCCCCCEEECCCEEECCCCCCEEEEEECCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]