Click here to switch to the map view.

The map label for this gene is algU [H]

Identifier: 116623189

GI number: 116623189

Start: 5206080

End: 5206640

Strand: Direct

Name: algU [H]

Synonym: Acid_4096

Alternate gene names: 116623189

Gene position: 5206080-5206640 (Clockwise)

Preceding gene: 116623188

Following gene: 116623190

Centisome position: 52.24

GC content: 62.75

Gene sequence:

>561_bases
ATGGTCTTAGAGTGTACGGATCGGGAACTCGTGGAAGGGTGCCGGCGCGGGGAGCGCGAGGCATTCCGGGTTCTGTTTGA
GACGTACAAGGACAAGATCTACTCGATCGCACTGCGCTTCAGCGGGGACCAGGCACTGGCGATGGATATCGCGCAGGATA
CGTTCCTGAAGCTGTACAGCTCGATCGCGGATTTCCGTGGGGAATCGCAGTTCAGCACCTGGGTGTACCGGTTGGTAGTG
AACAGCTGCCTGGATCACAAGCGGAAATCGTGGCGGATGATCCCGCTGGCGGACGAGCTGCTGGCGGTGATGCGGGCGCC
GGGAGATGCGCTGCACGCGGTCATCCGGACGGAGATGAGCGAGCGGGTGCAGCGGGCTGTGGAGAAACTCCCGGAAGAGC
AGCGGATCGTGGTGGTTTTGCGGTACACGGAAGGGCTGGCGTACGAGCAGATCGCGGAAGTGATCGGGTGCTCGATGGGG
ACGGTGGCGTCGCGATTGAATCGCGCGCACAGGGCCCTGGAGAGGCGGCTGGCGAACCTGAAAGGAGCGGCGCATGTCTG
A

Upstream 100 bases:

>100_bases
GCTCCCTGACGGTCGCGGTTCGCGGTGACGGGACAGTGTGAAAGAAAGTGAGCAAATCGTGGGAAGAAGAATGGCGGTAT
GATCGTCACAGGGTAGGGCG

Downstream 100 bases:

>100_bases
TTGGCTGGAAGAACAGCTATCGCAGCATTTGAATCCGGTGAAGGCACCCGAGAAGCTCGGCGTGCGGCTGGGATTCGCGC
GCGCGACGCGGCATCAGGTT

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MVLECTDRELVEGCRRGEREAFRVLFETYKDKIYSIALRFSGDQALAMDIAQDTFLKLYSSIADFRGESQFSTWVYRLVV
NSCLDHKRKSWRMIPLADELLAVMRAPGDALHAVIRTEMSERVQRAVEKLPEEQRIVVVLRYTEGLAYEQIAEVIGCSMG
TVASRLNRAHRALERRLANLKGAAHV

Sequences:

>Translated_186_residues
MVLECTDRELVEGCRRGEREAFRVLFETYKDKIYSIALRFSGDQALAMDIAQDTFLKLYSSIADFRGESQFSTWVYRLVV
NSCLDHKRKSWRMIPLADELLAVMRAPGDALHAVIRTEMSERVQRAVEKLPEEQRIVVVLRYTEGLAYEQIAEVIGCSMG
TVASRLNRAHRALERRLANLKGAAHV
>Mature_186_residues
MVLECTDRELVEGCRRGEREAFRVLFETYKDKIYSIALRFSGDQALAMDIAQDTFLKLYSSIADFRGESQFSTWVYRLVV
NSCLDHKRKSWRMIPLADELLAVMRAPGDALHAVIRTEMSERVQRAVEKLPEEQRIVVVLRYTEGLAYEQIAEVIGCSMG
TVASRLNRAHRALERRLANLKGAAHV

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=191, Percent_Identity=32.9842931937173, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21280; Mature: 21280

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLECTDRELVEGCRRGEREAFRVLFETYKDKIYSIALRFSGDQALAMDIAQDTFLKLYS
CEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHH
SIADFRGESQFSTWVYRLVVNSCLDHKRKSWRMIPLADELLAVMRAPGDALHAVIRTEMS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
ERVQRAVEKLPEEQRIVVVLRYTEGLAYEQIAEVIGCSMGTVASRLNRAHRALERRLANL
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
KGAAHV
CCCCCC
>Mature Secondary Structure
MVLECTDRELVEGCRRGEREAFRVLFETYKDKIYSIALRFSGDQALAMDIAQDTFLKLYS
CEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHH
SIADFRGESQFSTWVYRLVVNSCLDHKRKSWRMIPLADELLAVMRAPGDALHAVIRTEMS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
ERVQRAVEKLPEEQRIVVVLRYTEGLAYEQIAEVIGCSMGTVASRLNRAHRALERRLANL
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
KGAAHV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]