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The map label for this gene is macB [H]

Identifier: 116623018

GI number: 116623018

Start: 4956863

End: 4959229

Strand: Reverse

Name: macB [H]

Synonym: Acid_3922

Alternate gene names: 116623018

Gene position: 4959229-4956863 (Counterclockwise)

Preceding gene: 116623019

Following gene: 116623017

Centisome position: 49.76

GC content: 62.57

Gene sequence:

>2367_bases
ATGGACGCTCTCGTTCACGATGTTCGGTACGCCGCCCGAGCTTTTTTGCGGTCCCCCGGATTTGCGGTAGTTGCGGCCGT
TACGCTGGCCCTCGGAATTGGAGCCAACACCGCGATCTTCAGCCTCGTGCATACGGTCCTGCTGAAACCACTGCCGTATC
GCGATCCGTCGCGCCTCATCGTCGCCTGGGACACCTACCTCCCTCAGAACAAAATGCTCCCGATGTTTCCTAAAATCGGG
GTAGCCCCTCCCGAGCTCGAACTGTGGCGGCAACAACACGAGGTCTTCGAAGACACCGCGTGGTATCGCTACGTCCCCTT
CGAAATGGCGTTAAACGCGCCCGGCGCGGAGGCTCTCAGCATTCATGCGGGATTCTGTTCGACGAATTTTCTCCGGGTGC
TCGGCGCCGCGCCCGCCCTCGGCCGGAGCTTCGCCAATGATGAGCCGCCCAATTCAGCGCTGATCAGCGACAAGCTCTGG
CGCACGCACTTCGCCGCGGACCCTGGCGTTGCCGGCAGAGCGATTCGCCTGAATGACGATGTCTTTACCGTGATAGGCGT
TATGCCGCCCGGCTTCAGCTTTCCCGAATGGGCCGACCTGTGGTTGCCGCCCGGGCCGCTCTATGGCGACGAGCTGACCA
ATCCGGTTCGTCACGCCGTCGGATTCATCGGGCGGCTGAAGCCAACCGTCACCACACTACAGGCTTCCACCCGGCTGGGT
ACGCTCTCCGCCCGGCTTGCCGGCGAGCATCCGAGTACCAGCACGGGGTGGGGCATGCGGGTATCGAATCTTCAGGAGGA
TCTTACGGCCAGGATCCGTCCCGCCCTGCTGATGTTGTTGGGCGCAGTCGCATTGGTGCTGCTGATCGCATGCAGTAACG
TTGCCAGCCTCCTTCTGGCGCGCGCCAGCAGCCGGTCGCGGGAGATCGCGATACGGAGCGCGCTCGGCGCGGGAACCTGG
CGGATCGCCCGCCAACTGTTCACCGAAGGCATTCTTCTGTCGGTGGCCGGCGGCGCCGCTGGACTTGGGGTCGGAGAACT
CGGATTGAAACTGCTTTCTCCGGTCCCCACACCACTCGATTGGAATGTGCTCATTTTCCTGATGGCGATTTCGTTCGCTA
CGGGTCTTGCCTGCGGCGCCGCTCCGGTAATTCAGACGCTGCGCAGCGACACCAATGCCGTGATCAAGACGGGATCGGCC
ACCGGTGGCGGCGCCGGCGGGATGCGCTCCGCGCTGGTGGTTGCCGAATTGGCGCTGGCGATGCTGTTGGTTACCGGCGC
GGGAAATCTCGTCAAGAGTTTTGTGCGCCTGTCGCATGTCGATCCCGGATTCAGCTCGCGTGGCCTGCTCACGATGCGCC
TGGCGATTCCGAAATCGCGCAAACCCGAGGTCCTCTTCCGCCGCATTCAGGACGCCGTGAAGCAGATTCCGGGCGTCGAT
TCCTTCGCGTCCACGAATACCTTGCCGTTGGTTCCCAGTCACGGCAATGCCGGCCGCTTCAACGTTCCAGGCAGCCCGCT
AATCAGTTCCGACTCGCTTCCCGCCGCGCAACTCCGCTGGGTCAGCCCGGATTATTTCAGGGTCATGCGCATCCCGATTC
GCTTCGGCAGGGCTTTCGACGAGCGGGATTTGGACCGGCCTGTTGTGATTATCAATGAGACCATGGCCCGCCGCTTTTGG
CCGGGACGGGATCCGGTCGGCCTCAGGTTCATCACCGGACCGTGGGGTCCGAATCCCGCCTGGTCCACAATCATCGGGGT
CGTAGGCGATGTGAAGCAATTCGGTTTGGATTCCGAGCCGAGCCTTGACCTATACTATCCGGCGCTCGATCCACTATCGA
TCACGGTTCACACGGCGGGGAATCCGAAATCGCTGATCGGTCCCGTGCGGGCAGCAATTCAATCGGTAGACCCCGAAATC
CCAGCGTCGGAGGTTCGCACGATGGATCAAGTGCTGGAAGAATCGGCCGCCGCCCAGCGCTGGACCATGTCGTTACTGGG
TGCGTTCGCGGCTCTCGCGATGGCGCTTGCCCTTGTGGGCGTCTACGGGGTCGTTTCCTGGTCGGTAACTCAGCGCACGC
GCGAGATTGGGATTCGCGTGACGCTCGGCGCTTCACCCCGGACAATCGTAGGCGAGGCGCTCGGACACGGAATCAGACTC
ACCGCATTGGGACTGGCTATCGGCCTGATGTGCGCATTTCTGATGCGCCGTTCCCTGCCGAGCCTGGTCTTCGACGTGAG
CCCGTCCGATCCCCTGATCTATCTGGGAGTAGTGGCGCTGATGTTCACCGTCGCGCTGGCGGCATGTTACATCCCGGCTC
GCCGCGCTAGCCGGGTCGATCCTCTGATCGCATTACGCTGGGAATGA

Upstream 100 bases:

>100_bases
AGCCCGGCCACGTCGCCCCGCAAGTGATCGCCGACATCGCGGCGTTCATCAAGCCTTAGCGCGGTACGCGGGTGCGCCCG
GGAAAGTTCTAGACTGAACC

Downstream 100 bases:

>100_bases
CCGATTGTCACTTTCTGCGCCCCTATCTCGTCTGACTGTCGTGAAGAGGCGGCGAGAATCGGAGGAGTCGCGTTGAAAAT
CGGGTCGTGGCACTATTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MDALVHDVRYAARAFLRSPGFAVVAAVTLALGIGANTAIFSLVHTVLLKPLPYRDPSRLIVAWDTYLPQNKMLPMFPKIG
VAPPELELWRQQHEVFEDTAWYRYVPFEMALNAPGAEALSIHAGFCSTNFLRVLGAAPALGRSFANDEPPNSALISDKLW
RTHFAADPGVAGRAIRLNDDVFTVIGVMPPGFSFPEWADLWLPPGPLYGDELTNPVRHAVGFIGRLKPTVTTLQASTRLG
TLSARLAGEHPSTSTGWGMRVSNLQEDLTARIRPALLMLLGAVALVLLIACSNVASLLLARASSRSREIAIRSALGAGTW
RIARQLFTEGILLSVAGGAAGLGVGELGLKLLSPVPTPLDWNVLIFLMAISFATGLACGAAPVIQTLRSDTNAVIKTGSA
TGGGAGGMRSALVVAELALAMLLVTGAGNLVKSFVRLSHVDPGFSSRGLLTMRLAIPKSRKPEVLFRRIQDAVKQIPGVD
SFASTNTLPLVPSHGNAGRFNVPGSPLISSDSLPAAQLRWVSPDYFRVMRIPIRFGRAFDERDLDRPVVIINETMARRFW
PGRDPVGLRFITGPWGPNPAWSTIIGVVGDVKQFGLDSEPSLDLYYPALDPLSITVHTAGNPKSLIGPVRAAIQSVDPEI
PASEVRTMDQVLEESAAAQRWTMSLLGAFAALAMALALVGVYGVVSWSVTQRTREIGIRVTLGASPRTIVGEALGHGIRL
TALGLAIGLMCAFLMRRSLPSLVFDVSPSDPLIYLGVVALMFTVALAACYIPARRASRVDPLIALRWE

Sequences:

>Translated_788_residues
MDALVHDVRYAARAFLRSPGFAVVAAVTLALGIGANTAIFSLVHTVLLKPLPYRDPSRLIVAWDTYLPQNKMLPMFPKIG
VAPPELELWRQQHEVFEDTAWYRYVPFEMALNAPGAEALSIHAGFCSTNFLRVLGAAPALGRSFANDEPPNSALISDKLW
RTHFAADPGVAGRAIRLNDDVFTVIGVMPPGFSFPEWADLWLPPGPLYGDELTNPVRHAVGFIGRLKPTVTTLQASTRLG
TLSARLAGEHPSTSTGWGMRVSNLQEDLTARIRPALLMLLGAVALVLLIACSNVASLLLARASSRSREIAIRSALGAGTW
RIARQLFTEGILLSVAGGAAGLGVGELGLKLLSPVPTPLDWNVLIFLMAISFATGLACGAAPVIQTLRSDTNAVIKTGSA
TGGGAGGMRSALVVAELALAMLLVTGAGNLVKSFVRLSHVDPGFSSRGLLTMRLAIPKSRKPEVLFRRIQDAVKQIPGVD
SFASTNTLPLVPSHGNAGRFNVPGSPLISSDSLPAAQLRWVSPDYFRVMRIPIRFGRAFDERDLDRPVVIINETMARRFW
PGRDPVGLRFITGPWGPNPAWSTIIGVVGDVKQFGLDSEPSLDLYYPALDPLSITVHTAGNPKSLIGPVRAAIQSVDPEI
PASEVRTMDQVLEESAAAQRWTMSLLGAFAALAMALALVGVYGVVSWSVTQRTREIGIRVTLGASPRTIVGEALGHGIRL
TALGLAIGLMCAFLMRRSLPSLVFDVSPSDPLIYLGVVALMFTVALAACYIPARRASRVDPLIALRWE
>Mature_788_residues
MDALVHDVRYAARAFLRSPGFAVVAAVTLALGIGANTAIFSLVHTVLLKPLPYRDPSRLIVAWDTYLPQNKMLPMFPKIG
VAPPELELWRQQHEVFEDTAWYRYVPFEMALNAPGAEALSIHAGFCSTNFLRVLGAAPALGRSFANDEPPNSALISDKLW
RTHFAADPGVAGRAIRLNDDVFTVIGVMPPGFSFPEWADLWLPPGPLYGDELTNPVRHAVGFIGRLKPTVTTLQASTRLG
TLSARLAGEHPSTSTGWGMRVSNLQEDLTARIRPALLMLLGAVALVLLIACSNVASLLLARASSRSREIAIRSALGAGTW
RIARQLFTEGILLSVAGGAAGLGVGELGLKLLSPVPTPLDWNVLIFLMAISFATGLACGAAPVIQTLRSDTNAVIKTGSA
TGGGAGGMRSALVVAELALAMLLVTGAGNLVKSFVRLSHVDPGFSSRGLLTMRLAIPKSRKPEVLFRRIQDAVKQIPGVD
SFASTNTLPLVPSHGNAGRFNVPGSPLISSDSLPAAQLRWVSPDYFRVMRIPIRFGRAFDERDLDRPVVIINETMARRFW
PGRDPVGLRFITGPWGPNPAWSTIIGVVGDVKQFGLDSEPSLDLYYPALDPLSITVHTAGNPKSLIGPVRAAIQSVDPEI
PASEVRTMDQVLEESAAAQRWTMSLLGAFAALAMALALVGVYGVVSWSVTQRTREIGIRVTLGASPRTIVGEALGHGIRL
TALGLAIGLMCAFLMRRSLPSLVFDVSPSDPLIYLGVVALMFTVALAACYIPARRASRVDPLIALRWE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=296, Percent_Identity=27.3648648648649, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 84461; Mature: 84461

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALVHDVRYAARAFLRSPGFAVVAAVTLALGIGANTAIFSLVHTVLLKPLPYRDPSRLI
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEE
VAWDTYLPQNKMLPMFPKIGVAPPELELWRQQHEVFEDTAWYRYVPFEMALNAPGAEALS
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHEEECCCCCCEEE
IHAGFCSTNFLRVLGAAPALGRSFANDEPPNSALISDKLWRTHFAADPGVAGRAIRLNDD
EECCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCC
VFTVIGVMPPGFSFPEWADLWLPPGPLYGDELTNPVRHAVGFIGRLKPTVTTLQASTRLG
EEEEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLSARLAGEHPSTSTGWGMRVSNLQEDLTARIRPALLMLLGAVALVLLIACSNVASLLLA
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RASSRSREIAIRSALGAGTWRIARQLFTEGILLSVAGGAAGLGVGELGLKLLSPVPTPLD
HHCCCCHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCC
WNVLIFLMAISFATGLACGAAPVIQTLRSDTNAVIKTGSATGGGAGGMRSALVVAELALA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
MLLVTGAGNLVKSFVRLSHVDPGFSSRGLLTMRLAIPKSRKPEVLFRRIQDAVKQIPGVD
HHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
SFASTNTLPLVPSHGNAGRFNVPGSPLISSDSLPAAQLRWVSPDYFRVMRIPIRFGRAFD
CCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCCHHHEEECCCHHHHHEEHHHHHCCCCC
ERDLDRPVVIINETMARRFWPGRDPVGLRFITGPWGPNPAWSTIIGVVGDVKQFGLDSEP
CCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
SLDLYYPALDPLSITVHTAGNPKSLIGPVRAAIQSVDPEIPASEVRTMDQVLEESAAAQR
CCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WTMSLLGAFAALAMALALVGVYGVVSWSVTQRTREIGIRVTLGASPRTIVGEALGHGIRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCHH
TALGLAIGLMCAFLMRRSLPSLVFDVSPSDPLIYLGVVALMFTVALAACYIPARRASRVD
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLIALRWE
CEEEEECC
>Mature Secondary Structure
MDALVHDVRYAARAFLRSPGFAVVAAVTLALGIGANTAIFSLVHTVLLKPLPYRDPSRLI
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEE
VAWDTYLPQNKMLPMFPKIGVAPPELELWRQQHEVFEDTAWYRYVPFEMALNAPGAEALS
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHEEECCCCCCEEE
IHAGFCSTNFLRVLGAAPALGRSFANDEPPNSALISDKLWRTHFAADPGVAGRAIRLNDD
EECCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCC
VFTVIGVMPPGFSFPEWADLWLPPGPLYGDELTNPVRHAVGFIGRLKPTVTTLQASTRLG
EEEEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLSARLAGEHPSTSTGWGMRVSNLQEDLTARIRPALLMLLGAVALVLLIACSNVASLLLA
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RASSRSREIAIRSALGAGTWRIARQLFTEGILLSVAGGAAGLGVGELGLKLLSPVPTPLD
HHCCCCHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCC
WNVLIFLMAISFATGLACGAAPVIQTLRSDTNAVIKTGSATGGGAGGMRSALVVAELALA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
MLLVTGAGNLVKSFVRLSHVDPGFSSRGLLTMRLAIPKSRKPEVLFRRIQDAVKQIPGVD
HHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
SFASTNTLPLVPSHGNAGRFNVPGSPLISSDSLPAAQLRWVSPDYFRVMRIPIRFGRAFD
CCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCCHHHEEECCCHHHHHEEHHHHHCCCCC
ERDLDRPVVIINETMARRFWPGRDPVGLRFITGPWGPNPAWSTIIGVVGDVKQFGLDSEP
CCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
SLDLYYPALDPLSITVHTAGNPKSLIGPVRAAIQSVDPEIPASEVRTMDQVLEESAAAQR
CCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WTMSLLGAFAALAMALALVGVYGVVSWSVTQRTREIGIRVTLGASPRTIVGEALGHGIRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCHH
TALGLAIGLMCAFLMRRSLPSLVFDVSPSDPLIYLGVVALMFTVALAACYIPARRASRVD
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLIALRWE
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA