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The map label for this gene is iolG [H]

Identifier: 116622998

GI number: 116622998

Start: 4933780

End: 4935216

Strand: Direct

Name: iolG [H]

Synonym: Acid_3902

Alternate gene names: 116622998

Gene position: 4933780-4935216 (Clockwise)

Preceding gene: 116622997

Following gene: 116623003

Centisome position: 49.51

GC content: 63.95

Gene sequence:

>1437_bases
GTGTCAGATTCCACAACCCGCAGATTCTTTCTTGGGGCCGTTACGGCCGCCGCCGCCACCCGCGTCTGGGGCGCAAATGA
CAAAATCAATATCGCAATCGTAGGACTCGGTGGTCGCGGCACCAACCACCTGAGTCAATATACCCGTTTGACCGAGTCGC
GCGTCGCCGTGTTATGCGACGTGAATCAGGCTGCACGTGAAAAGGCGCAGGCCACGCTCGCCCGCGGCAACTTCGAGAAG
GCCAAAGAGTATGAAGACATGCGCCAGGCCTTCGCCGATCCCGGTGTCGATGCCGTTTCCATCGCCACTCCCAATCACTG
GCACGCGCTCGCCGCCATCTGGGCGATGAAGGCCGGCAAGGATGTATATGGCGAAAAGCCCGCCTGCTACAACATCTATG
AAGGCCAGAAGATGATCGCCGTGCAGCAGCAGACCAAGCGCATCATGCAGGTCGGCTCTCAGCATCGCAGCACGCCGTTC
AAGATGAAGGCCATCGCTGCCCTGCAGCAAGGACTCATCGGCAAGATCTACATGGCCAAGGGACTCTGCTATAAGCGCCG
CCCCTCCATCGGCCACACCCCTGACGCTCCCACGCCTCCCGGCCTGAACTGGGACCTCTTCCTCGGCCCCGCGCCCATGC
GGCCCTACAACCCTAAGCGTTTCGCATATTACTGGCACTGGTTCTGGGACACTGGCAACGGCGACATCGGCAACCAGGGC
GTGCACGAAATGGGCATCGCCCGCTGGGGTCTGGGCGATCCCGATTTCCCCAAGACCGCGGTTTCCTTCGGCGGCAAACT
CGGTATTGACGATGACACCGAGACGCCCAACATGCTGACCGCCGGCTTCAACTACGGCGATCGCCAGCTCGTCTTCGAAG
TCCGCGGCAACCTCACCAACGGCGAAGGCACCCGCCAGGGTCGCGTCGTCACCGCCGGCCCCGGAGCCGCCGCGGGTGGA
GGCGCAGGCCGCGCCGGACGTGGACAGCAGCCCGGCGCCGAACCGCCCGCCGCTCCTCCCGCTGCCGCTGCGCCCACCCA
GGTCGGCCCCGCGAGCAATCCCTTGAACGTCGCCGTCGGCGATCTCTTCTACGGCACCGAAGGTTGGGCCGCCATGAGCG
ACCAGGGCTTCCAGGCATATAAGGGTGAGAGCAGCGAGCTCATCATGGAAGAGCGCCCCGAGCGCGGACAGCCCGGCGGC
GATGCCACCGGCCTCCACATGCAGAACTTCCTGCAGGCCTGCAAATCGCGCAATGAGAAGGAACTCCACGATCCCCTCTC
TAACGCTGTTCTCAGCGCCGACCTCTGCCACCTCGCCAACATCAGCTACCGCGTCGGCCGCAAACTGACGCTCGAAGCCG
GCCCCAAATTCACCGGCGACGCCGAAGCCACCAAGATGCTCACCCGCCCCGTATACCGCAAACCCTACGAGGTCTGA

Upstream 100 bases:

>100_bases
CTGCTTACCCGGCCTCGCCAGACCATAACTCTCGGTCCGGATCTTAAAGTATTGTAAATGCCGCGGCCTGTTATAATCAC
ACGCGAAGAGGAGCTTCGCA

Downstream 100 bases:

>100_bases
TCAAGGCAACAAACGCGGATAAGACAAACCTGTGTTTTCTTATCCGCGTTGATCCATGTTCATCCGCGGCCCATTCTGTT
TCTTCGCAAAACGCACGCTC

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSDSTTRRFFLGAVTAAAATRVWGANDKINIAIVGLGGRGTNHLSQYTRLTESRVAVLCDVNQAAREKAQATLARGNFEK
AKEYEDMRQAFADPGVDAVSIATPNHWHALAAIWAMKAGKDVYGEKPACYNIYEGQKMIAVQQQTKRIMQVGSQHRSTPF
KMKAIAALQQGLIGKIYMAKGLCYKRRPSIGHTPDAPTPPGLNWDLFLGPAPMRPYNPKRFAYYWHWFWDTGNGDIGNQG
VHEMGIARWGLGDPDFPKTAVSFGGKLGIDDDTETPNMLTAGFNYGDRQLVFEVRGNLTNGEGTRQGRVVTAGPGAAAGG
GAGRAGRGQQPGAEPPAAPPAAAAPTQVGPASNPLNVAVGDLFYGTEGWAAMSDQGFQAYKGESSELIMEERPERGQPGG
DATGLHMQNFLQACKSRNEKELHDPLSNAVLSADLCHLANISYRVGRKLTLEAGPKFTGDAEATKMLTRPVYRKPYEV

Sequences:

>Translated_478_residues
MSDSTTRRFFLGAVTAAAATRVWGANDKINIAIVGLGGRGTNHLSQYTRLTESRVAVLCDVNQAAREKAQATLARGNFEK
AKEYEDMRQAFADPGVDAVSIATPNHWHALAAIWAMKAGKDVYGEKPACYNIYEGQKMIAVQQQTKRIMQVGSQHRSTPF
KMKAIAALQQGLIGKIYMAKGLCYKRRPSIGHTPDAPTPPGLNWDLFLGPAPMRPYNPKRFAYYWHWFWDTGNGDIGNQG
VHEMGIARWGLGDPDFPKTAVSFGGKLGIDDDTETPNMLTAGFNYGDRQLVFEVRGNLTNGEGTRQGRVVTAGPGAAAGG
GAGRAGRGQQPGAEPPAAPPAAAAPTQVGPASNPLNVAVGDLFYGTEGWAAMSDQGFQAYKGESSELIMEERPERGQPGG
DATGLHMQNFLQACKSRNEKELHDPLSNAVLSADLCHLANISYRVGRKLTLEAGPKFTGDAEATKMLTRPVYRKPYEV
>Mature_477_residues
SDSTTRRFFLGAVTAAAATRVWGANDKINIAIVGLGGRGTNHLSQYTRLTESRVAVLCDVNQAAREKAQATLARGNFEKA
KEYEDMRQAFADPGVDAVSIATPNHWHALAAIWAMKAGKDVYGEKPACYNIYEGQKMIAVQQQTKRIMQVGSQHRSTPFK
MKAIAALQQGLIGKIYMAKGLCYKRRPSIGHTPDAPTPPGLNWDLFLGPAPMRPYNPKRFAYYWHWFWDTGNGDIGNQGV
HEMGIARWGLGDPDFPKTAVSFGGKLGIDDDTETPNMLTAGFNYGDRQLVFEVRGNLTNGEGTRQGRVVTAGPGAAAGGG
AGRAGRGQQPGAEPPAAPPAAAAPTQVGPASNPLNVAVGDLFYGTEGWAAMSDQGFQAYKGESSELIMEERPERGQPGGD
ATGLHMQNFLQACKSRNEKELHDPLSNAVLSADLCHLANISYRVGRKLTLEAGPKFTGDAEATKMLTRPVYRKPYEV

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 51613; Mature: 51482

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSTTRRFFLGAVTAAAATRVWGANDKINIAIVGLGGRGTNHLSQYTRLTESRVAVLCD
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEC
VNQAAREKAQATLARGNFEKAKEYEDMRQAFADPGVDAVSIATPNHWHALAAIWAMKAGK
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCC
DVYGEKPACYNIYEGQKMIAVQQQTKRIMQVGSQHRSTPFKMKAIAALQQGLIGKIYMAK
HHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHC
GLCYKRRPSIGHTPDAPTPPGLNWDLFLGPAPMRPYNPKRFAYYWHWFWDTGNGDIGNQG
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCC
VHEMGIARWGLGDPDFPKTAVSFGGKLGIDDDTETPNMLTAGFNYGDRQLVFEVRGNLTN
HHHHHHHHCCCCCCCCCHHHHHCCCEECCCCCCCCCCEEEECCCCCCEEEEEEEECCCCC
GEGTRQGRVVTAGPGAAAGGGAGRAGRGQQPGAEPPAAPPAAAAPTQVGPASNPLNVAVG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
DLFYGTEGWAAMSDQGFQAYKGESSELIMEERPERGQPGGDATGLHMQNFLQACKSRNEK
EEEECCCCCEECCCCCCHHHCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHH
ELHDPLSNAVLSADLCHLANISYRVGRKLTLEAGPKFTGDAEATKMLTRPVYRKPYEV
HHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDSTTRRFFLGAVTAAAATRVWGANDKINIAIVGLGGRGTNHLSQYTRLTESRVAVLCD
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEC
VNQAAREKAQATLARGNFEKAKEYEDMRQAFADPGVDAVSIATPNHWHALAAIWAMKAGK
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCC
DVYGEKPACYNIYEGQKMIAVQQQTKRIMQVGSQHRSTPFKMKAIAALQQGLIGKIYMAK
HHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHC
GLCYKRRPSIGHTPDAPTPPGLNWDLFLGPAPMRPYNPKRFAYYWHWFWDTGNGDIGNQG
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCC
VHEMGIARWGLGDPDFPKTAVSFGGKLGIDDDTETPNMLTAGFNYGDRQLVFEVRGNLTN
HHHHHHHHCCCCCCCCCHHHHHCCCEECCCCCCCCCCEEEECCCCCCEEEEEEEECCCCC
GEGTRQGRVVTAGPGAAAGGGAGRAGRGQQPGAEPPAAPPAAAAPTQVGPASNPLNVAVG
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
DLFYGTEGWAAMSDQGFQAYKGESSELIMEERPERGQPGGDATGLHMQNFLQACKSRNEK
EEEECCCCCEECCCCCCHHHCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHH
ELHDPLSNAVLSADLCHLANISYRVGRKLTLEAGPKFTGDAEATKMLTRPVYRKPYEV
HHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA