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The map label for this gene is yhdN [H]

Identifier: 116622960

GI number: 116622960

Start: 4896880

End: 4897911

Strand: Direct

Name: yhdN [H]

Synonym: Acid_3862

Alternate gene names: 116622960

Gene position: 4896880-4897911 (Clockwise)

Preceding gene: 116622958

Following gene: 116622962

Centisome position: 49.14

GC content: 60.56

Gene sequence:

>1032_bases
ATGCCGGATTCGACAATCGGAAGGCGAACTGTTCTCGGAGGAATTGCCGGGCTGACGGCTTCCGGTTTCGCTCAAACCAA
CGCTCCTTCCGGCATGCCCTTGCGGCCGCTCGGCAGCACGGGCGAAAAGGTCTCGTGCATCGGCCTTGGCGGCTCCCACA
TCGGCGCGCCGAAGGTGAGCGATGACGAGGCGATCCGGATTATGCGCTCGGCGATCGATCGCGGGCTCACGTTCATGGAC
AATTCGTGGGACTACAACGGCGGCGTCAGCGAAGAGCGGATGGGGAAGGCGTTGCGCGACGGCTACCGGCAGAAGGTTTT
CCTGATGACCAAGATCGACGGGCGCACGAGACAGGAGGCCGCGAAGCAGATCGAGGAATCGCTGCGAAGGCTGCAGACCG
ATCACCTGGACCTGGTTCAGCATCACGAGATCATCCGCTTCGACGATCCTGACCGGATTTTCGCGGCCGGCGGCGCGCAG
GAGGCGGTGTTGGCCGCGAAGCAGGCTGGGAAGGTGCGGTTCATCGGGTTCACGGGCCACAAAGATCCCCACATACACCT
TTATATGCTGAGCGTCTGCGCGGCGCACGGCTTCCATCCGGATACGGTGCAGATGCCGCTCAATGTGATGGACGCGCATT
TCCGCAGCTTCGAAAAGCTGGTACTGCCGGAACTGGTGAAGCAGAAGATCGGCGTACTCGGGATGAAGAGCATGGGGAGC
AGCGTAATTTTGAAGAGCAAGGTGGTCACGCCGTTGGAATGCCTGCACTACGCGCTCAACCTGCCGACCTCGGTGGTAAT
TACGGGAATCGACAGCCCGCAGATTCTGGATCAGGCGTTCGAAGCAGCGCACACCTTCCAACCGATGTCGAAGCAGCAGA
TTGCCGGGCTGCTGAGCAAGACTAAGCCGGCGGCGGAACAGGGTCAGTACGAATTGTTCAAGACCAGCTCGCACTTCGAT
TCCACGGCCAAGCATCCGGAATGGCTCGGCGAGGAATCGGCGCGCGTCAAGGAGTTAACGCAAGGGCAATAA

Upstream 100 bases:

>100_bases
GGTGCGCACGCAGGCGCACCGCGGTGCGTGACACTGGCTACGAAGCGCATCTATCATTAGCGAGGCGCGGGTCCTAGAAT
GGCGGTAGGTGCGCAAGGAG

Downstream 100 bases:

>100_bases
CATTAATCCGGAGGAAGTTCGGAAGGCACTTTTCCGTGCACCGCGATATCGGTGACCATTCGCAAGGCGCGCGTATATGC
TTGCAGCGCGAGGCGCTCGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPDSTIGRRTVLGGIAGLTASGFAQTNAPSGMPLRPLGSTGEKVSCIGLGGSHIGAPKVSDDEAIRIMRSAIDRGLTFMD
NSWDYNGGVSEERMGKALRDGYRQKVFLMTKIDGRTRQEAAKQIEESLRRLQTDHLDLVQHHEIIRFDDPDRIFAAGGAQ
EAVLAAKQAGKVRFIGFTGHKDPHIHLYMLSVCAAHGFHPDTVQMPLNVMDAHFRSFEKLVLPELVKQKIGVLGMKSMGS
SVILKSKVVTPLECLHYALNLPTSVVITGIDSPQILDQAFEAAHTFQPMSKQQIAGLLSKTKPAAEQGQYELFKTSSHFD
STAKHPEWLGEESARVKELTQGQ

Sequences:

>Translated_343_residues
MPDSTIGRRTVLGGIAGLTASGFAQTNAPSGMPLRPLGSTGEKVSCIGLGGSHIGAPKVSDDEAIRIMRSAIDRGLTFMD
NSWDYNGGVSEERMGKALRDGYRQKVFLMTKIDGRTRQEAAKQIEESLRRLQTDHLDLVQHHEIIRFDDPDRIFAAGGAQ
EAVLAAKQAGKVRFIGFTGHKDPHIHLYMLSVCAAHGFHPDTVQMPLNVMDAHFRSFEKLVLPELVKQKIGVLGMKSMGS
SVILKSKVVTPLECLHYALNLPTSVVITGIDSPQILDQAFEAAHTFQPMSKQQIAGLLSKTKPAAEQGQYELFKTSSHFD
STAKHPEWLGEESARVKELTQGQ
>Mature_342_residues
PDSTIGRRTVLGGIAGLTASGFAQTNAPSGMPLRPLGSTGEKVSCIGLGGSHIGAPKVSDDEAIRIMRSAIDRGLTFMDN
SWDYNGGVSEERMGKALRDGYRQKVFLMTKIDGRTRQEAAKQIEESLRRLQTDHLDLVQHHEIIRFDDPDRIFAAGGAQE
AVLAAKQAGKVRFIGFTGHKDPHIHLYMLSVCAAHGFHPDTVQMPLNVMDAHFRSFEKLVLPELVKQKIGVLGMKSMGSS
VILKSKVVTPLECLHYALNLPTSVVITGIDSPQILDQAFEAAHTFQPMSKQQIAGLLSKTKPAAEQGQYELFKTSSHFDS
TAKHPEWLGEESARVKELTQGQ

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081735, Length=161, Percent_Identity=34.1614906832298, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24646159, Length=213, Percent_Identity=30.5164319248826, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646155, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37511; Mature: 37380

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSTIGRRTVLGGIAGLTASGFAQTNAPSGMPLRPLGSTGEKVSCIGLGGSHIGAPKVS
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
DDEAIRIMRSAIDRGLTFMDNSWDYNGGVSEERMGKALRDGYRQKVFLMTKIDGRTRQEA
CHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHCHHCEEEEEEECCCCHHHHH
AKQIEESLRRLQTDHLDLVQHHEIIRFDDPDRIFAAGGAQEAVLAAKQAGKVRFIGFTGH
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHHHHHHCCCEEEEEECCC
KDPHIHLYMLSVCAAHGFHPDTVQMPLNVMDAHFRSFEKLVLPELVKQKIGVLGMKSMGS
CCCCEEEHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVILKSKVVTPLECLHYALNLPTSVVITGIDSPQILDQAFEAAHTFQPMSKQQIAGLLSK
CEEEHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TKPAAEQGQYELFKTSSHFDSTAKHPEWLGEESARVKELTQGQ
CCCCHHCCCEEEEECCCCCCCCCCCCHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
PDSTIGRRTVLGGIAGLTASGFAQTNAPSGMPLRPLGSTGEKVSCIGLGGSHIGAPKVS
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
DDEAIRIMRSAIDRGLTFMDNSWDYNGGVSEERMGKALRDGYRQKVFLMTKIDGRTRQEA
CHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHCHHCEEEEEEECCCCHHHHH
AKQIEESLRRLQTDHLDLVQHHEIIRFDDPDRIFAAGGAQEAVLAAKQAGKVRFIGFTGH
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHHHHHHCCCEEEEEECCC
KDPHIHLYMLSVCAAHGFHPDTVQMPLNVMDAHFRSFEKLVLPELVKQKIGVLGMKSMGS
CCCCEEEHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVILKSKVVTPLECLHYALNLPTSVVITGIDSPQILDQAFEAAHTFQPMSKQQIAGLLSK
CEEEHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TKPAAEQGQYELFKTSSHFDSTAKHPEWLGEESARVKELTQGQ
CCCCHHCCCEEEEECCCCCCCCCCCCHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]