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The map label for this gene is ptrB [H]

Identifier: 116622809

GI number: 116622809

Start: 4707748

End: 4709859

Strand: Direct

Name: ptrB [H]

Synonym: Acid_3709

Alternate gene names: 116622809

Gene position: 4707748-4709859 (Clockwise)

Preceding gene: 116622804

Following gene: 116622814

Centisome position: 47.24

GC content: 60.23

Gene sequence:

>2112_bases
ATGAAGCCGTTCCGGAAATCTATTGTTCTCGGCCTTCTGACTACCGCACTCATGACTTCTCAAACACCGAAATCCCCGGC
ACCGCCGGTTGCCCCGCAGCTCGATCATCGCGAAGTCCGCCATGGCGCCACGGTCGTTGACCCGTATTTCTGGCTACGCG
AGAAGGCCAACCCCAAAGTGGTCGAGTACCTGGAATCCGAAAATGCGTACACCGAGGCGATGACGAAGGAGATCAAGCCC
TTCAGCGACGCCCTCTACAAGGAGATGCTCGGGCGCATCAAGCAGACCGACCTCTCCGTCCCCGCGCGCCGCGGTCCCTA
CCTCTACTACTCGCGCACCGAGGAGGGCAAGCAGTACCCCATACAATGCCGGCGCAAGGGCAGCATGGACGCGCCCGAAG
AAGTGCTGCTCGATCTCAACGAGCTCGGCAAGGACAAGAAGTTCGTCTCGCTCGGCAGCTTCACGATCAGCGACGATCAC
AACCTGCTCGCCTATACGATCGATTACGTCGGCTTCCGCCAATACGCGCTCCACGTGAAGGACCTGCGCACGGGCGCCAC
TCTCCCCGACACTACCGAGCGCGTCACCACCGTGGCTTGGGCCGCCGACAACAGGACGCTTTTCCTCACTACCGAGGACG
ACGTCACCAAGCGGAGCGACAAGCTTTTCCGCCACGTGCTCGGCGCCTCCGCCTTCGACCTGCTCTACGAAGACAAGGAT
GAGCTCTACGACGTCACGCTCGGCAAGACGCGCGACCACCAGTACCTCATCCTGCTCAGCGAATCCAAAGACACCAGCGA
GAACCTCTACCTGCGCGCGTCCGATCCTCAAGGCAGCTTCGCCGTCTTCCTGCCGCGCGAAAACAAGCACCGTTATTACC
TGGATCATCGCGACGGCGTCTTCTACATTCGCACCAACAAAACGGGCAAGGATTTCGCGGTCATGACCGCATCCGCGAAG
GATATCGCGCCCAAGAACTGGAAGCCCTTCATCGCCCACCAGGAGGGTGTCCGCATCGAAGAGATCGATCTCTTCAAGGA
ATTCGCAGTCTCGGTCGAGAAGACGCAGGCCCTCAACCGGGTGCGCGTCTACAACTTTAAGACCGGCGCGTGGACCACCG
TCGCTTTCCCCGAGCCCGTATACTCCGTCTTTCCGGGCGGAACGCTGGATTTCGATTCCATCACCTACCGGTACAGCTAC
CAGAGCCTGATCACCCCGCCCAGTGTCTTCGACTACGATACGCATACCGGAAAATCGGCCCTGCTCAAGCAGCAGGAAGT
CCTCGGCGGCTACGACCCGAAGCAGTATGCGAGCGAGCGACTGTGGGCCACCGCGCGCGATGGCGTCAAGGTCCCGATCT
CCATCGTCTACAAGAAAGGACTCGTGCGCGACGGCAAGTCGCCGCTCTTCCTCTATGCATACGGTTCGTATGGCTTCGGC
ACGCCGCCTAACTTCTCGAGCAATCGGCTGAGCCTGCTCGATCGCGGCATGACCTACGCCATCGCCCACATCCGCGGCGG
CGACGAAATGGGCGAGCAGTGGCGCGAAGACGGCATGCTCATGAAGAAGAAGAATACCTTCTTCGATTTCATCGATTGCG
CCGAGTATCTCATCAAAGAGAAGTGGACATCCGCCGCGGGTCTCGTGATCGAAGGCGGCAGCGCCGGTGGCCTCCTCATG
GGCGCCGTTGTCAACCTGCGTCCCGATCTCTTCCGCGCCGTCCACGCGGCCGTCCCGTTCGTGGACGTGATGAACACGAT
GATGGACGCGACCCTGCCGTTAACCGTCGGCGAGTACCTGGAGTGGGGCAACCCCAACGAGAAACCGGCGTACGATTACA
TGAAGACGTACAGCCCTTACGACAACCTCGAGAAGCGCGGTTACCCGGCCATACTGGTGACTACGAGCTTCCACGATAGT
CAGGTCATGTACTGGGAGCCCGCCAAGTACGTCGCCCGCCTGCGCACGGTGAAGACGGATTCCAATCCGCTACTCCTCAA
AATCAAGATGGATCCAGCCGGCCACGGCGGCGCCTCCGGCCGCTACGACAAACTCAAAGACACTGCCTTCGAATACGCCT
GGATGCTGAGTCAGGTAGGTAGAGCCAAATAG

Upstream 100 bases:

>100_bases
TTCACCAGACAAATACGCGCTGCCCGCTTTGCCGAAGGCAGTTTTTCCAAACTATCTGTCCGCTTGCCCCAACGTGCTTC
CACGGAGTAGCCTGAATGCC

Downstream 100 bases:

>100_bases
CCGGTCGATTTCTACGCGCCCCCGAGCTCGCGCCACAGCGCCCGGTAATACTTGAGAAACCGCTCCGGCTCCTTACTCTC
GTTGGCCTCGCAGAGAGTCC

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MKPFRKSIVLGLLTTALMTSQTPKSPAPPVAPQLDHREVRHGATVVDPYFWLREKANPKVVEYLESENAYTEAMTKEIKP
FSDALYKEMLGRIKQTDLSVPARRGPYLYYSRTEEGKQYPIQCRRKGSMDAPEEVLLDLNELGKDKKFVSLGSFTISDDH
NLLAYTIDYVGFRQYALHVKDLRTGATLPDTTERVTTVAWAADNRTLFLTTEDDVTKRSDKLFRHVLGASAFDLLYEDKD
ELYDVTLGKTRDHQYLILLSESKDTSENLYLRASDPQGSFAVFLPRENKHRYYLDHRDGVFYIRTNKTGKDFAVMTASAK
DIAPKNWKPFIAHQEGVRIEEIDLFKEFAVSVEKTQALNRVRVYNFKTGAWTTVAFPEPVYSVFPGGTLDFDSITYRYSY
QSLITPPSVFDYDTHTGKSALLKQQEVLGGYDPKQYASERLWATARDGVKVPISIVYKKGLVRDGKSPLFLYAYGSYGFG
TPPNFSSNRLSLLDRGMTYAIAHIRGGDEMGEQWREDGMLMKKKNTFFDFIDCAEYLIKEKWTSAAGLVIEGGSAGGLLM
GAVVNLRPDLFRAVHAAVPFVDVMNTMMDATLPLTVGEYLEWGNPNEKPAYDYMKTYSPYDNLEKRGYPAILVTTSFHDS
QVMYWEPAKYVARLRTVKTDSNPLLLKIKMDPAGHGGASGRYDKLKDTAFEYAWMLSQVGRAK

Sequences:

>Translated_703_residues
MKPFRKSIVLGLLTTALMTSQTPKSPAPPVAPQLDHREVRHGATVVDPYFWLREKANPKVVEYLESENAYTEAMTKEIKP
FSDALYKEMLGRIKQTDLSVPARRGPYLYYSRTEEGKQYPIQCRRKGSMDAPEEVLLDLNELGKDKKFVSLGSFTISDDH
NLLAYTIDYVGFRQYALHVKDLRTGATLPDTTERVTTVAWAADNRTLFLTTEDDVTKRSDKLFRHVLGASAFDLLYEDKD
ELYDVTLGKTRDHQYLILLSESKDTSENLYLRASDPQGSFAVFLPRENKHRYYLDHRDGVFYIRTNKTGKDFAVMTASAK
DIAPKNWKPFIAHQEGVRIEEIDLFKEFAVSVEKTQALNRVRVYNFKTGAWTTVAFPEPVYSVFPGGTLDFDSITYRYSY
QSLITPPSVFDYDTHTGKSALLKQQEVLGGYDPKQYASERLWATARDGVKVPISIVYKKGLVRDGKSPLFLYAYGSYGFG
TPPNFSSNRLSLLDRGMTYAIAHIRGGDEMGEQWREDGMLMKKKNTFFDFIDCAEYLIKEKWTSAAGLVIEGGSAGGLLM
GAVVNLRPDLFRAVHAAVPFVDVMNTMMDATLPLTVGEYLEWGNPNEKPAYDYMKTYSPYDNLEKRGYPAILVTTSFHDS
QVMYWEPAKYVARLRTVKTDSNPLLLKIKMDPAGHGGASGRYDKLKDTAFEYAWMLSQVGRAK
>Mature_703_residues
MKPFRKSIVLGLLTTALMTSQTPKSPAPPVAPQLDHREVRHGATVVDPYFWLREKANPKVVEYLESENAYTEAMTKEIKP
FSDALYKEMLGRIKQTDLSVPARRGPYLYYSRTEEGKQYPIQCRRKGSMDAPEEVLLDLNELGKDKKFVSLGSFTISDDH
NLLAYTIDYVGFRQYALHVKDLRTGATLPDTTERVTTVAWAADNRTLFLTTEDDVTKRSDKLFRHVLGASAFDLLYEDKD
ELYDVTLGKTRDHQYLILLSESKDTSENLYLRASDPQGSFAVFLPRENKHRYYLDHRDGVFYIRTNKTGKDFAVMTASAK
DIAPKNWKPFIAHQEGVRIEEIDLFKEFAVSVEKTQALNRVRVYNFKTGAWTTVAFPEPVYSVFPGGTLDFDSITYRYSY
QSLITPPSVFDYDTHTGKSALLKQQEVLGGYDPKQYASERLWATARDGVKVPISIVYKKGLVRDGKSPLFLYAYGSYGFG
TPPNFSSNRLSLLDRGMTYAIAHIRGGDEMGEQWREDGMLMKKKNTFFDFIDCAEYLIKEKWTSAAGLVIEGGSAGGLLM
GAVVNLRPDLFRAVHAAVPFVDVMNTMMDATLPLTVGEYLEWGNPNEKPAYDYMKTYSPYDNLEKRGYPAILVTTSFHDS
QVMYWEPAKYVARLRTVKTDSNPLLLKIKMDPAGHGGASGRYDKLKDTAFEYAWMLSQVGRAK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=677, Percent_Identity=28.5081240768095, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI284172420, Length=567, Percent_Identity=29.9823633156966, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI284172413, Length=567, Percent_Identity=29.9823633156966, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI70778815, Length=567, Percent_Identity=29.9823633156966, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI284172438, Length=567, Percent_Identity=29.9823633156966, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI284172431, Length=567, Percent_Identity=29.9823633156966, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI108860686, Length=275, Percent_Identity=37.0909090909091, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI108860692, Length=213, Percent_Identity=38.9671361502347, Blast_Score=145, Evalue=1e-34,
Organism=Escherichia coli, GI1788150, Length=676, Percent_Identity=40.9763313609467, Blast_Score=520, Evalue=1e-148,
Organism=Drosophila melanogaster, GI24583414, Length=715, Percent_Identity=27.2727272727273, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI221510989, Length=691, Percent_Identity=24.8914616497829, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 79740; Mature: 79740

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFRKSIVLGLLTTALMTSQTPKSPAPPVAPQLDHREVRHGATVVDPYFWLREKANPKV
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEECHHHHHHCCCCCHH
VEYLESENAYTEAMTKEIKPFSDALYKEMLGRIKQTDLSVPARRGPYLYYSRTEEGKQYP
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCC
IQCRRKGSMDAPEEVLLDLNELGKDKKFVSLGSFTISDDHNLLAYTIDYVGFRQYALHVK
HHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCEEECCCCCEEEEEEEHHHHHHHHEEHH
DLRTGATLPDTTERVTTVAWAADNRTLFLTTEDDVTKRSDKLFRHVLGASAFDLLYEDKD
HHCCCCCCCCCCHHEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHCCCH
ELYDVTLGKTRDHQYLILLSESKDTSENLYLRASDPQGSFAVFLPRENKHRYYLDHRDGV
HEEEEECCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCCEEEEECCCCE
FYIRTNKTGKDFAVMTASAKDIAPKNWKPFIAHQEGVRIEEIDLFKEFAVSVEKTQALNR
EEEEECCCCCCEEEEEECCCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHCE
VRVYNFKTGAWTTVAFPEPVYSVFPGGTLDFDSITYRYSYQSLITPPSVFDYDTHTGKSA
EEEEEECCCCEEEEECCCCHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCHHH
LLKQQEVLGGYDPKQYASERLWATARDGVKVPISIVYKKGLVRDGKSPLFLYAYGSYGFG
HHHHHHHHCCCCHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCC
TPPNFSSNRLSLLDRGMTYAIAHIRGGDEMGEQWREDGMLMKKKNTFFDFIDCAEYLIKE
CCCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHH
KWTSAAGLVIEGGSAGGLLMGAVVNLRPDLFRAVHAAVPFVDVMNTMMDATLPLTVGEYL
HCCCCCCEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
EWGNPNEKPAYDYMKTYSPYDNLEKRGYPAILVTTSFHDSQVMYWEPAKYVARLRTVKTD
HCCCCCCCCHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHEECC
SNPLLLKIKMDPAGHGGASGRYDKLKDTAFEYAWMLSQVGRAK
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKPFRKSIVLGLLTTALMTSQTPKSPAPPVAPQLDHREVRHGATVVDPYFWLREKANPKV
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEECHHHHHHCCCCCHH
VEYLESENAYTEAMTKEIKPFSDALYKEMLGRIKQTDLSVPARRGPYLYYSRTEEGKQYP
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCC
IQCRRKGSMDAPEEVLLDLNELGKDKKFVSLGSFTISDDHNLLAYTIDYVGFRQYALHVK
HHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCEEECCCCCEEEEEEEHHHHHHHHEEHH
DLRTGATLPDTTERVTTVAWAADNRTLFLTTEDDVTKRSDKLFRHVLGASAFDLLYEDKD
HHCCCCCCCCCCHHEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHCCCH
ELYDVTLGKTRDHQYLILLSESKDTSENLYLRASDPQGSFAVFLPRENKHRYYLDHRDGV
HEEEEECCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCCEEEEECCCCE
FYIRTNKTGKDFAVMTASAKDIAPKNWKPFIAHQEGVRIEEIDLFKEFAVSVEKTQALNR
EEEEECCCCCCEEEEEECCCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHCE
VRVYNFKTGAWTTVAFPEPVYSVFPGGTLDFDSITYRYSYQSLITPPSVFDYDTHTGKSA
EEEEEECCCCEEEEECCCCHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCHHH
LLKQQEVLGGYDPKQYASERLWATARDGVKVPISIVYKKGLVRDGKSPLFLYAYGSYGFG
HHHHHHHHCCCCHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCC
TPPNFSSNRLSLLDRGMTYAIAHIRGGDEMGEQWREDGMLMKKKNTFFDFIDCAEYLIKE
CCCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHH
KWTSAAGLVIEGGSAGGLLMGAVVNLRPDLFRAVHAAVPFVDVMNTMMDATLPLTVGEYL
HCCCCCCEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
EWGNPNEKPAYDYMKTYSPYDNLEKRGYPAILVTTSFHDSQVMYWEPAKYVARLRTVKTD
HCCCCCCCCHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHEECC
SNPLLLKIKMDPAGHGGASGRYDKLKDTAFEYAWMLSQVGRAK
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]