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The map label for this gene is iolG [H]

Identifier: 116622778

GI number: 116622778

Start: 4667111

End: 4668310

Strand: Reverse

Name: iolG [H]

Synonym: Acid_3677

Alternate gene names: 116622778

Gene position: 4668310-4667111 (Counterclockwise)

Preceding gene: 116622779

Following gene: 116622777

Centisome position: 46.84

GC content: 62.08

Gene sequence:

>1200_bases
ATGCCTGAAAATGATGTCCCACGCCGGACATTCCTGCGCGCTGCCAGCGCCGCCACTGCGCTTTCCTATTCCCGAGTCTA
TGGCGCGAATGAGCGCATTCAACTCGGCCTGATCGGCTGCGGCGAACGCGGCCGCTACGACATGGGCAATTTCGTCAAGA
GCGGCAAGGTGGATGTGGTCGCGCTCTGCGACATCTACGGCAACAATATCGACGCGGCCAAGACCACCGCGCCGAATGCC
AAGACCTTCGGCGATCATCGCAAGCTGCTCGAAACCAAGGAGGTCGATGTCGCCCTGATCGGCGTTCCCGACCACTGGCA
TGCCTCCTGCGCGATCGACGCCCTCAATGCCGGGAAGGACGTGTACGTCGAAAAGCCGCTGACGCTCAAGATTGACGAGG
GTCCGGAAATCGTGAAGGCCGCGCGCGTCAACAACCGCGTCTGCCAGGTCGGTATGCAGCAGCGCTCGGGCAAGCACTAC
ATCGAGGCGAAGCAGCTCTACGTGGATTCCGGCAAGCTCGGCAAGGTCACGCTCGCCCGCACGTGGTGGCACGGCAACGG
GTACCACCTTCGCAAGGCTCCGGCATCGCTGAAGGACCAGCCATCGAACCTCAACTGGTCGCGCTTCCTCGGGCCGCTCA
AGTGGCGCGACTGGGACCCGCAGCAGTATTGGAACTGGCGCGCCTACCTGGATTTCGGCGGCGGCCAGGTGACCGACCTG
TTCACGCACTGGATCGACGTGGTCCACATGTTCCTGGGGCAGGACATCCCGATTGCCGCTTCGGCCATCGGCGGCGTTTA
CAACTATAAGGACGGCCGCACCGCCCCGGACACGATTAACGTCCTGCTGGAATATCCGAAGGACCTCACCGCGACGTTCG
AAGCGACCCTGGTGCCCGGCGTCACCGGCGCGGGCATCGAATTCTGCGGCACTCTGGGCCGCCTCTACATCGATCGCGGA
CACTATACCTACACTCCGCTGGGCCGCAACGCGACGCCGATCGACGTCAAGGCATCCAGCAACATCGATCAGGATCACGT
CGAGAATTTCCTGGAATGCGTGAAGTCGCGCAATAAGCCGAATGGCGACGTCCTGGTGGGCCATCGCTCGGCGCAGGCCA
GCCATCTCGGCAACATCTCTTACATGCAGAAGCGGCGCATCGATTTCGACCCGGTACGTGAAGAGATACTCCCGTTTTAG

Upstream 100 bases:

>100_bases
ATTGCCTGCCCCACAATGCCGGGCCCCTCGAATGTTTGCGGCCTGCGAGCAGGCAAATGCACAGTAGTACAGAGGTGGCG
CGGGGGCATATAATCGACTC

Downstream 100 bases:

>100_bases
CGGGGGCTTCGGCCCCTGTTATACTAGAGTTTCTGTAGCGTCAACAACACATAGAGGAGTTTCATGATTTCAGCAACACA
ACTGCGTCCGGGAATGGTGA

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPENDVPRRTFLRAASAATALSYSRVYGANERIQLGLIGCGERGRYDMGNFVKSGKVDVVALCDIYGNNIDAAKTTAPNA
KTFGDHRKLLETKEVDVALIGVPDHWHASCAIDALNAGKDVYVEKPLTLKIDEGPEIVKAARVNNRVCQVGMQQRSGKHY
IEAKQLYVDSGKLGKVTLARTWWHGNGYHLRKAPASLKDQPSNLNWSRFLGPLKWRDWDPQQYWNWRAYLDFGGGQVTDL
FTHWIDVVHMFLGQDIPIAASAIGGVYNYKDGRTAPDTINVLLEYPKDLTATFEATLVPGVTGAGIEFCGTLGRLYIDRG
HYTYTPLGRNATPIDVKASSNIDQDHVENFLECVKSRNKPNGDVLVGHRSAQASHLGNISYMQKRRIDFDPVREEILPF

Sequences:

>Translated_399_residues
MPENDVPRRTFLRAASAATALSYSRVYGANERIQLGLIGCGERGRYDMGNFVKSGKVDVVALCDIYGNNIDAAKTTAPNA
KTFGDHRKLLETKEVDVALIGVPDHWHASCAIDALNAGKDVYVEKPLTLKIDEGPEIVKAARVNNRVCQVGMQQRSGKHY
IEAKQLYVDSGKLGKVTLARTWWHGNGYHLRKAPASLKDQPSNLNWSRFLGPLKWRDWDPQQYWNWRAYLDFGGGQVTDL
FTHWIDVVHMFLGQDIPIAASAIGGVYNYKDGRTAPDTINVLLEYPKDLTATFEATLVPGVTGAGIEFCGTLGRLYIDRG
HYTYTPLGRNATPIDVKASSNIDQDHVENFLECVKSRNKPNGDVLVGHRSAQASHLGNISYMQKRRIDFDPVREEILPF
>Mature_398_residues
PENDVPRRTFLRAASAATALSYSRVYGANERIQLGLIGCGERGRYDMGNFVKSGKVDVVALCDIYGNNIDAAKTTAPNAK
TFGDHRKLLETKEVDVALIGVPDHWHASCAIDALNAGKDVYVEKPLTLKIDEGPEIVKAARVNNRVCQVGMQQRSGKHYI
EAKQLYVDSGKLGKVTLARTWWHGNGYHLRKAPASLKDQPSNLNWSRFLGPLKWRDWDPQQYWNWRAYLDFGGGQVTDLF
THWIDVVHMFLGQDIPIAASAIGGVYNYKDGRTAPDTINVLLEYPKDLTATFEATLVPGVTGAGIEFCGTLGRLYIDRGH
YTYTPLGRNATPIDVKASSNIDQDHVENFLECVKSRNKPNGDVLVGHRSAQASHLGNISYMQKRRIDFDPVREEILPF

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 44477; Mature: 44346

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENDVPRRTFLRAASAATALSYSRVYGANERIQLGLIGCGERGRYDMGNFVKSGKVDVV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHCCCEEEE
ALCDIYGNNIDAAKTTAPNAKTFGDHRKLLETKEVDVALIGVPDHWHASCAIDALNAGKD
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHCCCCE
VYVEKPLTLKIDEGPEIVKAARVNNRVCQVGMQQRSGKHYIEAKQLYVDSGKLGKVTLAR
EEEECCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEEE
TWWHGNGYHLRKAPASLKDQPSNLNWSRFLGPLKWRDWDPQQYWNWRAYLDFGGGQVTDL
EEECCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHCCEEEEEECCCCHHHHH
FTHWIDVVHMFLGQDIPIAASAIGGVYNYKDGRTAPDTINVLLEYPKDLTATFEATLVPG
HHHHHHHHHHHHCCCCCCHHHHHCCCEECCCCCCCHHHHHHHHHCCCCCCEEEEEEECCC
VTGAGIEFCGTLGRLYIDRGHYTYTPLGRNATPIDVKASSNIDQDHVENFLECVKSRNKP
CCCCCHHHHHHHCEEEEECCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
NGDVLVGHRSAQASHLGNISYMQKRRIDFDPVREEILPF
CCCEEEEECCCCHHHCCCHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure 
PENDVPRRTFLRAASAATALSYSRVYGANERIQLGLIGCGERGRYDMGNFVKSGKVDVV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHCCCEEEE
ALCDIYGNNIDAAKTTAPNAKTFGDHRKLLETKEVDVALIGVPDHWHASCAIDALNAGKD
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHCCCCE
VYVEKPLTLKIDEGPEIVKAARVNNRVCQVGMQQRSGKHYIEAKQLYVDSGKLGKVTLAR
EEEECCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEEE
TWWHGNGYHLRKAPASLKDQPSNLNWSRFLGPLKWRDWDPQQYWNWRAYLDFGGGQVTDL
EEECCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHCCEEEEEECCCCHHHHH
FTHWIDVVHMFLGQDIPIAASAIGGVYNYKDGRTAPDTINVLLEYPKDLTATFEATLVPG
HHHHHHHHHHHHCCCCCCHHHHHCCCEECCCCCCCHHHHHHHHHCCCCCCEEEEEEECCC
VTGAGIEFCGTLGRLYIDRGHYTYTPLGRNATPIDVKASSNIDQDHVENFLECVKSRNKP
CCCCCHHHHHHHCEEEEECCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
NGDVLVGHRSAQASHLGNISYMQKRRIDFDPVREEILPF
CCCEEEEECCCCHHHCCCHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA