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The map label for this gene is dan [H]

Identifier: 116622724

GI number: 116622724

Start: 4584338

End: 4585924

Strand: Direct

Name: dan [H]

Synonym: Acid_3623

Alternate gene names: 116622724

Gene position: 4584338-4585924 (Clockwise)

Preceding gene: 116622723

Following gene: 116622725

Centisome position: 46.0

GC content: 64.21

Gene sequence:

>1587_bases
ATGGGCCGCATGGTTCGATGCGGCGTGGTGCTGTTGTTGGCGGCGGGACTCTGGGGGCAGGGGACTTCCTTTGATATCGT
CATCCGCGGGGCGCGGGTGGTGGATGGCTCCGGCTCGCCGTGGTTCTACTCCGACATCGGCATCCGCGGCGACACTATCG
CGCGGGTCGGCGATCTCTCGAGTGCGACTGCCGGGGTTACCATCGACGGGCACGGAATGGTTGTGGCGCCCGGCTTCATC
GACATTCACTCGCACGGGCGGCGCGGCATCATGCAGGTTCCTACGGCGGAAAACTACCTGCGTGAAGGGGTCACCACGAT
CGTGGAAGGACCGGACGGCAGTTCGCCGCTGCCGATTTCGGATTTCCTCGGCGGGATGCGGAAGACGCCGATCTCGGTGA
ATTTCGCAACCTTCGTGGGGCAGGGCAGCATCCGGCAGGCGGTAATCGGGTCGATCAATCGCAAGGCTACGCCGGAGGAG
CTCGCCAAGATGAAAGAGATGGCGGCGCAGGCGATGCGCGACGGCGCCTTCGGACTCTCCACGGGCCTGTTCTACGTGCC
CGGTAATTTTACGCCGACCGAAGAGGTGATCGAACTCGCCAAGGTGGTGGGCCGGATGGGCGGAATCCACATCTCGCATA
TGCGAGAGGAGGCCTCGCACGTGCTGGACAGCGTGCGCGAGACGATCCGCATCGGCGAGGAAGGCGGGCTGCCGACGCAG
ATCACCCACCATAAAATGATCGGGCAGCCGAGCTGGGGACAGAGCGTGGAATCGCTCAAGCTGGTGGAGGCGGCGCGAGC
ACGCGGCGTGGATGTGACGATCGACCAGTATCCTTATACCGCGTCGAGCACGGGGATCGCGGCGCTGGTGCCGCAGTGGG
CGCTCGAAGGCGGGCAGAAGGCCACTTCCGAGCGGCTGGCCGCGCCGGAGCAGCGCGCGCGCATCAAGAGCGCCATCGTG
AATAATCTCAAGGTGGACCGCGGGGCCGGCGATCCGAAGAATGTCTCGATCGTGAATTGCGGTTTCGACCGCACGCTGGC
GGGCAAGAACCTGACCGAGCTGACGATCGCGCGCGGGCAGGAGCCTAGCATGGAGAACGCCGCCGAGACCGTGATGGACC
TGGTCAACAAGGGCGGCTGCTCGGCCGTTTACCATGCGATCGCCGAAGAGGATGTGGTGCGCATCATGCGGTCGCCTTAC
ACGATGATCGCGTCCGATGGCGATATCCCGGTATTTGGGCAGGCGGCGCCGCACCCGCGCAGTTATGGGACTTTCGCGCG
AGTGCTCGGAGTGTATGTGCGCGAGAAGAACGTGATCACGCTCGAGGACGCTGTGCACAAGATGTCGGGCTATCCCGCCG
CACGTTTGAAGCTCTGGGATCGCGGGATGCTGCGTCCGGGGATGAAAGCCGACGTCATCGTGTTCGACCCGGCGACGGTG
GCGGACCGTGCCGAGTACAATAAGCCCCATCAGTATTCGGTGGGGATTCACGAGGTGATCGTCAACGGAAAGCTGGTGCT
GCACCAGGATAAGGTGACGGCGGAGAGGCCGGGACGTGTAATTGCGGGACCCTCGGCCGGGAGGTAA

Upstream 100 bases:

>100_bases
GCGGTTCGGATGGGGGCGGCGCGGATAGGGTGCGGCGCGGATACGTGCGGCGCGCCCCACAGAGCCGCGACCGCGAGGGA
GCGATCCTTGTCACGATACA

Downstream 100 bases:

>100_bases
GGTATGCCGGATATTTCGATCACGGACAATTTGGGCGCCCCGGTCGGGGTCAAGCTGGATCTCACGCAACCCTCGTCACT
GGTGGATTATGCGAAGGCCC

Product: dihydroorotase

Products: NA

Alternate protein names: N-acyl-D-amino-acid deacylase [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MGRMVRCGVVLLLAAGLWGQGTSFDIVIRGARVVDGSGSPWFYSDIGIRGDTIARVGDLSSATAGVTIDGHGMVVAPGFI
DIHSHGRRGIMQVPTAENYLREGVTTIVEGPDGSSPLPISDFLGGMRKTPISVNFATFVGQGSIRQAVIGSINRKATPEE
LAKMKEMAAQAMRDGAFGLSTGLFYVPGNFTPTEEVIELAKVVGRMGGIHISHMREEASHVLDSVRETIRIGEEGGLPTQ
ITHHKMIGQPSWGQSVESLKLVEAARARGVDVTIDQYPYTASSTGIAALVPQWALEGGQKATSERLAAPEQRARIKSAIV
NNLKVDRGAGDPKNVSIVNCGFDRTLAGKNLTELTIARGQEPSMENAAETVMDLVNKGGCSAVYHAIAEEDVVRIMRSPY
TMIASDGDIPVFGQAAPHPRSYGTFARVLGVYVREKNVITLEDAVHKMSGYPAARLKLWDRGMLRPGMKADVIVFDPATV
ADRAEYNKPHQYSVGIHEVIVNGKLVLHQDKVTAERPGRVIAGPSAGR

Sequences:

>Translated_528_residues
MGRMVRCGVVLLLAAGLWGQGTSFDIVIRGARVVDGSGSPWFYSDIGIRGDTIARVGDLSSATAGVTIDGHGMVVAPGFI
DIHSHGRRGIMQVPTAENYLREGVTTIVEGPDGSSPLPISDFLGGMRKTPISVNFATFVGQGSIRQAVIGSINRKATPEE
LAKMKEMAAQAMRDGAFGLSTGLFYVPGNFTPTEEVIELAKVVGRMGGIHISHMREEASHVLDSVRETIRIGEEGGLPTQ
ITHHKMIGQPSWGQSVESLKLVEAARARGVDVTIDQYPYTASSTGIAALVPQWALEGGQKATSERLAAPEQRARIKSAIV
NNLKVDRGAGDPKNVSIVNCGFDRTLAGKNLTELTIARGQEPSMENAAETVMDLVNKGGCSAVYHAIAEEDVVRIMRSPY
TMIASDGDIPVFGQAAPHPRSYGTFARVLGVYVREKNVITLEDAVHKMSGYPAARLKLWDRGMLRPGMKADVIVFDPATV
ADRAEYNKPHQYSVGIHEVIVNGKLVLHQDKVTAERPGRVIAGPSAGR
>Mature_527_residues
GRMVRCGVVLLLAAGLWGQGTSFDIVIRGARVVDGSGSPWFYSDIGIRGDTIARVGDLSSATAGVTIDGHGMVVAPGFID
IHSHGRRGIMQVPTAENYLREGVTTIVEGPDGSSPLPISDFLGGMRKTPISVNFATFVGQGSIRQAVIGSINRKATPEEL
AKMKEMAAQAMRDGAFGLSTGLFYVPGNFTPTEEVIELAKVVGRMGGIHISHMREEASHVLDSVRETIRIGEEGGLPTQI
THHKMIGQPSWGQSVESLKLVEAARARGVDVTIDQYPYTASSTGIAALVPQWALEGGQKATSERLAAPEQRARIKSAIVN
NLKVDRGAGDPKNVSIVNCGFDRTLAGKNLTELTIARGQEPSMENAAETVMDLVNKGGCSAVYHAIAEEDVVRIMRSPYT
MIASDGDIPVFGQAAPHPRSYGTFARVLGVYVREKNVITLEDAVHKMSGYPAARLKLWDRGMLRPGMKADVIVFDPATVA
DRAEYNKPHQYSVGIHEVIVNGKLVLHQDKVTAERPGRVIAGPSAGR

Specific function: Has a wide specificity; hydrolyzes N-acyl derivative of neutral D-amino acids [H]

COG id: COG3653

COG function: function code Q; N-acyl-D-aspartate/D-glutamate deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acyl-D-amino-acid deacylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR023100
- InterPro:   IPR012855
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3; PF07908 D-aminoacyl_C [H]

EC number: =3.5.1.81 [H]

Molecular weight: Translated: 56565; Mature: 56434

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRMVRCGVVLLLAAGLWGQGTSFDIVIRGARVVDGSGSPWFYSDIGIRGDTIARVGDLS
CCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCEEEECCCCCCCCHHHHCCCC
SATAGVTIDGHGMVVAPGFIDIHSHGRRGIMQVPTAENYLREGVTTIVEGPDGSSPLPIS
CCCCCEEECCCCEEEECCEEEECCCCCCCEEECCCHHHHHHCCCEEEEECCCCCCCCCHH
DFLGGMRKTPISVNFATFVGQGSIRQAVIGSINRKATPEELAKMKEMAAQAMRDGAFGLS
HHHCCHHCCCEEEEHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEC
TGLFYVPGNFTPTEEVIELAKVVGRMGGIHISHMREEASHVLDSVRETIRIGEEGGLPTQ
CCEEEECCCCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
ITHHKMIGQPSWGQSVESLKLVEAARARGVDVTIDQYPYTASSTGIAALVPQWALEGGQK
EHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCH
ATSERLAAPEQRARIKSAIVNNLKVDRGAGDPKNVSIVNCGFDRTLAGKNLTELTIARGQ
HHHHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCC
EPSMENAAETVMDLVNKGGCSAVYHAIAEEDVVRIMRSPYTMIASDGDIPVFGQAAPHPR
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCC
SYGTFARVLGVYVREKNVITLEDAVHKMSGYPAARLKLWDRGMLRPGMKADVIVFDPATV
CHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCHHHEEEHHCCCCCCCCCCCEEEECCCCH
ADRAEYNKPHQYSVGIHEVIVNGKLVLHQDKVTAERPGRVIAGPSAGR
HHHHHCCCCCEECCCHHHHEECCEEEEEECCCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
GRMVRCGVVLLLAAGLWGQGTSFDIVIRGARVVDGSGSPWFYSDIGIRGDTIARVGDLS
CCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCEEEECCCCCCCCHHHHCCCC
SATAGVTIDGHGMVVAPGFIDIHSHGRRGIMQVPTAENYLREGVTTIVEGPDGSSPLPIS
CCCCCEEECCCCEEEECCEEEECCCCCCCEEECCCHHHHHHCCCEEEEECCCCCCCCCHH
DFLGGMRKTPISVNFATFVGQGSIRQAVIGSINRKATPEELAKMKEMAAQAMRDGAFGLS
HHHCCHHCCCEEEEHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEC
TGLFYVPGNFTPTEEVIELAKVVGRMGGIHISHMREEASHVLDSVRETIRIGEEGGLPTQ
CCEEEECCCCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
ITHHKMIGQPSWGQSVESLKLVEAARARGVDVTIDQYPYTASSTGIAALVPQWALEGGQK
EHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCH
ATSERLAAPEQRARIKSAIVNNLKVDRGAGDPKNVSIVNCGFDRTLAGKNLTELTIARGQ
HHHHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCC
EPSMENAAETVMDLVNKGGCSAVYHAIAEEDVVRIMRSPYTMIASDGDIPVFGQAAPHPR
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCC
SYGTFARVLGVYVREKNVITLEDAVHKMSGYPAARLKLWDRGMLRPGMKADVIVFDPATV
CHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCHHHEEEHHCCCCCCCCCCCEEEECCCCH
ADRAEYNKPHQYSVGIHEVIVNGKLVLHQDKVTAERPGRVIAGPSAGR
HHHHHCCCCCEECCCHHHHEECCEEEEEECCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8541651 [H]