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The map label for this gene is nuoA1 [H]

Identifier: 116622681

GI number: 116622681

Start: 4531129

End: 4531485

Strand: Direct

Name: nuoA1 [H]

Synonym: Acid_3580

Alternate gene names: 116622681

Gene position: 4531129-4531485 (Clockwise)

Preceding gene: 116622673

Following gene: 116622682

Centisome position: 45.47

GC content: 55.74

Gene sequence:

>357_bases
ATGCCTAGCGGCTACCTTCCGATTTTCATCTTTTTGGCAATCGCGATCAGCTTCCCCGTTGTGGCGATCGTGGCGGCAAA
ACTGATCCGGCCATCGGCTCCGTTTGCTGCCAAGCTGGAAGCCTACGAATGCGGTATCAAGGCCGCGTCGGATTCGCGCG
GGCGCTACACGGTGCGCTTCTACATCATCGCCATCCTTTTTGTCATCTTCGATGTGGAGACGATCTTCTTATTCCCCTGG
GCCGTACGCTATCGTCAGATGCAATGGTTCGGCGTGGCCGAAGTTGCCGTGTTTCTGGTGATCCTCGCGGTCGGTTATAT
CTGGGCGTATAAGAAGGGTGCTCTCGAGTGGGTCTAA

Upstream 100 bases:

>100_bases
GGTTGTGCCGTACCGGGTACCGATATAAGGAATTTCCCAGGAAATCGGCTTGCGTCCGGCATTTATCCAGTCCCGCGGAA
CGCGTGTTATAGTGAGGCTC

Downstream 100 bases:

>100_bases
ATCAACGTTGTTCCCTGGCGTTCACCGCCGCAGTCCTTCTTTCCACAGGTGTTCTGAGCGCGGCTCCCCGTCTCCGCCTG
GTTTCCAGTACCGTCGGACC

Product: NADH-ubiquinone/plastoquinone oxidoreductase subunit 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1 [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MPSGYLPIFIFLAIAISFPVVAIVAAKLIRPSAPFAAKLEAYECGIKAASDSRGRYTVRFYIIAILFVIFDVETIFLFPW
AVRYRQMQWFGVAEVAVFLVILAVGYIWAYKKGALEWV

Sequences:

>Translated_118_residues
MPSGYLPIFIFLAIAISFPVVAIVAAKLIRPSAPFAAKLEAYECGIKAASDSRGRYTVRFYIIAILFVIFDVETIFLFPW
AVRYRQMQWFGVAEVAVFLVILAVGYIWAYKKGALEWV
>Mature_117_residues
PSGYLPIFIFLAIAISFPVVAIVAAKLIRPSAPFAAKLEAYECGIKAASDSRGRYTVRFYIIAILFVIFDVETIFLFPWA
VRYRQMQWFGVAEVAVFLVILAVGYIWAYKKGALEWV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=109, Percent_Identity=34.8623853211009, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13333; Mature: 13202

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSGYLPIFIFLAIAISFPVVAIVAAKLIRPSAPFAAKLEAYECGIKAASDSRGRYTVRF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHH
YIIAILFVIFDVETIFLFPWAVRYRQMQWFGVAEVAVFLVILAVGYIWAYKKGALEWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PSGYLPIFIFLAIAISFPVVAIVAAKLIRPSAPFAAKLEAYECGIKAASDSRGRYTVRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHH
YIIAILFVIFDVETIFLFPWAVRYRQMQWFGVAEVAVFLVILAVGYIWAYKKGALEWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]