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The map label for this gene is gltD [H]

Identifier: 116622612

GI number: 116622612

Start: 4441400

End: 4443415

Strand: Direct

Name: gltD [H]

Synonym: Acid_3510

Alternate gene names: 116622612

Gene position: 4441400-4443415 (Clockwise)

Preceding gene: 116622611

Following gene: 116622613

Centisome position: 44.57

GC content: 66.72

Gene sequence:

>2016_bases
ATGCCTTTCATAACCAACGAGCCGCGACCGTCAGGGAGCCCTACCCGCACATCATCCGCCGTAACGCTCCCTGACGGTCG
CGGCTCGTTTCAGCTCCGCGTCCCCGATGCCACCGATTACTGGGTGGAAATGGTCAAGTGTCGCCACGCCTGCCCGGTCC
ACACCGACGCCTGCGGCTACGTCAACGCCATCGCCGAAGGCCGCCCCGAAGACGCCTACCGCATCGCTCGCGCCACCAAT
CCCTTCACCTCCATCTGCGGCCGCGTCTGCGGCGCCCCCTGCGAAGCCAACTGCCGCCGCGGCGATCTCGACGCCCCCGT
CGCCATACGCGCCCTCAAGCGCTTCGTCAACGAGCAGTTCGGCCCCGAGACCGGCGACTATCGCCTCCACCGCGAAGCCG
GCGATTCCCGCATGCTCCCGCCCAACCGGGGCGATTACGAACGCGTCGCCATCGTCGGCGCCGGTGTCGCCGGACTCACG
GTCGCCCACGATCTCGCCCAAATCGGCTACAAGGTCACCGTCTTCGAAGCCCACTCGGAACCCGGCGGCATGCTGATGGT
CGGCGTCCCCGTCTTCCGCCTCCCGCGCGATCTCGTCCGCCACGAAATCCAGGCCATCCTCTCCCTCGGCGTCGAGCTTC
GCTGCAACGTCCGCCTCGGCCGTGACTTCACCATCGCCAGCCTCCGCCAGGATGGCTACAAGGCCATCTTCCTCGGCATG
GGCCTCCAGAAGGGCCGCAAACTCCCGCTCCCCGGCGCCGACCTGGAAGGCGTCTACGACGGCATGGATTTCCTGCGCGC
CTTCAACGAGGGCCGCTCCCTCCCGTTGGGCCGCCGCGTCATCGTCATCGGCGGCGGCAACGTCGCCTACGACGTCGCCC
GTTCCGCACTCCGCCCCGACAACGATCACATGGCCTACGATGTCGCGCGCGCCGCCCTGCGCTTGTCCGGCGACAAGGAA
GTCCACGTTGTCTGCCTCGAAAGCCGCGAGGAAATGCCCGCCGACGCCATCGAGATCCACGAAGGCGAGGAGGAGGGCAT
TGTCCTCCACAACCGCCGCGGCCCGCGCGCCGTCATCGAAGAAAACGGCAAAGCCGCCGGCCTGCGCGTCACCCACTGCA
CCTCGGTCTTCGATGCCGAAGGTCGCTTCAATCCCCAGTTCGACGAATCGCACGTCGAGGACATCGCCGCCGACAGCGTG
ATCTTCGCCATCGGCCAGACCTCCGACCTCTCCTTCCTTACCCCCGAAGACGGCGTCGATACGGCGCGCGGCCTCATCAA
GGTGAATCCTGAAACCTACCAGACCACCGCTCCCGATATCTTCGCCTGCGGCGACATCGCCCACGGCGCGCGCCTCTTCA
TCGACGCCATCGCTTCCGCCCAGATCGCCGCCCGCTCGATGCACGATTTCCTCCGCGGCACCCGCACCGACGTCGTTCTG
CGCAAGCACTGGAAGCCCGCCTCCTACAACATGGCCGAGGGCTGGAACCGCTTCGACCGCGAAAATCCGCCGGTCATCGA
TTCCGAACGCCGCGCCGCCTCGCTCGAGATCATCGAATGCGTCTACAGCGAAAACGACGCCCGCCGCCAGGCCGCCCGCT
GCCTGCGCTGCAACGTGAACACGGTCTTCGATACCAAAATCTGCATCGCCTGCAACGGCTGCGTCGATGTCTGCCCCGAA
AACCTGATCCGCCTCGTCGGCCTCAGCAAACTCATCTCCGACGACCACTGGCTCGAAACCGCCGCCGCCAATTTCGGCGT
GGAGCCCGACGATCTCCGCGCCCTCCCGCCCGAAGAGCTCGACACCTTCGGCGGCGTCATGATGAAGGACGAAACCACCT
GCATCCGCTGCGCCATGTGTGCCTCCCGCTGCCCCACCCACGCCATCCTGATGAAGCACTTCGTCTTCCACCGCGAGTGC
GTCACCGTCCCCACGGTCAACACCAAGCTCCTGCCTGGTGGGGCAGCCAATCCTGGCTGCAGCCGGCTTCCAGCCGGCTC
CCGGAGCGCGACGTGA

Upstream 100 bases:

>100_bases
CAGCGACACCTTCATGTACATCGTCGCCGCCCTCGCCGCCGCCTTCGTCGTCACGGTGCTCGCCTTCACCTACAGCAAAC
CGCACGGAGACTAACTCGCG

Downstream 100 bases:

>100_bases
CCCCGTTCGACCTCACCCTCCCGCTCGCCCTCGGCCTGGTCAGCAGCCTCCACTGCGCCCAGATGTGCGGCCCCATCGTC
CTTTCCTACAGCATGGCCGG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: Glutamate synthase subunit beta; GLTS beta chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MPFITNEPRPSGSPTRTSSAVTLPDGRGSFQLRVPDATDYWVEMVKCRHACPVHTDACGYVNAIAEGRPEDAYRIARATN
PFTSICGRVCGAPCEANCRRGDLDAPVAIRALKRFVNEQFGPETGDYRLHREAGDSRMLPPNRGDYERVAIVGAGVAGLT
VAHDLAQIGYKVTVFEAHSEPGGMLMVGVPVFRLPRDLVRHEIQAILSLGVELRCNVRLGRDFTIASLRQDGYKAIFLGM
GLQKGRKLPLPGADLEGVYDGMDFLRAFNEGRSLPLGRRVIVIGGGNVAYDVARSALRPDNDHMAYDVARAALRLSGDKE
VHVVCLESREEMPADAIEIHEGEEEGIVLHNRRGPRAVIEENGKAAGLRVTHCTSVFDAEGRFNPQFDESHVEDIAADSV
IFAIGQTSDLSFLTPEDGVDTARGLIKVNPETYQTTAPDIFACGDIAHGARLFIDAIASAQIAARSMHDFLRGTRTDVVL
RKHWKPASYNMAEGWNRFDRENPPVIDSERRAASLEIIECVYSENDARRQAARCLRCNVNTVFDTKICIACNGCVDVCPE
NLIRLVGLSKLISDDHWLETAAANFGVEPDDLRALPPEELDTFGGVMMKDETTCIRCAMCASRCPTHAILMKHFVFHREC
VTVPTVNTKLLPGGAANPGCSRLPAGSRSAT

Sequences:

>Translated_671_residues
MPFITNEPRPSGSPTRTSSAVTLPDGRGSFQLRVPDATDYWVEMVKCRHACPVHTDACGYVNAIAEGRPEDAYRIARATN
PFTSICGRVCGAPCEANCRRGDLDAPVAIRALKRFVNEQFGPETGDYRLHREAGDSRMLPPNRGDYERVAIVGAGVAGLT
VAHDLAQIGYKVTVFEAHSEPGGMLMVGVPVFRLPRDLVRHEIQAILSLGVELRCNVRLGRDFTIASLRQDGYKAIFLGM
GLQKGRKLPLPGADLEGVYDGMDFLRAFNEGRSLPLGRRVIVIGGGNVAYDVARSALRPDNDHMAYDVARAALRLSGDKE
VHVVCLESREEMPADAIEIHEGEEEGIVLHNRRGPRAVIEENGKAAGLRVTHCTSVFDAEGRFNPQFDESHVEDIAADSV
IFAIGQTSDLSFLTPEDGVDTARGLIKVNPETYQTTAPDIFACGDIAHGARLFIDAIASAQIAARSMHDFLRGTRTDVVL
RKHWKPASYNMAEGWNRFDRENPPVIDSERRAASLEIIECVYSENDARRQAARCLRCNVNTVFDTKICIACNGCVDVCPE
NLIRLVGLSKLISDDHWLETAAANFGVEPDDLRALPPEELDTFGGVMMKDETTCIRCAMCASRCPTHAILMKHFVFHREC
VTVPTVNTKLLPGGAANPGCSRLPAGSRSAT
>Mature_670_residues
PFITNEPRPSGSPTRTSSAVTLPDGRGSFQLRVPDATDYWVEMVKCRHACPVHTDACGYVNAIAEGRPEDAYRIARATNP
FTSICGRVCGAPCEANCRRGDLDAPVAIRALKRFVNEQFGPETGDYRLHREAGDSRMLPPNRGDYERVAIVGAGVAGLTV
AHDLAQIGYKVTVFEAHSEPGGMLMVGVPVFRLPRDLVRHEIQAILSLGVELRCNVRLGRDFTIASLRQDGYKAIFLGMG
LQKGRKLPLPGADLEGVYDGMDFLRAFNEGRSLPLGRRVIVIGGGNVAYDVARSALRPDNDHMAYDVARAALRLSGDKEV
HVVCLESREEMPADAIEIHEGEEEGIVLHNRRGPRAVIEENGKAAGLRVTHCTSVFDAEGRFNPQFDESHVEDIAADSVI
FAIGQTSDLSFLTPEDGVDTARGLIKVNPETYQTTAPDIFACGDIAHGARLFIDAIASAQIAARSMHDFLRGTRTDVVLR
KHWKPASYNMAEGWNRFDRENPPVIDSERRAASLEIIECVYSENDARRQAARCLRCNVNTVFDTKICIACNGCVDVCPEN
LIRLVGLSKLISDDHWLETAAANFGVEPDDLRALPPEELDTFGGVMMKDETTCIRCAMCASRCPTHAILMKHFVFHRECV
TVPTVNTKLLPGGAANPGCSRLPAGSRSAT

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=472, Percent_Identity=27.7542372881356, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI111118981, Length=208, Percent_Identity=30.2884615384615, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI111118983, Length=214, Percent_Identity=29.9065420560748, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789606, Length=447, Percent_Identity=30.6487695749441, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1789243, Length=515, Percent_Identity=29.126213592233, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788468, Length=430, Percent_Identity=30.4651162790698, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1788811, Length=447, Percent_Identity=31.0961968680089, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI87082180, Length=450, Percent_Identity=29.3333333333333, Blast_Score=165, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71984108, Length=452, Percent_Identity=26.7699115044248, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17570289, Length=462, Percent_Identity=24.2424242424242, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17543860, Length=220, Percent_Identity=30.4545454545455, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320030, Length=418, Percent_Identity=25.8373205741627, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24665547, Length=457, Percent_Identity=27.5711159737418, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24665543, Length=457, Percent_Identity=27.5711159737418, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI28574881, Length=457, Percent_Identity=27.5711159737418, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24665539, Length=457, Percent_Identity=27.5711159737418, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24640763, Length=455, Percent_Identity=27.9120879120879, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18858217, Length=455, Percent_Identity=27.9120879120879, Blast_Score=132, Evalue=1e-30,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006
- InterPro:   IPR009051
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 73366; Mature: 73235

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFITNEPRPSGSPTRTSSAVTLPDGRGSFQLRVPDATDYWVEMVKCRHACPVHTDACGY
CCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHH
VNAIAEGRPEDAYRIARATNPFTSICGRVCGAPCEANCRRGDLDAPVAIRALKRFVNEQF
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GPETGDYRLHREAGDSRMLPPNRGDYERVAIVGAGVAGLTVAHDLAQIGYKVTVFEAHSE
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCEEEEEEEECCC
PGGMLMVGVPVFRLPRDLVRHEIQAILSLGVELRCNVRLGRDFTIASLRQDGYKAIFLGM
CCCEEEECCCHHHCCHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEHHHCCCCEEEEEEC
GLQKGRKLPLPGADLEGVYDGMDFLRAFNEGRSLPLGRRVIVIGGGNVAYDVARSALRPD
CHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCC
NDHMAYDVARAALRLSGDKEVHVVCLESREEMPADAIEIHEGEEEGIVLHNRRGPRAVIE
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCCHHHH
ENGKAAGLRVTHCTSVFDAEGRFNPQFDESHVEDIAADSVIFAIGQTSDLSFLTPEDGVD
CCCCCCCEEEEEECCEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCCC
TARGLIKVNPETYQTTAPDIFACGDIAHGARLFIDAIASAQIAARSMHDFLRGTRTDVVL
CCCCEEEECCCCCCCCCCCEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEE
RKHWKPASYNMAEGWNRFDRENPPVIDSERRAASLEIIECVYSENDARRQAARCLRCNVN
HCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
TVFDTKICIACNGCVDVCPENLIRLVGLSKLISDDHWLETAAANFGVEPDDLRALPPEEL
EEECCEEEEEECCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCCHHHH
DTFGGVMMKDETTCIRCAMCASRCPTHAILMKHFVFHRECVTVPTVNTKLLPGGAANPGC
HHHCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCC
SRLPAGSRSAT
CCCCCCCCCCC
>Mature Secondary Structure 
PFITNEPRPSGSPTRTSSAVTLPDGRGSFQLRVPDATDYWVEMVKCRHACPVHTDACGY
CCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHH
VNAIAEGRPEDAYRIARATNPFTSICGRVCGAPCEANCRRGDLDAPVAIRALKRFVNEQF
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GPETGDYRLHREAGDSRMLPPNRGDYERVAIVGAGVAGLTVAHDLAQIGYKVTVFEAHSE
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCEEEEEEEECCC
PGGMLMVGVPVFRLPRDLVRHEIQAILSLGVELRCNVRLGRDFTIASLRQDGYKAIFLGM
CCCEEEECCCHHHCCHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEHHHCCCCEEEEEEC
GLQKGRKLPLPGADLEGVYDGMDFLRAFNEGRSLPLGRRVIVIGGGNVAYDVARSALRPD
CHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCC
NDHMAYDVARAALRLSGDKEVHVVCLESREEMPADAIEIHEGEEEGIVLHNRRGPRAVIE
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCCHHHH
ENGKAAGLRVTHCTSVFDAEGRFNPQFDESHVEDIAADSVIFAIGQTSDLSFLTPEDGVD
CCCCCCCEEEEEECCEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCCC
TARGLIKVNPETYQTTAPDIFACGDIAHGARLFIDAIASAQIAARSMHDFLRGTRTDVVL
CCCCEEEECCCCCCCCCCCEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEE
RKHWKPASYNMAEGWNRFDRENPPVIDSERRAASLEIIECVYSENDARRQAARCLRCNVN
HCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
TVFDTKICIACNGCVDVCPENLIRLVGLSKLISDDHWLETAAANFGVEPDDLRALPPEEL
EEECCEEEEEECCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCCHHHH
DTFGGVMMKDETTCIRCAMCASRCPTHAILMKHFVFHRECVTVPTVNTKLLPGGAANPGC
HHHCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCC
SRLPAGSRSAT
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3326786; 9278503; 9298646; 9600841; 2643092 [H]