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The map label for this gene is 116622566

Identifier: 116622566

GI number: 116622566

Start: 4380885

End: 4382252

Strand: Reverse

Name: 116622566

Synonym: Acid_3464

Alternate gene names: NA

Gene position: 4382252-4380885 (Counterclockwise)

Preceding gene: 116622568

Following gene: 116622565

Centisome position: 43.97

GC content: 62.28

Gene sequence:

>1368_bases
GTGGGGAGGGAGTTCATTGCGCTTCCGGTTGCCGCTGCAAAGCGCGATATGCTTTCTAGTGACATGAATCGACGTAGCTT
TTTGCAGGCCGCATCGGCGCTGCCGCTCATGCAGGTTGGACGCGCGCAACTTGCCACTGCGCCGCGTTTCGGGGATGGAC
GCGACTGGTGGTTTGAGAAGCGCTTCGGCATGTTCATCCACTGGGGACTGTATGCAATCCACGGGTTGCACGAGCAGGAG
CAGTGGCGGTATCGGGTGCCGCGCGCGGAGTACGAGACGCTGGCCAAACAATGGAATCCGGTGAAGTACGATCCTAATAC
CTGGCTCGACCTGGCGGCGGCAGCGGGGATGAAGTACGTCTGCCTCACCACCAAGCATCACGATGGCTTCTGCCTCTGGG
ATACAAAGCAGACCACCTACAATACGATGAACACGCCGTACGGCAAGGACGTGGTGAAGATGCTGGCTGACGCCTGCCAT
CGACGCGGCGTGCCGCTCTGCCTCTACTATTCGATCGCCGACTGGCATCAGCCCAACTATCCCAACCAGGGCCGCTCGCA
CGAGTTGCCGCCGCAGGCCGGCGATCAGCCCGACTTCGCCCGCTACCTGGACTTCCTCAAGGCGCAGGTGCGTGAGCTCT
GCACCAACTACGGCGAACTCGGCGGCATCTGGTGGGATATGAACGTCCCGAAGCACGTGGACCGCTCCGTCAACGACATG
ATCCGCACGCTGCAGCCCAAGGCGGTGATCAACAATCGCGGCTTCGACGACGGCGATTTCGGCACGCCGGAGCGCGATTA
CGAGACCACCGGTGAAGAGCTGTTGACTTTCGCGCAGCGCACCGAAGCCTGCCAGAGCGTGGGCAGCGAATCCTGGGGCT
ACCGGCGGAACGAGGATTATTACACGGACCGCCACCTGATCCGCAGCATCGATAAATACCTGGCGCGCGACGCGAACTAC
CTGCTCAACGTGGGTCCGGCGCCCGATGGCACAATCCCGGCGCGGCCTTCGGAGATTCTCAAGCGCATCGGCAAGTGGTA
CGGCGCGGTCAGGGAATCGGTGGAAGGCACGGCGCCGGCCTCGAACCTGACGACCAATCGCAGCGTGATGCTGACGCGGC
GCGACAACACGATCTACGTCCATTTAAATAAGGACCCGATTCGGGAAGCGGTACAACTCAGGCCGATCGCGGTGATGCCG
CGGCGCGCCACGCTGCTGAACACTGGGCGGCCCGCCGAATGCGTGGTGGAGATGGCGCCGAGCGACCACATCGAGCACAA
GCCGTTCCTGCGCATTCGCAATCTGCCGGTGGACGAAATGGCGGACACGGTGCTGGTGGTAAAGCTGGAGTTCGACAGGC
TGTCGTGA

Upstream 100 bases:

>100_bases
AACGCGAGGCCGGCGCCCTTCAAGAAGTCTCGCCGTTCCATGGCTACAGGCTACACCTAAATGACGCTCCCTGACGGTCG
CGGCCCTGATGGAGCGGCGA

Downstream 100 bases:

>100_bases
CATGCCGGAACTTCCCGATGTGGTGGTGTATGTAGAAGCGCTCTGCGCCCGGATCGCCGGCCACACGCTGACCCGCGTGA
CGTTGCGCGGACCGTTCCTG

Product: glycoside hydrolase family alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Coagulation Factor 5/8 Type Domain Protein; Calx-Beta Domain-Containing Protein; Exported Alpha-L-Fucosidase Protein; Alpha-1 3/4-Fucosidase; Alpha-L-Fucosidase Protein; Lipoprotein; Exporte Hydrolase; Exported Fucosidase; Alpha-L-Fucosidase Family Protein; Coagulation Factor 5/8 Type Domain-Containing Protein; Alpha-L-Fucosidase-Like Protein; Glycoside Hydrolase Family Alpha-L-Fucosidase; Ig Domain-Containing; Twin-Arginine Translocation Pathway Signal; Fucosidase; Tat Pathway Signal Sequence Domain Protein; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; DS Domain-Containing Protein; Glycoside Hydrolase

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MGREFIALPVAAAKRDMLSSDMNRRSFLQAASALPLMQVGRAQLATAPRFGDGRDWWFEKRFGMFIHWGLYAIHGLHEQE
QWRYRVPRAEYETLAKQWNPVKYDPNTWLDLAAAAGMKYVCLTTKHHDGFCLWDTKQTTYNTMNTPYGKDVVKMLADACH
RRGVPLCLYYSIADWHQPNYPNQGRSHELPPQAGDQPDFARYLDFLKAQVRELCTNYGELGGIWWDMNVPKHVDRSVNDM
IRTLQPKAVINNRGFDDGDFGTPERDYETTGEELLTFAQRTEACQSVGSESWGYRRNEDYYTDRHLIRSIDKYLARDANY
LLNVGPAPDGTIPARPSEILKRIGKWYGAVRESVEGTAPASNLTTNRSVMLTRRDNTIYVHLNKDPIREAVQLRPIAVMP
RRATLLNTGRPAECVVEMAPSDHIEHKPFLRIRNLPVDEMADTVLVVKLEFDRLS

Sequences:

>Translated_455_residues
MGREFIALPVAAAKRDMLSSDMNRRSFLQAASALPLMQVGRAQLATAPRFGDGRDWWFEKRFGMFIHWGLYAIHGLHEQE
QWRYRVPRAEYETLAKQWNPVKYDPNTWLDLAAAAGMKYVCLTTKHHDGFCLWDTKQTTYNTMNTPYGKDVVKMLADACH
RRGVPLCLYYSIADWHQPNYPNQGRSHELPPQAGDQPDFARYLDFLKAQVRELCTNYGELGGIWWDMNVPKHVDRSVNDM
IRTLQPKAVINNRGFDDGDFGTPERDYETTGEELLTFAQRTEACQSVGSESWGYRRNEDYYTDRHLIRSIDKYLARDANY
LLNVGPAPDGTIPARPSEILKRIGKWYGAVRESVEGTAPASNLTTNRSVMLTRRDNTIYVHLNKDPIREAVQLRPIAVMP
RRATLLNTGRPAECVVEMAPSDHIEHKPFLRIRNLPVDEMADTVLVVKLEFDRLS
>Mature_454_residues
GREFIALPVAAAKRDMLSSDMNRRSFLQAASALPLMQVGRAQLATAPRFGDGRDWWFEKRFGMFIHWGLYAIHGLHEQEQ
WRYRVPRAEYETLAKQWNPVKYDPNTWLDLAAAAGMKYVCLTTKHHDGFCLWDTKQTTYNTMNTPYGKDVVKMLADACHR
RGVPLCLYYSIADWHQPNYPNQGRSHELPPQAGDQPDFARYLDFLKAQVRELCTNYGELGGIWWDMNVPKHVDRSVNDMI
RTLQPKAVINNRGFDDGDFGTPERDYETTGEELLTFAQRTEACQSVGSESWGYRRNEDYYTDRHLIRSIDKYLARDANYL
LNVGPAPDGTIPARPSEILKRIGKWYGAVRESVEGTAPASNLTTNRSVMLTRRDNTIYVHLNKDPIREAVQLRPIAVMPR
RATLLNTGRPAECVVEMAPSDHIEHKPFLRIRNLPVDEMADTVLVVKLEFDRLS

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI119360348, Length=387, Percent_Identity=25.5813953488372, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI40068512, Length=416, Percent_Identity=25.4807692307692, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71997700, Length=369, Percent_Identity=24.6612466124661, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24662717, Length=359, Percent_Identity=27.5766016713092, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI78706642, Length=359, Percent_Identity=27.5766016713092, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 52256; Mature: 52125

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGREFIALPVAAAKRDMLSSDMNRRSFLQAASALPLMQVGRAQLATAPRFGDGRDWWFEK
CCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCHHHHHCCCCCCCCCCHHHHH
RFGMFIHWGLYAIHGLHEQEQWRYRVPRAEYETLAKQWNPVKYDPNTWLDLAAAAGMKYV
HCCHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEE
CLTTKHHDGFCLWDTKQTTYNTMNTPYGKDVVKMLADACHRRGVPLCLYYSIADWHQPNY
EEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCC
PNQGRSHELPPQAGDQPDFARYLDFLKAQVRELCTNYGELGGIWWDMNVPKHVDRSVNDM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHHHH
IRTLQPKAVINNRGFDDGDFGTPERDYETTGEELLTFAQRTEACQSVGSESWGYRRNEDY
HHHCCCHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YTDRHLIRSIDKYLARDANYLLNVGPAPDGTIPARPSEILKRIGKWYGAVRESVEGTAPA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
SNLTTNRSVMLTRRDNTIYVHLNKDPIREAVQLRPIAVMPRRATLLNTGRPAECVVEMAP
CCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCEEECCCCHHEECCCCCHHHEEEECC
SDHIEHKPFLRIRNLPVDEMADTVLVVKLEFDRLS
CCCCCCCCCEEECCCCHHHHCCEEEEEEEECCCCC
>Mature Secondary Structure 
GREFIALPVAAAKRDMLSSDMNRRSFLQAASALPLMQVGRAQLATAPRFGDGRDWWFEK
CCCEEEECHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCHHHHHCCCCCCCCCCHHHHH
RFGMFIHWGLYAIHGLHEQEQWRYRVPRAEYETLAKQWNPVKYDPNTWLDLAAAAGMKYV
HCCHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEE
CLTTKHHDGFCLWDTKQTTYNTMNTPYGKDVVKMLADACHRRGVPLCLYYSIADWHQPNY
EEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCC
PNQGRSHELPPQAGDQPDFARYLDFLKAQVRELCTNYGELGGIWWDMNVPKHVDRSVNDM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHHHH
IRTLQPKAVINNRGFDDGDFGTPERDYETTGEELLTFAQRTEACQSVGSESWGYRRNEDY
HHHCCCHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YTDRHLIRSIDKYLARDANYLLNVGPAPDGTIPARPSEILKRIGKWYGAVRESVEGTAPA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
SNLTTNRSVMLTRRDNTIYVHLNKDPIREAVQLRPIAVMPRRATLLNTGRPAECVVEMAP
CCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCEEECCCCHHEECCCCCHHHEEEECC
SDHIEHKPFLRIRNLPVDEMADTVLVVKLEFDRLS
CCCCCCCCCEEECCCCHHHHCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA