Click here to switch to the map view.

The map label for this gene is icfG [H]

Identifier: 116622534

GI number: 116622534

Start: 4340624

End: 4342258

Strand: Reverse

Name: icfG [H]

Synonym: Acid_3432

Alternate gene names: 116622534

Gene position: 4342258-4340624 (Counterclockwise)

Preceding gene: 116622535

Following gene: 116622533

Centisome position: 43.57

GC content: 63.12

Gene sequence:

>1635_bases
ATGTCTCGTGAACTCCTCATCCAGTGTCCGGATGGGCAGATGAAAACCGTGCCCCTCACCGGCGGCCGCCTTTCCATCGG
CCGCTCCAGCGCCGCCGAGCTTTGCTTTCCGGAGGACGCCGGCCTCTCACGCCAGCACTTCGCCTTTGAGCCGGAAGGCG
AGGATTGGACAGTGCAGGACCTGGGCAGCAAGAACGGTACCTTCGTCAACAACATCCCCCTCAAGGCCCGCCTGATCCTC
AAGCCCGGCGATCGCGTCACCGCCGGCCACCTGGTCATCGTATACTCGCCGGACGCCGTGGACCCAGCTGCCGGCGTAGT
GGTCTTCGAAGGCGAAACCAGCTCGCCCACCACGTCCACCGTGGTCACCAGCCTGGAGGGCGCGCTCTCCAACCAGACTA
TGGCGATCGAGCGCGGCGGCCCCAAGGCATCCGCGCCCATGCAGGCGCTGATCCGCGCAGGCCTGGAACTCAGCGAGAAT
CGTCCGCTGAACGAACTCTTTCCCGTCATACTCGATCTTTCCATTCAGGCCGTGAACGCGCAGCGCGGCGTGCTCATGAT
TCTGGACGGCGATCAGCTCATTCCGCGCGCCCACAAGGGCGACGGCTTCCGCATCTCCACCGCCGTCCGCGACAAAGTGC
TTAAGGAGCGCTCCTCCATCCTGGTGCGCGACGCCCAGCTCGATGACGCCTTCAAAGGTCGCATGAGCATCGTCGAGCAA
AAGGTCCATACCATGATGGCCGCCCCGCTGCAGAACAAAGATCGCATTATCGGCCTGATTTACCTGGATTCCCCGTTCAT
CCTTCGCGAGTTCACCAAGGACGATCTGAACCTCCTGACCGTGATGGCCAACATCGCGGCTGCGCGCATTGAGAACGCCC
GCCTCGCCGAGGTCGAGCAGGCCGAGCGCATCATGGCGCGCGACCTTTCGCAGGCCGGTGTGATTCAGAGCGGCATGCTG
CCCGATAAGGCCCCGGACGTTCCCGGCGCCGATCTTGCCGGCTTCAACATGGCCTGCCGCACCGTGGGCGGCGACTACTA
CGATTTCTTCAAGTACCCCGATGGCCGGGTCGCCCTCGCGCTCGGCGACGTATCAGGCAAGGGCATGCCCGCATCGCTCA
TCATGATGCAGTTACATGCCCGCGTTCAGGTGCTGGCCGAAGACCCCGGCAATCTCGCCCAGTTTATGACGCGCATCAAC
AAGGCCACCTGCGCCAAGTGTCCCAGCAACCGCTTCATCACATTCTTCTTCTCCGTGCTCAACGCAGCCACCGGCGAACT
GGCTTACGCCAACGCGGGACACAATCCGCCGATCCTGGTGCGTGCCAATGGCGATGCCGAAATGCTCGAAGGCGGCGGCC
CCGTGCTCGGCATTCTCCCCATCGCGCCCTACAGCGAAATGCACGCCCATCTGGACCGCGGCGATATGATCGCGATCTAC
AGCGATGGCGTCACCGAAGCCAACAACGTGGCTTACGACGAGTTCGATGAAGAACGCCTGATCGAAGTCCTCAAGGCCAA
CCGCCACGAGCCGGCCGACGTAATCGTGCAGGCCGTGATCAAAGCCGTCACCGATTTCGCCGCCGGTGCGCCGCAGGCCG
ACGACATTACCCTACTGATCGCGAAGCGCCTCTAA

Upstream 100 bases:

>100_bases
AGCGCGAACCGCGACCGTCAGGGAGCGATCTAACAGTTCTTGCACCCCATCGCCGGGCACTGACCTATAATAGTGACTCA
CCGTCATTTAAGGACCGCTC

Downstream 100 bases:

>100_bases
GTGATTACCGACCTGGTCCAGATCAAACTGCTCGGCGAAAAGAAGCGCGACGAGAATCAGCGTTTTCGCAAGCACATGAA
AGCGCGCCATCACTCCGATC

Product: serine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSRELLIQCPDGQMKTVPLTGGRLSIGRSSAAELCFPEDAGLSRQHFAFEPEGEDWTVQDLGSKNGTFVNNIPLKARLIL
KPGDRVTAGHLVIVYSPDAVDPAAGVVVFEGETSSPTTSTVVTSLEGALSNQTMAIERGGPKASAPMQALIRAGLELSEN
RPLNELFPVILDLSIQAVNAQRGVLMILDGDQLIPRAHKGDGFRISTAVRDKVLKERSSILVRDAQLDDAFKGRMSIVEQ
KVHTMMAAPLQNKDRIIGLIYLDSPFILREFTKDDLNLLTVMANIAAARIENARLAEVEQAERIMARDLSQAGVIQSGML
PDKAPDVPGADLAGFNMACRTVGGDYYDFFKYPDGRVALALGDVSGKGMPASLIMMQLHARVQVLAEDPGNLAQFMTRIN
KATCAKCPSNRFITFFFSVLNAATGELAYANAGHNPPILVRANGDAEMLEGGGPVLGILPIAPYSEMHAHLDRGDMIAIY
SDGVTEANNVAYDEFDEERLIEVLKANRHEPADVIVQAVIKAVTDFAAGAPQADDITLLIAKRL

Sequences:

>Translated_544_residues
MSRELLIQCPDGQMKTVPLTGGRLSIGRSSAAELCFPEDAGLSRQHFAFEPEGEDWTVQDLGSKNGTFVNNIPLKARLIL
KPGDRVTAGHLVIVYSPDAVDPAAGVVVFEGETSSPTTSTVVTSLEGALSNQTMAIERGGPKASAPMQALIRAGLELSEN
RPLNELFPVILDLSIQAVNAQRGVLMILDGDQLIPRAHKGDGFRISTAVRDKVLKERSSILVRDAQLDDAFKGRMSIVEQ
KVHTMMAAPLQNKDRIIGLIYLDSPFILREFTKDDLNLLTVMANIAAARIENARLAEVEQAERIMARDLSQAGVIQSGML
PDKAPDVPGADLAGFNMACRTVGGDYYDFFKYPDGRVALALGDVSGKGMPASLIMMQLHARVQVLAEDPGNLAQFMTRIN
KATCAKCPSNRFITFFFSVLNAATGELAYANAGHNPPILVRANGDAEMLEGGGPVLGILPIAPYSEMHAHLDRGDMIAIY
SDGVTEANNVAYDEFDEERLIEVLKANRHEPADVIVQAVIKAVTDFAAGAPQADDITLLIAKRL
>Mature_543_residues
SRELLIQCPDGQMKTVPLTGGRLSIGRSSAAELCFPEDAGLSRQHFAFEPEGEDWTVQDLGSKNGTFVNNIPLKARLILK
PGDRVTAGHLVIVYSPDAVDPAAGVVVFEGETSSPTTSTVVTSLEGALSNQTMAIERGGPKASAPMQALIRAGLELSENR
PLNELFPVILDLSIQAVNAQRGVLMILDGDQLIPRAHKGDGFRISTAVRDKVLKERSSILVRDAQLDDAFKGRMSIVEQK
VHTMMAAPLQNKDRIIGLIYLDSPFILREFTKDDLNLLTVMANIAAARIENARLAEVEQAERIMARDLSQAGVIQSGMLP
DKAPDVPGADLAGFNMACRTVGGDYYDFFKYPDGRVALALGDVSGKGMPASLIMMQLHARVQVLAEDPGNLAQFMTRINK
ATCAKCPSNRFITFFFSVLNAATGELAYANAGHNPPILVRANGDAEMLEGGGPVLGILPIAPYSEMHAHLDRGDMIAIYS
DGVTEANNVAYDEFDEERLIEVLKANRHEPADVIVQAVIKAVTDFAAGAPQADDITLLIAKRL

Specific function: Involved in cross-regulation of inorganic carbon and glucose metabolisms [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003660
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00672 HAMP; PF07228 SpoIIE [H]

EC number: NA

Molecular weight: Translated: 58671; Mature: 58540

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50006 FHA_DOMAIN ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRELLIQCPDGQMKTVPLTGGRLSIGRSSAAELCFPEDAGLSRQHFAFEPEGEDWTVQD
CCCCEEEECCCCCEEEEEECCCEEECCCCCCCCEECCCCCCCCCCCEEECCCCCCEEHHC
LGSKNGTFVNNIPLKARLILKPGDRVTAGHLVIVYSPDAVDPAAGVVVFEGETSSPTTST
CCCCCCCEEECCCEEEEEEECCCCCEEECEEEEEECCCCCCCCCCEEEECCCCCCCCHHH
VVTSLEGALSNQTMAIERGGPKASAPMQALIRAGLELSENRPLNELFPVILDLSIQAVNA
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCEEEEEEC
QRGVLMILDGDQLIPRAHKGDGFRISTAVRDKVLKERSSILVRDAQLDDAFKGRMSIVEQ
CCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
KVHTMMAAPLQNKDRIIGLIYLDSPFILREFTKDDLNLLTVMANIAAARIENARLAEVEQ
HHHHHHHCCCCCCCCEEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
AERIMARDLSQAGVIQSGMLPDKAPDVPGADLAGFNMACRTVGGDYYDFFKYPDGRVALA
HHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHCCCCCEEEEE
LGDVSGKGMPASLIMMQLHARVQVLAEDPGNLAQFMTRINKATCAKCPSNRFITFFFSVL
EECCCCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
NAATGELAYANAGHNPPILVRANGDAEMLEGGGPVLGILPIAPYSEMHAHLDRGDMIAIY
HCCCCCEEEECCCCCCCEEEEECCCHHHHCCCCCEEEEEECCCHHHHHHHCCCCCEEEEE
SDGVTEANNVAYDEFDEERLIEVLKANRHEPADVIVQAVIKAVTDFAAGAPQADDITLLI
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
AKRL
EECC
>Mature Secondary Structure 
SRELLIQCPDGQMKTVPLTGGRLSIGRSSAAELCFPEDAGLSRQHFAFEPEGEDWTVQD
CCCEEEECCCCCEEEEEECCCEEECCCCCCCCEECCCCCCCCCCCEEECCCCCCEEHHC
LGSKNGTFVNNIPLKARLILKPGDRVTAGHLVIVYSPDAVDPAAGVVVFEGETSSPTTST
CCCCCCCEEECCCEEEEEEECCCCCEEECEEEEEECCCCCCCCCCEEEECCCCCCCCHHH
VVTSLEGALSNQTMAIERGGPKASAPMQALIRAGLELSENRPLNELFPVILDLSIQAVNA
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCEEEEEEC
QRGVLMILDGDQLIPRAHKGDGFRISTAVRDKVLKERSSILVRDAQLDDAFKGRMSIVEQ
CCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
KVHTMMAAPLQNKDRIIGLIYLDSPFILREFTKDDLNLLTVMANIAAARIENARLAEVEQ
HHHHHHHCCCCCCCCEEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
AERIMARDLSQAGVIQSGMLPDKAPDVPGADLAGFNMACRTVGGDYYDFFKYPDGRVALA
HHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHCCCCCEEEEE
LGDVSGKGMPASLIMMQLHARVQVLAEDPGNLAQFMTRINKATCAKCPSNRFITFFFSVL
EECCCCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
NAATGELAYANAGHNPPILVRANGDAEMLEGGGPVLGILPIAPYSEMHAHLDRGDMIAIY
HCCCCCEEEECCCCCCCEEEEECCCHHHHCCCCCEEEEEECCCHHHHHHHCCCCCEEEEE
SDGVTEANNVAYDEFDEERLIEVLKANRHEPADVIVQAVIKAVTDFAAGAPQADDITLLI
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
AKRL
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8075401; 8905231 [H]