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The map label for this gene is trpD

Identifier: 116622481

GI number: 116622481

Start: 4280024

End: 4281046

Strand: Direct

Name: trpD

Synonym: Acid_3379

Alternate gene names: 116622481

Gene position: 4280024-4281046 (Clockwise)

Preceding gene: 116622473

Following gene: 116622482

Centisome position: 42.95

GC content: 65.88

Gene sequence:

>1023_bases
ATGTCGCTTCTTCCACACTTGATGCGCCTCGTTGAGGAGCAGCATCTTTCTGCTGCCGACGCCGAGGCCGCCATGCAGAT
CGTTTTGCGCGGCGAGGCCAGCCACGCGCAAATCGCCGCTTTCCTGATCGCCCTTAAAATGAAGGGTGAGACCGTTGATG
AACTGGTCGGCTTCGCACGCGCTATGCGCGCCATGGCGGTCCCGGTCAGCCCCAATCTCGAAGGCGCCACACTGCTCGAT
ACCTGCGGCACCGGGGGCGATGGCGCCGGCACATTTAACATCTCCACCGTCGCCGCCTTCGTGGTGGCCGCCGCCGGCGT
CCACGTCGCCAAGCACGGCAATCGATCGATCACGAGCAAGTGCGGCAGCGCCGATCTTCTGGAGGCTTGGGGAATTCCGG
TCGCGATGCCGCCCGAGGCCACGGCGTTCGCCATCCGAGAAGTCGGCATCGGTTTCCTGTTCGCTCCCGCGGTCCATACA
GCGATGAAGCACGCTCATCCGGTGCGGGTCGATCTCAAACTGCGGACGGTCTTCAACCTCCTCGGTCCGCTCACCAATCC
CGCCGGCGCCACCGCGCAATTGATCGGCGCCCCGTCATCCCACGCCGCCGAACTGATGGCCGGCGCCATCGCGGCCCTCG
GTCTGGAGCGAGGCTTCGTGGTCCACGGCTCCGACGGCTTGGATGAGATCACCACTACCGGCCCCACACTCGCTTTTGAA
GTTCGCAATGGAAAGGTCGAGCGGCGCACGCTCGAGCCCGCGGACTTCGCCGTCGCCATCGCCGCGCCCGAAGATCTCAA
AGGCGGCGATCTGGCCCGCAATCTCGAAATCGCAGACTCCGTCCTGGCAGGCGCCGCCGGCCCCCACCGCGACATCGTCC
TGGTTAACGCCGCCGCCGCGCTGGTCGCCGCCGGGAAGGCCGACACCTTCCTTGAGGGTATGGCTCTCGGTGTGGTCGCG
ATCGATTCCGGCGCCGCCCGCGCGAAAGTAAAGGCCCTCGCCGATTTCGCAGCCAGTAGGTAG

Upstream 100 bases:

>100_bases
TGGCACAGGGACTTTGTATTGGGCCAGAATGGCCTTGGCTTGATACTCGTGAATTTTCATGGAGTTGCTGTGTTAGCCTA
CAGAAAACCCAATATACTAC

Downstream 100 bases:

>100_bases
CGTCGGTCGCATGAGAGAATGCCATGATGAAACGCCCATTCCCTGCGACCGTTTGGCGCGAAGGTAATTGGTATGTTGCC
TAGTGTCTGGAGATTGACAT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSLLPHLMRLVEEQHLSAADAEAAMQIVLRGEASHAQIAAFLIALKMKGETVDELVGFARAMRAMAVPVSPNLEGATLLD
TCGTGGDGAGTFNISTVAAFVVAAAGVHVAKHGNRSITSKCGSADLLEAWGIPVAMPPEATAFAIREVGIGFLFAPAVHT
AMKHAHPVRVDLKLRTVFNLLGPLTNPAGATAQLIGAPSSHAAELMAGAIAALGLERGFVVHGSDGLDEITTTGPTLAFE
VRNGKVERRTLEPADFAVAIAAPEDLKGGDLARNLEIADSVLAGAAGPHRDIVLVNAAAALVAAGKADTFLEGMALGVVA
IDSGAARAKVKALADFAASR

Sequences:

>Translated_340_residues
MSLLPHLMRLVEEQHLSAADAEAAMQIVLRGEASHAQIAAFLIALKMKGETVDELVGFARAMRAMAVPVSPNLEGATLLD
TCGTGGDGAGTFNISTVAAFVVAAAGVHVAKHGNRSITSKCGSADLLEAWGIPVAMPPEATAFAIREVGIGFLFAPAVHT
AMKHAHPVRVDLKLRTVFNLLGPLTNPAGATAQLIGAPSSHAAELMAGAIAALGLERGFVVHGSDGLDEITTTGPTLAFE
VRNGKVERRTLEPADFAVAIAAPEDLKGGDLARNLEIADSVLAGAAGPHRDIVLVNAAAALVAAGKADTFLEGMALGVVA
IDSGAARAKVKALADFAASR
>Mature_339_residues
SLLPHLMRLVEEQHLSAADAEAAMQIVLRGEASHAQIAAFLIALKMKGETVDELVGFARAMRAMAVPVSPNLEGATLLDT
CGTGGDGAGTFNISTVAAFVVAAAGVHVAKHGNRSITSKCGSADLLEAWGIPVAMPPEATAFAIREVGIGFLFAPAVHTA
MKHAHPVRVDLKLRTVFNLLGPLTNPAGATAQLIGAPSSHAAELMAGAIAALGLERGFVVHGSDGLDEITTTGPTLAFEV
RNGKVERRTLEPADFAVAIAAPEDLKGGDLARNLEIADSVLAGAAGPHRDIVLVNAAAALVAAGKADTFLEGMALGVVAI
DSGAARAKVKALADFAASR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=42.2535211267606, Blast_Score=192, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320561, Length=281, Percent_Identity=30.6049822064057, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_SOLUE (Q021N5)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_824637.1
- ProteinModelPortal:   Q021N5
- SMR:   Q021N5
- STRING:   Q021N5
- GeneID:   4428384
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_3379
- NMPDR:   fig|234267.9.peg.3205
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   ERTHEES
- PhylomeDB:   Q021N5
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34702; Mature: 34571

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPHLMRLVEEQHLSAADAEAAMQIVLRGEASHAQIAAFLIALKMKGETVDELVGFAR
CCHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AMRAMAVPVSPNLEGATLLDTCGTGGDGAGTFNISTVAAFVVAAAGVHVAKHGNRSITSK
HHHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHCHHEECCCCCHHHHC
CGSADLLEAWGIPVAMPPEATAFAIREVGIGFLFAPAVHTAMKHAHPVRVDLKLRTVFNL
CCCCHHHHHCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
LGPLTNPAGATAQLIGAPSSHAAELMAGAIAALGLERGFVVHGSDGLDEITTTGPTLAFE
HCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCEEEEE
VRNGKVERRTLEPADFAVAIAAPEDLKGGDLARNLEIADSVLAGAAGPHRDIVLVNAAAA
ECCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHH
LVAAGKADTFLEGMALGVVAIDSGAARAKVKALADFAASR
HHHCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLLPHLMRLVEEQHLSAADAEAAMQIVLRGEASHAQIAAFLIALKMKGETVDELVGFAR
CHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AMRAMAVPVSPNLEGATLLDTCGTGGDGAGTFNISTVAAFVVAAAGVHVAKHGNRSITSK
HHHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHCHHEECCCCCHHHHC
CGSADLLEAWGIPVAMPPEATAFAIREVGIGFLFAPAVHTAMKHAHPVRVDLKLRTVFNL
CCCCHHHHHCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
LGPLTNPAGATAQLIGAPSSHAAELMAGAIAALGLERGFVVHGSDGLDEITTTGPTLAFE
HCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCEEEEE
VRNGKVERRTLEPADFAVAIAAPEDLKGGDLARNLEIADSVLAGAAGPHRDIVLVNAAAA
ECCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHH
LVAAGKADTFLEGMALGVVAIDSGAARAKVKALADFAASR
HHHCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA