Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 116622473

GI number: 116622473

Start: 4272750

End: 4274195

Strand: Direct

Name: degP [H]

Synonym: Acid_3371

Alternate gene names: 116622473

Gene position: 4272750-4274195 (Clockwise)

Preceding gene: 116622472

Following gene: 116622481

Centisome position: 42.87

GC content: 63.9

Gene sequence:

>1446_bases
ATGGTTCGAACCTGCCTGGTAATTGTTGCCTGTTTTTTCCTCGCCTCGTGCCACAGCCCGCAGGCGGTCAGTGCGAACAA
CGAAAAACGCCAGCTACCCGCGGCAAATACGGGCGAGAATCTTCCGATTCTCTCCTACTCCCCGGTGGTGGACCACGTGG
CGCCCGCCGTTGTCACCATCCGTGCCTCGCACCGCGTGCGCGCCCCGCGGCAGTTCCCTTTCTCCGACACCCCGCTCTTC
CGCGAGTTCTTCGGCGGCGGATCGCCCGTCCCGCGCGATCGCCCGGAAGTGGAGTCGGCGCTCGGCTCCGGTGTCATCGT
CCGGTCCGATGGACATATCCTCACCAACCACCACGTGATCGATGGCGCGGAAGATATCAAGGTTGATCTCAGTACCCGCC
GCACTTACTCCGCCAAGGTCGTCGGCAGCGATTCTCCTAGTGACATCGCGGTACTCAAGATCAGCGGAGGAGACCTTCCG
GTCCTCCAGCTTGGCGATTCGGACCGTGTGCGCGTGGGGGACGTCTGTCTCGCCGTCGGCAATCCTTTGGCGGTCGGTGA
ATCCGTCACCGCCGGTATCATCAGCGCCAAGGGACGCTCCACCGACAGTGTCGGCGGCGGCAGCTTTCAGGATTTCCTCC
AGACGGATGCGCCCATTAACCAGGGCAACTCCGGAGGAGCGCTGGTCAATACCCGCGGCGAACTGATCGGGATCAATTCG
CAGATCCTCTCCTCTAACGGCGGCAATGTCGGCATCGGCTTCGCGATTCCTTCCAACATGGCCAAGAGCGTGATGGATCA
GTTGATCGGGAAGGGAAGCGTGCAGCGAGGTATGCTCGGCGTTAGCATCCAGCCTGTCACCAGCGACATCGCTTCCAGCC
TCGGCCTGAAGGATGTGCGCGGCATCCTCATCAATTCCGTGACTCCCGCCGGCCCGGCCGAAAAAGCCGGTCTCCAGCGC
GGTGACGTGATTCTGCAGGTCGATGGCAAGGACGTGAACGAGCCCAACCAGCTGCGCAATGAGATCGCCGCGCGCGCCCC
GGGTGCGGAGATCAACCTCACCATTCAGCGCGACGGGAAACAACAGCAGGTCCGCACCAAACTGGGCACTCTCACTCCGC
AGACTGCCGCCGCGGACGCGCCGGGAGGCGGATCGGGTGGAGGCGGCAAACTGGGTATTGGCGTAGTGCCCCTCACTCCC
GACCTTGCCGCGCAGCTTGGCCTGCGCCGCGGAGCGCAGGGGCTGGCCGTCCAGTCGATCGACCCCGAAGGTCCCGCCGC
ACAGGCCGGCCTGCGCGAAGGCGACGTCATTCAGGAGGTGAACCGCCAGCCCGTCCACACCATCGACGAGCTGCGCAGCG
CCCTCCAGAAATCCGGCGACCGCGCACCCTTACTGCTGATTAACCGCGAAGGTCAATCCGCCTACGTGCCAGTGCCATTG
AAGTGA

Upstream 100 bases:

>100_bases
CGAAATTAAGCCGTAACGCGGAGCACTTAGTGCCGCGGTTCTCGGCACGGTTGGAGACAGTAGGTCTCCAACCCGGAGAG
TCACGTGCTACCGGAAAGGC

Downstream 100 bases:

>100_bases
GACAGGCATCCCGGCCTGTCTTCCAATTGAATCCGGAACTCATGTGCCGGCAATCCGCCTTCGATCGCTTCCAGCGCCCG
TGTCGCATCGCCGTGCAAGC

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVRTCLVIVACFFLASCHSPQAVSANNEKRQLPAANTGENLPILSYSPVVDHVAPAVVTIRASHRVRAPRQFPFSDTPLF
REFFGGGSPVPRDRPEVESALGSGVIVRSDGHILTNHHVIDGAEDIKVDLSTRRTYSAKVVGSDSPSDIAVLKISGGDLP
VLQLGDSDRVRVGDVCLAVGNPLAVGESVTAGIISAKGRSTDSVGGGSFQDFLQTDAPINQGNSGGALVNTRGELIGINS
QILSSNGGNVGIGFAIPSNMAKSVMDQLIGKGSVQRGMLGVSIQPVTSDIASSLGLKDVRGILINSVTPAGPAEKAGLQR
GDVILQVDGKDVNEPNQLRNEIAARAPGAEINLTIQRDGKQQQVRTKLGTLTPQTAAADAPGGGSGGGGKLGIGVVPLTP
DLAAQLGLRRGAQGLAVQSIDPEGPAAQAGLREGDVIQEVNRQPVHTIDELRSALQKSGDRAPLLLINREGQSAYVPVPL
K

Sequences:

>Translated_481_residues
MVRTCLVIVACFFLASCHSPQAVSANNEKRQLPAANTGENLPILSYSPVVDHVAPAVVTIRASHRVRAPRQFPFSDTPLF
REFFGGGSPVPRDRPEVESALGSGVIVRSDGHILTNHHVIDGAEDIKVDLSTRRTYSAKVVGSDSPSDIAVLKISGGDLP
VLQLGDSDRVRVGDVCLAVGNPLAVGESVTAGIISAKGRSTDSVGGGSFQDFLQTDAPINQGNSGGALVNTRGELIGINS
QILSSNGGNVGIGFAIPSNMAKSVMDQLIGKGSVQRGMLGVSIQPVTSDIASSLGLKDVRGILINSVTPAGPAEKAGLQR
GDVILQVDGKDVNEPNQLRNEIAARAPGAEINLTIQRDGKQQQVRTKLGTLTPQTAAADAPGGGSGGGGKLGIGVVPLTP
DLAAQLGLRRGAQGLAVQSIDPEGPAAQAGLREGDVIQEVNRQPVHTIDELRSALQKSGDRAPLLLINREGQSAYVPVPL
K
>Mature_481_residues
MVRTCLVIVACFFLASCHSPQAVSANNEKRQLPAANTGENLPILSYSPVVDHVAPAVVTIRASHRVRAPRQFPFSDTPLF
REFFGGGSPVPRDRPEVESALGSGVIVRSDGHILTNHHVIDGAEDIKVDLSTRRTYSAKVVGSDSPSDIAVLKISGGDLP
VLQLGDSDRVRVGDVCLAVGNPLAVGESVTAGIISAKGRSTDSVGGGSFQDFLQTDAPINQGNSGGALVNTRGELIGINS
QILSSNGGNVGIGFAIPSNMAKSVMDQLIGKGSVQRGMLGVSIQPVTSDIASSLGLKDVRGILINSVTPAGPAEKAGLQR
GDVILQVDGKDVNEPNQLRNEIAARAPGAEINLTIQRDGKQQQVRTKLGTLTPQTAAADAPGGGSGGGGKLGIGVVPLTP
DLAAQLGLRRGAQGLAVQSIDPEGPAAQAGLREGDVIQEVNRQPVHTIDELRSALQKSGDRAPLLLINREGQSAYVPVPL
K

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=322, Percent_Identity=36.0248447204969, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI22129776, Length=315, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI24308541, Length=298, Percent_Identity=34.8993288590604, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI7019477, Length=327, Percent_Identity=33.6391437308869, Blast_Score=131, Evalue=2e-30,
Organism=Escherichia coli, GI1789629, Length=421, Percent_Identity=41.3301662707838, Blast_Score=281, Evalue=9e-77,
Organism=Escherichia coli, GI1786356, Length=470, Percent_Identity=38.0851063829787, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1789630, Length=273, Percent_Identity=44.3223443223443, Blast_Score=197, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24646839, Length=293, Percent_Identity=34.4709897610922, Blast_Score=141, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49802; Mature: 49802

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTCLVIVACFFLASCHSPQAVSANNEKRQLPAANTGENLPILSYSPVVDHVAPAVVTI
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCEEECCCHHHHHCCEEEEE
RASHRVRAPRQFPFSDTPLFREFFGGGSPVPRDRPEVESALGSGVIVRSDGHILTNHHVI
ECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCCEEEECCCEEEECCEEE
DGAEDIKVDLSTRRTYSAKVVGSDSPSDIAVLKISGGDLPVLQLGDSDRVRVGDVCLAVG
CCCCCEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCEEECEEEEECC
NPLAVGESVTAGIISAKGRSTDSVGGGSFQDFLQTDAPINQGNSGGALVNTRGELIGINS
CCCCCCCCHHHHEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCEEECCH
QILSSNGGNVGIGFAIPSNMAKSVMDQLIGKGSVQRGMLGVSIQPVTSDIASSLGLKDVR
HHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHCCEEEEEECHHHHHHHHHCCHHHHH
GILINSVTPAGPAEKAGLQRGDVILQVDGKDVNEPNQLRNEIAARAPGAEINLTIQRDGK
HHHEECCCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCC
QQQVRTKLGTLTPQTAAADAPGGGSGGGGKLGIGVVPLTPDLAAQLGLRRGAQGLAVQSI
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCEEEEC
DPEGPAAQAGLREGDVIQEVNRQPVHTIDELRSALQKSGDRAPLLLINREGQSAYVPVPL
CCCCCHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCC
K
C
>Mature Secondary Structure
MVRTCLVIVACFFLASCHSPQAVSANNEKRQLPAANTGENLPILSYSPVVDHVAPAVVTI
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCEEECCCHHHHHCCEEEEE
RASHRVRAPRQFPFSDTPLFREFFGGGSPVPRDRPEVESALGSGVIVRSDGHILTNHHVI
ECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCCEEEECCCEEEECCEEE
DGAEDIKVDLSTRRTYSAKVVGSDSPSDIAVLKISGGDLPVLQLGDSDRVRVGDVCLAVG
CCCCCEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCEEECEEEEECC
NPLAVGESVTAGIISAKGRSTDSVGGGSFQDFLQTDAPINQGNSGGALVNTRGELIGINS
CCCCCCCCHHHHEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCEEECCH
QILSSNGGNVGIGFAIPSNMAKSVMDQLIGKGSVQRGMLGVSIQPVTSDIASSLGLKDVR
HHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHCCEEEEEECHHHHHHHHHCCHHHHH
GILINSVTPAGPAEKAGLQRGDVILQVDGKDVNEPNQLRNEIAARAPGAEINLTIQRDGK
HHHEECCCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCC
QQQVRTKLGTLTPQTAAADAPGGGSGGGGKLGIGVVPLTPDLAAQLGLRRGAQGLAVQSI
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCEEEEC
DPEGPAAQAGLREGDVIQEVNRQPVHTIDELRSALQKSGDRAPLLLINREGQSAYVPVPL
CCCCCHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]