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The map label for this gene is atoS [C]

Identifier: 116622423

GI number: 116622423

Start: 4200294

End: 4202366

Strand: Direct

Name: atoS [C]

Synonym: Acid_3320

Alternate gene names: 116622423

Gene position: 4200294-4202366 (Clockwise)

Preceding gene: 116622422

Following gene: 116622426

Centisome position: 42.15

GC content: 63.24

Gene sequence:

>2073_bases
ATGCCCGAACCACGTGAAGAACTAGAATCTCAGCGCGTCCGTGAACTGGAAGAGCTGCTCACGCGGGAGATCGGCGCGCG
CAAGCGGGCTGAGGAGGCGCTGAGCCAAAGCGAGGCGCGCTTCCGCTTTATTGTCAAGGGTTTCAGCGAAATGGTGCTGG
CCTATGACATGGACCGGCGCTTGACCTTCGTTAATGCGGCGGCGCAATCCCTGACCGGATATTCGGCCGCGGAATTGCAG
CAGGAAGGCTTTATCTGCTGGGTCCACCCCGACGACCGTGGGCGCATGCTTGGGTACTGGGACCGCTTGTTCACCGGCCT
GAGTTTCCAGGAGGAAGAATACCGGCTGGTCACGCGCGACGGGCGGGTGAAATGGATGTCGGCCTCCTGGGGCCCGCTTA
TGGATGACAACGGCCGCCAGGTGGGCGTGCAGGGGCGCGAGCGCGAAGTTACCGAGCGCCGCATGGCGGAAGAGACCCTG
CGGATTCGCGAACAGCGCTATCGCACCCTGTTCGAGGAATCGCCCTTCCCCATGTGGGAGGAGGACTTCTCGGAGGTGAA
GCGCTTCCTGGACGCATTGCGGGCACGCGGCATTCGGGAAGTGGGATCGCACCTGATGCAGAATCGGGAGGATCTGGCGG
AATGTGTGAGGCGCATCCGGATCCTGGACGTGAATCACGCCGCCCGTCAGTTCTACGGCGTCTCGACCAAGGACGAGTTG
ATGGGGGACCTTAGCCGGATCCTGGATGAAGAGGGTTGGGATGTGATCTGCGCGGAGATGGCCAGCCTGGCGGACGGCGC
CTCAATGTTCAAGGCCGAGTTCGAGACGCGAACGATCCTCGGGGAGCAGCGAACCGTCAGCATGATCGTATCGCTGGAGC
CTTCGCCGGGCGATTGGTCAAGGGTGATCGTCTCCTTCTTCGACATCACCGACCGCAAACGGCTGGAGGAGCAGTTCCTG
CAATCGCAGAAGCTGGAGAGCCTGGGCCGCCTCGCGGGCGGCATCGCGCACGATTTCAACAACCTGCTGATGGTGATCAC
GGGTTATAGCGAACTGTTGCTGTCCGACGCGGGCCTCAGCCAGCGGACGATGACGGGCCTGCGTGAGATCCGCTGCGCGG
GCGATCGCGGAGCGGAGTTGACCGGACAACTGCTGGCCTTCAGCCGCAAACAGATCGGCCATCCGCGCGCGCTGGACCTG
AACGCACTGGTGCGTGAATCGCAAGGCATGCTGGAGCGGTTATTGGGCGAGGATGTGCGGCTGGCGGTGTCGCTGGATCC
GGCGGCCTCCGCCATCCGCGCCGATCGCGGCCAGATGCACCAGGTACTGATGAACCTGGTGGTGAACGCCCGCGAGGCGA
TGCCGGAAGGTGGAACGCTGTGGATCGAGACGGCCAATGTGACCGAGGGCGGATTAGGCTACGTGCGGCTCCGGGTGGCC
GATACCGGGGTAGGAATGGATGAGCGCACGCGGCTGCTGGTGTTCGAACCGTTCTTCACGACGAAAGGCGCCTCCAAAGG
TACAGGCTTGGGCCTGGCGACCGTGTTTGGCGTGGTGACTCAGGCCGGGGGACATATTTCGGTGACGAGCGAGCCGGGGC
ATGGCGCGGTGTTCAACCTCTATTTGCCGGGAGTCGCCTTACCGTCGAATGGAGACGCCGCACTGGAGACGAAAGTGAAG
ACCTCCGCTGGATGGGGTACGCTGCTGGTGGTGGAGGACCAGGAGGACGTGCGGCGTCTCGCCGTCCTGATCCTCGAAGG
TCTGGGCTACACGGTTTTGGAGGCCGCCAACGGCAATGAGGCGCTGGACGTCGCGCGGGAACACCAGGGCTGCATCCGCC
TGATGCTGACCGACGTGATCATGCCGGGCATGAACGGCCGCGAACTTGCCGAACAGATGACGGCGATCCGCCCCGAGATG
AAGGTGGTCTTCATGTCCGGTTATACGGACCGCATCATGAGTCCGGACGGGGTGCTCGACAGTTCCGTGCACTACCTGCA
AAAGCCCTTCGCGGCGGAGCAGCTAAACGCCAAGATCCGCGAGGTCCTCGACTCCGGCGAAAGCGTGCCTTAA

Upstream 100 bases:

>100_bases
ACCTGGCGCTAAGCCTCTGGGCCAGGAAAGCGGACGCCGGAATCCTCAAGCGATAACCCGGGTGCGCGTGGGACCAGTAT
GATGGTCATAGCAGCGCCTC

Downstream 100 bases:

>100_bases
CACCCCTTTGGGCCGGATGTGGCGAAATAGGACAGCTGGCTCTGAAAGATCTCTGGAAAAACGCGCAGTTTAGGACTACA
ATCTACCCAAGACGGAACCC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPEPREELESQRVRELEELLTREIGARKRAEEALSQSEARFRFIVKGFSEMVLAYDMDRRLTFVNAAAQSLTGYSAAELQ
QEGFICWVHPDDRGRMLGYWDRLFTGLSFQEEEYRLVTRDGRVKWMSASWGPLMDDNGRQVGVQGREREVTERRMAEETL
RIREQRYRTLFEESPFPMWEEDFSEVKRFLDALRARGIREVGSHLMQNREDLAECVRRIRILDVNHAARQFYGVSTKDEL
MGDLSRILDEEGWDVICAEMASLADGASMFKAEFETRTILGEQRTVSMIVSLEPSPGDWSRVIVSFFDITDRKRLEEQFL
QSQKLESLGRLAGGIAHDFNNLLMVITGYSELLLSDAGLSQRTMTGLREIRCAGDRGAELTGQLLAFSRKQIGHPRALDL
NALVRESQGMLERLLGEDVRLAVSLDPAASAIRADRGQMHQVLMNLVVNAREAMPEGGTLWIETANVTEGGLGYVRLRVA
DTGVGMDERTRLLVFEPFFTTKGASKGTGLGLATVFGVVTQAGGHISVTSEPGHGAVFNLYLPGVALPSNGDAALETKVK
TSAGWGTLLVVEDQEDVRRLAVLILEGLGYTVLEAANGNEALDVAREHQGCIRLMLTDVIMPGMNGRELAEQMTAIRPEM
KVVFMSGYTDRIMSPDGVLDSSVHYLQKPFAAEQLNAKIREVLDSGESVP

Sequences:

>Translated_690_residues
MPEPREELESQRVRELEELLTREIGARKRAEEALSQSEARFRFIVKGFSEMVLAYDMDRRLTFVNAAAQSLTGYSAAELQ
QEGFICWVHPDDRGRMLGYWDRLFTGLSFQEEEYRLVTRDGRVKWMSASWGPLMDDNGRQVGVQGREREVTERRMAEETL
RIREQRYRTLFEESPFPMWEEDFSEVKRFLDALRARGIREVGSHLMQNREDLAECVRRIRILDVNHAARQFYGVSTKDEL
MGDLSRILDEEGWDVICAEMASLADGASMFKAEFETRTILGEQRTVSMIVSLEPSPGDWSRVIVSFFDITDRKRLEEQFL
QSQKLESLGRLAGGIAHDFNNLLMVITGYSELLLSDAGLSQRTMTGLREIRCAGDRGAELTGQLLAFSRKQIGHPRALDL
NALVRESQGMLERLLGEDVRLAVSLDPAASAIRADRGQMHQVLMNLVVNAREAMPEGGTLWIETANVTEGGLGYVRLRVA
DTGVGMDERTRLLVFEPFFTTKGASKGTGLGLATVFGVVTQAGGHISVTSEPGHGAVFNLYLPGVALPSNGDAALETKVK
TSAGWGTLLVVEDQEDVRRLAVLILEGLGYTVLEAANGNEALDVAREHQGCIRLMLTDVIMPGMNGRELAEQMTAIRPEM
KVVFMSGYTDRIMSPDGVLDSSVHYLQKPFAAEQLNAKIREVLDSGESVP
>Mature_689_residues
PEPREELESQRVRELEELLTREIGARKRAEEALSQSEARFRFIVKGFSEMVLAYDMDRRLTFVNAAAQSLTGYSAAELQQ
EGFICWVHPDDRGRMLGYWDRLFTGLSFQEEEYRLVTRDGRVKWMSASWGPLMDDNGRQVGVQGREREVTERRMAEETLR
IREQRYRTLFEESPFPMWEEDFSEVKRFLDALRARGIREVGSHLMQNREDLAECVRRIRILDVNHAARQFYGVSTKDELM
GDLSRILDEEGWDVICAEMASLADGASMFKAEFETRTILGEQRTVSMIVSLEPSPGDWSRVIVSFFDITDRKRLEEQFLQ
SQKLESLGRLAGGIAHDFNNLLMVITGYSELLLSDAGLSQRTMTGLREIRCAGDRGAELTGQLLAFSRKQIGHPRALDLN
ALVRESQGMLERLLGEDVRLAVSLDPAASAIRADRGQMHQVLMNLVVNAREAMPEGGTLWIETANVTEGGLGYVRLRVAD
TGVGMDERTRLLVFEPFFTTKGASKGTGLGLATVFGVVTQAGGHISVTSEPGHGAVFNLYLPGVALPSNGDAALETKVKT
SAGWGTLLVVEDQEDVRRLAVLILEGLGYTVLEAANGNEALDVAREHQGCIRLMLTDVIMPGMNGRELAEQMTAIRPEMK
VVFMSGYTDRIMSPDGVLDSSVHYLQKPFAAEQLNAKIREVLDSGESVP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=270, Percent_Identity=33.7037037037037, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=31.7073170731707, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI87081816, Length=329, Percent_Identity=26.7477203647416, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=392, Percent_Identity=24.234693877551, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=347, Percent_Identity=24.7838616714697, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=334, Percent_Identity=27.5449101796407, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=26.2962962962963, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77114; Mature: 76983

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEPREELESQRVRELEELLTREIGARKRAEEALSQSEARFRFIVKGFSEMVLAYDMDRR
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LTFVNAAAQSLTGYSAAELQQEGFICWVHPDDRGRMLGYWDRLFTGLSFQEEEYRLVTRD
HHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEC
GRVKWMSASWGPLMDDNGRQVGVQGREREVTERRMAEETLRIREQRYRTLFEESPFPMWE
CCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EDFSEVKRFLDALRARGIREVGSHLMQNREDLAECVRRIRILDVNHAARQFYGVSTKDEL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHEEECCCHHHHHHCCCCCHHHH
MGDLSRILDEEGWDVICAEMASLADGASMFKAEFETRTILGEQRTVSMIVSLEPSPGDWS
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHH
RVIVSFFDITDRKRLEEQFLQSQKLESLGRLAGGIAHDFNNLLMVITGYSELLLSDAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCC
QRTMTGLREIRCAGDRGAELTGQLLAFSRKQIGHPRALDLNALVRESQGMLERLLGEDVR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
LAVSLDPAASAIRADRGQMHQVLMNLVVNAREAMPEGGTLWIETANVTEGGLGYVRLRVA
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEE
DTGVGMDERTRLLVFEPFFTTKGASKGTGLGLATVFGVVTQAGGHISVTSEPGHGAVFNL
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEE
YLPGVALPSNGDAALETKVKTSAGWGTLLVVEDQEDVRRLAVLILEGLGYTVLEAANGNE
EECCEECCCCCCCEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCH
ALDVAREHQGCIRLMLTDVIMPGMNGRELAEQMTAIRPEMKVVFMSGYTDRIMSPDGVLD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCH
SSVHYLQKPFAAEQLNAKIREVLDSGESVP
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PEPREELESQRVRELEELLTREIGARKRAEEALSQSEARFRFIVKGFSEMVLAYDMDRR
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LTFVNAAAQSLTGYSAAELQQEGFICWVHPDDRGRMLGYWDRLFTGLSFQEEEYRLVTRD
HHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEC
GRVKWMSASWGPLMDDNGRQVGVQGREREVTERRMAEETLRIREQRYRTLFEESPFPMWE
CCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EDFSEVKRFLDALRARGIREVGSHLMQNREDLAECVRRIRILDVNHAARQFYGVSTKDEL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHEEECCCHHHHHHCCCCCHHHH
MGDLSRILDEEGWDVICAEMASLADGASMFKAEFETRTILGEQRTVSMIVSLEPSPGDWS
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHH
RVIVSFFDITDRKRLEEQFLQSQKLESLGRLAGGIAHDFNNLLMVITGYSELLLSDAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCC
QRTMTGLREIRCAGDRGAELTGQLLAFSRKQIGHPRALDLNALVRESQGMLERLLGEDVR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
LAVSLDPAASAIRADRGQMHQVLMNLVVNAREAMPEGGTLWIETANVTEGGLGYVRLRVA
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEE
DTGVGMDERTRLLVFEPFFTTKGASKGTGLGLATVFGVVTQAGGHISVTSEPGHGAVFNL
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEE
YLPGVALPSNGDAALETKVKTSAGWGTLLVVEDQEDVRRLAVLILEGLGYTVLEAANGNE
EECCEECCCCCCCEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCH
ALDVAREHQGCIRLMLTDVIMPGMNGRELAEQMTAIRPEMKVVFMSGYTDRIMSPDGVLD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCH
SSVHYLQKPFAAEQLNAKIREVLDSGESVP
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA