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The map label for this gene is tdk [H]

Identifier: 116622304

GI number: 116622304

Start: 4045202

End: 4045819

Strand: Direct

Name: tdk [H]

Synonym: Acid_3198

Alternate gene names: 116622304

Gene position: 4045202-4045819 (Clockwise)

Preceding gene: 116622303

Following gene: 116622313

Centisome position: 40.59

GC content: 59.39

Gene sequence:

>618_bases
ATGGACATCATCACTGGCAACGTGGGCTGGATCGAAGTCATCTGCGGCCCCATGTTCTCGGGCAAAAGCGAGGAACTGAT
CCGGCGCCTGCGTCGCGCCATGATCGCCCGCAAACGCGTCGAGGTTTTCAAGCCGATCATCGATAACCGATACTCCGACG
ACGAGATCGTTTCTCACGGCGATTTGCGGATGAAATCCCAGGTGGTTAAGGATGCCGAAGAGATTACGCGACGCATTGAC
TGGCGCAGCGAGGTAGTGGGCATCGACGAAGCCAATTTCATGGGGCCGCAACTGGTGGACGTCGCCCAGCGGCTCGCCGA
CAGCGGCAAACAGGTGATCATCAGCGGCCTGGATACCGACTATCTAGGACGGCCCTTCGCACCCATTCCAGATCTTCTGG
CGCATGCCGAGTCGATCACCAAGACCCTGGCTATCTGCGTTCGCTGCGGCAATCCCGCCAAGCACACGCAGAGGCTACGC
GGGTCGGAAGACCTGATCGTGGTGGGTGCGTCGGACATGTACGAGGCGCGCTGCCGGCGATGTTTCGAGCCCGGCATACC
GAAGCAGACCGAGCTCGATTTCGTCAAAGCCAAACGTCAGGAAAAGCCTACCAGTTGA

Upstream 100 bases:

>100_bases
GCTCGTACCGCGCCCATAAGATAAAGGGCTCCTTATTCGGGTGCAAACCGCGGGCTAGTTTGGTTTTCTGCGGCGCAGTA
TGTCATCCTGATCAATTCCT

Downstream 100 bases:

>100_bases
AGCGCAGGCCCAGTTGCAGCAGGCGCTGATCGCGCGAGGCGTTGGGCGCCAAGGTTGCCGGAGTGGTGATGTTGCCCGCC
GTATCTACTGTCGCGGTCGA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MDIITGNVGWIEVICGPMFSGKSEELIRRLRRAMIARKRVEVFKPIIDNRYSDDEIVSHGDLRMKSQVVKDAEEITRRID
WRSEVVGIDEANFMGPQLVDVAQRLADSGKQVIISGLDTDYLGRPFAPIPDLLAHAESITKTLAICVRCGNPAKHTQRLR
GSEDLIVVGASDMYEARCRRCFEPGIPKQTELDFVKAKRQEKPTS

Sequences:

>Translated_205_residues
MDIITGNVGWIEVICGPMFSGKSEELIRRLRRAMIARKRVEVFKPIIDNRYSDDEIVSHGDLRMKSQVVKDAEEITRRID
WRSEVVGIDEANFMGPQLVDVAQRLADSGKQVIISGLDTDYLGRPFAPIPDLLAHAESITKTLAICVRCGNPAKHTQRLR
GSEDLIVVGASDMYEARCRRCFEPGIPKQTELDFVKAKRQEKPTS
>Mature_205_residues
MDIITGNVGWIEVICGPMFSGKSEELIRRLRRAMIARKRVEVFKPIIDNRYSDDEIVSHGDLRMKSQVVKDAEEITRRID
WRSEVVGIDEANFMGPQLVDVAQRLADSGKQVIISGLDTDYLGRPFAPIPDLLAHAESITKTLAICVRCGNPAKHTQRLR
GSEDLIVVGASDMYEARCRRCFEPGIPKQTELDFVKAKRQEKPTS

Specific function: Unknown

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=174, Percent_Identity=37.3563218390805, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17543396, Length=178, Percent_Identity=35.3932584269663, Blast_Score=109, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 23097; Mature: 23097

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIITGNVGWIEVICGPMFSGKSEELIRRLRRAMIARKRVEVFKPIIDNRYSDDEIVSHG
CCEECCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
DLRMKSQVVKDAEEITRRIDWRSEVVGIDEANFMGPQLVDVAQRLADSGKQVIISGLDTD
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCH
YLGRPFAPIPDLLAHAESITKTLAICVRCGNPAKHTQRLRGSEDLIVVGASDMYEARCRR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHH
CFEPGIPKQTELDFVKAKRQEKPTS
HHCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDIITGNVGWIEVICGPMFSGKSEELIRRLRRAMIARKRVEVFKPIIDNRYSDDEIVSHG
CCEECCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
DLRMKSQVVKDAEEITRRIDWRSEVVGIDEANFMGPQLVDVAQRLADSGKQVIISGLDTD
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCH
YLGRPFAPIPDLLAHAESITKTLAICVRCGNPAKHTQRLRGSEDLIVVGASDMYEARCRR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHH
CFEPGIPKQTELDFVKAKRQEKPTS
HHCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA