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The map label for this gene is 116621756

Identifier: 116621756

GI number: 116621756

Start: 3337839

End: 3339230

Strand: Direct

Name: 116621756

Synonym: Acid_2638

Alternate gene names: NA

Gene position: 3337839-3339230 (Clockwise)

Preceding gene: 116621755

Following gene: 116621760

Centisome position: 33.49

GC content: 63.07

Gene sequence:

>1392_bases
GTGAAAGCCCTGATCGCCATCCTCGGGCTCGCCTCCTTTATGGCCGGCGGCCAACAAGGCAGCGACGCGGAAGTCTGGCT
CACCACTCCGGACAAATCTGCGCTCTTCGAACGGCAGAAGCAGTCGCCCGTCCTAGCCGCCCCCGGCAGCAGGAATCCCA
CCATCGAGATCGACGAGCGGCAGAAGTTTCAGCCCATCGATGGCTTCGGCTTCGCCCTCACCGGCGGCAGCGCGCAGCAC
CTCGTCCGCATGAGCGCCGCCGCGCGCGCCGCCATTCTCAAAGAGCTGTTCGGCACCGCCGATCGCGAGATCGGCGTGAG
CTATCTGCGTCTCACCATCGGCGCGTCCGATTTGAACGACCACGTCTTCACGTACGACGACATGCCGGACGGCCAGACCG
ACCCCGACCTCCAGCACTTCGATCTCGGACCCGACAAAGCCGACGTCATCCCGGTGATGAAGGAGATCCTCAAGCTCAAT
CCGCGCATCAAAATCCTTGCCTCGCCGTGGACCGCGCCTTCGTGGATGAAGACCAACAACAACGCGAAGGGCGGCGCGCT
CAAGCCCGAAGCCTACCCCGCCTACGCGCAATACTTCGTCAAATATATCCGCGCCATGAAAGCCGAAGGCATCGCTATCG
ATGCCATCACGGTGCAGAACGAGCCGCTCAATCCCAAGAACACGCCTAGCCTCGTCATGCAGTCCGCCGAGGAAGCGCTC
TTCATCAAGAGCCATCTCGGTCCCGCATTTCACGCCGCGGGCATCAAGACCCATATCGTGCTCTACGACCACAATTGCGA
CGTCCCCGAATACGCCACCGCGATCCTCGCCGATCGCGCTGCGGCCCGCTACGTCGATGGCTCCGGTTTCCACCTCTACG
GCGGCAAGATAGAGGCCATGACCCAGGTTCACGACCAGTATCCGGTGAAGAATCTCTACTTCACGGAACAGATGGTGGTC
GGCTCGGTGGAGAGCAAGCCCGCCATCAACATCGCCGCGCCGGTGCGCCGCCTGATCATCGGCGCCACCCGCAACTGGAG
CCGGAACGTCGTGCTGTGGAACCTCGCCGCCGACCCGAAGAACAATCCGCACACCGACGATGGCGGCTGCGGTATGTGCC
AGGGCGCCATCACGATCGATGGCGACCAGGTAAGCCGCAACCTGGCATACTACGCCATCGCCCATGCCTCTAAATTCGTG
CGCCCTGGCGCCGTGCGGATCGCTTCCACCAGCCTGGAGTCGCTCCCCAACGTCGCCTTCCGGACTCCCTCCGGCAAGCG
CGTCCTGATCGTAGTCAACGCGAGTCAAACGTCGCAGACCTTCGATATCCAGGCCGCGAAACGAATGTCCGCGACCCTCC
CTCCCGGCGCCGTCGCAACGTATGTCTGGTAG

Upstream 100 bases:

>100_bases
TGCAATTGGTCTTCGGCGGCGCCGATGGCAAGACGTTGTTCGTCCCCGCGCGCACCTCGCTATACGCCGTGCGCACGAAA
TTCGCGGGCCGGAGGGCGCA

Downstream 100 bases:

>100_bases
GACGGGCCTCCTGGCCGGCCCCGCTAATCAGAGCTTCAGCCGCATCTCGTTCGTCGGCTTGAACCCAATCCCTTCGTAAA
GCGCGCGCCCGAGTGGACTG

Product: glucosylceramidase

Products: NA

Alternate protein names: Glucan Endo-1 6-Beta-Glucosidase; Glycoside Hydrolase Family; O-Glycosyl Hydrolase Family; Glycoside Hydrolase Family Protein; O-Glycosyl Hydrolase; Glycosyl Hydrolase; Ricin B Lectin; O-Glycosyl Hydrolase Family Protein; Glycoside Hydrolase; Lysosomal Glucosyl Ceramidase-Like Protein; Glycoside Hydrolase Family 5 Domain Protein; Endoxylanase; LPXTG-Motif Cell Wall Anchor Domain Protein; Cellulosome Protein Dockerin Type I; Glycosy Hydrolase Family Protein; Glucan EndO-1 6-Beta-Glucosidase; Helix-Turn-Helix AraC Type; Glycosyl Hydrolase Family; Glycosyl Hydrolases Family; Endo-1 6-Beta-D-Glucanase; Glucuronoarabinoxylan Endo-1 4-Beta-Xylanase

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKALIAILGLASFMAGGQQGSDAEVWLTTPDKSALFERQKQSPVLAAPGSRNPTIEIDERQKFQPIDGFGFALTGGSAQH
LVRMSAAARAAILKELFGTADREIGVSYLRLTIGASDLNDHVFTYDDMPDGQTDPDLQHFDLGPDKADVIPVMKEILKLN
PRIKILASPWTAPSWMKTNNNAKGGALKPEAYPAYAQYFVKYIRAMKAEGIAIDAITVQNEPLNPKNTPSLVMQSAEEAL
FIKSHLGPAFHAAGIKTHIVLYDHNCDVPEYATAILADRAAARYVDGSGFHLYGGKIEAMTQVHDQYPVKNLYFTEQMVV
GSVESKPAINIAAPVRRLIIGATRNWSRNVVLWNLAADPKNNPHTDDGGCGMCQGAITIDGDQVSRNLAYYAIAHASKFV
RPGAVRIASTSLESLPNVAFRTPSGKRVLIVVNASQTSQTFDIQAAKRMSATLPPGAVATYVW

Sequences:

>Translated_463_residues
MKALIAILGLASFMAGGQQGSDAEVWLTTPDKSALFERQKQSPVLAAPGSRNPTIEIDERQKFQPIDGFGFALTGGSAQH
LVRMSAAARAAILKELFGTADREIGVSYLRLTIGASDLNDHVFTYDDMPDGQTDPDLQHFDLGPDKADVIPVMKEILKLN
PRIKILASPWTAPSWMKTNNNAKGGALKPEAYPAYAQYFVKYIRAMKAEGIAIDAITVQNEPLNPKNTPSLVMQSAEEAL
FIKSHLGPAFHAAGIKTHIVLYDHNCDVPEYATAILADRAAARYVDGSGFHLYGGKIEAMTQVHDQYPVKNLYFTEQMVV
GSVESKPAINIAAPVRRLIIGATRNWSRNVVLWNLAADPKNNPHTDDGGCGMCQGAITIDGDQVSRNLAYYAIAHASKFV
RPGAVRIASTSLESLPNVAFRTPSGKRVLIVVNASQTSQTFDIQAAKRMSATLPPGAVATYVW
>Mature_463_residues
MKALIAILGLASFMAGGQQGSDAEVWLTTPDKSALFERQKQSPVLAAPGSRNPTIEIDERQKFQPIDGFGFALTGGSAQH
LVRMSAAARAAILKELFGTADREIGVSYLRLTIGASDLNDHVFTYDDMPDGQTDPDLQHFDLGPDKADVIPVMKEILKLN
PRIKILASPWTAPSWMKTNNNAKGGALKPEAYPAYAQYFVKYIRAMKAEGIAIDAITVQNEPLNPKNTPSLVMQSAEEAL
FIKSHLGPAFHAAGIKTHIVLYDHNCDVPEYATAILADRAAARYVDGSGFHLYGGKIEAMTQVHDQYPVKNLYFTEQMVV
GSVESKPAINIAAPVRRLIIGATRNWSRNVVLWNLAADPKNNPHTDDGGCGMCQGAITIDGDQVSRNLAYYAIAHASKFV
RPGAVRIASTSLESLPNVAFRTPSGKRVLIVVNASQTSQTFDIQAAKRMSATLPPGAVATYVW

Specific function: Unknown

COG id: COG5520

COG function: function code M; O-Glycosyl hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI284807150, Length=440, Percent_Identity=28.1818181818182, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI54607043, Length=440, Percent_Identity=28.1818181818182, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI54607045, Length=440, Percent_Identity=28.1818181818182, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI54607047, Length=440, Percent_Identity=28.1818181818182, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI284807152, Length=391, Percent_Identity=27.8772378516624, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI115532472, Length=441, Percent_Identity=29.7052154195011, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI115532470, Length=441, Percent_Identity=29.7052154195011, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17542884, Length=441, Percent_Identity=26.3038548752834, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17539756, Length=459, Percent_Identity=28.5403050108932, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17539758, Length=463, Percent_Identity=27.8617710583153, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI193204210, Length=404, Percent_Identity=29.7029702970297, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25151335, Length=383, Percent_Identity=29.242819843342, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI161078544, Length=439, Percent_Identity=25.2847380410023, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI21355305, Length=413, Percent_Identity=25.6658595641646, Blast_Score=112, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50190; Mature: 50190

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALIAILGLASFMAGGQQGSDAEVWLTTPDKSALFERQKQSPVLAAPGSRNPTIEIDER
CHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEECCCCCCCCEEECCC
QKFQPIDGFGFALTGGSAQHLVRMSAAARAAILKELFGTADREIGVSYLRLTIGASDLND
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEEECCCCCCC
HVFTYDDMPDGQTDPDLQHFDLGPDKADVIPVMKEILKLNPRIKILASPWTAPSWMKTNN
CEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCC
NAKGGALKPEAYPAYAQYFVKYIRAMKAEGIAIDAITVQNEPLNPKNTPSLVMQSAEEAL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHE
FIKSHLGPAFHAAGIKTHIVLYDHNCDVPEYATAILADRAAARYVDGSGFHLYGGKIEAM
EHHHHCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCEEEECCEEHHH
TQVHDQYPVKNLYFTEQMVVGSVESKPAINIAAPVRRLIIGATRNWSRNVVLWNLAADPK
HHHHHCCCCCCEEEEHHHEEECCCCCCCEEHHHHHHHHHEECCCCCCCCEEEEEEECCCC
NNPHTDDGGCGMCQGAITIDGDQVSRNLAYYAIAHASKFVRPGAVRIASTSLESLPNVAF
CCCCCCCCCCEEECCEEEECHHHHHCCHHEEEEEHHHHHCCCCCEEEEHHHHHHCCCEEE
RTPSGKRVLIVVNASQTSQTFDIQAAKRMSATLPPGAVATYVW
ECCCCCEEEEEEECCCCCCEEEHHHHHHHCCCCCCCCEEEECC
>Mature Secondary Structure
MKALIAILGLASFMAGGQQGSDAEVWLTTPDKSALFERQKQSPVLAAPGSRNPTIEIDER
CHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEECCCCCCCCEEECCC
QKFQPIDGFGFALTGGSAQHLVRMSAAARAAILKELFGTADREIGVSYLRLTIGASDLND
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEEECCCCCCC
HVFTYDDMPDGQTDPDLQHFDLGPDKADVIPVMKEILKLNPRIKILASPWTAPSWMKTNN
CEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCC
NAKGGALKPEAYPAYAQYFVKYIRAMKAEGIAIDAITVQNEPLNPKNTPSLVMQSAEEAL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHE
FIKSHLGPAFHAAGIKTHIVLYDHNCDVPEYATAILADRAAARYVDGSGFHLYGGKIEAM
EHHHHCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCEEEECCEEHHH
TQVHDQYPVKNLYFTEQMVVGSVESKPAINIAAPVRRLIIGATRNWSRNVVLWNLAADPK
HHHHHCCCCCCEEEEHHHEEECCCCCCCEEHHHHHHHHHEECCCCCCCCEEEEEEECCCC
NNPHTDDGGCGMCQGAITIDGDQVSRNLAYYAIAHASKFVRPGAVRIASTSLESLPNVAF
CCCCCCCCCCEEECCEEEECHHHHHCCHHEEEEEHHHHHCCCCCEEEEHHHHHHCCCEEE
RTPSGKRVLIVVNASQTSQTFDIQAAKRMSATLPPGAVATYVW
ECCCCCEEEEEEECCCCCCEEEHHHHHHHCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA