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The map label for this gene is tktB [C]

Identifier: 116621571

GI number: 116621571

Start: 3115184

End: 3116005

Strand: Reverse

Name: tktB [C]

Synonym: Acid_2453

Alternate gene names: 116621571

Gene position: 3116005-3115184 (Counterclockwise)

Preceding gene: 116621572

Following gene: 116621570

Centisome position: 31.27

GC content: 60.95

Gene sequence:

>822_bases
ATGGCCAAATCCATTGATGAATTACAAAGCATAGCCAAGCGTGTACGGCGCGACATCGTCGAGATGATCACGACCGCCAA
ATCGGGGCATCCCGGTGGGTCGCTATCGGCTGTAGAGATTCTTGTCGAGCTGTACTTCGATCACATGAAGATTGACCCGG
CGAACCCGAAGTGGGCGGATCGCGACCGGTTCATTCTGTCGAAGGGGCATGCGGCCCCGGTGTTGTACAGCGTGATGGCG
GAGCGCGGGTACGCGGACACGCCGAAGGAGAAGCTGAATACGTTGCGGCAGTTCGGTTCGGTGTTCCAGGGACATCCGGA
TATGCGATTTATTCCGAGCCTGGAGGCATCGACGGGGTCGCTCGGGCAGGGACTTTCGCTGGGGCTCGGCATGGCGCTGG
GGGCGCGGCTAGACGGGCGCGCGTCGCGGACCTTCGTGATGTTGGGCGACGGCGAGATTCAGGAAGGACAGATCTGGGAA
GCGGCGATGGCGGCGGCGTTCCTGAAGGCGGACAACCTGGTGGCGATTGTGGATTACAACCAGATTCAGCTGGACGGCTT
CGTGAAGGACATCATGGACGTGGCTCCGCTGGCGGAGAAATGGCGGTCGTTCGGCTGGCACACGCTGGAAATCGACGGCC
ACAGTTTCGAGGCGATTCAAGCGGCGCTGGCGGAAGCGGCGGCGACCAAGGGCAAGCCGACCTGCCTGGTGGCGCACACG
GTGAAAGGCAAAGGCGTGTCCTTCATGGAAAACAATCCGAAGTATCACGGCATGGCGCCGACCAAGGATGAGCGCGAACT
GGCGCTTCAGGAGCTGAACTAA

Upstream 100 bases:

>100_bases
GAAATTGTGGTTTACACGAATTCTTCGCGGGCTGCAAACAAAGTAAGGCACAGTAGCACTAAGGCGGTCGTTGGCTAGCT
GCTAAGATTAGTAGTTTCAC

Downstream 100 bases:

>100_bases
TGGCCACCGAAACCAAGACTGCCAAGAGCAAATTCGAGATCAAGCCGGGCGCCGCCACGCGCGAGGCTTTCGGGCGCACG
CTGGTGGAGCTGGGCCGGGA

Product: transketolase subunit A

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MAKSIDELQSIAKRVRRDIVEMITTAKSGHPGGSLSAVEILVELYFDHMKIDPANPKWADRDRFILSKGHAAPVLYSVMA
ERGYADTPKEKLNTLRQFGSVFQGHPDMRFIPSLEASTGSLGQGLSLGLGMALGARLDGRASRTFVMLGDGEIQEGQIWE
AAMAAAFLKADNLVAIVDYNQIQLDGFVKDIMDVAPLAEKWRSFGWHTLEIDGHSFEAIQAALAEAAATKGKPTCLVAHT
VKGKGVSFMENNPKYHGMAPTKDERELALQELN

Sequences:

>Translated_273_residues
MAKSIDELQSIAKRVRRDIVEMITTAKSGHPGGSLSAVEILVELYFDHMKIDPANPKWADRDRFILSKGHAAPVLYSVMA
ERGYADTPKEKLNTLRQFGSVFQGHPDMRFIPSLEASTGSLGQGLSLGLGMALGARLDGRASRTFVMLGDGEIQEGQIWE
AAMAAAFLKADNLVAIVDYNQIQLDGFVKDIMDVAPLAEKWRSFGWHTLEIDGHSFEAIQAALAEAAATKGKPTCLVAHT
VKGKGVSFMENNPKYHGMAPTKDERELALQELN
>Mature_272_residues
AKSIDELQSIAKRVRRDIVEMITTAKSGHPGGSLSAVEILVELYFDHMKIDPANPKWADRDRFILSKGHAAPVLYSVMAE
RGYADTPKEKLNTLRQFGSVFQGHPDMRFIPSLEASTGSLGQGLSLGLGMALGARLDGRASRTFVMLGDGEIQEGQIWEA
AMAAAFLKADNLVAIVDYNQIQLDGFVKDIMDVAPLAEKWRSFGWHTLEIDGHSFEAIQAALAEAAATKGKPTCLVAHTV
KGKGVSFMENNPKYHGMAPTKDERELALQELN

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=276, Percent_Identity=38.768115942029, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4507521, Length=276, Percent_Identity=38.768115942029, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI133778974, Length=271, Percent_Identity=38.0073800738007, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI225637459, Length=270, Percent_Identity=30.3703703703704, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI225637461, Length=270, Percent_Identity=29.6296296296296, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI225637463, Length=230, Percent_Identity=30.4347826086957, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1788808, Length=280, Percent_Identity=35, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI48994911, Length=272, Percent_Identity=36.0294117647059, Blast_Score=158, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17539652, Length=253, Percent_Identity=43.0830039525692, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6325331, Length=270, Percent_Identity=37.037037037037, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319593, Length=257, Percent_Identity=34.2412451361868, Blast_Score=135, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24666278, Length=273, Percent_Identity=39.1941391941392, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI45551847, Length=257, Percent_Identity=37.7431906614786, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI45550715, Length=257, Percent_Identity=37.7431906614786, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24645119, Length=215, Percent_Identity=39.0697674418605, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 29826; Mature: 29695

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSIDELQSIAKRVRRDIVEMITTAKSGHPGGSLSAVEILVELYFDHMKIDPANPKWAD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCC
RDRFILSKGHAAPVLYSVMAERGYADTPKEKLNTLRQFGSVFQGHPDMRFIPSLEASTGS
CCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
LGQGLSLGLGMALGARLDGRASRTFVMLGDGEIQEGQIWEAAMAAAFLKADNLVAIVDYN
CCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC
QIQLDGFVKDIMDVAPLAEKWRSFGWHTLEIDGHSFEAIQAALAEAAATKGKPTCLVAHT
EEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEE
VKGKGVSFMENNPKYHGMAPTKDERELALQELN
ECCCCCEEECCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AKSIDELQSIAKRVRRDIVEMITTAKSGHPGGSLSAVEILVELYFDHMKIDPANPKWAD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCC
RDRFILSKGHAAPVLYSVMAERGYADTPKEKLNTLRQFGSVFQGHPDMRFIPSLEASTGS
CCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
LGQGLSLGLGMALGARLDGRASRTFVMLGDGEIQEGQIWEAAMAAAFLKADNLVAIVDYN
CCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC
QIQLDGFVKDIMDVAPLAEKWRSFGWHTLEIDGHSFEAIQAALAEAAATKGKPTCLVAHT
EEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEE
VKGKGVSFMENNPKYHGMAPTKDERELALQELN
ECCCCCEEECCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]