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The map label for this gene is sigW [H]

Identifier: 116621439

GI number: 116621439

Start: 2966492

End: 2967064

Strand: Direct

Name: sigW [H]

Synonym: Acid_2321

Alternate gene names: 116621439

Gene position: 2966492-2967064 (Clockwise)

Preceding gene: 116621437

Following gene: 116621440

Centisome position: 29.77

GC content: 65.27

Gene sequence:

>573_bases
ATGATTTACCAATCGGCAATCGATAGCGATTCTCAAGTGGCGGAACCATCCGAGCTCGCCCGCTTGCGCAGCGGAGACCC
CGCGGCGCTGGCCGCCGTGGTGGGCCGCTACCAGCACCGCCTGTATCGTTATTTCCTGCGACTGCTGCACGACCCGGCCG
CCGCCGACGACCTGTTCCAGCAGACCTGGCTCCAGGTGGTCCGCAATCTGCGTCGCTACGATGCCGGGCGCAGCTTCGAC
ACCTGGCTGTTCGCCATCGCCCACAATGCCGCGATGGACCTGCTGCGCCGCCGTCCCGGCGAATCGCTGGAAGAGCACGA
GGGGGAATTTCGCTCACCGGCCCCCGACGCTCTTGCCTCCGTGCTGGCAGGCGAACGTGCGGCGATTTTGGCTGCGGCTA
TGAATACGCTGCCGGCGCTGTACCGGGAGGCGCTGACGCTGCGCTTCGAAGAGGGCATGAAGCTCGAAGAGATCGCCGAG
GTCACGCACGCGCCGCTATCGACGGTTAAGAGCCGGGTGCAGCGCGGCCTCGAAGCGCTCCGCCAGAAAATCTCCACGGA
AGGTATCCTATGA

Upstream 100 bases:

>100_bases
GATCCATAACACCGCTTAGGAAGGACTCATCTTATCACCACTGCGCCCCCGCGCCGAGAGGCGTCTTTTTCCGGGTGTCA
TCCGTATACCCAATGCGGCT

Downstream 100 bases:

>100_bases
CCGATCACGACCTGGTCCGCCCGCTGTTTGCGCTGAGCGCCGCCGGCCTGCTGGATGCGGAAGGCGAGCGGCGCCTGCGC
GAGCATACCGCCGGGTGCGA

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIYQSAIDSDSQVAEPSELARLRSGDPAALAAVVGRYQHRLYRYFLRLLHDPAAADDLFQQTWLQVVRNLRRYDAGRSFD
TWLFAIAHNAAMDLLRRRPGESLEEHEGEFRSPAPDALASVLAGERAAILAAAMNTLPALYREALTLRFEEGMKLEEIAE
VTHAPLSTVKSRVQRGLEALRQKISTEGIL

Sequences:

>Translated_190_residues
MIYQSAIDSDSQVAEPSELARLRSGDPAALAAVVGRYQHRLYRYFLRLLHDPAAADDLFQQTWLQVVRNLRRYDAGRSFD
TWLFAIAHNAAMDLLRRRPGESLEEHEGEFRSPAPDALASVLAGERAAILAAAMNTLPALYREALTLRFEEGMKLEEIAE
VTHAPLSTVKSRVQRGLEALRQKISTEGIL
>Mature_190_residues
MIYQSAIDSDSQVAEPSELARLRSGDPAALAAVVGRYQHRLYRYFLRLLHDPAAADDLFQQTWLQVVRNLRRYDAGRSFD
TWLFAIAHNAAMDLLRRRPGESLEEHEGEFRSPAPDALASVLAGERAAILAAAMNTLPALYREALTLRFEEGMKLEEIAE
VTHAPLSTVKSRVQRGLEALRQKISTEGIL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=9e-16,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21286; Mature: 21286

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYQSAIDSDSQVAEPSELARLRSGDPAALAAVVGRYQHRLYRYFLRLLHDPAAADDLFQ
CCCCCCCCCCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QTWLQVVRNLRRYDAGRSFDTWLFAIAHNAAMDLLRRRPGESLEEHEGEFRSPAPDALAS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHH
VLAGERAAILAAAMNTLPALYREALTLRFEEGMKLEEIAEVTHAPLSTVKSRVQRGLEAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RQKISTEGIL
HHHHHHCCCC
>Mature Secondary Structure
MIYQSAIDSDSQVAEPSELARLRSGDPAALAAVVGRYQHRLYRYFLRLLHDPAAADDLFQ
CCCCCCCCCCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QTWLQVVRNLRRYDAGRSFDTWLFAIAHNAAMDLLRRRPGESLEEHEGEFRSPAPDALAS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHH
VLAGERAAILAAAMNTLPALYREALTLRFEEGMKLEEIAEVTHAPLSTVKSRVQRGLEAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RQKISTEGIL
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]