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The map label for this gene is yqjE [H]

Identifier: 116621413

GI number: 116621413

Start: 2933528

End: 2934754

Strand: Reverse

Name: yqjE [H]

Synonym: Acid_2295

Alternate gene names: 116621413

Gene position: 2934754-2933528 (Counterclockwise)

Preceding gene: 116621417

Following gene: 116621410

Centisome position: 29.45

GC content: 65.2

Gene sequence:

>1227_bases
ATGAGGCTCTCGGCAATCCTTCTTTCCCTGTCCGCGGTGTGTCTGGCGCAGGCGCCGGCGGAGTTGATGAACGATCGCGC
GGTTCGCGCGGCGATGGATGCGGCGCGGCGCAATGAGCCGGCGACACTCGACCTGCAGGCGCGGATCTGCGAGATCCCTG
CGCCGCCGTACAAGGAGGAGGTCCGGGGGCTCGAGCTCAAGCGACTGTTCGAGCAGCTGGGGCTGCGCGACGTCCGCATC
GATAAAGCGGGCAACGTGATCGGCGTGCGTCCCGGCAAGGCGGCGCATCCCAACCTCGTCTTCAGCGCGCATCTCGATAC
GGTTTTTCCGGAAGGCACTAACGTGAAGGTGACGCGCGAGGGCGAGGTCATGAAAGCTCCGGGGATCGGCGACGATTGCC
GCGGACTGGCGGTGATGCTGGCGGTGATCCGCGCGTTGAACGATGGGCACGTGGAGACGCCGGGAACCATTACGTTCGTG
GCCGACGTCGGCGAGGAAGGGCTCGGCGATCTTCGGGGGATGAAGAGTCTCTTCTTCGACAGCCTCAAGGGGCAGATCGA
TAAATTCATTTCGGTGGATGGGACGGGGCTGGGGATCACGCACATCGGCGTGGGGAGCAACCGGTACAAGGTAGTGTTCA
AGGGACCGGGCGGGCACAGCTACGGCGCGTTCGGCATGGCCAATCCGATTCAGGCGATGGGCCGTGCGATCGCAAAGATC
GACGCCATCGAAGTTCCGCGGCAGCCCAAGACGACGTTTAATGTCGGGCGCGTGGGCGGCGGTACTTCGATCAATGCGAT
TCCGTTCGAGGCTTGGATGGAGGTGGACATGCGGTCGGCCGACCCTGCCGCGCTCAAGGCGGTGGACACTGAATTTCATG
CGGCGATCGACCAGGCGGTGGCGGAGGAGAACGCGCGGTGGAATAATCGCGGGCCGGTGAGCGCGTCGGCCGAGCTGGTC
GGGGTGCGGCCGGCGGGGCAGACGGCGAAGGAGAGCGCGATCGTGCAGACGGCAATGGCGGTGTCGCGCGCGATGCAGAT
TGAGGAAGTGCTGCGCGAGGGCTCCACCGATTCGAACGTGCCGATGAATCTCAATATCCCGGCGATCACGATCAGCGGGG
GCGGTAATGGCGCGGGGGCGCACTCGCTGAATGAGACGTTCGACGCGAAGGATTCGTGGCGGGGCACGCAGCGGGCGCTG
TTGCTGGCGATCGCGCTGGCGCGATAA

Upstream 100 bases:

>100_bases
AACCAAGCCTCCTGGAATCTTCGCGGCCTGCGAGCAAACAAATGCACGGTGCAGTGCGGCGCGACAGGGCGGTTGGGAGT
CGCAGGGTACACTGGATCCA

Downstream 100 bases:

>100_bases
GTCGGGGCGCAGTTGTGCCATTAGTTGGGGGAACACTTGTTCGTTGCGGCGGCCGGGGACATACGGTCTTATCGCCGGGT
GGGGCCCGGCCGCCAGTGAT

Product: peptidase M20

Products: Hydrolysed Xaa-|-His Dipeptides [C]

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRLSAILLSLSAVCLAQAPAELMNDRAVRAAMDAARRNEPATLDLQARICEIPAPPYKEEVRGLELKRLFEQLGLRDVRI
DKAGNVIGVRPGKAAHPNLVFSAHLDTVFPEGTNVKVTREGEVMKAPGIGDDCRGLAVMLAVIRALNDGHVETPGTITFV
ADVGEEGLGDLRGMKSLFFDSLKGQIDKFISVDGTGLGITHIGVGSNRYKVVFKGPGGHSYGAFGMANPIQAMGRAIAKI
DAIEVPRQPKTTFNVGRVGGGTSINAIPFEAWMEVDMRSADPAALKAVDTEFHAAIDQAVAEENARWNNRGPVSASAELV
GVRPAGQTAKESAIVQTAMAVSRAMQIEEVLREGSTDSNVPMNLNIPAITISGGGNGAGAHSLNETFDAKDSWRGTQRAL
LLAIALAR

Sequences:

>Translated_408_residues
MRLSAILLSLSAVCLAQAPAELMNDRAVRAAMDAARRNEPATLDLQARICEIPAPPYKEEVRGLELKRLFEQLGLRDVRI
DKAGNVIGVRPGKAAHPNLVFSAHLDTVFPEGTNVKVTREGEVMKAPGIGDDCRGLAVMLAVIRALNDGHVETPGTITFV
ADVGEEGLGDLRGMKSLFFDSLKGQIDKFISVDGTGLGITHIGVGSNRYKVVFKGPGGHSYGAFGMANPIQAMGRAIAKI
DAIEVPRQPKTTFNVGRVGGGTSINAIPFEAWMEVDMRSADPAALKAVDTEFHAAIDQAVAEENARWNNRGPVSASAELV
GVRPAGQTAKESAIVQTAMAVSRAMQIEEVLREGSTDSNVPMNLNIPAITISGGGNGAGAHSLNETFDAKDSWRGTQRAL
LLAIALAR
>Mature_408_residues
MRLSAILLSLSAVCLAQAPAELMNDRAVRAAMDAARRNEPATLDLQARICEIPAPPYKEEVRGLELKRLFEQLGLRDVRI
DKAGNVIGVRPGKAAHPNLVFSAHLDTVFPEGTNVKVTREGEVMKAPGIGDDCRGLAVMLAVIRALNDGHVETPGTITFV
ADVGEEGLGDLRGMKSLFFDSLKGQIDKFISVDGTGLGITHIGVGSNRYKVVFKGPGGHSYGAFGMANPIQAMGRAIAKI
DAIEVPRQPKTTFNVGRVGGGTSINAIPFEAWMEVDMRSADPAALKAVDTEFHAAIDQAVAEENARWNNRGPVSASAELV
GVRPAGQTAKESAIVQTAMAVSRAMQIEEVLREGSTDSNVPMNLNIPAITISGGGNGAGAHSLNETFDAKDSWRGTQRAL
LLAIALAR

Specific function: Could be a peptidase [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010162
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3 [C]

Molecular weight: Translated: 43234; Mature: 43234

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00318 HMG_COA_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSAILLSLSAVCLAQAPAELMNDRAVRAAMDAARRNEPATLDLQARICEIPAPPYKEE
CCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHH
VRGLELKRLFEQLGLRDVRIDKAGNVIGVRPGKAAHPNLVFSAHLDTVFPEGTNVKVTRE
HCCCHHHHHHHHHCCEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEEC
GEVMKAPGIGDDCRGLAVMLAVIRALNDGHVETPGTITFVADVGEEGLGDLRGMKSLFFD
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
SLKGQIDKFISVDGTGLGITHIGVGSNRYKVVFKGPGGHSYGAFGMANPIQAMGRAIAKI
HHHHHHHHHEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
DAIEVPRQPKTTFNVGRVGGGTSINAIPFEAWMEVDMRSADPAALKAVDTEFHAAIDQAV
HHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEENARWNNRGPVSASAELVGVRPAGQTAKESAIVQTAMAVSRAMQIEEVLREGSTDSNV
HHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PMNLNIPAITISGGGNGAGAHSLNETFDAKDSWRGTQRALLLAIALAR
CEEECCCEEEEECCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLSAILLSLSAVCLAQAPAELMNDRAVRAAMDAARRNEPATLDLQARICEIPAPPYKEE
CCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHH
VRGLELKRLFEQLGLRDVRIDKAGNVIGVRPGKAAHPNLVFSAHLDTVFPEGTNVKVTRE
HCCCHHHHHHHHHCCEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEEC
GEVMKAPGIGDDCRGLAVMLAVIRALNDGHVETPGTITFVADVGEEGLGDLRGMKSLFFD
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
SLKGQIDKFISVDGTGLGITHIGVGSNRYKVVFKGPGGHSYGAFGMANPIQAMGRAIAKI
HHHHHHHHHEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
DAIEVPRQPKTTFNVGRVGGGTSINAIPFEAWMEVDMRSADPAALKAVDTEFHAAIDQAV
HHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEENARWNNRGPVSASAELVGVRPAGQTAKESAIVQTAMAVSRAMQIEEVLREGSTDSNV
HHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PMNLNIPAITISGGGNGAGAHSLNETFDAKDSWRGTQRALLLAIALAR
CEEECCCEEEEECCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Xaa-|-His Dipeptides [C]

Specific reaction: Hydrolysis Of Xaa-|-His Dipeptides. [C]

General reaction: Carboxylic acid amide hydrolysis (dipeptide hydrolase [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]