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The map label for this gene is resA [H]

Identifier: 116621401

GI number: 116621401

Start: 2916573

End: 2918078

Strand: Reverse

Name: resA [H]

Synonym: Acid_2283

Alternate gene names: 116621401

Gene position: 2918078-2916573 (Counterclockwise)

Preceding gene: 116621402

Following gene: 116621400

Centisome position: 29.28

GC content: 65.14

Gene sequence:

>1506_bases
ATGAAGTCCCGACTGGTTCTCACCACACTTGCATTCGCGGGCGCTATCTGCGCGGCCGATACGACGGTAGCGCAGACCGC
CGCGAAGCTGGAAGAGCAACTTACCACGGCGCCCGGGTCGATCGGGGCGGAATACCGGCTGGGCGCGGCTCAGGCATTGC
AGGCGGGCTACCCGGAGCTCTCGCGCAGGTTTCTGGAGACTGCGCTGAAGTCGCTTCGCGGCAGCAAGGATGTTCCGGAG
CCGGCGGTGTGGCAGGCGCTGGCGGAAATGGCGCCCGCGGAGGCGGCCGCGCTCGCACCGCAGTTTGGGTCCGGCGGCAC
GCTGCTGGCGATCACGACCCTGGTGCGCGAGGGACATGCGGACGAGGCGGCGGCGCTGTACAGGAAGACCGCTGCCTCCT
TCGCCGAGCCGTTGAGCTTCGCGGATGCGAACTGGCTGGTCAACGCGTCGGGTCCGCTGGCGAAGACCTTGCCGGATGCG
GTTGCGGATAATTACGAGCGCGCGATTCGCGCCGCGTCGGCGTCGCCGGATTTCGGAGGCGACGTGAAGATGACGCGCAC
GATCCAGGTTGGGACAACATCGATCACGACCGATAATGCGCGCGACACGCTGCTGATTCTGGCGGGCGCGCGGCTGCGGC
TGCTCTCGCCGGAGCGCTTCGCGAAATACCGGGAGACCTTTTCGAAGTGGAATCTCACCGGCCCCGCGACGGTGCGGAGC
GCAGGGGCGCCCGCGTCGCCTGAAGTGGCGTCGATCTCTAACCGCATGGGTACGATGCGGAAGCTGCCGAGCGACCGGGA
TCGGACGCAGCTGGTGAAAGAGCTGGTTCCCGAGATTCGCAAGCTGCCACTGCAATGGCGGCTGGGTTTGATTCGCGGGC
TGGCGGGCGTGGCGACGGAGGGCGACCTCGGGAAGGAGGCGCTGGGAATGGTCGCGGTTACGCTGGCGGACACGCTGAGG
GAAGCGTCGCAGGGGCCGGGCTCGTACGGCGACAGCTATCTCGGACTTGCGAAAATGGTGCGCTACGAACATCTCACGGT
GCCCACCGACCCTACGCTTGCAGCGGCGCAGGCGTTGCTGGCATTGCGCGAGCAGGTACAGCAGGAGAACGGCTTCAGCC
TGACGAGCCTGGACGGCAAGACGTATACGCTGGCGGGATTGAAGGGCAAGATCGTGCTGTTGAACTTCTGGGCGACGTGG
TGCCCGCCGTGCCGGAAGGAAATGCCCGACATGGAGAAGCTGTACCGGACATATGAGAAGCAGGGGTTGACGGTGATTGC
GGTGTCGGACGAAGACCGCGAGACGGTGGCGAATTTCCTGGCGAAGAATAACTATAGTTTTCCGATTGCGCTGGATGCGG
GGCGGAAGGTAAATAGCGCGTTCCTGGTGGAAGGGATCCCGCAGAGCTTCATTTTCGATCGCGAAGGGCGGCTCGCGGCG
CAGGCGATCGATATGCGGACCGAGGGACAGTTTATGGAACTGCTGCGGCGGGCCGGGCTGGAGTAG

Upstream 100 bases:

>100_bases
GGCGGGCCGCAGGGGAAGTCGCAGGCGCCGGCGCCGAAGAAGTCCGCGCCGGCGAAAAAGGCCGGAAAGCTCTGATATAC
TCCGCCACAGGAGAGTCCGC

Downstream 100 bases:

>100_bases
GGAGGCCTGTCCCAGTCTCGGGAGCTTTGATAGACTAAGCGGGTCGTGAGCTCGTCCCCGGTATTTCGATGTCCTACCTG
CGGCAGTCTCGACTGTCGGC

Product: redoxin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKSRLVLTTLAFAGAICAADTTVAQTAAKLEEQLTTAPGSIGAEYRLGAAQALQAGYPELSRRFLETALKSLRGSKDVPE
PAVWQALAEMAPAEAAALAPQFGSGGTLLAITTLVREGHADEAAALYRKTAASFAEPLSFADANWLVNASGPLAKTLPDA
VADNYERAIRAASASPDFGGDVKMTRTIQVGTTSITTDNARDTLLILAGARLRLLSPERFAKYRETFSKWNLTGPATVRS
AGAPASPEVASISNRMGTMRKLPSDRDRTQLVKELVPEIRKLPLQWRLGLIRGLAGVATEGDLGKEALGMVAVTLADTLR
EASQGPGSYGDSYLGLAKMVRYEHLTVPTDPTLAAAQALLALREQVQQENGFSLTSLDGKTYTLAGLKGKIVLLNFWATW
CPPCRKEMPDMEKLYRTYEKQGLTVIAVSDEDRETVANFLAKNNYSFPIALDAGRKVNSAFLVEGIPQSFIFDREGRLAA
QAIDMRTEGQFMELLRRAGLE

Sequences:

>Translated_501_residues
MKSRLVLTTLAFAGAICAADTTVAQTAAKLEEQLTTAPGSIGAEYRLGAAQALQAGYPELSRRFLETALKSLRGSKDVPE
PAVWQALAEMAPAEAAALAPQFGSGGTLLAITTLVREGHADEAAALYRKTAASFAEPLSFADANWLVNASGPLAKTLPDA
VADNYERAIRAASASPDFGGDVKMTRTIQVGTTSITTDNARDTLLILAGARLRLLSPERFAKYRETFSKWNLTGPATVRS
AGAPASPEVASISNRMGTMRKLPSDRDRTQLVKELVPEIRKLPLQWRLGLIRGLAGVATEGDLGKEALGMVAVTLADTLR
EASQGPGSYGDSYLGLAKMVRYEHLTVPTDPTLAAAQALLALREQVQQENGFSLTSLDGKTYTLAGLKGKIVLLNFWATW
CPPCRKEMPDMEKLYRTYEKQGLTVIAVSDEDRETVANFLAKNNYSFPIALDAGRKVNSAFLVEGIPQSFIFDREGRLAA
QAIDMRTEGQFMELLRRAGLE
>Mature_501_residues
MKSRLVLTTLAFAGAICAADTTVAQTAAKLEEQLTTAPGSIGAEYRLGAAQALQAGYPELSRRFLETALKSLRGSKDVPE
PAVWQALAEMAPAEAAALAPQFGSGGTLLAITTLVREGHADEAAALYRKTAASFAEPLSFADANWLVNASGPLAKTLPDA
VADNYERAIRAASASPDFGGDVKMTRTIQVGTTSITTDNARDTLLILAGARLRLLSPERFAKYRETFSKWNLTGPATVRS
AGAPASPEVASISNRMGTMRKLPSDRDRTQLVKELVPEIRKLPLQWRLGLIRGLAGVATEGDLGKEALGMVAVTLADTLR
EASQGPGSYGDSYLGLAKMVRYEHLTVPTDPTLAAAQALLALREQVQQENGFSLTSLDGKTYTLAGLKGKIVLLNFWATW
CPPCRKEMPDMEKLYRTYEKQGLTVIAVSDEDRETVANFLAKNNYSFPIALDAGRKVNSAFLVEGIPQSFIFDREGRLAA
QAIDMRTEGQFMELLRRAGLE

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 53958; Mature: 53958

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRLVLTTLAFAGAICAADTTVAQTAAKLEEQLTTAPGSIGAEYRLGAAQALQAGYPEL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHCCCHHH
SRRFLETALKSLRGSKDVPEPAVWQALAEMAPAEAAALAPQFGSGGTLLAITTLVREGHA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHCCCC
DEAAALYRKTAASFAEPLSFADANWLVNASGPLAKTLPDAVADNYERAIRAASASPDFGG
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVKMTRTIQVGTTSITTDNARDTLLILAGARLRLLSPERFAKYRETFSKWNLTGPATVRS
CEEEEEEEEECCEEEECCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCHHHHC
AGAPASPEVASISNRMGTMRKLPSDRDRTQLVKELVPEIRKLPLQWRLGLIRGLAGVATE
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
GDLGKEALGMVAVTLADTLREASQGPGSYGDSYLGLAKMVRYEHLTVPTDPTLAAAQALL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ALREQVQQENGFSLTSLDGKTYTLAGLKGKIVLLNFWATWCPPCRKEMPDMEKLYRTYEK
HHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEECCHHHCCHHHHCCCCHHHHHHHHHH
QGLTVIAVSDEDRETVANFLAKNNYSFPIALDAGRKVNSAFLVEGIPQSFIFDREGRLAA
CCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHEECCCCHHHEECCCCCHHH
QAIDMRTEGQFMELLRRAGLE
HHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKSRLVLTTLAFAGAICAADTTVAQTAAKLEEQLTTAPGSIGAEYRLGAAQALQAGYPEL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHCCCHHH
SRRFLETALKSLRGSKDVPEPAVWQALAEMAPAEAAALAPQFGSGGTLLAITTLVREGHA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHCCCC
DEAAALYRKTAASFAEPLSFADANWLVNASGPLAKTLPDAVADNYERAIRAASASPDFGG
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVKMTRTIQVGTTSITTDNARDTLLILAGARLRLLSPERFAKYRETFSKWNLTGPATVRS
CEEEEEEEEECCEEEECCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCHHHHC
AGAPASPEVASISNRMGTMRKLPSDRDRTQLVKELVPEIRKLPLQWRLGLIRGLAGVATE
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
GDLGKEALGMVAVTLADTLREASQGPGSYGDSYLGLAKMVRYEHLTVPTDPTLAAAQALL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ALREQVQQENGFSLTSLDGKTYTLAGLKGKIVLLNFWATWCPPCRKEMPDMEKLYRTYEK
HHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEECCHHHCCHHHHCCCCHHHHHHHHHH
QGLTVIAVSDEDRETVANFLAKNNYSFPIALDAGRKVNSAFLVEGIPQSFIFDREGRLAA
CCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHEECCCCHHHEECCCCCHHH
QAIDMRTEGQFMELLRRAGLE
HHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA