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The map label for this gene is steT [H]

Identifier: 116621243

GI number: 116621243

Start: 2723534

End: 2724922

Strand: Direct

Name: steT [H]

Synonym: Acid_2124

Alternate gene names: 116621243

Gene position: 2723534-2724922 (Clockwise)

Preceding gene: 116621242

Following gene: 116621244

Centisome position: 27.33

GC content: 64.58

Gene sequence:

>1389_bases
ATGCAACTTGGCGGTAGCGAAGGCTCGGCGAGGATTCGGGATTGCCGGCACCCCGCTCCGCCCATCATCTCTCCATGCAA
TCATGGTCGAAACATGCCATCCGAACTTCCCCGCCGGCTAGGCCTGCTCGATTCCTCTGCCATAGTCGTCGGCACCATCA
TCGGCTCCGGCATCTTTCTCGTTCCCAACCTTGTCGCCCGCAGCCTCCCCTCCGCCCCCTGGATCATCGCCGTCTGGATT
TTCACCGGCGCCCTCTCCTTCTTCGGAGCCCTCGCCTACGCCGAACTCGGCGCCATGATCCCGGCCACCGGGGGCCAGTA
CGTCTTCCTGCGCGAAGCCTACGGTCCTCTGTGGGGCTTCCTCTGCGGCTGGACTTACTTCTTCGTCGTCATCTCCGCCG
CCATCGGCTGGCTCGCCATCACCTTCGCCACATACCTCGGCTACTTCATCCCGCTCACCCCCGCTCTTTCTAAACTCGTC
GCCATCACTTTGATTGCGGCAATCACGTTCGTCAACTATCGCGGCATCACGCTCGGCGCCACCGTGCAGAAGCTCTTCAC
CTTCACGAAGGTCGCTGCCCTTGCCATCCTCGTAGCCGCGGCCTTCGTCGGTCCCGCGCATGCCGTTTCCGAAAACGCTG
CCGGCCCCGTCACCCTCAGCGGCTTCGGCGTCGCCATGATCTCCTGCCTGCTCAGTTACGATGGCTGGGTCGCCCTCAGC
TTCGTCGCCGGCGAGGTCCGCGACCCCAAGCGCACGCTACCTCTCGCGCTCGCCCTCGGAGTGGGCGGCGCCATTGCCAT
CTACGTGCTCGCCAACATCGCCTATCTGCGCGTCCTCTCCGTCGGCGAGATTGCCGCCACCGCTCGCGTCGGAGCCCTCG
CCGCGGAGCGCACTATGGGCCCCACCGGCGGAGCTTTCGTCTCCTTCTCCATCCTTATGTCGATCGTCGGCGCCATCAAC
GGCTGGGTCCTTGCCGCCCCGCGCATTTACTTCGCCCAGGCCCGGGACGGCCTCTTCTTCAGAAGCTTCGCCGCCATCCA
CCCCAGATTCCAGACGCCCTACGTCTCCATCCTCACTTTCGGCGCGTGGTCTGCCCTCCTTGCCATCACCGGCACCTACG
AGACCCTTGCCTCCTACGCCATGTATGCCGCCTGGGTGTTCTATGCCCTCACCGCGCTCGCCGTCATCGCCCTCCGCCGC
CGGCAGCCGGACCGCCCCCGCCCCTATCGCATGACCGGCTATCCCGTTACCCTGCTGATCTTTGCCGCGGTCGCCTTCGG
CTTTGTTATCAATACCTTCTATGCGACCCCCGGTCCCGCGATCGTCGGCACGCTTTTGATTGGGGCCGGAGTCCCGGTAT
ACTTCATTTGGAGGGGAACGGCAGGGTGA

Upstream 100 bases:

>100_bases
GCCGACGGGCGGCATCTAGGAAATTTCCCGCAAGCGTTCACGCACCTCGCGCTGATCAGCGCGGCGACTTATCTCGACCG
GGCTCTATCGGGCCCAAACG

Downstream 100 bases:

>100_bases
TTCAAACCGGCACGCAAGTGGGGCTCTCGTATGAGCCGCGTCCGGCCTTCGCGCAGTTTGCCGACCCGGCGATTGCCGAT
TGCGAAGGCAAACGCATCGG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MQLGGSEGSARIRDCRHPAPPIISPCNHGRNMPSELPRRLGLLDSSAIVVGTIIGSGIFLVPNLVARSLPSAPWIIAVWI
FTGALSFFGALAYAELGAMIPATGGQYVFLREAYGPLWGFLCGWTYFFVVISAAIGWLAITFATYLGYFIPLTPALSKLV
AITLIAAITFVNYRGITLGATVQKLFTFTKVAALAILVAAAFVGPAHAVSENAAGPVTLSGFGVAMISCLLSYDGWVALS
FVAGEVRDPKRTLPLALALGVGGAIAIYVLANIAYLRVLSVGEIAATARVGALAAERTMGPTGGAFVSFSILMSIVGAIN
GWVLAAPRIYFAQARDGLFFRSFAAIHPRFQTPYVSILTFGAWSALLAITGTYETLASYAMYAAWVFYALTALAVIALRR
RQPDRPRPYRMTGYPVTLLIFAAVAFGFVINTFYATPGPAIVGTLLIGAGVPVYFIWRGTAG

Sequences:

>Translated_462_residues
MQLGGSEGSARIRDCRHPAPPIISPCNHGRNMPSELPRRLGLLDSSAIVVGTIIGSGIFLVPNLVARSLPSAPWIIAVWI
FTGALSFFGALAYAELGAMIPATGGQYVFLREAYGPLWGFLCGWTYFFVVISAAIGWLAITFATYLGYFIPLTPALSKLV
AITLIAAITFVNYRGITLGATVQKLFTFTKVAALAILVAAAFVGPAHAVSENAAGPVTLSGFGVAMISCLLSYDGWVALS
FVAGEVRDPKRTLPLALALGVGGAIAIYVLANIAYLRVLSVGEIAATARVGALAAERTMGPTGGAFVSFSILMSIVGAIN
GWVLAAPRIYFAQARDGLFFRSFAAIHPRFQTPYVSILTFGAWSALLAITGTYETLASYAMYAAWVFYALTALAVIALRR
RQPDRPRPYRMTGYPVTLLIFAAVAFGFVINTFYATPGPAIVGTLLIGAGVPVYFIWRGTAG
>Mature_462_residues
MQLGGSEGSARIRDCRHPAPPIISPCNHGRNMPSELPRRLGLLDSSAIVVGTIIGSGIFLVPNLVARSLPSAPWIIAVWI
FTGALSFFGALAYAELGAMIPATGGQYVFLREAYGPLWGFLCGWTYFFVVISAAIGWLAITFATYLGYFIPLTPALSKLV
AITLIAAITFVNYRGITLGATVQKLFTFTKVAALAILVAAAFVGPAHAVSENAAGPVTLSGFGVAMISCLLSYDGWVALS
FVAGEVRDPKRTLPLALALGVGGAIAIYVLANIAYLRVLSVGEIAATARVGALAAERTMGPTGGAFVSFSILMSIVGAIN
GWVLAAPRIYFAQARDGLFFRSFAAIHPRFQTPYVSILTFGAWSALLAITGTYETLASYAMYAAWVFYALTALAVIALRR
RQPDRPRPYRMTGYPVTLLIFAAVAFGFVINTFYATPGPAIVGTLLIGAGVPVYFIWRGTAG

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI186910308, Length=434, Percent_Identity=30.8755760368664, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI186910306, Length=434, Percent_Identity=30.8755760368664, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI186910304, Length=434, Percent_Identity=30.8755760368664, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI187423910, Length=413, Percent_Identity=30.2663438256659, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI7657591, Length=413, Percent_Identity=30.2663438256659, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI115648063, Length=434, Percent_Identity=29.7235023041475, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI115648022, Length=434, Percent_Identity=29.7235023041475, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI33286428, Length=438, Percent_Identity=31.2785388127854, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI7657683, Length=432, Percent_Identity=28.4722222222222, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI71979932, Length=434, Percent_Identity=31.5668202764977, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI9790235, Length=440, Percent_Identity=28.8636363636364, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI33286430, Length=226, Percent_Identity=30.5309734513274, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI4507047, Length=429, Percent_Identity=24.7086247086247, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI110347453, Length=402, Percent_Identity=27.1144278606965, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI258614003, Length=429, Percent_Identity=24.009324009324, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI258614005, Length=429, Percent_Identity=24.009324009324, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI258645169, Length=429, Percent_Identity=25.1748251748252, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI71999149, Length=398, Percent_Identity=22.8643216080402, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI114326544, Length=426, Percent_Identity=23.7089201877934, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI114326550, Length=426, Percent_Identity=23.7089201877934, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082250, Length=436, Percent_Identity=28.8990825688073, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI2367353, Length=385, Percent_Identity=25.974025974026, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790575, Length=326, Percent_Identity=27.9141104294479, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787890, Length=337, Percent_Identity=27.299703264095, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786602, Length=332, Percent_Identity=23.7951807228916, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082023, Length=344, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=456, Percent_Identity=31.5789473684211, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI32566699, Length=442, Percent_Identity=29.8642533936652, Blast_Score=161, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17568033, Length=469, Percent_Identity=30.0639658848614, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71982612, Length=428, Percent_Identity=26.8691588785047, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71982608, Length=428, Percent_Identity=26.8691588785047, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193208714, Length=398, Percent_Identity=30.6532663316583, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32566695, Length=399, Percent_Identity=30.5764411027569, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71990446, Length=401, Percent_Identity=26.4339152119701, Blast_Score=118, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17532491, Length=413, Percent_Identity=27.1186440677966, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71993915, Length=439, Percent_Identity=26.879271070615, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71982623, Length=279, Percent_Identity=29.0322580645161, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71995388, Length=447, Percent_Identity=25.0559284116331, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71995382, Length=447, Percent_Identity=25.0559284116331, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17533459, Length=411, Percent_Identity=26.2773722627737, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531343, Length=409, Percent_Identity=24.2053789731051, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321751, Length=438, Percent_Identity=25.5707762557078, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321492, Length=387, Percent_Identity=21.7054263565891, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331183, Length=452, Percent_Identity=32.7433628318584, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17647653, Length=452, Percent_Identity=32.7433628318584, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24664379, Length=452, Percent_Identity=32.7433628318584, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24641995, Length=414, Percent_Identity=31.1594202898551, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24641993, Length=414, Percent_Identity=31.1594202898551, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24651635, Length=437, Percent_Identity=30.8924485125858, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24651633, Length=437, Percent_Identity=30.8924485125858, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357367, Length=439, Percent_Identity=30.9794988610478, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI45550968, Length=429, Percent_Identity=30.5361305361305, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI19921172, Length=429, Percent_Identity=30.5361305361305, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24667468, Length=427, Percent_Identity=24.1217798594848, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI221512776, Length=407, Percent_Identity=22.1130221130221, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666159, Length=407, Percent_Identity=22.1130221130221, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161077963, Length=414, Percent_Identity=23.4299516908213, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48947; Mature: 48947

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLGGSEGSARIRDCRHPAPPIISPCNHGRNMPSELPRRLGLLDSSAIVVGTIIGSGIFL
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEHHHHCCCHHH
VPNLVARSLPSAPWIIAVWIFTGALSFFGALAYAELGAMIPATGGQYVFLREAYGPLWGF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCHHHHH
LCGWTYFFVVISAAIGWLAITFATYLGYFIPLTPALSKLVAITLIAAITFVNYRGITLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHH
TVQKLFTFTKVAALAILVAAAFVGPAHAVSENAAGPVTLSGFGVAMISCLLSYDGWVALS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECHHHHHHHHHHHHCCCCEEEE
FVAGEVRDPKRTLPLALALGVGGAIAIYVLANIAYLRVLSVGEIAATARVGALAAERTMG
EHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTGGAFVSFSILMSIVGAINGWVLAAPRIYFAQARDGLFFRSFAAIHPRFQTPYVSILTF
CCCCHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHH
GAWSALLAITGTYETLASYAMYAAWVFYALTALAVIALRRRQPDRPRPYRMTGYPVTLLI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHH
FAAVAFGFVINTFYATPGPAIVGTLLIGAGVPVYFIWRGTAG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure
MQLGGSEGSARIRDCRHPAPPIISPCNHGRNMPSELPRRLGLLDSSAIVVGTIIGSGIFL
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEHHHHCCCHHH
VPNLVARSLPSAPWIIAVWIFTGALSFFGALAYAELGAMIPATGGQYVFLREAYGPLWGF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCHHHHH
LCGWTYFFVVISAAIGWLAITFATYLGYFIPLTPALSKLVAITLIAAITFVNYRGITLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHH
TVQKLFTFTKVAALAILVAAAFVGPAHAVSENAAGPVTLSGFGVAMISCLLSYDGWVALS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECHHHHHHHHHHHHCCCCEEEE
FVAGEVRDPKRTLPLALALGVGGAIAIYVLANIAYLRVLSVGEIAATARVGALAAERTMG
EHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTGGAFVSFSILMSIVGAINGWVLAAPRIYFAQARDGLFFRSFAAIHPRFQTPYVSILTF
CCCCHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHH
GAWSALLAITGTYETLASYAMYAAWVFYALTALAVIALRRRQPDRPRPYRMTGYPVTLLI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHH
FAAVAFGFVINTFYATPGPAIVGTLLIGAGVPVYFIWRGTAG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]