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The map label for this gene is cph1 [H]

Identifier: 116621159

GI number: 116621159

Start: 2586821

End: 2587495

Strand: Direct

Name: cph1 [H]

Synonym: Acid_2040

Alternate gene names: 116621159

Gene position: 2586821-2587495 (Clockwise)

Preceding gene: 116621153

Following gene: 116621164

Centisome position: 25.96

GC content: 64.44

Gene sequence:

>675_bases
ATGAGGGGATTCAAATCCGATCGGGAACTCAGCGAGTTTCTGCTGAGGGCCTGCCACGATGTGAGAGCGGCGGCGCGGGC
CGTGCGCACGCATTCCGAGTTGATCCTAAAAGATGCGGCAGCGGGGAAGAGCGCCGATCTCGAAATCCGCGCGAATTTCA
TCGTGGGCGGCGCGAGCCGGATCGATGCGCTCACCAACGGTCTTGCGGCGTTTGCGATCGCGCTGCAGACTGACCCCGGC
AGCTTCCAGGTGATGCGCGTGGATGTGCTTGTGCGCACTGTGATCGCCAAGCTCGGTCCGGATCTTCGCGCCGCCGCGGC
GGTGGTGGAGTACGGCGAACTGCCGCAGGTACTGGGAAGCCCGGACCGGCTGATGCAGGTGTTCGAGCAACTGCTGCGCA
ACGCGCTGGTGCATCGCGGGGAAGATCCGCCGCGGGTCTCGATCCAGGCGGCAAAGCACGCGGAAGGCTGGCTGTTCACG
GTACGCGACAATGGTCCGGGGCTTGAGGCCGAGTCGCTGGAGAGCATTTTTCGGCCATTCGAGCGGCTGAATTCCAATGG
GGGTGCGGGTCTGGGGCTGGCGATCTGCCGTGAGATTATCCAGCGGCACGGGGGGCGGATCTGGGCGGAATCGGCACCCG
GAGGCACGACAATTTGCTTCACGCTGCCGGATTAG

Upstream 100 bases:

>100_bases
CTGTTGTGTTCTCCTGATCACGTTAGTGATCGTACGAAAGGAAGCGTAGCGCGCATAGGTTTCGCGTTACCATCACCGCG
AGGGTAGAGTTATTCCACCA

Downstream 100 bases:

>100_bases
CGTAATCGGACCTTGAAATCCCGGAAGTTAGTTTGATTGGAAGGCTAAGAAAGCCACAAACAAACTAAGTACACAGCGGC
AAGAGACACGCGAGGAGACC

Product: histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRGFKSDRELSEFLLRACHDVRAAARAVRTHSELILKDAAAGKSADLEIRANFIVGGASRIDALTNGLAAFAIALQTDPG
SFQVMRVDVLVRTVIAKLGPDLRAAAAVVEYGELPQVLGSPDRLMQVFEQLLRNALVHRGEDPPRVSIQAAKHAEGWLFT
VRDNGPGLEAESLESIFRPFERLNSNGGAGLGLAICREIIQRHGGRIWAESAPGGTTICFTLPD

Sequences:

>Translated_224_residues
MRGFKSDRELSEFLLRACHDVRAAARAVRTHSELILKDAAAGKSADLEIRANFIVGGASRIDALTNGLAAFAIALQTDPG
SFQVMRVDVLVRTVIAKLGPDLRAAAAVVEYGELPQVLGSPDRLMQVFEQLLRNALVHRGEDPPRVSIQAAKHAEGWLFT
VRDNGPGLEAESLESIFRPFERLNSNGGAGLGLAICREIIQRHGGRIWAESAPGGTTICFTLPD
>Mature_224_residues
MRGFKSDRELSEFLLRACHDVRAAARAVRTHSELILKDAAAGKSADLEIRANFIVGGASRIDALTNGLAAFAIALQTDPG
SFQVMRVDVLVRTVIAKLGPDLRAAAAVVEYGELPQVLGSPDRLMQVFEQLLRNALVHRGEDPPRVSIQAAKHAEGWLFT
VRDNGPGLEAESLESIFRPFERLNSNGGAGLGLAICREIIQRHGGRIWAESAPGGTTICFTLPD

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=215, Percent_Identity=29.3023255813954, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=113, Percent_Identity=38.0530973451327, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790436, Length=111, Percent_Identity=36.9369369369369, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87081816, Length=128, Percent_Identity=35.9375, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790300, Length=120, Percent_Identity=34.1666666666667, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=102, Percent_Identity=41.1764705882353, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 24177; Mature: 24177

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFKSDRELSEFLLRACHDVRAAARAVRTHSELILKDAAAGKSADLEIRANFIVGGASR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCHHH
IDALTNGLAAFAIALQTDPGSFQVMRVDVLVRTVIAKLGPDLRAAAAVVEYGELPQVLGS
HHHHHHHHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCC
PDRLMQVFEQLLRNALVHRGEDPPRVSIQAAKHAEGWLFTVRDNGPGLEAESLESIFRPF
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHH
ERLNSNGGAGLGLAICREIIQRHGGRIWAESAPGGTTICFTLPD
HHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCC
>Mature Secondary Structure
MRGFKSDRELSEFLLRACHDVRAAARAVRTHSELILKDAAAGKSADLEIRANFIVGGASR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCHHH
IDALTNGLAAFAIALQTDPGSFQVMRVDVLVRTVIAKLGPDLRAAAAVVEYGELPQVLGS
HHHHHHHHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCC
PDRLMQVFEQLLRNALVHRGEDPPRVSIQAAKHAEGWLFTVRDNGPGLEAESLESIFRPF
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHH
ERLNSNGGAGLGLAICREIIQRHGGRIWAESAPGGTTICFTLPD
HHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]