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The map label for this gene is fadM [H]

Identifier: 116621126

GI number: 116621126

Start: 2536336

End: 2537247

Strand: Reverse

Name: fadM [H]

Synonym: Acid_2007

Alternate gene names: 116621126

Gene position: 2537247-2536336 (Counterclockwise)

Preceding gene: 116621127

Following gene: 116621125

Centisome position: 25.46

GC content: 57.68

Gene sequence:

>912_bases
GTGGTGCGGGCCTTCTTCCTTTTCCTTTCTCGTCAAAAACAACTTCGGCGGTGGATGGAGACGTCTCCGGTAGCGCAGCG
GCTATCGAAACGCTTCGTCGCGGGCGAGACCCTGGAGCAAGCGCTTGCAGTCTCTCGCAAACTAAACAAACAGGGAATTA
CGGTGACGCTGGATCACCTCGGGGAGAGCGTCACGAGCTTGGCCGAGGCGCGGGAGGCGCGCGACGTATATCGGCGTACA
CTGGATGCGATCCATGCCGGAGACATCCAGGGAAACGTCTCGCTGAAACTGACGCAGTTCGGCCTGGACCTCAGCTACGA
AGAATGCCTGGCTAACGTAGAGCAACTGGTGCGGCGGGCCGCCGAACTGGGAAGCTTCGTGCGCGTGGATATGGAATCCA
GCGAGTATGTGGATCGCACGCTCGATTTAGTCCGAACGCTGCACGCGCGGCACGGCGCAGTCGGAGTGGTGATTCAGTCC
TACCTCTATCGGAGTAAGGACGATATCGCTAAGCTGTGCGCGGAGAAAATTCGAGTCCGGCTGTGCAAAGGCGCGTACCT
GGAGCCTGCATCGCTGGCGTTTCCGCAGAAATCGGATGTGGACCGCAGCTATGTGGAACTAACGCAGAAACTGCTGACAT
ATGGGGTGTATCCCGCAATCGCGACGCATGACGAGGCAATGATCGGACAGACGAAACAGTTCGTTTCGTCCAAAGGAATC
GGGCGCGAGTGCTTTGAATTTCAGATGCTGTACGGAATCCGCGCAGATTTGCAACGGCAACTGGTGGCCGACGGCTACCG
GCTGCGGCTCTATGTCCCATTTGGGAAGGCGTGGTATCCCTACTATATGCGCCGGCTGGCGGAGCGTCCCGCGAACGTGC
TGTTTATTTTACGGAATCTGTTTAGGACTTAG

Upstream 100 bases:

>100_bases
TCTCGGAAGTCTAGCAGAATCATCGACGGAGCGTTAGGGGCCGGCGGTTTGCGCCGATGACGGAAGGACACAACCACCCG
GTGCAGGGTGTTAGCCTATC

Downstream 100 bases:

>100_bases
GAATTTAGATCGCTCCCTGACGGTCGCGGTTCGCGGTGACGGTGATGAGCTATGGTGGAGTGGTGCGCGTGGGCCCCAGG
CCGGTTTGTCCCACTAGTCC

Product: L-proline dehydrogenase

Products: NA

Alternate protein names: PRODH 1; Proline oxidase 1 [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MVRAFFLFLSRQKQLRRWMETSPVAQRLSKRFVAGETLEQALAVSRKLNKQGITVTLDHLGESVTSLAEAREARDVYRRT
LDAIHAGDIQGNVSLKLTQFGLDLSYEECLANVEQLVRRAAELGSFVRVDMESSEYVDRTLDLVRTLHARHGAVGVVIQS
YLYRSKDDIAKLCAEKIRVRLCKGAYLEPASLAFPQKSDVDRSYVELTQKLLTYGVYPAIATHDEAMIGQTKQFVSSKGI
GRECFEFQMLYGIRADLQRQLVADGYRLRLYVPFGKAWYPYYMRRLAERPANVLFILRNLFRT

Sequences:

>Translated_303_residues
MVRAFFLFLSRQKQLRRWMETSPVAQRLSKRFVAGETLEQALAVSRKLNKQGITVTLDHLGESVTSLAEAREARDVYRRT
LDAIHAGDIQGNVSLKLTQFGLDLSYEECLANVEQLVRRAAELGSFVRVDMESSEYVDRTLDLVRTLHARHGAVGVVIQS
YLYRSKDDIAKLCAEKIRVRLCKGAYLEPASLAFPQKSDVDRSYVELTQKLLTYGVYPAIATHDEAMIGQTKQFVSSKGI
GRECFEFQMLYGIRADLQRQLVADGYRLRLYVPFGKAWYPYYMRRLAERPANVLFILRNLFRT
>Mature_303_residues
MVRAFFLFLSRQKQLRRWMETSPVAQRLSKRFVAGETLEQALAVSRKLNKQGITVTLDHLGESVTSLAEAREARDVYRRT
LDAIHAGDIQGNVSLKLTQFGLDLSYEECLANVEQLVRRAAELGSFVRVDMESSEYVDRTLDLVRTLHARHGAVGVVIQS
YLYRSKDDIAKLCAEKIRVRLCKGAYLEPASLAFPQKSDVDRSYVELTQKLLTYGVYPAIATHDEAMIGQTKQFVSSKGI
GRECFEFQMLYGIRADLQRQLVADGYRLRLYVPFGKAWYPYYMRRLAERPANVLFILRNLFRT

Specific function: Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C) [H]

COG id: COG0506

COG function: function code E; Proline dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1787250, Length=316, Percent_Identity=28.4810126582279, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015590
- InterPro:   IPR002872
- InterPro:   IPR008219 [H]

Pfam domain/function: PF01619 Pro_dh [H]

EC number: =1.5.99.8 [H]

Molecular weight: Translated: 34720; Mature: 34720

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRAFFLFLSRQKQLRRWMETSPVAQRLSKRFVAGETLEQALAVSRKLNKQGITVTLDHL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
GESVTSLAEAREARDVYRRTLDAIHAGDIQGNVSLKLTQFGLDLSYEECLANVEQLVRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
AELGSFVRVDMESSEYVDRTLDLVRTLHARHGAVGVVIQSYLYRSKDDIAKLCAEKIRVR
HHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LCKGAYLEPASLAFPQKSDVDRSYVELTQKLLTYGVYPAIATHDEAMIGQTKQFVSSKGI
HHCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCC
GRECFEFQMLYGIRADLQRQLVADGYRLRLYVPFGKAWYPYYMRRLAERPANVLFILRNL
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHH
FRT
HCC
>Mature Secondary Structure
MVRAFFLFLSRQKQLRRWMETSPVAQRLSKRFVAGETLEQALAVSRKLNKQGITVTLDHL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
GESVTSLAEAREARDVYRRTLDAIHAGDIQGNVSLKLTQFGLDLSYEECLANVEQLVRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
AELGSFVRVDMESSEYVDRTLDLVRTLHARHGAVGVVIQSYLYRSKDDIAKLCAEKIRVR
HHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LCKGAYLEPASLAFPQKSDVDRSYVELTQKLLTYGVYPAIATHDEAMIGQTKQFVSSKGI
HHCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCC
GRECFEFQMLYGIRADLQRQLVADGYRLRLYVPFGKAWYPYYMRRLAERPANVLFILRNL
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHH
FRT
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA