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The map label for this gene is licH [H]

Identifier: 116621044

GI number: 116621044

Start: 2390202

End: 2391566

Strand: Reverse

Name: licH [H]

Synonym: Acid_1925

Alternate gene names: 116621044

Gene position: 2391566-2390202 (Counterclockwise)

Preceding gene: 116621045

Following gene: 116621043

Centisome position: 24.0

GC content: 61.98

Gene sequence:

>1365_bases
ATGCGAAAAGTAACCATTATCGGAGGCGGCGGAGTGCGGACGCCGCTGGTCATCTATGGCCTGGCGCAAGCACAACAATT
GCTCCAGGTGGATCGGCTCACGCTGTACGACGTGGACACACAGCGCGTCGAAACGATCGCCCGGCTCGGACGTGAAATTC
TGCGACGATCATCGAACCCAGCTTTCGAGATTCGCGTCTCCTCGCGCCTCGAGGAAGCCGCCGAAGGCGCGGATTTCGTG
CTGAACAGCATCCGGGTCGGTGGGATTGCCGCGCGCGCGCGCGATGAACGGATCGCCATCGAACATGACTTGGCAGGGCA
GGAAACAACCGGACCCGCCGGCGTTGCGATGGCCCTGCGGACCGTTCCGGTCACGCTGCAGCACGCTCGCATCGTGGAGC
GCGCGGCGCCCGCGGCGTGGTTCATCAACTTTACGAACCCCGCCGGGCTGATTACGCAGGCGCTCCAACAGCACACTGGC
TTGCGGGTCATCGGCATCTGCGACACACCCATCGAACTCTTTCACAAAATTGCGGAGGCGGCCGGCGAAGCGACGGCCGA
GATGGAGTTCGATTACGCAGGCCTGAATCACCTGGGCTGGGTCCGCCGCGTCCTGCTTCGCGGCGGTGATATCACGGAGC
GCCTTTTGGCCGACTCGGAGTTCTTGCGCCGCGTCTACCCCACCGGACTCTTTGACCCCGCGTTGATCCAGGCGCTCCGC
CTCATTCCGACGGAGTATCTGTTTTTTTGCTATAGCCAGCGGAAGGCGCACGCGAATCAGCTGCGTGCGGGAGCGAGCCG
CGGGGAGGAAATCGGACGCATGAACGAAGCCCTCTTCCATCGCCTCGCCAGCGAGGACGCCGCCACTGGTCTTTCGGTTT
ATCGCGCCTATCTGCTGCAGCGGAACGCTTCATACATGAAGCTCGAGGCGCAGGCGGAGTCCGCGTTCGAGGTTGCGAAA
GAGGACTACGACCCGTTCGAGACCGCGACTGGGTACCACCGGATTGCACTCGACGTCATGACCAGTCTGGTCTCCGGTCG
CAGCCGCAGCGTAGTTGTGAATGTTAGGAATAACGGGGCCATTGAGGACCTCGAGCCGGATGACGTAGTCGAAGTGCCGT
GCGATGTCGATCGCGATGGGGCTCGACCGCGGAGGACGGGCCGGCTCCCGGATTCTATTCGTGGTCTTGTTCAGGCCGTG
AAGGCCTATGAGCGCACGGCTATCCAAGCTGCGATCACCGGCTCGAGCTCGCTCGCGCAACTTGCGATGCTCGAATACCC
GATTATCGGCCAGTGGGAATTGGCAGGCAGTCTCAAAGAGGCGCTGATCAACGGGGATCCCGAACACTTGAGCTACTTAA
GGTAA

Upstream 100 bases:

>100_bases
GGTCTGCCAACATCTGTGGTGCGCTTTCGACCGGGTCGTATGGCGGCGTCGCGGGACTTCCGGACAGTGCGCGGTTGAAT
GAACTATTGAGAGCACGCGA

Downstream 100 bases:

>100_bases
TCGACTAAGTTGGCGTTGATTTCTCGTTACGAATACGAATGGTGACCGCCCAGCACTCTGGAAAGTGTCATCGCGTGGGC
CAACACTGCGAAGGTGCGCC

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MRKVTIIGGGGVRTPLVIYGLAQAQQLLQVDRLTLYDVDTQRVETIARLGREILRRSSNPAFEIRVSSRLEEAAEGADFV
LNSIRVGGIAARARDERIAIEHDLAGQETTGPAGVAMALRTVPVTLQHARIVERAAPAAWFINFTNPAGLITQALQQHTG
LRVIGICDTPIELFHKIAEAAGEATAEMEFDYAGLNHLGWVRRVLLRGGDITERLLADSEFLRRVYPTGLFDPALIQALR
LIPTEYLFFCYSQRKAHANQLRAGASRGEEIGRMNEALFHRLASEDAATGLSVYRAYLLQRNASYMKLEAQAESAFEVAK
EDYDPFETATGYHRIALDVMTSLVSGRSRSVVVNVRNNGAIEDLEPDDVVEVPCDVDRDGARPRRTGRLPDSIRGLVQAV
KAYERTAIQAAITGSSSLAQLAMLEYPIIGQWELAGSLKEALINGDPEHLSYLR

Sequences:

>Translated_454_residues
MRKVTIIGGGGVRTPLVIYGLAQAQQLLQVDRLTLYDVDTQRVETIARLGREILRRSSNPAFEIRVSSRLEEAAEGADFV
LNSIRVGGIAARARDERIAIEHDLAGQETTGPAGVAMALRTVPVTLQHARIVERAAPAAWFINFTNPAGLITQALQQHTG
LRVIGICDTPIELFHKIAEAAGEATAEMEFDYAGLNHLGWVRRVLLRGGDITERLLADSEFLRRVYPTGLFDPALIQALR
LIPTEYLFFCYSQRKAHANQLRAGASRGEEIGRMNEALFHRLASEDAATGLSVYRAYLLQRNASYMKLEAQAESAFEVAK
EDYDPFETATGYHRIALDVMTSLVSGRSRSVVVNVRNNGAIEDLEPDDVVEVPCDVDRDGARPRRTGRLPDSIRGLVQAV
KAYERTAIQAAITGSSSLAQLAMLEYPIIGQWELAGSLKEALINGDPEHLSYLR
>Mature_454_residues
MRKVTIIGGGGVRTPLVIYGLAQAQQLLQVDRLTLYDVDTQRVETIARLGREILRRSSNPAFEIRVSSRLEEAAEGADFV
LNSIRVGGIAARARDERIAIEHDLAGQETTGPAGVAMALRTVPVTLQHARIVERAAPAAWFINFTNPAGLITQALQQHTG
LRVIGICDTPIELFHKIAEAAGEATAEMEFDYAGLNHLGWVRRVLLRGGDITERLLADSEFLRRVYPTGLFDPALIQALR
LIPTEYLFFCYSQRKAHANQLRAGASRGEEIGRMNEALFHRLASEDAATGLSVYRAYLLQRNASYMKLEAQAESAFEVAK
EDYDPFETATGYHRIALDVMTSLVSGRSRSVVVNVRNNGAIEDLEPDDVVEVPCDVDRDGARPRRTGRLPDSIRGLVQAV
KAYERTAIQAAITGSSSLAQLAMLEYPIIGQWELAGSLKEALINGDPEHLSYLR

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=441, Percent_Identity=30.1587301587302, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1790560, Length=418, Percent_Identity=24.4019138755981, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 49989; Mature: 49989

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVTIIGGGGVRTPLVIYGLAQAQQLLQVDRLTLYDVDTQRVETIARLGREILRRSSNP
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCCCC
AFEIRVSSRLEEAAEGADFVLNSIRVGGIAARARDERIAIEHDLAGQETTGPAGVAMALR
EEEEEEHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCCCCHHHHHHHH
TVPVTLQHARIVERAAPAAWFINFTNPAGLITQALQQHTGLRVIGICDTPIELFHKIAEA
HHCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
AGEATAEMEFDYAGLNHLGWVRRVLLRGGDITERLLADSEFLRRVYPTGLFDPALIQALR
HCCCHHEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LIPTEYLFFCYSQRKAHANQLRAGASRGEEIGRMNEALFHRLASEDAATGLSVYRAYLLQ
HCCHHHHHHHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNASYMKLEAQAESAFEVAKEDYDPFETATGYHRIALDVMTSLVSGRSRSVVVNVRNNGA
CCCCCEEEEHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
IEDLEPDDVVEVPCDVDRDGARPRRTGRLPDSIRGLVQAVKAYERTAIQAAITGSSSLAQ
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
LAMLEYPIIGQWELAGSLKEALINGDPEHLSYLR
HHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MRKVTIIGGGGVRTPLVIYGLAQAQQLLQVDRLTLYDVDTQRVETIARLGREILRRSSNP
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCCCC
AFEIRVSSRLEEAAEGADFVLNSIRVGGIAARARDERIAIEHDLAGQETTGPAGVAMALR
EEEEEEHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCCCCHHHHHHHH
TVPVTLQHARIVERAAPAAWFINFTNPAGLITQALQQHTGLRVIGICDTPIELFHKIAEA
HHCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
AGEATAEMEFDYAGLNHLGWVRRVLLRGGDITERLLADSEFLRRVYPTGLFDPALIQALR
HCCCHHEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LIPTEYLFFCYSQRKAHANQLRAGASRGEEIGRMNEALFHRLASEDAATGLSVYRAYLLQ
HCCHHHHHHHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNASYMKLEAQAESAFEVAKEDYDPFETATGYHRIALDVMTSLVSGRSRSVVVNVRNNGA
CCCCCEEEEHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
IEDLEPDDVVEVPCDVDRDGARPRRTGRLPDSIRGLVQAVKAYERTAIQAAITGSSSLAQ
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
LAMLEYPIIGQWELAGSLKEALINGDPEHLSYLR
HHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]