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The map label for this gene is menC [H]

Identifier: 116620966

GI number: 116620966

Start: 2298549

End: 2299658

Strand: Direct

Name: menC [H]

Synonym: Acid_1847

Alternate gene names: 116620966

Gene position: 2298549-2299658 (Clockwise)

Preceding gene: 116620965

Following gene: 116620967

Centisome position: 23.06

GC content: 63.42

Gene sequence:

>1110_bases
ATGAAACTCGAACGCATCGTGTTGCACCAGATCCGCATGCCGCTGGTGCACTTCTTTGAGACCAGCTTTTCGCGTACGTA
CAGCCGCGACATCATTCTGGTGGAGGTCACCAGCGAAGGCGTCACCGGTTGGGGCGAAGTCACCGCCGGCGAGAACCCGT
TCTACAACGAGGAGTGGACCGATTCGGCCTGGCTGATTCTGCGCAACTACGCCGGACCCCGCGTGCTCGGACGCGACCTC
ACGTCGGCCGAGGATGTCGCTCCGCTTACCGCGCACATCCGCGGGCATAACATGGCGCGAGCCGGACTCGAGGTGGCGGT
ATGGGATCTGGAGTCGCGAATCAACTGCGTGCCGCTGTGGAAGCAGATCGGCGGCGGCGCCCATCGCGAGATCCCCTGCG
GTGTCTCGATCGGCATTCAGGATTCGGTGGAGCAGTTGTTCGAGAAGATCGAGACCGAGCTCGCCGCAGGCTACCAGCGC
ATCAAGATGAAGATCAAGCCGGGCTGGGACGTCGATGTGGTCGGCAGGGTGCGCGAGCGCTTCCCCTCCATCAAGCTCAT
GGCCGACGCCAACTCCGCCTACACGCTGGCCGATATCGACCACTTGAAGAAGCTCGACGATTTCTACCTGATGATGATCG
AGCAGCCGCTCAGCCACGACGACATCATCGATCACGCCGTGCTGCAATCGAAACTGCAGACGCCCATCTGCCTCGACGAA
TGCCTGCGCAACGCGCACCAGGCCGAGCAGGCCATCCGCATGCGGGCCTGCGGCATCATCAATATCAAGCTGGGACGCGT
CGGCGGCTTCCGCGAGGCCAAACGCCTGCACGACGTGGCGCAGGACGCGGGAATTCCGGTCTGGTGCGGCGGCATGCTGG
AGGCCGGAATCGGGCGCGCGCACAACGTCGCCCTCGCCAGCCTGCCGAATTTCGTCCTGCCCGGCGACGTTTCGGCAAGC
AAGCGCTATTGGAAGCAGGACATCATCCGGCCGGCAGTGGAGACCACGGCGCGCGGGACCATCGAACTCCGCGACGAACC
TGGCTTCGGCTACGCGCTCGACCCCGATTATATTCGCAGCATCACGGTCCGCGAAGAGGTTGTCGCGTAA

Upstream 100 bases:

>100_bases
AAAACGCGCACCGATTCATCGACGCCTTCGCGCGCGGACTCGCCGTCACCGGCTTTGAGCGCAGCGATACCGAAGGCGCC
TACCTCCTGGAGCCGTGGCA

Downstream 100 bases:

>100_bases
GTGCGTTGTTTCAGAAGTTCACCCACGTATCGGGGGAGGACCCTCCCTTACGGTCGGGGCTCCGAACGGAGCCGCGTGCG
TCAGCAAGCGTCTGCTCGAT

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKLERIVLHQIRMPLVHFFETSFSRTYSRDIILVEVTSEGVTGWGEVTAGENPFYNEEWTDSAWLILRNYAGPRVLGRDL
TSAEDVAPLTAHIRGHNMARAGLEVAVWDLESRINCVPLWKQIGGGAHREIPCGVSIGIQDSVEQLFEKIETELAAGYQR
IKMKIKPGWDVDVVGRVRERFPSIKLMADANSAYTLADIDHLKKLDDFYLMMIEQPLSHDDIIDHAVLQSKLQTPICLDE
CLRNAHQAEQAIRMRACGIINIKLGRVGGFREAKRLHDVAQDAGIPVWCGGMLEAGIGRAHNVALASLPNFVLPGDVSAS
KRYWKQDIIRPAVETTARGTIELRDEPGFGYALDPDYIRSITVREEVVA

Sequences:

>Translated_369_residues
MKLERIVLHQIRMPLVHFFETSFSRTYSRDIILVEVTSEGVTGWGEVTAGENPFYNEEWTDSAWLILRNYAGPRVLGRDL
TSAEDVAPLTAHIRGHNMARAGLEVAVWDLESRINCVPLWKQIGGGAHREIPCGVSIGIQDSVEQLFEKIETELAAGYQR
IKMKIKPGWDVDVVGRVRERFPSIKLMADANSAYTLADIDHLKKLDDFYLMMIEQPLSHDDIIDHAVLQSKLQTPICLDE
CLRNAHQAEQAIRMRACGIINIKLGRVGGFREAKRLHDVAQDAGIPVWCGGMLEAGIGRAHNVALASLPNFVLPGDVSAS
KRYWKQDIIRPAVETTARGTIELRDEPGFGYALDPDYIRSITVREEVVA
>Mature_369_residues
MKLERIVLHQIRMPLVHFFETSFSRTYSRDIILVEVTSEGVTGWGEVTAGENPFYNEEWTDSAWLILRNYAGPRVLGRDL
TSAEDVAPLTAHIRGHNMARAGLEVAVWDLESRINCVPLWKQIGGGAHREIPCGVSIGIQDSVEQLFEKIETELAAGYQR
IKMKIKPGWDVDVVGRVRERFPSIKLMADANSAYTLADIDHLKKLDDFYLMMIEQPLSHDDIIDHAVLQSKLQTPICLDE
CLRNAHQAEQAIRMRACGIINIKLGRVGGFREAKRLHDVAQDAGIPVWCGGMLEAGIGRAHNVALASLPNFVLPGDVSAS
KRYWKQDIIRPAVETTARGTIELRDEPGFGYALDPDYIRSITVREEVVA

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 41307; Mature: 41307

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLERIVLHQIRMPLVHFFETSFSRTYSRDIILVEVTSEGVTGWGEVTAGENPFYNEEWT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
DSAWLILRNYAGPRVLGRDLTSAEDVAPLTAHIRGHNMARAGLEVAVWDLESRINCVPLW
CCEEEEEECCCCCHHHCCCCCCCHHCCHHHHHHCCCCHHHCCCEEEEEECCCCCCEEEHH
KQIGGGAHREIPCGVSIGIQDSVEQLFEKIETELAAGYQRIKMKIKPGWDVDVVGRVRER
HHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHH
FPSIKLMADANSAYTLADIDHLKKLDDFYLMMIEQPLSHDDIIDHAVLQSKLQTPICLDE
CCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHH
CLRNAHQAEQAIRMRACGIINIKLGRVGGFREAKRLHDVAQDAGIPVWCGGMLEAGIGRA
HHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECHHHHHCCCCH
HNVALASLPNFVLPGDVSASKRYWKQDIIRPAVETTARGTIELRDEPGFGYALDPDYIRS
HCCHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
ITVREEVVA
HHHHHHHCC
>Mature Secondary Structure
MKLERIVLHQIRMPLVHFFETSFSRTYSRDIILVEVTSEGVTGWGEVTAGENPFYNEEWT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
DSAWLILRNYAGPRVLGRDLTSAEDVAPLTAHIRGHNMARAGLEVAVWDLESRINCVPLW
CCEEEEEECCCCCHHHCCCCCCCHHCCHHHHHHCCCCHHHCCCEEEEEECCCCCCEEEHH
KQIGGGAHREIPCGVSIGIQDSVEQLFEKIETELAAGYQRIKMKIKPGWDVDVVGRVRER
HHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHH
FPSIKLMADANSAYTLADIDHLKKLDDFYLMMIEQPLSHDDIIDHAVLQSKLQTPICLDE
CCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHH
CLRNAHQAEQAIRMRACGIINIKLGRVGGFREAKRLHDVAQDAGIPVWCGGMLEAGIGRA
HHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECHHHHHCCCCH
HNVALASLPNFVLPGDVSASKRYWKQDIIRPAVETTARGTIELRDEPGFGYALDPDYIRS
HCCHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
ITVREEVVA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]