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The map label for this gene is macB1 [H]

Identifier: 116620943

GI number: 116620943

Start: 2269919

End: 2272342

Strand: Reverse

Name: macB1 [H]

Synonym: Acid_1824

Alternate gene names: 116620943

Gene position: 2272342-2269919 (Counterclockwise)

Preceding gene: 116620944

Following gene: 116620942

Centisome position: 22.8

GC content: 65.76

Gene sequence:

>2424_bases
ATGAGCCTGGCCGGTAATCTCAAGTTCACGCTGCGCATCCTGCGCCGCAACCCCGCGCTGGCGATCTCCGCGATTTTGGC
GACCGGCCTCGGCATCGGCGCTACCAGCGCGATGTTCAGTATCGCGGACGGCATTCTGCTGCATCCGCTTCCCTTCCCGA
AGAGCGACCGCCTGGTGAACGTGTGGGAGACGGCGGCCGCGCGCAATATTCCGCGGATGGTGGTGGCGCCGGGGAACTAC
TACGATTGGCGCGCGCAGAGCCATTCTTTCTCGGCGCTCGGAGCTTTCCAGCAGTCCACCTTCAACCTGGCGACCGGGGA
TGCGGAGCCCGAGCGGCTTTTGGGAGCGATCGCCGACCCGGGATTTTTCGCGGCGCTCGGAGTTGCGCCGCTGTTGGGGC
GGGTGTGCACGGAAGCAGAGAATCTGCCGGGAGGCAACGCGGTCGTCATCTTGAGCTACGCGCTCTGGCAGCAGCGATTC
GGGGCTGACCGGGGTATTTTGGGGCGTACGCTGGAGCTCAACGGACGGACGCGCACCGTGATCGGCGTGATGCCGCAAGG
TTTCGATTTCCCTGCGCAGTCCACGATATGGTCGCCGCTGGAACTGGATCCACCTACTATGGCCCGCCGGGATTTTCACC
GGCTGCGCGTGATCGGCCGGCTTAAGGACGGGGTTTCGCTGGAACAGGCACGGGCGAATTTTCAGACGATCGCGGCGGGG
CTGGCGGCGCAGTATCCCGATTTCAACGCCGGCGAGACGACAACGCTGAATCCGATGCTCGAAGATCTTGTGGGAACGGT
CCGCCCCGCACTGCTGGTGCTGCTGGGCGCAGTGGTTGCGGTCCTGCTGATCGCGTGCGCCAATGTCGCCAATCTTCTGC
TGGCGAAGGCTTCGGGACGGCAGAGGGAGATCGCGATCCGCACGTCGATGGGCGCGAGCCGCGGCGCGATCCTGGGCCAG
ATGCTGACGGAGAGCACGGTGCTCGCGGTGCTCGGCGGCATCACGGGATTAGTGCTGGCGAAGCTGGCGCTGCGCGGCCT
GATCTCGCTGGCGCCGGCAAGTATTCCGCGGCTCGCCGAGATCACGCTGAATGGCCGCGTGGTCGGTCTGGGTCTGGCGC
TTTCGCTGGCTACCGGAATTCTTTTTGGGCTGGCCCCGGCGTGGTTTGCGGCAAGAGTGAACGTCAACGGCATGCTGAAA
GAGGGGATGCGCGGTTCGAGCGCGCGCAATCCGCTGCGCAGCGTGCTGGTGGCGGCGCAGGTGGCGATCGCGCTGGTGCT
GCTGTCGGGCGCCGGATTATTGATCCGCAGCTTCTATGAGGTGGCCAGCGTGGATGCCGGCTTCCAGCCGGAGCACATGA
TGACGATGCAGCTGGCTCCGGCGATCACGCGCTATCGCGGTCATCCGGAGCTGCAAATTCAACTGGCGCGCGGAATTCTG
GAGAAGGTGTCGGCGATCCGCGGCGTGCGCAGCGCCGCCGTTTCGACAGCCGTTCCGCTGCTGGGGACCCCGAACTACAT
CATGCGCTTCGAAGGCCGCGCTCCGGTCACGCCGAGCCAATCTCCGCTCACCTCATATTTCGGAGTGACACCCGCGTTTT
TCGAGACGATGGGGATGCGGCTGCTTCGCGGAAGGCTGCTGAACGCGCGCGACGTGCAGGGCGCGCCGCTGGTGGTGGTG
GTCAACCAGACGCTGGTGGACCGGTACTTTCCGAAGCAGGACCCGATCGGCAAGCGGCTGGAGATCGGCTTCAGCGATCC
GCCGAACTGGCGCGAGATCGTCGGCGTGGTCGCCGATGTGAAGACGGCGGGGCTGGACCAGCAGACTCCGGTGCAGGTTT
ACACGGCGTACCTGCAGACGCCTTCGTTCCCGAGCAGCATGATCTCGCCGATCACCGTGATGACGCGGACCGAGGGCGAC
CCGGGGCTGCTGGGCGCGGCGATGCATGCGGCGATTCTGGCGGTGGACCGCTCGCAGCCGGTATATGCGATTCAGCCGAT
GACGGACATCGTGGCGCAATCGATCGCGCAGCGGCGGCTGTCACTGATCCTGCTGGCGTTCTTCGCGGCGTCGGCGATGC
TGCTGGCGGCGATCGGCGTGTATGGAGTCATGTCGTTCGTGGTGGCGCAGCGCACGAGCGAGATTGGCATCCGGATGGCG
CTTGGAGCGCAGGCCGGGCAAGTCGCGTGGCACGTGCAGCGGCAGGGGATGACGCTGGTGATAGCGGGCCTGGTGATCGG
CACGGCGGGAGCGCTGGTGCTGACGCGATATCTGAGCACGCTGCTATTCCGGGTTAATCCGCGGGATCCGGTTATTCTCG
GCACGGCGGCGATGAGCTTGGTGGCGGTGTCGATTGTGGCTTGCTGGCTTCCGGCGCGGCGTGCGTCGCGCGTGGATCCG
CTGACCGCGCTGCGGAATGAGTGA

Upstream 100 bases:

>100_bases
CTGGTTACCGACCTGACCCGCCGCGGAGTGATCGCGGCATATCGCGCGATTTAGGATGCGTTCGTGACACTCGGCGGGCA
GGCGACGTCTAACATGAATC

Downstream 100 bases:

>100_bases
CGCGAACAACGAGCCGCGACCGTGAGGGCGCGATACGGCGGGTAGGCAAGTTACACTGACCTTTCGGTCAAATATGAGAT
TCCGCGGAATCGTTCTGGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MSLAGNLKFTLRILRRNPALAISAILATGLGIGATSAMFSIADGILLHPLPFPKSDRLVNVWETAAARNIPRMVVAPGNY
YDWRAQSHSFSALGAFQQSTFNLATGDAEPERLLGAIADPGFFAALGVAPLLGRVCTEAENLPGGNAVVILSYALWQQRF
GADRGILGRTLELNGRTRTVIGVMPQGFDFPAQSTIWSPLELDPPTMARRDFHRLRVIGRLKDGVSLEQARANFQTIAAG
LAAQYPDFNAGETTTLNPMLEDLVGTVRPALLVLLGAVVAVLLIACANVANLLLAKASGRQREIAIRTSMGASRGAILGQ
MLTESTVLAVLGGITGLVLAKLALRGLISLAPASIPRLAEITLNGRVVGLGLALSLATGILFGLAPAWFAARVNVNGMLK
EGMRGSSARNPLRSVLVAAQVAIALVLLSGAGLLIRSFYEVASVDAGFQPEHMMTMQLAPAITRYRGHPELQIQLARGIL
EKVSAIRGVRSAAVSTAVPLLGTPNYIMRFEGRAPVTPSQSPLTSYFGVTPAFFETMGMRLLRGRLLNARDVQGAPLVVV
VNQTLVDRYFPKQDPIGKRLEIGFSDPPNWREIVGVVADVKTAGLDQQTPVQVYTAYLQTPSFPSSMISPITVMTRTEGD
PGLLGAAMHAAILAVDRSQPVYAIQPMTDIVAQSIAQRRLSLILLAFFAASAMLLAAIGVYGVMSFVVAQRTSEIGIRMA
LGAQAGQVAWHVQRQGMTLVIAGLVIGTAGALVLTRYLSTLLFRVNPRDPVILGTAAMSLVAVSIVACWLPARRASRVDP
LTALRNE

Sequences:

>Translated_807_residues
MSLAGNLKFTLRILRRNPALAISAILATGLGIGATSAMFSIADGILLHPLPFPKSDRLVNVWETAAARNIPRMVVAPGNY
YDWRAQSHSFSALGAFQQSTFNLATGDAEPERLLGAIADPGFFAALGVAPLLGRVCTEAENLPGGNAVVILSYALWQQRF
GADRGILGRTLELNGRTRTVIGVMPQGFDFPAQSTIWSPLELDPPTMARRDFHRLRVIGRLKDGVSLEQARANFQTIAAG
LAAQYPDFNAGETTTLNPMLEDLVGTVRPALLVLLGAVVAVLLIACANVANLLLAKASGRQREIAIRTSMGASRGAILGQ
MLTESTVLAVLGGITGLVLAKLALRGLISLAPASIPRLAEITLNGRVVGLGLALSLATGILFGLAPAWFAARVNVNGMLK
EGMRGSSARNPLRSVLVAAQVAIALVLLSGAGLLIRSFYEVASVDAGFQPEHMMTMQLAPAITRYRGHPELQIQLARGIL
EKVSAIRGVRSAAVSTAVPLLGTPNYIMRFEGRAPVTPSQSPLTSYFGVTPAFFETMGMRLLRGRLLNARDVQGAPLVVV
VNQTLVDRYFPKQDPIGKRLEIGFSDPPNWREIVGVVADVKTAGLDQQTPVQVYTAYLQTPSFPSSMISPITVMTRTEGD
PGLLGAAMHAAILAVDRSQPVYAIQPMTDIVAQSIAQRRLSLILLAFFAASAMLLAAIGVYGVMSFVVAQRTSEIGIRMA
LGAQAGQVAWHVQRQGMTLVIAGLVIGTAGALVLTRYLSTLLFRVNPRDPVILGTAAMSLVAVSIVACWLPARRASRVDP
LTALRNE
>Mature_806_residues
SLAGNLKFTLRILRRNPALAISAILATGLGIGATSAMFSIADGILLHPLPFPKSDRLVNVWETAAARNIPRMVVAPGNYY
DWRAQSHSFSALGAFQQSTFNLATGDAEPERLLGAIADPGFFAALGVAPLLGRVCTEAENLPGGNAVVILSYALWQQRFG
ADRGILGRTLELNGRTRTVIGVMPQGFDFPAQSTIWSPLELDPPTMARRDFHRLRVIGRLKDGVSLEQARANFQTIAAGL
AAQYPDFNAGETTTLNPMLEDLVGTVRPALLVLLGAVVAVLLIACANVANLLLAKASGRQREIAIRTSMGASRGAILGQM
LTESTVLAVLGGITGLVLAKLALRGLISLAPASIPRLAEITLNGRVVGLGLALSLATGILFGLAPAWFAARVNVNGMLKE
GMRGSSARNPLRSVLVAAQVAIALVLLSGAGLLIRSFYEVASVDAGFQPEHMMTMQLAPAITRYRGHPELQIQLARGILE
KVSAIRGVRSAAVSTAVPLLGTPNYIMRFEGRAPVTPSQSPLTSYFGVTPAFFETMGMRLLRGRLLNARDVQGAPLVVVV
NQTLVDRYFPKQDPIGKRLEIGFSDPPNWREIVGVVADVKTAGLDQQTPVQVYTAYLQTPSFPSSMISPITVMTRTEGDP
GLLGAAMHAAILAVDRSQPVYAIQPMTDIVAQSIAQRRLSLILLAFFAASAMLLAAIGVYGVMSFVVAQRTSEIGIRMAL
GAQAGQVAWHVQRQGMTLVIAGLVIGTAGALVLTRYLSTLLFRVNPRDPVILGTAAMSLVAVSIVACWLPARRASRVDPL
TALRNE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=285, Percent_Identity=25.9649122807018, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 85866; Mature: 85735

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAGNLKFTLRILRRNPALAISAILATGLGIGATSAMFSIADGILLHPLPFPKSDRLVN
CCCCCCHHEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCCCCCCEEE
VWETAAARNIPRMVVAPGNYYDWRAQSHSFSALGAFQQSTFNLATGDAEPERLLGAIADP
HHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHCCC
GFFAALGVAPLLGRVCTEAENLPGGNAVVILSYALWQQRFGADRGILGRTLELNGRTRTV
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCEEEECCCEEEE
IGVMPQGFDFPAQSTIWSPLELDPPTMARRDFHRLRVIGRLKDGVSLEQARANFQTIAAG
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LAAQYPDFNAGETTTLNPMLEDLVGTVRPALLVLLGAVVAVLLIACANVANLLLAKASGR
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QREIAIRTSMGASRGAILGQMLTESTVLAVLGGITGLVLAKLALRGLISLAPASIPRLAE
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
ITLNGRVVGLGLALSLATGILFGLAPAWFAARVNVNGMLKEGMRGSSARNPLRSVLVAAQ
EEECCEEEEHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCCHHHHHHHHHHH
VAIALVLLSGAGLLIRSFYEVASVDAGFQPEHMMTMQLAPAITRYRGHPELQIQLARGIL
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
EKVSAIRGVRSAAVSTAVPLLGTPNYIMRFEGRAPVTPSQSPLTSYFGVTPAFFETMGMR
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
LLRGRLLNARDVQGAPLVVVVNQTLVDRYFPKQDPIGKRLEIGFSDPPNWREIVGVVADV
HHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
KTAGLDQQTPVQVYTAYLQTPSFPSSMISPITVMTRTEGDPGLLGAAMHAAILAVDRSQP
HHCCCCCCCCHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHEECCCCC
VYAIQPMTDIVAQSIAQRRLSLILLAFFAASAMLLAAIGVYGVMSFVVAQRTSEIGIRMA
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LGAQAGQVAWHVQRQGMTLVIAGLVIGTAGALVLTRYLSTLLFRVNPRDPVILGTAAMSL
ECCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHH
VAVSIVACWLPARRASRVDPLTALRNE
HHHHHHHHHCCHHHCCCCCCHHHHCCC
>Mature Secondary Structure 
SLAGNLKFTLRILRRNPALAISAILATGLGIGATSAMFSIADGILLHPLPFPKSDRLVN
CCCCCHHEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCCCCCCEEE
VWETAAARNIPRMVVAPGNYYDWRAQSHSFSALGAFQQSTFNLATGDAEPERLLGAIADP
HHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHCCC
GFFAALGVAPLLGRVCTEAENLPGGNAVVILSYALWQQRFGADRGILGRTLELNGRTRTV
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCEEEECCCEEEE
IGVMPQGFDFPAQSTIWSPLELDPPTMARRDFHRLRVIGRLKDGVSLEQARANFQTIAAG
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LAAQYPDFNAGETTTLNPMLEDLVGTVRPALLVLLGAVVAVLLIACANVANLLLAKASGR
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QREIAIRTSMGASRGAILGQMLTESTVLAVLGGITGLVLAKLALRGLISLAPASIPRLAE
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
ITLNGRVVGLGLALSLATGILFGLAPAWFAARVNVNGMLKEGMRGSSARNPLRSVLVAAQ
EEECCEEEEHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCCHHHHHHHHHHH
VAIALVLLSGAGLLIRSFYEVASVDAGFQPEHMMTMQLAPAITRYRGHPELQIQLARGIL
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
EKVSAIRGVRSAAVSTAVPLLGTPNYIMRFEGRAPVTPSQSPLTSYFGVTPAFFETMGMR
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
LLRGRLLNARDVQGAPLVVVVNQTLVDRYFPKQDPIGKRLEIGFSDPPNWREIVGVVADV
HHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
KTAGLDQQTPVQVYTAYLQTPSFPSSMISPITVMTRTEGDPGLLGAAMHAAILAVDRSQP
HHCCCCCCCCHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHEECCCCC
VYAIQPMTDIVAQSIAQRRLSLILLAFFAASAMLLAAIGVYGVMSFVVAQRTSEIGIRMA
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LGAQAGQVAWHVQRQGMTLVIAGLVIGTAGALVLTRYLSTLLFRVNPRDPVILGTAAMSL
ECCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHH
VAVSIVACWLPARRASRVDPLTALRNE
HHHHHHHHHCCHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA