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The map label for this gene is pqqL [C]

Identifier: 116620853

GI number: 116620853

Start: 2151811

End: 2154525

Strand: Direct

Name: pqqL [C]

Synonym: Acid_1734

Alternate gene names: 116620853

Gene position: 2151811-2154525 (Clockwise)

Preceding gene: 116620851

Following gene: 116620855

Centisome position: 21.59

GC content: 62.06

Gene sequence:

>2715_bases
ATGATTCGTAACAAGGGATTGATCCCGCTCACCCTCCTCCTCGCGATCTCCGCGCTGGCCCAGACCCTCCCCCCCGGCGT
GCAAAAAGTCACTTCCGTGGAAGGCATCACCGAGTACACCCTGCCTAACGGCTTGCACGTGCTCCTCTTCCCTGATGCCT
CCAAGCCGAACGTCACCGTCAACATGACCTACATGGTCGGTTCCCGTCTCGAAGGCTATGGAGAAACCGGCATGGCCCAC
CTGCTGGAGCACATGCTCTTCCTCCAGACCAAGACCCGCAAGGACGTCAAGCAGGAACTCAAGGACCACGGCGCAGAAAT
GAACGGTTCCACTTCCTGGGACCGCACCAACTACTTCGAGACCCTCACCGCCAGCGACGAAAACCTCAAGTTCGCCCTCG
AGCTCGAGGCCGACCGCATGGTCAACAGCAAAATCGAGAAGCAGCTTCTCGATACCGAAATGACCGTGGTCCGCAATGAA
TTCGAAATGGGCGAGAACAGCCCCGACCGCACGCTCATGCAGCGCGCCCTCGAAACCGCGTTCACCTGGCACAATTATGG
CAAGCTCCCCATCGGCAATCGCTCCGATATCGAAAATGTGCCGATCGCCCGTCTCGCTGCCTTTTATCAGAAGTATTACC
AGCCCGATAACGCCATCCTGACCGTTGCCGGTAAGTTCGATGAAGCCCAGACCCTGGCCCTCATCGCCAAGAACTTCGGC
CCCATCCCCAAGCCCACTCGTAAGCTCGAACAGTCCTATACGGTCGAGCCCACCCAGGATGGCGAACGGTCGGTGACCCT
CCGCCGTGTCGGCGATACCCAGGGCCTGGTGGCGCTCTACCACGTCCCCTCCGGCTCCCACCCCGATGCCGCCGCCCTCG
AGGTCCTCTCCGGCATGCTCGGCGATCGTCCCTCCGGCCGTCTCTACAAAGCCCTGGTCGATAACAAGAAGGCCGTCGGC
GCCTCCATGGGAATGGAAGAACTTCACGACCCCGGCTTCATCATGGCCTCGGCCAACCTCAAGCTCGATCAGTCGCTTGA
TGACGCCCGCCAGACTCTCCTCAAGGTCGTCGAAGGCGTGAGCTCCGAGCCCCCTACCAAGGAAGAGGTGGAGCGCGTCA
AGACGCGCCTGCTGAAAAATATCGAGCTCGAGATGGCCGATTCGCAATCCGTCGCGCTCGACCTCAGCGAATACTACTCG
CAGGGCGATTGGCGCCTCATGTTCCTCATGCGCGACCGCATTTCCAAGGTCACCCCGGAAGACGTGCTCCGCGTCGCCAA
GGCCTACCTGAAGGAATCCAACCGCACGCTCGCCACCTTCATTCCGACCAAGAATCCCGACCGCGCCGAAATCCCCGCCA
CCCCCGATATCGCCGCCACCCTGAAAGATTTCAAGGGTAGCGCGGTCGTGGCAGCGGGCGAGGCCTTCGACCCCAGCGTC
GCCAACATCGAATCGCGCGTGCAGCGCAGCACTCTGCCCGGCGGCGTCAAAGTCTCCCTGCTCCCGCGCAAGACCCGCGG
CGGCACCGTCGTCGCCACCCTCACCGTTCGCTATGGCGATGAGAAGGCGCTCTTCGGGAAGTCCGCCATCGCCGGTCTCA
CCGGCGGCATGCTGATGCGCGGCACCAAGACCCACACCCGTCAGCAGATCCAGGACGAAATGGATCGTCTCAAGGCGCAC
ATCAACGTGTCCGGCAGCGCGACTAGCGCCACCGCCAGCATCGAAACCGTAGAGGCCAACCTCCCCAACGCGCTCCGCCT
CGCCGTCGAAATCCTCCGCGAGCCGTCCTTCCCCGATAGCGAATTCGAAACCGTCAAGCAACAGCGCATCGCCGCCGCCG
AAGCCGGACGCAGCGAGCCGCAATCGCTCGCCATCACCGAGTTCCAGCACCGCCTCAACCCGTATCCCCGAGGCGACGTG
CGCTACGTCTCCACCGCCGATGAACAGATCGAGGACCTGAAGAAGGTCACCCTCGACGACGTCAAGAAATTCCACCAGCA
GTTCTACGGCGCCAGCGTCGGCGAGTTCGCCGTCTCAGGCCAGTTCAACCCCGCCGAGATCTCCAAGCTTGCGACGGATT
TATTCGGCAACTGGAAGAGCCCCGGATCCTACACCCGCCTCACCGCCAACTTCCATAAGGTGGATCCCACCGACAAGAAG
ATCCTCACTCCTGACAAGCAGAACGCCTTCTTCATCACCGGCCAGACCGTGAAGATGAGCGACGACGATCCCGACTATCC
CGCCATGATCATGGCCAACTACATGTTCGGCGGCAGCGGTCTCGGTACCCGCCTCTCGCGCCGCATCCGCGATAAGGAAG
GCCTCAGCTATGGCACCCAGTCGCAGTTCGGAGTTCCCACGAAAGATGACGGCGCGACCTTCCTGGCCCTCGCGATCAGC
AATCCCACGAACTCGCCGAAGGTGGAAGCCAGCTTCCGCGACGAACTCGCCAAGACCCTGAAGGAAGGCTTCACCGCCGA
CGAAGTCGCCGCCGCCAAGAAGGCCTGGCTGCAGGAACGCACCATGGGCCGCACCGAAGATGGCAGCCTGGTCGGCCTCC
TCGCCGCCCGCCAGCGCTTCGACCGCACTCTGAAATTCGATGAGTCGCTCGAATCCAAGGTCGCGTCGTTGACTCCCGAC
CAGATCAACGCCGCCTTCCGCAAATACATCGACCCCGCCGCCTTGACCTTCATCAAAGCCGGCGATTTCAAGTAG

Upstream 100 bases:

>100_bases
CCAAACCTAACGGCATACGTGTGCCCGCCCGAAGAAACCTGCCCTTGGCCCCAAACGTCCCTTGATATAATTCGTCTAAC
TCCCTCGATAAAGGTAGCTT

Downstream 100 bases:

>100_bases
GAACGAGCCGCGCGACCGTGAAGGAGCGTCCGTTTTTTGCGGCCTGCCGCCTTGTGCGGCAGCCAATCCTGGCTGCCGCC
GGCTTTCAGCCGGCGCACTA

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 904; Mature: 904

Protein sequence:

>904_residues
MIRNKGLIPLTLLLAISALAQTLPPGVQKVTSVEGITEYTLPNGLHVLLFPDASKPNVTVNMTYMVGSRLEGYGETGMAH
LLEHMLFLQTKTRKDVKQELKDHGAEMNGSTSWDRTNYFETLTASDENLKFALELEADRMVNSKIEKQLLDTEMTVVRNE
FEMGENSPDRTLMQRALETAFTWHNYGKLPIGNRSDIENVPIARLAAFYQKYYQPDNAILTVAGKFDEAQTLALIAKNFG
PIPKPTRKLEQSYTVEPTQDGERSVTLRRVGDTQGLVALYHVPSGSHPDAAALEVLSGMLGDRPSGRLYKALVDNKKAVG
ASMGMEELHDPGFIMASANLKLDQSLDDARQTLLKVVEGVSSEPPTKEEVERVKTRLLKNIELEMADSQSVALDLSEYYS
QGDWRLMFLMRDRISKVTPEDVLRVAKAYLKESNRTLATFIPTKNPDRAEIPATPDIAATLKDFKGSAVVAAGEAFDPSV
ANIESRVQRSTLPGGVKVSLLPRKTRGGTVVATLTVRYGDEKALFGKSAIAGLTGGMLMRGTKTHTRQQIQDEMDRLKAH
INVSGSATSATASIETVEANLPNALRLAVEILREPSFPDSEFETVKQQRIAAAEAGRSEPQSLAITEFQHRLNPYPRGDV
RYVSTADEQIEDLKKVTLDDVKKFHQQFYGASVGEFAVSGQFNPAEISKLATDLFGNWKSPGSYTRLTANFHKVDPTDKK
ILTPDKQNAFFITGQTVKMSDDDPDYPAMIMANYMFGGSGLGTRLSRRIRDKEGLSYGTQSQFGVPTKDDGATFLALAIS
NPTNSPKVEASFRDELAKTLKEGFTADEVAAAKKAWLQERTMGRTEDGSLVGLLAARQRFDRTLKFDESLESKVASLTPD
QINAAFRKYIDPAALTFIKAGDFK

Sequences:

>Translated_904_residues
MIRNKGLIPLTLLLAISALAQTLPPGVQKVTSVEGITEYTLPNGLHVLLFPDASKPNVTVNMTYMVGSRLEGYGETGMAH
LLEHMLFLQTKTRKDVKQELKDHGAEMNGSTSWDRTNYFETLTASDENLKFALELEADRMVNSKIEKQLLDTEMTVVRNE
FEMGENSPDRTLMQRALETAFTWHNYGKLPIGNRSDIENVPIARLAAFYQKYYQPDNAILTVAGKFDEAQTLALIAKNFG
PIPKPTRKLEQSYTVEPTQDGERSVTLRRVGDTQGLVALYHVPSGSHPDAAALEVLSGMLGDRPSGRLYKALVDNKKAVG
ASMGMEELHDPGFIMASANLKLDQSLDDARQTLLKVVEGVSSEPPTKEEVERVKTRLLKNIELEMADSQSVALDLSEYYS
QGDWRLMFLMRDRISKVTPEDVLRVAKAYLKESNRTLATFIPTKNPDRAEIPATPDIAATLKDFKGSAVVAAGEAFDPSV
ANIESRVQRSTLPGGVKVSLLPRKTRGGTVVATLTVRYGDEKALFGKSAIAGLTGGMLMRGTKTHTRQQIQDEMDRLKAH
INVSGSATSATASIETVEANLPNALRLAVEILREPSFPDSEFETVKQQRIAAAEAGRSEPQSLAITEFQHRLNPYPRGDV
RYVSTADEQIEDLKKVTLDDVKKFHQQFYGASVGEFAVSGQFNPAEISKLATDLFGNWKSPGSYTRLTANFHKVDPTDKK
ILTPDKQNAFFITGQTVKMSDDDPDYPAMIMANYMFGGSGLGTRLSRRIRDKEGLSYGTQSQFGVPTKDDGATFLALAIS
NPTNSPKVEASFRDELAKTLKEGFTADEVAAAKKAWLQERTMGRTEDGSLVGLLAARQRFDRTLKFDESLESKVASLTPD
QINAAFRKYIDPAALTFIKAGDFK
>Mature_904_residues
MIRNKGLIPLTLLLAISALAQTLPPGVQKVTSVEGITEYTLPNGLHVLLFPDASKPNVTVNMTYMVGSRLEGYGETGMAH
LLEHMLFLQTKTRKDVKQELKDHGAEMNGSTSWDRTNYFETLTASDENLKFALELEADRMVNSKIEKQLLDTEMTVVRNE
FEMGENSPDRTLMQRALETAFTWHNYGKLPIGNRSDIENVPIARLAAFYQKYYQPDNAILTVAGKFDEAQTLALIAKNFG
PIPKPTRKLEQSYTVEPTQDGERSVTLRRVGDTQGLVALYHVPSGSHPDAAALEVLSGMLGDRPSGRLYKALVDNKKAVG
ASMGMEELHDPGFIMASANLKLDQSLDDARQTLLKVVEGVSSEPPTKEEVERVKTRLLKNIELEMADSQSVALDLSEYYS
QGDWRLMFLMRDRISKVTPEDVLRVAKAYLKESNRTLATFIPTKNPDRAEIPATPDIAATLKDFKGSAVVAAGEAFDPSV
ANIESRVQRSTLPGGVKVSLLPRKTRGGTVVATLTVRYGDEKALFGKSAIAGLTGGMLMRGTKTHTRQQIQDEMDRLKAH
INVSGSATSATASIETVEANLPNALRLAVEILREPSFPDSEFETVKQQRIAAAEAGRSEPQSLAITEFQHRLNPYPRGDV
RYVSTADEQIEDLKKVTLDDVKKFHQQFYGASVGEFAVSGQFNPAEISKLATDLFGNWKSPGSYTRLTANFHKVDPTDKK
ILTPDKQNAFFITGQTVKMSDDDPDYPAMIMANYMFGGSGLGTRLSRRIRDKEGLSYGTQSQFGVPTKDDGATFLALAIS
NPTNSPKVEASFRDELAKTLKEGFTADEVAAAKKAWLQERTMGRTEDGSLVGLLAARQRFDRTLKFDESLESKVASLTPD
QINAAFRKYIDPAALTFIKAGDFK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=264, Percent_Identity=26.5151515151515, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI94538354, Length=433, Percent_Identity=23.7875288683603, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI155969707, Length=361, Percent_Identity=22.9916897506925, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1787770, Length=211, Percent_Identity=31.2796208530806, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17553678, Length=271, Percent_Identity=26.5682656826568, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=426, Percent_Identity=23.0046948356808, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357875, Length=431, Percent_Identity=23.6658932714617, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24646943, Length=431, Percent_Identity=23.6658932714617, Blast_Score=76, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 99679; Mature: 99679

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRNKGLIPLTLLLAISALAQTLPPGVQKVTSVEGITEYTLPNGLHVLLFPDASKPNVTV
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCEEE
NMTYMVGSRLEGYGETGMAHLLEHMLFLQTKTRKDVKQELKDHGAEMNGSTSWDRTNYFE
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
TLTASDENLKFALELEADRMVNSKIEKQLLDTEMTVVRNEFEMGENSPDRTLMQRALETA
EEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FTWHNYGKLPIGNRSDIENVPIARLAAFYQKYYQPDNAILTVAGKFDEAQTLALIAKNFG
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCC
PIPKPTRKLEQSYTVEPTQDGERSVTLRRVGDTQGLVALYHVPSGSHPDAAALEVLSGML
CCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
GDRPSGRLYKALVDNKKAVGASMGMEELHDPGFIMASANLKLDQSLDDARQTLLKVVEGV
CCCCCCHHHHHHHCCCHHHHHHCCHHHHCCCCEEEEECCCEECCCHHHHHHHHHHHHHCC
SSEPPTKEEVERVKTRLLKNIELEMADSQSVALDLSEYYSQGDWRLMFLMRDRISKVTPE
CCCCCCHHHHHHHHHHHHHHCCEEECCCCCEEEEHHHHHCCCCEEEEHHHHHHHHCCCHH
DVLRVAKAYLKESNRTLATFIPTKNPDRAEIPATPDIAATLKDFKGSAVVAAGEAFDPSV
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHH
ANIESRVQRSTLPGGVKVSLLPRKTRGGTVVATLTVRYGDEKALFGKSAIAGLTGGMLMR
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEEECCCHHHHCHHHHHHCCCCCEEC
GTKTHTRQQIQDEMDRLKAHINVSGSATSATASIETVEANLPNALRLAVEILREPSFPDS
CCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCH
EFETVKQQRIAAAEAGRSEPQSLAITEFQHRLNPYPRGDVRYVSTADEQIEDLKKVTLDD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHH
VKKFHQQFYGASVGEFAVSGQFNPAEISKLATDLFGNWKSPGSYTRLTANFHKVDPTDKK
HHHHHHHHHCCCHHCEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCC
ILTPDKQNAFFITGQTVKMSDDDPDYPAMIMANYMFGGSGLGTRLSRRIRDKEGLSYGTQ
EECCCCCCEEEEECCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
SQFGVPTKDDGATFLALAISNPTNSPKVEASFRDELAKTLKEGFTADEVAAAKKAWLQER
CCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TMGRTEDGSLVGLLAARQRFDRTLKFDESLESKVASLTPDQINAAFRKYIDPAALTFIKA
HCCCCCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHEEEEEC
GDFK
CCCC
>Mature Secondary Structure
MIRNKGLIPLTLLLAISALAQTLPPGVQKVTSVEGITEYTLPNGLHVLLFPDASKPNVTV
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCEEE
NMTYMVGSRLEGYGETGMAHLLEHMLFLQTKTRKDVKQELKDHGAEMNGSTSWDRTNYFE
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
TLTASDENLKFALELEADRMVNSKIEKQLLDTEMTVVRNEFEMGENSPDRTLMQRALETA
EEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FTWHNYGKLPIGNRSDIENVPIARLAAFYQKYYQPDNAILTVAGKFDEAQTLALIAKNFG
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCC
PIPKPTRKLEQSYTVEPTQDGERSVTLRRVGDTQGLVALYHVPSGSHPDAAALEVLSGML
CCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
GDRPSGRLYKALVDNKKAVGASMGMEELHDPGFIMASANLKLDQSLDDARQTLLKVVEGV
CCCCCCHHHHHHHCCCHHHHHHCCHHHHCCCCEEEEECCCEECCCHHHHHHHHHHHHHCC
SSEPPTKEEVERVKTRLLKNIELEMADSQSVALDLSEYYSQGDWRLMFLMRDRISKVTPE
CCCCCCHHHHHHHHHHHHHHCCEEECCCCCEEEEHHHHHCCCCEEEEHHHHHHHHCCCHH
DVLRVAKAYLKESNRTLATFIPTKNPDRAEIPATPDIAATLKDFKGSAVVAAGEAFDPSV
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHH
ANIESRVQRSTLPGGVKVSLLPRKTRGGTVVATLTVRYGDEKALFGKSAIAGLTGGMLMR
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEEECCCHHHHCHHHHHHCCCCCEEC
GTKTHTRQQIQDEMDRLKAHINVSGSATSATASIETVEANLPNALRLAVEILREPSFPDS
CCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCH
EFETVKQQRIAAAEAGRSEPQSLAITEFQHRLNPYPRGDVRYVSTADEQIEDLKKVTLDD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHH
VKKFHQQFYGASVGEFAVSGQFNPAEISKLATDLFGNWKSPGSYTRLTANFHKVDPTDKK
HHHHHHHHHCCCHHCEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCC
ILTPDKQNAFFITGQTVKMSDDDPDYPAMIMANYMFGGSGLGTRLSRRIRDKEGLSYGTQ
EECCCCCCEEEEECCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
SQFGVPTKDDGATFLALAISNPTNSPKVEASFRDELAKTLKEGFTADEVAAAKKAWLQER
CCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TMGRTEDGSLVGLLAARQRFDRTLKFDESLESKVASLTPDQINAAFRKYIDPAALTFIKA
HCCCCCCCCEEHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHEEEEEC
GDFK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]