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The map label for this gene is nmeDIMP [H]

Identifier: 116620819

GI number: 116620819

Start: 2120696

End: 2121955

Strand: Reverse

Name: nmeDIMP [H]

Synonym: Acid_1700

Alternate gene names: 116620819

Gene position: 2121955-2120696 (Counterclockwise)

Preceding gene: 116620820

Following gene: 116620818

Centisome position: 21.29

GC content: 56.9

Gene sequence:

>1260_bases
ATGGACACCCCGAAAATAGTACTTCAAAATGGTGCCGGCAGTCTCGCTCAGGTTGGAACGCGCCCTTTCGTCCATCTCCC
TAAAACACCGCCCCTGATTTCTTTTTTCACGGGCGGTGGTTTCTTGGACCTCGGTATGACCAGAGCAGGTTTCCCGATTG
CCTGGAGCCTAGAGCTTCAGGAAGCCTTCTGCGATGCCCATGACCATGGCATGGACGCTTTATTTGCTAGCCAGGGTATC
GCCGGGACCGCTCCTACCATCAGCTGCCGAGAGAGCATCAGATCAAAGGGTCCGGTCGCGATCCGTCGCGAGGCACTAGG
TACTCTCGCCCGCGGCGACGATTTCGGCATGATCGGAGGGCCGCCGTGCCCCGATTTCTCAGTGGGCGGAAAAAACAGAG
GATTTGCGGGTAATAAGGGGCAGCTAACGCAGTTATTCATCGAGCGCATTTGCGAGCTTGAGCCTTCATTCTTCCTGATT
GAGAACGTAAAGGGACTTATCAGCACCCGGGCTCATCGTGAGTTCCTTGATCGTGAGTTGTGGAAGCTGGAAGAAAAGGG
ATACGCCGTTGATCTCAGAGTCCTGAACGCCCTTGACCTTGGCGTTCCGCAGGATCGGGAACGCGTGTTCATCGTCGGGG
TACACCGAAGGATGATCAAGCGACTTTACGGCCTGCGGATGGACAAACGGCAGCGGGATTGGTTCCCGTGGCCGAAGGAC
TCCGCATTCGAACATGCCAAGACTCGTTTCTCCTGGCCTTCGACGTCTCCCTTCGGCGCCAATCCCCCATTGCCGGCAGG
CTTGCCCGAAGAGCTCTGCATGGCCCCTCTGATTTTGGACGTTGAGCAAACTGGCAGGCTCCCGAATGGCCAGGAGGGGT
TCGCACCTTACAGCGAGAAGTTCACGACGATCGCCGAAGGTGACGATTCAAGAAAATCTTTCAAGCGCCTGCACCGGTTC
CGCTACAGCCCCACTGCTGCTTATGGCAACAATGAGGTTCATCTTCATCCGGCGCAGCCCAGGCGATTGACGGTCCGGGA
AGCCATGAGGATTCAAACGGTACCTGATGGGTATGCGTTGCCACCGGAGATGCCGCTTTCGTTCAAATTCAAACTCATCG
GAAATGGGGTGCCCGTCCAGCTCGCCGCGGCGGTCGGTCATTCACTCAGACAGTTCATTTTGGGTGCGGGAACTCCGGTC
CTCCCCGGTGAGAAGGAGGCTAGTGCCAGTGCCCGCAGAGAAAATCAATCTCCAGCCTGA

Upstream 100 bases:

>100_bases
AGGGGCCAGATTGATTAAGACGGAAAACGCGATGGGCGTCAGGTCAGGGAGCGCTCTGAACGACGTTCGGCAGTTGTCAC
TGAGGTATGGTGACGCTACT

Downstream 100 bases:

>100_bases
TCCGCGAATCCTAATCGCAATCACTCGCAATCCAATGCGCCCGCTGGACGCGTTATGCGAGTTGATCGACAACAGTATTG
ACTCATTTGCTTCTGACGGA

Product: DNA-cytosine methyltransferase

Products: NA

Alternate protein names: M.NmeDIP; Cytosine-specific methyltransferase NmeDIP [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MDTPKIVLQNGAGSLAQVGTRPFVHLPKTPPLISFFTGGGFLDLGMTRAGFPIAWSLELQEAFCDAHDHGMDALFASQGI
AGTAPTISCRESIRSKGPVAIRREALGTLARGDDFGMIGGPPCPDFSVGGKNRGFAGNKGQLTQLFIERICELEPSFFLI
ENVKGLISTRAHREFLDRELWKLEEKGYAVDLRVLNALDLGVPQDRERVFIVGVHRRMIKRLYGLRMDKRQRDWFPWPKD
SAFEHAKTRFSWPSTSPFGANPPLPAGLPEELCMAPLILDVEQTGRLPNGQEGFAPYSEKFTTIAEGDDSRKSFKRLHRF
RYSPTAAYGNNEVHLHPAQPRRLTVREAMRIQTVPDGYALPPEMPLSFKFKLIGNGVPVQLAAAVGHSLRQFILGAGTPV
LPGEKEASASARRENQSPA

Sequences:

>Translated_419_residues
MDTPKIVLQNGAGSLAQVGTRPFVHLPKTPPLISFFTGGGFLDLGMTRAGFPIAWSLELQEAFCDAHDHGMDALFASQGI
AGTAPTISCRESIRSKGPVAIRREALGTLARGDDFGMIGGPPCPDFSVGGKNRGFAGNKGQLTQLFIERICELEPSFFLI
ENVKGLISTRAHREFLDRELWKLEEKGYAVDLRVLNALDLGVPQDRERVFIVGVHRRMIKRLYGLRMDKRQRDWFPWPKD
SAFEHAKTRFSWPSTSPFGANPPLPAGLPEELCMAPLILDVEQTGRLPNGQEGFAPYSEKFTTIAEGDDSRKSFKRLHRF
RYSPTAAYGNNEVHLHPAQPRRLTVREAMRIQTVPDGYALPPEMPLSFKFKLIGNGVPVQLAAAVGHSLRQFILGAGTPV
LPGEKEASASARRENQSPA
>Mature_419_residues
MDTPKIVLQNGAGSLAQVGTRPFVHLPKTPPLISFFTGGGFLDLGMTRAGFPIAWSLELQEAFCDAHDHGMDALFASQGI
AGTAPTISCRESIRSKGPVAIRREALGTLARGDDFGMIGGPPCPDFSVGGKNRGFAGNKGQLTQLFIERICELEPSFFLI
ENVKGLISTRAHREFLDRELWKLEEKGYAVDLRVLNALDLGVPQDRERVFIVGVHRRMIKRLYGLRMDKRQRDWFPWPKD
SAFEHAKTRFSWPSTSPFGANPPLPAGLPEELCMAPLILDVEQTGRLPNGQEGFAPYSEKFTTIAEGDDSRKSFKRLHRF
RYSPTAAYGNNEVHLHPAQPRRLTVREAMRIQTVPDGYALPPEMPLSFKFKLIGNGVPVQLAAAVGHSLRQFILGAGTPV
LPGEKEASASARRENQSPA

Specific function: This methylase recognizes a double-stranded sequence, causes specific methylation on a C on both strands, and protects the DNA from cleavage by the NmeDIP endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 46226; Mature: 46226

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPKIVLQNGAGSLAQVGTRPFVHLPKTPPLISFFTGGGFLDLGMTRAGFPIAWSLELQ
CCCCCEEEECCCCCHHHHCCCCEEECCCCCCEEEEECCCCEEECCCCCCCCCEEEEEEHH
EAFCDAHDHGMDALFASQGIAGTAPTISCRESIRSKGPVAIRREALGTLARGDDFGMIGG
HHHHCHHHCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCC
PPCPDFSVGGKNRGFAGNKGQLTQLFIERICELEPSFFLIENVKGLISTRAHREFLDREL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
WKLEEKGYAVDLRVLNALDLGVPQDRERVFIVGVHRRMIKRLYGLRMDKRQRDWFPWPKD
HHHHHCCCEEEEEEEHHHHCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCC
SAFEHAKTRFSWPSTSPFGANPPLPAGLPEELCMAPLILDVEQTGRLPNGQEGFAPYSEK
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEHHHHCCCCCCCCCCCCHHHC
FTTIAEGDDSRKSFKRLHRFRYSPTAAYGNNEVHLHPAQPRRLTVREAMRIQTVPDGYAL
EEEEECCCCHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCEEEHHHHHEEEECCCCCCC
PPEMPLSFKFKLIGNGVPVQLAAAVGHSLRQFILGAGTPVLPGEKEASASARRENQSPA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MDTPKIVLQNGAGSLAQVGTRPFVHLPKTPPLISFFTGGGFLDLGMTRAGFPIAWSLELQ
CCCCCEEEECCCCCHHHHCCCCEEECCCCCCEEEEECCCCEEECCCCCCCCCEEEEEEHH
EAFCDAHDHGMDALFASQGIAGTAPTISCRESIRSKGPVAIRREALGTLARGDDFGMIGG
HHHHCHHHCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCC
PPCPDFSVGGKNRGFAGNKGQLTQLFIERICELEPSFFLIENVKGLISTRAHREFLDREL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
WKLEEKGYAVDLRVLNALDLGVPQDRERVFIVGVHRRMIKRLYGLRMDKRQRDWFPWPKD
HHHHHCCCEEEEEEEHHHHCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCC
SAFEHAKTRFSWPSTSPFGANPPLPAGLPEELCMAPLILDVEQTGRLPNGQEGFAPYSEK
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEHHHHCCCCCCCCCCCCHHHC
FTTIAEGDDSRKSFKRLHRFRYSPTAAYGNNEVHLHPAQPRRLTVREAMRIQTVPDGYAL
EEEEECCCCHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCEEEHHHHHEEEECCCCCCC
PPEMPLSFKFKLIGNGVPVQLAAAVGHSLRQFILGAGTPVLPGEKEASASARRENQSPA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10671450 [H]